Mycobacterium sp. MCS: Mmcs_0263
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Entry
Mmcs_0263 CDS
T00367
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
mmc
Mycobacterium sp. MCS
Pathway
mmc00860
Porphyrin metabolism
mmc01100
Metabolic pathways
mmc01110
Biosynthesis of secondary metabolites
mmc01120
Microbial metabolism in diverse environments
mmc01240
Biosynthesis of cofactors
Module
mmc_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mmc_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mmc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Mmcs_0263
Enzymes [BR:
mmc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Mmcs_0263
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Peripla_BP_6
Motif
Other DBs
NCBI-ProteinID:
ABG06384
UniProt:
A0A5Q5BDZ5
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All DBs
Position
complement(302767..303915)
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AA seq
382 aa
AA seq
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MSEPDWAPLTGFRVAVTSARRAEELSALLRRRGATVTSAAAIAMVPLPDDDELRAHTQAL
IDAPPDIVIATTGIGLRGWIAAADGWGVAAELTAALAGARIVSRGPKATGALRAAGLPEE
WSPDSESSREVLRYLLDGGIADKRIAVQLHGATDDWDPFPEFLDELRAAGADVVPIRVYR
WRPAPRDGDFDQLVAGIAEEKFDAVSFTSAPAVASVLMRATEMGVADRVLTALRTNVHAM
CVGPVTARPLVRLGVPTSAPERMRLGALARHITDELPLLQARTVRVAGHLLEIRGTCVLV
DGVVKSLSPAGMATIRALAHRPGAVVSRTDLLGALPGSGTDTHAVETAVLRLRTALGDKQ
IVSTVVKRGYRLTVDDDLAEAL
NT seq
1149 nt
NT seq
+upstream
nt +downstream
nt
atgagtgagcctgactgggcaccgctcaccggattccgggtggcggtgacctccgcccga
cgcgccgaggagctgagcgcactgctgcgccgccgcggcgccaccgtcaccagcgcggcc
gcgatcgcgatggtgccgctacccgacgacgacgaactgcgcgcccacacccaggcactg
atcgacgcaccgcctgacatcgtgatcgcgaccaccgggatcgggctgcgcggctggatc
gccgccgccgacggctggggcgtcgccgccgaactcaccgcggccctggcgggggcccgc
atcgtctcccgcggacccaaggcgaccggcgcgctccgggccgccggcctgcccgaggag
tggtcaccggattcggagtcgtcccgggaggtgctgcgctatctgctcgacggcggcatc
gccgacaagcgcatcgccgtccagttgcacggcgccaccgacgactgggaccccttcccc
gaattcctcgacgaactgcgggccgcgggcgccgacgtggtgccgatccgggtgtaccgc
tggcgtccggcaccccgcgacggcgacttcgaccagttggtggcgggcatcgccgaggag
aagttcgatgccgtcagcttcacctccgcaccggctgtggcgtcggtgctcatgcgggcc
accgagatgggtgtcgccgaccgggtgctgacggccctgcggaccaacgtgcacgcgatg
tgcgtcggcccggtcaccgcgcgtcccctggtccggctcggggttccgacgtcggcgccg
gagcgcatgcggttgggtgcgctggcccgccacatcaccgacgaactgccactgttgcag
gcccgcaccgttcgggtggccggacacctgctcgagatccgcggtacctgcgtactcgtg
gacggtgtggtcaaatcgctgtccccggccgggatggccaccatccgcgcactcgcgcac
cggcccggcgcggtggtgtcgcgcaccgacctgcttggcgcattgcccggcagcggcacc
gacacccacgctgtcgagaccgcggtgctgcggctgcgaaccgcgttgggcgacaagcag
atcgtctccacggtcgtcaaacgcggataccggctcaccgtcgacgacgatctggcggag
gccctgtga
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