Mycobacterium sp. MCS: Mmcs_1921
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Entry
Mmcs_1921 CDS
T00367
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mmc
Mycobacterium sp. MCS
Pathway
mmc00290
Valine, leucine and isoleucine biosynthesis
mmc00660
C5-Branched dibasic acid metabolism
mmc01100
Metabolic pathways
mmc01110
Biosynthesis of secondary metabolites
mmc01210
2-Oxocarboxylic acid metabolism
mmc01230
Biosynthesis of amino acids
Module
mmc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mmc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Mmcs_1921
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Mmcs_1921
Enzymes [BR:
mmc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Mmcs_1921
4.2.1.35 (R)-2-methylmalate dehydratase
Mmcs_1921
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
DUF6127
Motif
Other DBs
NCBI-ProteinID:
ABG08030
UniProt:
Q1BAQ4
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All DBs
Position
2066462..2067907
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AA seq
481 aa
AA seq
DB search
MAQPATPRTMAEKVWADHVVAHGIGEGAAREPDLIYIDLHLVHEVTSPQAFDGLRLANRP
VRRPDLTIATEDHNVPTVDIDKPIADPVSRTQVETLRRNCAEFGIRLHPMGDAEQGIVHI
IGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFRTMAVNV
DGELPPGVSAKDIILAVIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARA
GMVAPDDTTFEFLRGRPHAPTGADWDAAVEAWRQLRTDPGAEFDTEVHLDAAELSPFVTW
GTNPGQGVPLSGAVPDPELIVDEGERQAAEKALTYMGLQAGTAMRDVAVDTVFVGSCTNG
RIEDLRVVADVLRGRRVADGIRMLVVPGSMRVRAQAESEGLDRIFIDAGAEWRQAGCSMC
LGMNPDQLSPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLSAVPA
R
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atggcacagcccgccacaccgcgcaccatggccgagaaggtgtgggccgaccacgtcgtc
gcccacggcatcggggagggtgccgcgcgtgaaccggatctgatctacatcgacctgcac
ctcgtgcacgaggtgaccagtccgcaggcgttcgacggtctgcggctggcgaaccggccg
gtgcgacggccggatctcaccatcgcgaccgaagaccacaacgtgccgacggtcgacatc
gacaagccgatcgccgacccggtgtcgcgcacccaggtggagacgttgcggcgcaactgc
gccgagttcgggatccggctgcacccgatgggcgacgccgaacagggcatcgtgcacatc
atcggtccgcagctcgggctcacccagccggggatgaccgtcgtgtgcggtgacagccac
acctccacccacggcgcgttcggcgccctggcgatgggtatcggcacctccgaggtggaa
cacgtgctggcgacgcagacgctgccgctgcggccgtttcgcacgatggcggtcaacgtc
gacggggaactgccgccgggcgtgagcgccaaggacatcatcctggcggtcatcgccaag
atcggcaccggcggcggacagggccacgtcatcgaataccgcggcagcgccatcgaatcc
ctgtcgatggagggccggatgacgatctgcaacatgagcatcgaggccggcgcgcgggcc
ggcatggtggcccccgacgacaccacattcgaattcctgcgcggccgcccgcacgcaccc
accggcgccgactgggatgcggcggtggaggcgtggcggcagctgcgcaccgatccgggc
gccgaattcgacaccgaggtccatctcgacgcggccgagctgagcccgttcgtcacctgg
ggcaccaaccccgggcagggggtgccgctgtccggcgcggtgcccgaccctgagctgatc
gtcgacgagggtgagcgacaggcggccgaaaaggcgttgacctacatgggtcttcaggcc
ggtacggcgatgcgtgacgtcgccgtggacaccgtgttcgtcggatcgtgcaccaacggc
cgcatcgaggatctgcgcgtggtggccgacgtcctgcgtggccgcagggtcgccgatggg
atccgcatgctcgtggtgcccggctcgatgcgcgtgcgtgcgcaggccgaatccgaaggg
ctcgaccggatcttcatcgacgccggtgccgaatggcggcaggcgggctgctcgatgtgc
ctggggatgaaccccgatcagctgtcgcccgggcagcggtgcgcatccacgtccaaccgc
aacttcgaggggcgccagggcaaaggcgggcggacacatctggtctcacccgccgtggct
gccgccaccgccgtccgcggcacgctgtcctcacccgccgacctgtccgccgtccccgct
cgctga
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