Mycobacterium sp. MCS: Mmcs_4109
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Entry
Mmcs_4109 CDS
T00367
Name
(GenBank) 3-beta hydroxysteroid dehydrogenase/isomerase
KO
K16045
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mmc
Mycobacterium sp. MCS
Pathway
mmc00984
Steroid degradation
mmc01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mmc00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
Mmcs_4109
Enzymes [BR:
mmc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
Mmcs_4109
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
Mmcs_4109
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_10
GDP_Man_Dehyd
RmlD_sub_bind
NAD_binding_4
NmrA
Polysacc_synt_2
KR
adh_short
Motif
Other DBs
NCBI-ProteinID:
ABG10214
UniProt:
A0A5Q5BPP1
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Position
4376060..4377175
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AA seq
371 aa
AA seq
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MADATLTTELGRVLVTGGSGFVGANLVTELLERGHHVRSFDRAPSPLPPHPLLETLEGDI
CDPETVAAAVAGVDTVFHTAAIIDLMGGASVTDEYRRRSFAVNVGGTENLVRAGRAAGVK
RFVYTASNSVVMGGQPIVAGDETLPYTDRFNDLYTETKVAAEKYVLAQNGIDGMLTCSIR
PSGIWGRGDQTMFRKVFESVLAGHVKVLVGSKNVKLDNSYVHNLIHGFILAAEHLVPGGT
APGQAYFINDGEPVNMFEFSRPVVEACGERYPRLRVPGRLVHFVMTVWQKLHFRFGLPKP
LLEPLSVERIYLDNHFSIAKAERDLGYRPLFTTEQAMQACLPYYVELYEKMKADGAKTPA
VQAVRTTPPAG
NT seq
1116 nt
NT seq
+upstream
nt +downstream
nt
atggctgatgcaacgctgaccacagaactgggccgcgtgctggtgaccggtgggtccggc
ttcgtgggcgcgaatctcgtgaccgaactgctcgagcgcggccaccacgtgcgttcgttc
gaccgcgccccctccccgctgccaccccatccgctgctggagacgctcgaaggcgacatc
tgcgatccggagacggtggccgccgcggtcgccggcgtcgacaccgtcttccacaccgcg
gcgatcatcgacctgatgggcggggcgtcggtcaccgacgagtaccgccgccgcagtttc
gcggtcaacgtcggaggcaccgagaacctcgtgcgcgcgggccgcgccgccggggtgaag
cggttcgtctacaccgcgtccaacagcgtggtgatgggcggacagccgatcgtcgccggc
gacgagaccctgccctacaccgaccggttcaacgacctctacaccgagaccaaggtggcc
gcggagaagtacgtcctggcgcagaacgggatcgacggaatgctgacgtgctcgatccgg
ccgagcggcatctggggccggggcgatcagacgatgttccgcaaggtgttcgaatccgtc
ctggccggacacgtcaaggttctcgtcgggagcaagaacgtcaaactcgacaactcgtac
gtgcacaacctcattcacggtttcatcctcgccgccgaacacctggtgcccggcggcacg
gcacccggtcaggcgtatttcatcaacgacggggagccggtcaacatgttcgagttctcc
cgcccggtcgtggaggcgtgcggtgagcgttatccgcggttgcgggtgccgggccggctc
gtgcacttcgtgatgacggtctggcagaaattgcacttccgcttcgggctgcccaaaccg
ttgctggaaccgctgagcgtggaacggatctatctcgacaaccacttctcgatcgcgaag
gcggaacgggatctgggctaccgcccgctgttcaccaccgagcaggcgatgcaagcctgc
ctgccgtattacgtcgagctgtacgagaagatgaaggccgacggagcgaaaacccctgcc
gtacaagcggtgcggaccacaccgccggcgggttga
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