Methylophilus medardicus: FIU01_10695
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Entry
FIU01_10695 CDS
T10472
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mmec Methylophilus medardicus
Pathway
mmec00300
Lysine biosynthesis
mmec00550
Peptidoglycan biosynthesis
mmec01100
Metabolic pathways
mmec01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mmec00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FIU01_10695
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FIU01_10695
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FIU01_10695
Enzymes [BR:
mmec01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FIU01_10695
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF4349
Motif
Other DBs
NCBI-ProteinID:
QDC44944
UniProt:
A0A5B8CUF2
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Position
complement(2254615..2255979)
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AA seq
454 aa
AA seq
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MIALSDIATVLHGTLQGEDVTVTSVDTDSRRAQPGQLFVALPGEKFDGHDFLSQVATQGA
VAALVSRPVDSPLPTVLVKDTRLALGQLASWWRQQWALPLIAVTGSNGKTTTKEMIADIL
QVHSGRADAVLATAGNFNNDIGMPLTLLRLRPTHRHAVIEMGMNHLGEIDYLTRLACPDV
AVINNAGTAHIGELGSRENIAKAKGEIFAGLRSDGVAVINADSAFADYWRGLNTARRVVT
FGLDANADVRGVMLDAASSFTLHYQHQAVQVTLAVPGVHNVMNALAAAATSLAAGVPLAD
VGLGLQQFAGVNGRLQKKTAANGAVVIDDTYNANPDSMRAALEVLKNAGQNTLFVMGDMG
ELGADAEDMHAQIGRYAKTCGVNKLYALGKFTQAAVQAFGQPAQHFATLETLLAALQAEM
QADDVVLVKGSRFMQMERVVNALVALQTTDIGAE
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgattgcgctatccgacatcgcaacagtgttgcacggtactttgcagggtgaagatgtc
acggtgacgtcggtcgatacagacagtcgtcgtgcgcagcccggacaattgtttgtcgca
ttgccgggcgaaaagtttgatggacatgactttttatcgcaagtggctacgcaaggcgca
gtggctgccttggtgagtcggccggtagatagtcctctgccaaccgtgctggtcaaagat
acgcgattggcattgggtcagttggccagttggtggcgtcagcagtgggcattgccgctg
atagcagtgactggcagcaatggcaaaaccaccaccaaagaaatgattgccgacattctg
caagtgcatagtggccgcgcggacgcggtgttggccactgccggtaattttaataatgac
atcggcatgccgctgacgttgttgcgtttgcgtcccacccatcgtcatgccgtgatcgaa
atgggcatgaatcatttaggtgagattgactacctgacgcgcctggcctgcccagatgtg
gctgtcatcaacaatgcaggcactgcccatattggggaactgggttcgcgtgaaaacatt
gccaaagccaaaggcgagattttcgcaggcttgcgcagtgatggcgttgcggtaatcaat
gccgatagtgcttttgctgactactggcgcggcttgaataccgctagacgggtggtgacg
tttgggctggatgcaaatgcagatgtgcgtggcgtgatgttggatgctgcgtctagcttt
acattgcattatcaacatcaggctgtgcaagtcacattggctgtgcccggtgtgcataac
gtgatgaatgcactcgctgcggcggcaaccagtctggcagctggcgtgcctctggcagac
gtggggctgggtttgcaacagtttgccggggtcaacgggcgtttacaaaaaaagactgcg
gccaatggtgcagtcgtgattgatgacacttacaacgccaaccctgactccatgcgcgcg
gcgctagaggtgctgaaaaatgcgggccagaacaccttatttgtgatgggcgacatgggg
gagcttggcgctgatgctgaagacatgcatgcacaaataggccggtatgccaaaacgtgc
ggggtgaacaagttatatgcattgggcaagttcacacaagcggcggtgcaggcattcggc
cagccagcgcaacattttgccacgttggagacgttgttagccgctttgcaggcagaaatg
caagccgacgacgtggtgttggtaaaaggctcgcgctttatgcaaatggagcgcgtagta
aatgcgttagtggcgttgcaaaccactgatataggggcggaatag
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