Candidatus Mycobacterium methanotrophicum: M5I08_01120
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Entry
M5I08_01120 CDS
T08748
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mmeh
Candidatus Mycobacterium methanotrophicum
Pathway
mmeh00290
Valine, leucine and isoleucine biosynthesis
mmeh00620
Pyruvate metabolism
mmeh01100
Metabolic pathways
mmeh01110
Biosynthesis of secondary metabolites
mmeh01210
2-Oxocarboxylic acid metabolism
mmeh01230
Biosynthesis of amino acids
Module
mmeh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mmeh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
M5I08_01120 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
M5I08_01120 (leuA)
Enzymes [BR:
mmeh01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
M5I08_01120 (leuA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
UQX11193
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All DBs
Position
complement(216126..218000)
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AA seq
624 aa
AA seq
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MRRSPPLRRPSSFSGATTVTSSSQPSGDSPDVFKSVRTIIKPAGQPNAGQPAWNTQRGSS
MPISRYRSVAEEVEPVQLVDRTWPDNVLTRAPLWCAVDLRDGNQALIDPMSPARKRRMFE
LLVRMGYKEIEVGFPAASQTDFDFVRQIIAEGAIPDDVTIQVLTQCRPELIERTFAACEG
ARRVIVHFYNSTSILQRRVVFRAGRAAVRAIATDGAHKCVEEAAKYPGTQWRFEYSPESY
TGTELEYAKQVCDAVGEIIAPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESV
ILSLHPHNDRGTAVAAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQI
DFSNIDEIRRTVEYCNQLPVPERHPYGGDLVYTAFSGSHQDAINKGLDAMKVAADEADSD
VDDMLWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSGV
IQKISEGEGGEVSPKAMWDAFAEEYLAPVRPLERIKQRVEASDVDYGATLIAATVKIDGV
ETEISGSGNGPLAAFVDALGTVGFDVAVLDYSEHAMSAGDDAQAAAYVEASVAGKVVWGV
GIAPSITTASLRAVVSAVNRAARH
NT seq
1875 nt
NT seq
+upstream
nt +downstream
nt
atgcgccggtcgccgccactcaggcgcccctcctcattctccggagcaacaaccgtgact
agctcttctcaaccgtcgggcgactcccctgacgtattcaagtccgttcgaacgatcatc
aaacccgccggccaacccaacgcgggccagccggcctggaacacccagcgtgggtcatcg
atgccgatcagccggtaccggtcagtcgccgaggaagtcgagccggtccagctggtcgac
cgtacctggcccgacaacgtactcacccgcgcgccgctgtggtgcgcggtggacctgcgc
gacggcaaccaggcgctgatcgacccgatgagcccggcccgcaagcggcgcatgttcgag
ctgctggtccgcatgggctacaaggaaatcgaagtcggcttcccggccgccagccagacc
gatttcgacttcgtccgccagatcatcgccgagggcgccatccccgacgacgtcaccatc
caggtgctgacccagtgccgtccggagctgatcgaacgaacctttgcggcgtgcgaggga
gcgcgccgcgtgatcgtgcacttctacaactcgacgtcgatcttgcagcgccgggtggtt
ttccgcgccggccgggccgcggtccgggccatcgcgaccgacggcgcgcacaagtgcgtc
gaggaggccgcgaagtatccgggcacgcagtggcggttcgagtactcgccggagtcctac
accggcactgagctggaatacgccaagcaggtctgcgacgccgtcggcgagatcatcgcc
ccgacgccggacaacccgatcatcttcaacctgcccgccacagtggagatggccacgccg
aacgtctacgccgactcgatcgagtggatgagccgcaacttggcgaaccgggaatcggtc
atcctgagcctgcacccgcacaacgaccgcggaaccgccgtcgccgcagccgaattgggc
taccaagccggtgcggaccgcatcgagggctgcctgttcggcaacggcgagcggaccggg
aacgtctgcttggtgacgctgggcctgaacttgttctcccgcggtgtcgacccgcagatc
gacttctccaacatcgacgagatccgtcgcacagtcgagtactgcaaccagctgccggtc
cctgaacgtcacccgtacggcggcgacctggtttacacggcgttctccggcagccaccaa
gacgccatcaacaagggcctggatgcgatgaaggtggcagccgatgaggcggattccgat
gtcgacgacatgctctggcaggtgccgtatctgccgatcgatccgcgcgacgtcgggcgc
acctacgaggcggtgatccgagtcaattcgcagtcgggcaagggcggggtggcctacatc
atgaaggccgatcacggcctggcgttgccgcgacggctacagatcgaattctccggcgtg
attcagaaaatcagcgaaggggaaggcggcgaggtcagccccaaggcgatgtgggatgcg
tttgccgaggagtacttggcgccggtgcgaccgctggagcggatcaagcagcgggtcgag
gcatccgacgtggactacggcgcgaccctgatcgcggcgacggtcaagatcgatggggtg
gagacggagatcagcggttcgggcaacggcccgctcgccgcgttcgtcgatgcgctgggc
accgtcggtttcgacgtggccgtgctggattactccgagcacgcgatgagcgccggcgac
gacgcgcaggccgccgcgtacgtggaggcgtcggtggccggcaaggtcgtgtggggcgtg
ggcatcgcgccgtcgatcaccaccgcgtcgctgcgcgccgtggtctcggcggtgaatcgg
gccgcgcgacactga
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