Molossus molossus (Pallas's mastiff bat): 118617075
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Entry
118617075 CDS
T07221
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mmf
Molossus molossus (Pallas's mastiff bat)
Pathway
mmf00230
Purine metabolism
mmf00670
One carbon pool by folate
mmf01100
Metabolic pathways
mmf01523
Antifolate resistance
Module
mmf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mmf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118617075 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
118617075 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118617075 (GART)
Enzymes [BR:
mmf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
118617075 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
118617075 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
118617075 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
ATP-grasp_3
CPSase_L_D2
ATP-grasp_4
CbiJ
Dala_Dala_lig_C
DUF3104
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
118617075
NCBI-ProteinID:
XP_036098504
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVLGGGGREHALAWKLAQSSHVQQVLVAPGNAGTACSAKISNAAISSSDHSALAQ
FCKDQNIEFVVVGPEAPLAAGIVGNLAAAGVRCFGPSAQAAQLESSKRFAKEFMDRHGIP
TARWRAFTEPEEACSFIMSADVPALVVKASGLAAGKGVIVAGSREEACRAVQEIMQDKTF
GAAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLDGDRGPNTGGMGAYCPAP
QVSKDLLQRITNTILQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCASPPVWLGNCTAVTVVMASHGYPGDYTKGVEITGVAEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIREDLIAALEGAKKGLAAIKFEGAVYRKD
IGYRAIAFLKQPRGLTYKDSGVDIAAGNLLVEKIKPLAKATSRPGCNVDLGGFAGLFDLK
AAGFKDPLLVSGTDGVGTKLKVAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLGTAAAVVAGIAKACGKAGCALLGGETAEMPDMYPPGDYDLAGFAVGAVERGQKLP
VLDAIAEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDNCGDQTLGDLLLTPTR
IYSQSLLPVLHSGHVKAFAHITGGGLLENIPRVLPSKCGVDLDAQTWRIPKIFSWLQQEG
QLSEEEMARTFNCGIGAALVVSKDLTEQVLRDIQQHQEEAWVIGRVVACPEGSPRVRVRH
LVQAMRINGSVLENGTMKSHFSAQPKKARVAVLISGTGSNLQALIDSTQEPSSAAHIAVV
ISNKPEVAGLDKAARAGIPTRVINHKLYKSRVEFDTAVNQVLEEFFIDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFRGSNAHEQALGAGVTVTGCTVHFVAEEVDAGQIILQEA
VPVKRGDTVATLSERVKLAEHKIFPTALQLVASGAVRLGEDGRLCCVQDE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcggcccgggtgctcgtgcttggcggtgggggcagagagcacgcgctggcctggaaa
ctcgcgcagtccagccacgtccagcaggtgttggtcgcgcccggaaacgcaggcactgcc
tgctctgcgaagatctcaaatgctgccatctcctccagcgatcacagtgccctggctcag
ttctgcaaagatcagaacattgaattcgtagttgttggaccagaggcacctctggctgct
gggattgtggggaacctggcagctgcaggagtgcgatgctttggcccctcggcacaagcg
gctcagttagagtccagcaaaaggtttgccaaagagtttatggaccgacatggaatccca
acggcacggtggagagcgttcaccgaacctgaggaggcctgcagcttcatcatgagcgca
gacgtccctgctttggttgtgaaggccagcggtcttgcggccgggaagggggtgattgtg
gcaggcagcagagaagaggcctgcagagctgtgcaggagatcatgcaggataaaaccttt
ggagcagctggagaaacagttgtcattgaagaacttcttgaaggagaagaggtttcttgt
ctgtgcttcactgatgggagaactgtggctcccatgcccccagcccaggaccataagcga
ctgctggacggggatcgcggccccaacacaggggggatgggggcctactgtccggcacct
caggtttctaaggatttgttgcaaaggattacaaacaccattctccagaggacggtggat
ggcatgcagcaggagggcacgccgtacacaggtattctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaattgccgtttcggtgatccagagtgtcaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcagtccaccttagatggcctg
ctgtgcgcatctccgcctgtgtggcttggaaactgtacagctgtaactgttgtcatggca
agtcacggttatccaggagactacaccaagggtgtggagataacaggggttgccgaggct
caggcgttagggctggaggtgttccaagctggtacggccctgaaagatggcaaagtggtg
actaatggaggtcgagtcctcacggtaacagccatccgggaagatctcatcgcggccctt
gaaggagccaagaaaggactggctgctatcaagtttgagggagccgtttacaggaaggac
attggctatcgagccatagccttcctcaagcagcccaggggcctgacttacaaggactct
ggagtagacattgcagctggaaatctgctggtcgagaaaattaaacctttagcaaaagca
acctccagaccaggctgtaacgttgatcttggaggttttgctggtctctttgatttgaaa
gcagccggtttcaaagatcctctcctggtctctggaacagacggcgttggaacaaaactg
aaggttgcccagcagtgcaataaacatgataccattggtcaagatttggttgcaatgtgt
gtgaatgatatcctggcacaaggagcagagcccctcttcttccttgattacttctcctgt
ggcaaactggacctcggtacagccgcagctgttgttgctggaatcgccaaagcctgtggg
aaagcgggctgcgcgctcctcggaggtgaaacagcagagatgccagacatgtaccctcct
ggggactatgacctggccgggtttgccgtgggagcggtggagcggggtcagaaactcccc
gtcctggatgcgattgctgaaggggatgttgtagttgggatcgcttcatctggtcttcac
agcaatggattcagcctcgtgaggaaaattgtagcgaaatcttcccttcagtactcttct
ccggcacctgataactgtggcgaccagaccttaggggacttacttctgactccaaccaga
atctacagccagtccctgttacctgtcttacattcaggacacgtcaaggcctttgcccac
atcactggtggagggctactagagaacatccccagagtcctcccttcaaaatgtggggtg
gatttagatgctcagacctggaggatccctaaaatcttctcgtggttacagcaggaagga
cagctctctgaagaagagatggccagaacatttaactgtgggatcggggctgccctggtg
gtatccaaggacctgacggagcaggttctgagggacattcagcagcaccaggaagaagcc
tgggtgattggcagagtggtggcctgccctgaaggttcccctcgtgtgagagtcaggcac
ctggttcaagccatgcggataaatgggtcagtgttggagaatggcaccatgaaaagtcac
ttttctgcccaaccaaaaaaggcaagagtagctgtcttaatatctggaacaggatcgaac
ctccaagctctcatagacagtactcaggagccaagtagtgctgcacacatcgctgttgtt
atctccaacaaacccgaggtggccgggctagataaagcagcgagagcaggcattcccacc
agagtaattaatcataagttatataaaagtcgtgtagaatttgacactgcagtcaaccaa
gtccttgaagagttcttcatagacatagtctgtcttgcaggattcatgagaattttatct
ggtccctttgtcagaaaatggaatgggaaaatgctcaacatccatccatccttgctccct
tcttttaggggttcaaatgcccacgagcaagccctgggcgccggcgtcacagtgactggg
tgcactgtgcactttgtagctgaagaagtggatgctggacagattattttacaagaagct
gttccagtgaagaggggtgatactgttgccactctgtctgaaagagtgaaactggcagaa
cataaaatctttcccacagccctgcagctggtggccagtggggctgtccggctcggtgag
gacggcaggctctgttgtgtccaggatgagtga
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