Molossus molossus (Pallas's mastiff bat): 118624172
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Entry
118624172 CDS
T07221
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
mmf
Molossus molossus (Pallas's mastiff bat)
Pathway
mmf05012
Parkinson disease
mmf05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmf00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
118624172 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
118624172 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmf01001
]
118624172 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmf04131
]
118624172 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmf04147
]
118624172 (LRRK2)
Enzymes [BR:
mmf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
118624172 (LRRK2)
Protein kinases [BR:
mmf01001
]
Serine/threonine kinases: TKL group
LRRK family
118624172 (LRRK2)
Membrane trafficking [BR:
mmf04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
118624172 (LRRK2)
Exosome [BR:
mmf04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
118624172 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
LRR_14
Beta-prop_EML_2
Arf
WDR55
LRR_9
LRR_13
Beta-prop_RSE1_2nd
AAA_22
LRR_NXF1-5
GTP_EFTU
T2SSE
nSTAND3
WD40_Prp19
WD40_CDC20-Fz
PduV-EutP
Beta-prop_WDR19_1st
ABC_tran
AAA_7
LRR_6
MMR_HSR1
Ank_2
Septin
NACHT
AAA_16
G-alpha
Pox_A32
cobW
Kdo
TrwB_AAD_bind
AAA_29
FtsK_SpoIIIE
SRPRB
MobB
TsaE
ResIII
AAA_23
TniB
AAA_33
Motif
Other DBs
NCBI-GeneID:
118624172
NCBI-ProteinID:
XP_036108106
LinkDB
All DBs
Position
Unknown
AA seq
2525 aa
AA seq
DB search
MASGSCQECEEEETLKKLIVRLNNLQEGKQIETLVQILDDILVFTYSDHASNLFQGKNVH
VPLLIVLDSYMRVACVQQVGWSLLCKLIEICPDTMRSLTGPQDIGHDWEVLGVHQLIIKM
LTVHNTNITLSTVGLKALELLLTSGKITLLILDEESDIFLLIFDAMRTFSASDEVQKLGC
KTLYVLFERVSEEQLTEFVENKDYMILLSALNNFKDEEEIVLCVLHCLHSLAIPCSNVEV
LMSGNVRCYNIVVEAMKAFPTNEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVTAAQR
YATNARLQIAALGCLALLTETIFLNQDLEEKNENQENEEEEEEEKLFWLEACYKALTWHR
KNKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASANA
LSTLLEQNVNFRKILLSKGIYLNVLELMQKHAPSPEVAESGCKMLSHLFEGSNASLDIMA
AVAPKIIAVMKSHATSSSVQLEALRAILHFIAPGMPEEFTENAEYQNKLHMVTKQCIRND
IHKLVLVSLNRFIGNPGIQKCGLKVISSLAHFPDALEVLSVEGAIESVLQTLQMYPDDQE
IQFLGLSLIGCLITKKNLFLGTGHLLAKILVSSLQRFKDIAELQMKGFQTVLTVLELSVS
FSKLLVRYSFDSVIFHQMSSCLMEQKDRQFLNLCCKCFAKLAMDDDLKNVMLERACDQNN
SIMAECLLLLGADANRAKEGTSLICQVCEKASSPKLVELLLNSGSREQDVREALTISIGK
GDSQTISLLLRRLALDLANNSICLGGFCMGKIEPSWLGPLFPDKTPNSRKETNMGSTLAR
MVLRYQMKSAEAEGAASGSEGTFPEQVLDKFDEWTFIPESYGDSVFSQSDDLDSEGSEVS
FLGKKKSNSISVGEFYRDPALHRSPDSQRHSNSLGPIFDHEDVLKQKRKILSSDDLLRSS
KLPSHMRHSDSASSLASEREYITSLDLSANELRDIDALSQKCCLSGHLEHLERLELHQNA
LTAFPQRLCETLKCLTHLDLHSNKFSSFPSYLLKMNCIAYLDVSRNDIGPSIVLDPAVKC
PTLKQFNLSYNQLSSVPKHLGEVAQTLELLTLEGNKISGMCSPLSLKELKILNLSKNHIS
SLSEDFLEACPKVESLSARMNFLAAMPFLPSSMTSVKLSQNRFTCVPEAILNLPHLRSLD
MSNNDIKYLPNPAHWKSLNLRELLFSHNQISILDLSEKAYIWSRMEKLHLSHNKLKEIPP
EIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDIIRFL
QQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSTTVGIDVKDWPFQIRG
KKKKDLTLNVWDFAGSEEFYSTHPHFMTPRSLYLAVYDLSKGEAEVDAMKPWLFNIKARA
SSSPVILVGTHLDVSDEKQRKACVSKINRELLNKRGFPAIRNYHFVNATEESDALAKLRK
TIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPTEFPVIDRKRLLQLVKENQL
ELDENELPHAIHFLNESGVLLHFQDPALQLSNLYFVEPKWLCKVMAQILTLKVEGCPKHP
QGIISRRDVEKFLSKKKRFPKNQMQKYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVIEL
PHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLLGREQALRPNRMYWRQGIYLNW
SPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDYCG
EGETLLKKWALYSFNDGEEHKKILLDDLMKKAEEGDLLVNPDQPRVTIPISQIAPDLILA
DLPRNIMLNSDKLEFKQAPEFLLGDGSFGSVYRATYEGEEVAVKIFNKHTSLRLLRQELV
VLCHLHHPSLVSLLAAGIRPRMLVMELASKGSLDRLLQHDKANVTRTLQHRIALHVADGL
RYLHSAMIIYRDLKPHNVLLFTLYPNAAVIAKIADYGIAQYCCRMGIKTSEGTPGFRAPE
VARGNVIYNHQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKEYGCA
PWPMVEKLIKRCLKENPQERPTSAQVFDILNSAELICLMRQISIPKTFTVECMVAAHPGS
KNASVWLGCGHRNKGQLSFLDLTTERLTFEEVTDSRILCLALVHLPVDKESWVVCGTQSG
ALLVIDTDDGKRRHTLEKMTDSITCLHYSSFAKPSKQKSFLLVGTADGNLAIFEDKTVKC
KGAAPLTILNIGNISTPLMCLSESVNSTEKNIMWGGCGTKLFSFSDDFTIQKLIETRTSQ
LFSNATSNNSNIIAVVVDTALYIAKKNSSFVEVWDKKTEKLCELIDCLQFLKQEMVKVNT
EPKHNLAYWGRVKTLCLQKNTALWVGTGGGCMLLLDLSTRRVIRIIRNFCDSVRVLMAAQ
LGSLKNAMLVLGYTRKSTEGMQQQKELQSCLSIWDINLPHEVQNLEKHIEMRKELAEKMR
KTTVD
NT seq
7578 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgtcaggagtgcgaggaggaggaaactttgaagaagttgatagtc
aggctgaacaatctccaggaaggaaaacagattgagacgctggtccaaattctggatgat
atactggtgttcacctactccgaccacgcctccaatttatttcaaggcaaaaatgtccac
gtgcctctgttgatcgtcttggactcgtatatgagagtcgcttgtgtgcagcaggtgggt
tggtcacttctatgcaaattaatagaaatctgtccagatacaatgcgaagcttaacgggc
cctcaggatattggacacgattgggaagtccttggtgttcaccaactgatcattaagatg
cttacagttcataataccaatataacactgtcaacggttggactgaaggccttagaactc
cttctaacttcaggtaaaatcactttgctgatattggatgaagaaagcgatattttctta
ctaatttttgatgccatgcgaacattttcagccagtgacgaggtccagaaacttggatgc
aaaactttgtatgtgctgtttgagagagtttcggaggagcaactgactgaatttgttgag
aataaagattatatgatattgctaagtgcattaaacaactttaaagatgaggaggaaatt
gtgctttgtgtactgcactgtttacattccctagcaattccttgcagtaatgttgaagtc
ctcatgagtggcaacgtcaggtgttataatattgtggtagaagctatgaaggcattccct
accaatgaaaaaattcaagaagtgagttgctgcttgctccataggcttacattaggtaac
ttttttaatatcctggtgttgaacgaggtccacgagtttgtggtgacagccgcgcagcgg
tacgcgacgaatgcccggctgcagatcgcggcgctcggctgcttggcgctcctgactgag
accattttcttaaatcaagacttagaggaaaagaatgaaaatcaggagaatgaagaggag
gaggaagaagagaaattgttttggctggaggcctgttacaaagccttaacatggcacaga
aagaacaaacatgtgcaggaggctgcatgctgggccctcaacaatctccttatgtaccaa
aacagtttgcacgagaagattggagatgaagatggccagttcccagctcacagggaagtg
atgctgtccatgctgatgcattcttcatcaaaggaagtctttcaggcatctgcgaacgca
ttgtcgactctcctagaacagaatgttaatttcagaaaaatcctgttgtccaaaggaata
tacctgaacgtgctggagttaatgcagaagcacgcgccttctcctgaagtggcggaaagc
ggctgtaaaatgctaagtcatcttttcgaaggaagtaatgcgtccctggatataatggca
gcagtggcccccaaaataatagcagttatgaaaagtcatgcgacatcatcatcagtgcag
ctggaggcacttagagctattttacattttatagctcctggtatgccagaagaattcaca
gaaaatgccgaatatcaaaacaagctacatatggttacaaaacagtgtatcaggaatgac
attcacaaactggttctagtatctttaaacaggttcattggaaatcctgggattcagaaa
tgtggattaaaagtaatttcttctctagcacattttcctgatgcattagaagtgttatct
gtggaaggtgctattgaatcggtgcttcagacattgcaaatgtatccggacgaccaagaa
attcagtttctgggtttaagtcttataggatgcttgattacaaaaaagaatttattcctg
ggaactggacatctgctggcaaaaattctggtttccagtttacagagatttaaggacatt
gctgaattacagatgaaaggatttcagacagtcttgaccgtgctggaattgtccgtgtct
ttttccaagctgttggtgcgttactcctttgattcagtaatattccatcagatgtcttcc
tgtctcatggaacaaaaggatagacagtttctcaacctttgttgcaagtgctttgcaaag
ttagctatggatgatgacttgaaaaatgtgatgctggagagggcatgtgatcagaacaac
agcatcatggcggaatgcttgcttctgttgggagcagatgccaatcgagcaaaggagggg
acttctttaatttgtcaggtatgtgaaaaagcgagcagtcccaaactggtggaactgtta
ctgaatagtgggtcccgtgaacaagatgtacgggaagcgctgacgataagcattgggaaa
ggcgacagccaaaccatcagtttgctcttgaggaggcttgccctggatctggccaataac
agcatatgcctcggaggattttgcatgggaaaaatcgaaccttcgtggcttggtccttta
tttccagataaaacacccaattcaagaaaagaaacaaatatgggatccaccctcgcaagg
atggtcctgcgataccagatgaaaagtgccgaggcagagggagcagcctcgggcagcgaa
gggactttccctgaacaagtgcttgataagtttgatgaatggaccttcattcctgagtct
tacggggacagtgtgttcagtcaaagcgatgacctagatagtgaagggagtgaagtttca
tttcttgggaaaaagaagtcaaactcaattagcgtaggagagttttaccgggatcctgcc
ttgcatcgctcaccagattcgcaaaggcattccaattccttgggacccatttttgatcat
gaagatgtactgaagcaaaaaagaaaaatactgtcttcagatgatttactcaggtcatca
aaacttccatcccatatgaggcattcagacagtgcttcttccctggcttctgagagagaa
tatattacatcattggatctttcagccaatgaactgagagatattgacgccctcagccag
aaatgctgtctaagcggtcatctggagcacctggaaaggctggagcttcaccagaacgca
ctcacggccttcccgcaacgcctctgtgaaacgctgaagtgtctgacacacttggacttg
cacagcaataaattctcgtcgtttccctcctacttgttgaaaatgaattgcattgcctac
cttgatgtctctcgaaacgacattggaccctccatagttttggatcccgcagtgaagtgt
ccgaccttgaagcagtttaacctgtcatataaccagctgtcttccgtgcccaagcacctt
ggggaggtggcacagacactggaactgctcactttggaaggaaataaaatatcaggcatg
tgttctcctctgagcctgaaggaactgaagattttaaaccttagtaaaaaccacatttcg
tccctgtcagaagacttcctggaggcttgccctaaagtggagagtctcagtgccaggatg
aattttcttgctgctatgccttttttaccttcttctatgacaagtgtaaaattatctcaa
aacagatttacatgtgttccagaagcaattttaaatcttccacatttgcgatccttggat
atgagcaacaatgatattaaatatctaccaaatcctgcacactggaaatctctgaactta
agggaactcttgtttagtcataatcagatcagcatcttggacttgagtgaaaaagcatat
atatggtctagaatggagaaactacatctttctcataataaactgaaagagattcctcct
gagatcggctgtcttgaaaatctgacgtcccttgatgttagttacaacttggaactgaga
tcctttcccaatgaaatggggaaactgagcaaaatatgggatcttcctttggatgaactg
cgtcttaattttgactttaagcatataggatgtaaagccaaagacatcataaggtttctt
caacagaggttaaaaaaggctgtgccctataaccgaatgaaacttatgattgtgggaaat
actgggagtggtaaaaccaccttattgcagcaattaatgaaaaccaagaaatcagatctt
gggatgcaaagtaccacagttggcatcgatgttaaagactggcctttccaaataagaggc
aaaaagaagaaagacctcactctaaacgtgtgggattttgcaggtagtgaggaattctac
agcactcatccccacttcatgaccccgcgatctctgtacctcgccgtctatgacctcagc
aaaggggaagcagaagttgacgccatgaagccctggctgttcaatataaaggctcgcgcc
tcttcttccccggtgattctggtgggcacgcacctggatgtttccgacgagaagcagcgc
aaagcctgcgtgagtaagatcaacagggagctgctgaacaagcgcggctttcccgccatc
cggaactaccacttcgtcaacgccaccgaggaatccgacgccttggccaaacttcgcaaa
accatcatcaacgagagcctgaacttcaagatccgagaccagcctgttgttgggcagctg
attccagactgctatgtggaactcgagaaaatcattttatcagagcgaaaaaatgtgcca
actgagtttcctgtcattgaccgaaaacgcttattacaactcgtgaaagaaaatcaactg
gagttagacgaaaacgagcttcctcatgcaatccacttcctaaatgaatcaggggtcctt
cttcatttccaagacccagcactgcagttaagtaacttatactttgtggaacccaagtgg
ctttgtaaagtcatggcacagattttgacactgaaagtggaaggctgtccaaaacatcct
caaggaattatttcacgtcgagatgtggaaaaatttctttcaaagaaaaagagatttcca
aagaaccagatgcaaaagtactttaaactcctagaaaaatttcagattgccttgccaata
ggagaagaatatttgctggttccaagcagtttgtctgaccacaggcctgtgatagaacta
cctcattgtgagaactctgaaattatcattcgactatatgaaatgccttattttcccatg
ggattttggtcaagattaatcaatcgattacttgaaatttcaccttatatgctactaggc
agagaacaagcacttcgcccaaacagaatgtattggcgacaaggcatctacttgaattgg
tctccggaagcttattgtctggtaggatctgaagtcttagataatcatccagaaagtttc
ttaaaaattacagttccttcttgtagaaaaggctgtattcttttggggcaagttgtggac
cacatcgattctctcatggaagaatggtttcctgggttattggagatagattattgtggt
gaaggagaaactttattgaagaaatgggcattatatagttttaatgatggtgaagaacat
aaaaaaatcttacttgatgacttgatgaagaaagcagaagaaggagacctcctagtaaat
ccagatcaaccaagggtcaccattccaatctctcagattgctcctgatctgattctagct
gacctgcctagaaatattatgttaaatagtgataagttggaatttaaacaagctccggag
tttctcttaggcgatggcagttttggatcagtttatcgagcaacctatgaaggagaagaa
gtggctgtaaagatttttaataaacatacatcacttagactgttacgacaagagctggtg
gtgctttgccacctccaccaccccagcttggtatctctgctggcggctgggattcgccct
cggatgctggtgatggagctggcctccaagggctccctggaccgcctgctgcagcacgac
aaagccaatgtcacgaggaccctgcagcaccggatcgcgctgcatgtggctgacggcttg
agatacctgcactcggccatgattatataccgtgatctgaagccccacaatgtactgctc
ttcaccttgtatcccaacgctgccgtcattgcaaagattgctgactatgggatcgctcag
tactgctgcagaatggggataaaaacatcagagggcaccccagggtttcgtgcacctgaa
gttgctagaggaaatgtaatttataaccatcaggctgatgtttattcatttggtttacta
ctgtatgacattttgacaactggaggtagaatagcagagggcttgaagtttccaaatgag
tttgatgaattggcaatacaaggaaaattaccagatccagttaaagaatatggttgtgcc
ccatggcctatggtcgagaagttaattaaaaggtgtttaaaagaaaatcctcaagaaaga
cctacttctgcccaggtctttgacattttgaattcagccgagttaatctgtctaatgaga
cagatatcaatccctaaaaccttcactgtggaatgcatggttgctgcacatcctggcagc
aagaatgcaagtgtctggctgggctgcgggcacagaaacaaaggacagctctcctttctt
gacttgactactgaaagactcactttcgaggaagttactgatagcagaatactgtgccta
gccttagtgcacctgcctgtggacaaggaaagctgggtcgtgtgtgggactcagtctggc
gcactccttgtcattgacactgacgacgggaaaaggagacatacccttgaaaagatgacc
gattccattacttgcttgcattacagttcctttgccaagccaagcaagcaaaaaagtttt
cttttggtgggaactgctgatggcaacttagcgatttttgaagataaaactgttaagtgt
aaaggtgctgctcctttgacgatcctcaatataggaaacatcagcactccgctcatgtgt
ttgagtgaatctgtgaattcaacagaaaagaacattatgtggggaggatgtggcacaaaa
cttttctcgttttctgatgatttcaccattcagaaactcattgagaccagaacaagtcag
ctgttttctaatgcaacttccaacaattccaacatcatagcggtggtggtagacacagcc
ctctacattgctaagaaaaacagctcgtttgtggaagtgtgggataagaaaactgaaaaa
ctttgtgaactgatagactgtttgcagtttttaaagcaggaaatggtgaaagtaaacaca
gagcccaaacacaacctggcttactgggggagagtgaaaactctgtgtctgcagaagaac
acggcgctctgggtcggcaccggaggaggctgcatgctgctccttgatctgtcaactcgc
cgagtcatacgtataattcgcaacttttgtgattctgttagggtgctgatggccgcacag
ttaggaagccttaaaaatgccatgttggttttggggtatacccggaaaagtactgaaggt
atgcaacaacaaaaagaattacaatcttgtttgtctatttgggacatcaatcttccacat
gaagtgcaaaatttagagaaacatattgaaatgagaaaagaattagctgaaaaaatgagg
aaaacaactgttgattaa
DBGET
integrated database retrieval system
