KEGG   Molossus molossus (Pallas's mastiff bat): 118625236
Entry
118625236         CDS       T07221                                 
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC isoform X1
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
mmf  Molossus molossus (Pallas's mastiff bat)
Pathway
mmf00230  Purine metabolism
mmf00670  One carbon pool by folate
mmf01100  Metabolic pathways
mmf01523  Antifolate resistance
Module
mmf_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:mmf00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    118625236 (ATIC)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    118625236 (ATIC)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    118625236 (ATIC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmf04147]
    118625236 (ATIC)
Enzymes [BR:mmf01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     118625236 (ATIC)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     118625236 (ATIC)
Exosome [BR:mmf04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   118625236 (ATIC)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS Ribosomal_L12_N
Other DBs
NCBI-GeneID: 118625236
NCBI-ProteinID: XP_036109909
LinkDB
Position
Unknown
AA seq 592 aa
MAPGQLALFSVSDKTGLVEFARNLTSVGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVVCNLYPFVKTVASPDVTVEEA
VEQIDIGGVALLRAAAKNHARVTVVCGPEDYAAVAAEMRTSDRKDTSLETRRQLALKAFT
HTAQYDEAISDYFRQQYSKGMSQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELREALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDMHKTLTPLS
TAYARARGADRMSSFGDFVALSDICDVPTAKIISREVSDGIVAPGYDEEALKILSKKKNG
NYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNGVINRSLFSNVVTKNKDLPEPALRDLIV
ATVAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANFWWLRHHPRVLSMKFQT
GVKRAEISNAIDQYVTGTIGEGEDLVKWKALFEEVPELLTEAEKKEWIDKLCDVSVSSDA
FFPFRDNVDRAKRSGVAFIAAPSGSAADKVVIEACDELGIVLAHTSLRLFHH
NT seq 1779 nt   +upstreamnt  +downstreamnt
atggcgcccggccagctcgccttatttagtgtctctgacaaaaccggccttgtggagttt
gccagaaacctcacctctgttggtttgaatctggtcgcttctggagggactgcaaaagct
ctcagggatgccggtctggcagtcagagatgtctctgagctgacggggtttcctgaaatg
ttaggcggacgcgtgaaaaccttgcatcctgcagtccacgctggaatcttggctcgtaat
atcccagaagataatgcagacatggccagacttgatttcaatcttataagagttgtggtt
tgtaatctttatccctttgtgaagacggtggcttctccagatgtaactgttgaagaggct
gttgagcaaattgatattggtggagtggcactgctgagagcagcagccaagaaccacgcc
cgagtgaccgtcgtgtgtggacccgaggactacgccgccgtggccgcagagatgcggacc
tccgacaggaaagacacctccttggagactaggcgccagttggccttgaaggctttcacc
cacacggcacagtacgacgaagccatctcagactacttcaggcaacagtatagtaaagga
atgtctcagatgcccttgaggtacggcatgaaccctcatcagactccagcccagttgtac
acactgaaacccaagcttcccatcacagttctaaatggagcccctggattcataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcagagaagccttaggcattcca
gccgctgcctctttcaagcacgtcagcccagcaggcgccgctgttggaattccacttagt
gaagacgaggccaaagtgtgcatggtctatgacatgcataagacccttacgcccctgtcg
actgcatatgcgcgagcaagaggggctgatagaatgtcttcatttggtgactttgttgca
ttatctgatatatgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggatatgatgaagaagctttgaaaatactttctaaaaagaaaaatggc
aactactgtgttcttcagatggaccagtcttataatccagatgaaaatgaagttcgaact
ctatttggtcttcgtttaagccagaagagaaataatggtgtcatcaataggtcattattt
agcaatgttgttaccaagaataaagatttgccggaacccgcgctcagagacctcattgtg
gccaccgttgctgtgaagtacacccagtccaactccgtgtgctatgccaagaacggtcag
gttattggcatcggagcaggacagcagtctcggatccactgcacccgcctggcaggagat
aaagcgaacttctggtggcttagacatcatcctcgggtgctctccatgaagttccaaacc
ggagtcaagagagcagaaatctccaacgccatcgatcagtacgttaccggaaccatcggc
gagggtgaagatttagtaaagtggaaggcgctgtttgaggaagtccctgaattactaacc
gaggcagagaagaaggaatggatcgacaaactttgtgacgtttctgtcagctcggatgcc
ttcttccctttcagggataacgtagacagagctaagaggagtggcgtggcctttattgct
gccccgtccgggtctgctgctgacaaggtcgtgattgaggcctgcgatgaactggggata
gtcctcgctcacacgagtcttcggctcttccatcactga

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