KEGG   Molossus molossus (Pallas's mastiff bat): 118628278
Entry
118628278         CDS       T07221                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mmf  Molossus molossus (Pallas's mastiff bat)
Pathway
mmf00562  Inositol phosphate metabolism
mmf01100  Metabolic pathways
mmf04015  Rap1 signaling pathway
mmf04020  Calcium signaling pathway
mmf04022  cGMP-PKG signaling pathway
mmf04062  Chemokine signaling pathway
mmf04070  Phosphatidylinositol signaling system
mmf04071  Sphingolipid signaling pathway
mmf04072  Phospholipase D signaling pathway
mmf04081  Hormone signaling
mmf04082  Neuroactive ligand signaling
mmf04261  Adrenergic signaling in cardiomyocytes
mmf04270  Vascular smooth muscle contraction
mmf04310  Wnt signaling pathway
mmf04371  Apelin signaling pathway
mmf04540  Gap junction
mmf04611  Platelet activation
mmf04613  Neutrophil extracellular trap formation
mmf04621  NOD-like receptor signaling pathway
mmf04713  Circadian entrainment
mmf04720  Long-term potentiation
mmf04723  Retrograde endocannabinoid signaling
mmf04724  Glutamatergic synapse
mmf04725  Cholinergic synapse
mmf04726  Serotonergic synapse
mmf04728  Dopaminergic synapse
mmf04730  Long-term depression
mmf04742  Taste transduction
mmf04750  Inflammatory mediator regulation of TRP channels
mmf04911  Insulin secretion
mmf04912  GnRH signaling pathway
mmf04915  Estrogen signaling pathway
mmf04916  Melanogenesis
mmf04918  Thyroid hormone synthesis
mmf04919  Thyroid hormone signaling pathway
mmf04921  Oxytocin signaling pathway
mmf04922  Glucagon signaling pathway
mmf04924  Renin secretion
mmf04925  Aldosterone synthesis and secretion
mmf04926  Relaxin signaling pathway
mmf04927  Cortisol synthesis and secretion
mmf04928  Parathyroid hormone synthesis, secretion and action
mmf04929  GnRH secretion
mmf04933  AGE-RAGE signaling pathway in diabetic complications
mmf04934  Cushing syndrome
mmf04935  Growth hormone synthesis, secretion and action
mmf04961  Endocrine and other factor-regulated calcium reabsorption
mmf04970  Salivary secretion
mmf04971  Gastric acid secretion
mmf04972  Pancreatic secretion
mmf04973  Carbohydrate digestion and absorption
mmf05010  Alzheimer disease
mmf05016  Huntington disease
mmf05017  Spinocerebellar ataxia
mmf05022  Pathways of neurodegeneration - multiple diseases
mmf05142  Chagas disease
mmf05143  African trypanosomiasis
mmf05146  Amoebiasis
mmf05163  Human cytomegalovirus infection
mmf05200  Pathways in cancer
mmf05415  Diabetic cardiomyopathy
mmf05417  Lipid and atherosclerosis
Module
mmf_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mmf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    118628278 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    118628278 (PLCB3)
   04310 Wnt signaling pathway
    118628278 (PLCB3)
   04371 Apelin signaling pathway
    118628278 (PLCB3)
   04020 Calcium signaling pathway
    118628278 (PLCB3)
   04070 Phosphatidylinositol signaling system
    118628278 (PLCB3)
   04072 Phospholipase D signaling pathway
    118628278 (PLCB3)
   04071 Sphingolipid signaling pathway
    118628278 (PLCB3)
   04022 cGMP-PKG signaling pathway
    118628278 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    118628278 (PLCB3)
   04081 Hormone signaling
    118628278 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    118628278 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118628278 (PLCB3)
   04613 Neutrophil extracellular trap formation
    118628278 (PLCB3)
   04621 NOD-like receptor signaling pathway
    118628278 (PLCB3)
   04062 Chemokine signaling pathway
    118628278 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    118628278 (PLCB3)
   04922 Glucagon signaling pathway
    118628278 (PLCB3)
   04929 GnRH secretion
    118628278 (PLCB3)
   04912 GnRH signaling pathway
    118628278 (PLCB3)
   04915 Estrogen signaling pathway
    118628278 (PLCB3)
   04921 Oxytocin signaling pathway
    118628278 (PLCB3)
   04926 Relaxin signaling pathway
    118628278 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    118628278 (PLCB3)
   04918 Thyroid hormone synthesis
    118628278 (PLCB3)
   04919 Thyroid hormone signaling pathway
    118628278 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    118628278 (PLCB3)
   04916 Melanogenesis
    118628278 (PLCB3)
   04924 Renin secretion
    118628278 (PLCB3)
   04925 Aldosterone synthesis and secretion
    118628278 (PLCB3)
   04927 Cortisol synthesis and secretion
    118628278 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118628278 (PLCB3)
   04270 Vascular smooth muscle contraction
    118628278 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    118628278 (PLCB3)
   04971 Gastric acid secretion
    118628278 (PLCB3)
   04972 Pancreatic secretion
    118628278 (PLCB3)
   04973 Carbohydrate digestion and absorption
    118628278 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    118628278 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    118628278 (PLCB3)
   04725 Cholinergic synapse
    118628278 (PLCB3)
   04728 Dopaminergic synapse
    118628278 (PLCB3)
   04726 Serotonergic synapse
    118628278 (PLCB3)
   04720 Long-term potentiation
    118628278 (PLCB3)
   04730 Long-term depression
    118628278 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    118628278 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    118628278 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    118628278 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    118628278 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118628278 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    118628278 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    118628278 (PLCB3)
   05142 Chagas disease
    118628278 (PLCB3)
   05143 African trypanosomiasis
    118628278 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118628278 (PLCB3)
   05016 Huntington disease
    118628278 (PLCB3)
   05017 Spinocerebellar ataxia
    118628278 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    118628278 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118628278 (PLCB3)
   05415 Diabetic cardiomyopathy
    118628278 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    118628278 (PLCB3)
   04934 Cushing syndrome
    118628278 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmf04131]
    118628278 (PLCB3)
Enzymes [BR:mmf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     118628278 (PLCB3)
Membrane trafficking [BR:mmf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    118628278 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    118628278 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 118628278
NCBI-ProteinID: XP_036115033
LinkDB
Position
Unknown
AA seq 1229 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSQNLVTLRVDSNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPRDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWAEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLGPSQTRLLIEKYEPNQQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSTGVPSS
SVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEAGLEKPSLEPRKSLGE
EGPQRGPDLGPADREEEEEEDEEEEQSDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVK
FKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMP
QLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVD
GIVANALRVKVISGQFLSDRKVSIYVEVDMFGLPVDTRRKFRTRTSQGNSFNPVWDEEPF
DFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLIY
TEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGEREAQAGPETCQETQCQQQG
SQLTPNPTPSPLDTSPRRPPGPVTSPTSPSLSSPGQRDDLIASILSEVVVAPLDELRGHK
ALVKLRSRQERDLRELHKKHQRKAFALTRRLLDSLAQAQAENRCRHRPGVLGREDEREEE
EEMKRYREFQKRQVQSLLELREAQADAEAERRMEHLRQALQRLREIVLDAHTTQVKRLKE
MNDREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLEEAQKQ
RHERLMAGQQQVLQQLVEEEPKLLAQLAQECQEQRARLPQEIRRSLLGETPEGLGDGHLV
ACASNGHAPGSSGHLSGADSESQEENTKL
NT seq 3690 nt   +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtggtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaagcctccagtcagaacctg
gtgaccttgcgagtggactccaatggcttcttcctatactggacaggacccaacatggag
gtggacacactggacatcagttccatcagggacacgcggacgggtcgttatgcccgcctg
cccagggaccccaagatccgcgaggtgctgggttttggggggcctgatgcccggctagaa
gagaagctgatgacagtggtggctgggccagacccagtgaacacaacattcttgaacttc
atggccgtgcaggatgacacagccaaggtctgggctgaggagctgttcaagctggctatg
aacatcttggctcagaacgcctccaggaacaccttcctgcgcaaagcatacacaaaactg
aagctgcaggtaaaccaggatggacggatcccagttaagaacatcctgaagatgttctca
gcagacaagaagcgggtagagactgcactggagtcctgtggcctcaattttaaccggagc
gagtccatccggcctgatgagttttccttggaaatctttgaacggttcctgaacaagttg
tgtcttcggccggacattgacaagatcctgctggagataggtgccaagggtaagccatac
ctgacgctggagcagctcatggacttcatcaaccagaagcaacgggacccaagactcaat
gaagtgctgtacccaccgctggggccctcccagacccggctgctcattgagaagtatgag
cccaaccagcagttcctggagcgagaccagatgtccatggagggcttcagccgctacctg
ggcggtgaggagaacggcatcctgcccctagaggccctggatctgagtgcagacatgacc
cagccgctgagcgcctacttcatcaactcctcacacaacacctatctcacagcgggacag
ctggctgggacctcgtcggtggagatgtaccgccaggcgctgctgtggggctgccgctgt
gtggagctggatgtgtggaaagggcggccgccggaggaggagccctttatcacccacggt
ttcaccatgaccacggaggtgccactgcgggatgtgctggaggccatcgctgagaccgcc
ttcaagacctcgccctacccggtcatcctctccttcgagaaccacgtggactcggcaaag
cagcaggccaagatggccgagtactgtcgctctatcttcggggatgcgctactcattgac
ccactggacaagtacccgctggccccgggcgtccccttgcccagcccccaggacctgatg
ggccgcatcctagtgaagaacaagaagcggcaccggcccagcactggcgtccccagcagc
tctgtgcgcaagcggccgctggagcagagtaactcggcgctgagcgagagctccgccgcc
acggaaccctcctcgccccagctcgggtcccccagctccgacagctgccccggcctgagc
aacggggaggaggcaggcctagagaaacccagcctggagcctcggaagtctctgggtgag
gaggggccacagcggggccctgatcttggacctgctgaccgtgaggaggaggaggaggag
gatgaagaggaggaacagtcagaccccaaaaagccgaccacagatgagggtactgctagc
agtgaggtcaatgctactgaggaaatgtcaacactcgtcaactacatcgagcctgtcaag
ttcaagtcctttgaggctgctcgaaagaggaacaagtgcttcgagatgtcatccttcgtg
gagaccaaggccatggaacagctgaccaagagccctatggagtttgtggaatacaacaag
cagcagctcagccgcatctaccccaagggcacccgtgtggactcatcgaactacatgccc
cagctcttctggaatgtgggctgccagctcgtggcactcaactttcagaccctggatgtg
gcgatgcagctcaacgcaggcgtgttcgagtacaatgggcgcagtggctacctgctcaag
cctgagttcatgaggcggccagacaagtcttttgaccccttcaccgaggtcatcgtggac
ggcatcgtggccaatgccttgcgggtcaaggtgatctccggacagttcctgtccgacagg
aaggtgagcatctacgtggaggtggatatgttcggcctccccgtcgacacgcgtcgcaag
ttccgaactcggacctctcaggggaactctttcaaccccgtgtgggatgaggagcccttt
gacttccccaaggtggtgctgcccactctggcttcgctgcgcatcgcggcctttgaggag
ggtggcaaattcgtggggcaccggatcctgcctgtctctgccatccgctcaggataccac
tacatctgcctaagaaacgaggccaaccagccactgtgcctgccggccctgctcatctac
acggaggcctccgactacatccctgacgaccaccaggactacgcagaggccctgatcaat
ccgattaagcacgtcagcctgatggaccagagggccaagcagctggctgccctcattggc
gagagggaggctcaggctggcccggagacatgccaggagacccagtgtcagcagcagggc
tcccagctgaccccaaaccccacacccagcccactagacacctctccccgccggccccca
ggccctgtcacctcccccaccagcccttcccttagcagcccaggtcagcgggatgatctc
attgccagtatcctgtcagaggtggttgtggccccgttggacgagcttcgaggccacaag
gctctggtgaagctccggagccggcaagagcgggacctgagggagctgcacaagaagcat
cagcgcaaggcatttgctctcactcgccggttactggacagcttggctcaggcccaggcg
gagaacaggtgccggcatcggccaggagtcctaggcagggaggatgagagggaggaggag
gaggagatgaagcggtatcgagagttccagaagcgacaggtgcagagtctgctggagctg
cgggaggcccaggcggatgccgaagcggagcggaggatggagcacctgagacaggctctg
cagcggctcagggagattgtcctggatgctcacacgactcaggtcaagaggctgaaggag
atgaacgacagggagaagaaggagctgcagaagatcctggataggaaacgccacaatagt
atctcggaggccaagacaagggagaaacataagaaggaggcggaactgacagagattaac
cgtcgccatatcactgagtcggtcaactctatccgtcggctggaggaggcccagaagcag
cggcatgaacgcctcatggctgggcagcagcaggtcctacagcagctggtggaagaggaa
cccaagctgctggctcagctagcccaggaatgtcaggagcagcgggccaggctgccccag
gagatccgccggagcctgctgggcgagacgccggaggggctgggggacggacatctggtg
gcctgtgccagcaatggtcatgcgcctgggagcagtgggcacctatccggcgctgactcg
gagagccaagaggagaatacgaagctctga

DBGET integrated database retrieval system