Molossus molossus (Pallas's mastiff bat): 118633993
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Entry
118633993 CDS
T07221
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
mmf
Molossus molossus (Pallas's mastiff bat)
Pathway
mmf04140
Autophagy - animal
mmf04141
Protein processing in endoplasmic reticulum
mmf04210
Apoptosis
mmf04932
Non-alcoholic fatty liver disease
mmf05010
Alzheimer disease
mmf05012
Parkinson disease
mmf05014
Amyotrophic lateral sclerosis
mmf05016
Huntington disease
mmf05017
Spinocerebellar ataxia
mmf05022
Pathways of neurodegeneration - multiple diseases
mmf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
118633993 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118633993 (ERN1)
09143 Cell growth and death
04210 Apoptosis
118633993 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
118633993 (ERN1)
05012 Parkinson disease
118633993 (ERN1)
05014 Amyotrophic lateral sclerosis
118633993 (ERN1)
05016 Huntington disease
118633993 (ERN1)
05017 Spinocerebellar ataxia
118633993 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
118633993 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118633993 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
118633993 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmf01001
]
118633993 (ERN1)
Enzymes [BR:
mmf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
118633993 (ERN1)
Protein kinases [BR:
mmf01001
]
Serine/threonine kinases: Other
IRE family
118633993 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Motif
Other DBs
NCBI-GeneID:
118633993
NCBI-ProteinID:
XP_036124190
LinkDB
All DBs
Position
Unknown
AA seq
974 aa
AA seq
DB search
MPARRLLLLLALLLPGPRIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVIDLLTGEKQQTLSSTFADSLCPSASLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDVDDKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKV
IHTNVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFNPGLKGKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSREEVIHLVDQTSPNAPTAVSQ
DMEAKFAHAPAKPEAPMDSMLKDIATIILSTFLLLGWVAFIITYPMSMHEQRQLQHQQFQ
KELEKIQLLQQQQLPFHAPGDMAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSSS
ASKAGSPSLEQDDEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILP
ECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCTATLQEYVEQKDFAHLGL
EPIALLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPSAHGRIKAMISDFGLCKKLAVGRH
SFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQA
NILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQ
DVSDRIERESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRA
MRNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMELCSHERLFQPYYVH
LPPEPQPPVTPDTL
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgccagcccggcggctgctgctgctgctggcgctgctgctgcccggccccaggattttt
ggaagtcccagcacggtgacccttcctgaaaccttgttgtttgtgtcaaccctcgatgga
agtttgcatgctgtcagcaagaggacaggctcgatcaaatggactttaaaagaagatcca
gttctgcaggttccaacgcacgttgaagagcctgccttcctccccgatcccaatgacggc
agcctgtacacacttgggggcaagaacaatgaaggcctgacgaaacttcccttcaccatc
cctgagttggtccaggcatccccatgccgaagttcagatgggattctctacatgggtaaa
aagcaggacatttggtatgtcattgaccttttgaccggggagaagcagcagactttgtca
tcgacctttgcagatagtctctgcccttcagcctctcttctgtatcttgggagaacagaa
tacaccatcaccatgtacgacaccaaaacccgagagctgcggtggaacgccacctacttc
gactacgcggcctcgctgcccgaggacgacgtggacgacaagatgtcccattttgtgtcc
aatggcgacgggctggtggtgactgtggacagtgaatcaggtgacgtgctgtggatccaa
aactatgcttctcccgtggtggccttttatgtctggcagcgggaggggctgaggaaggtg
atacacaccaatgtcgccgtggagaccctgcgctacctgaccttcatgtccggggaggtg
gggcgcatcaccaagtggaagtaccccttccccaaggagacggaggccaagagcaagctg
acgcccaccctgtatgtcgggaaatactctactagcctctacgcctccccgtcaatggtc
cacgagggggtcgctgttgtgccccgaggcagcactctccctttgctggagggcccccag
actgatggtgtcaccattggggacaaaggggagtgtgtgatcacacccagcaccgaccta
aagtttaaccctgggctcaaagggaagaacaagctcaactacttgaggaactactggctt
ctgattgggcaccatgaaacaccgctgtccgcgtccaccaagatgctggagagattcccc
aacaatctgcccaagcaccgggagaatgtgattcctgccgactcggagaaaaagagccgt
gaggaagttatccacctggtggaccagacttctccaaatgcacccaccgccgtttctcag
gacatggaggcaaagtttgctcatgcccctgccaagcccgaggcccccatggactccatg
ctcaaggacatcgccaccatcatcctcagcaccttcctgctcctcggctgggtggccttc
atcatcacctaccccatgagcatgcacgagcagcggcagctccagcaccagcagttccag
aaggaactggagaaaatccagctcctgcaacagcagcagctacccttccatgcacctgga
gacatggctcaggacgctgagctcctggactcgtccggcttatactcggagagctcgggc
accagcagccccagcacgtcccccagagcctccaaccactcccttcactccagcagctct
gcctccaaggcgggcagcccctccctggagcaggatgacgaggatgaggaaaccagcatg
gtgatggttgggaaaatttcattctgccccaaggatgtcctgggccacggagcggagggc
acgattgtgtaccggggcatgttcgacaaccgtgacgtggccgtcaagaggatcctcccc
gagtgcttcagtttcgccgaccgcgaggtccagctgctgcgagaatctgacgagcacccg
aacgtgatccggtacttctgcacagagagggaccggcagttccagtacatcgccattgag
ctgtgcacggccacgctgcaggagtacgtggagcagaaggacttcgcccacctcggcctg
gagcccatcgccctgctgcagcagaccacctccggcctggcccacctgcactccctcaac
attgttcacagagacctgaagccgcacaacatcctcctctccatgcccagtgcccacggc
aggatcaaggccatgatctctgacttcggcctctgcaagaagctggccgtgggcaggcac
agcttcagccgccgttcgggggtgcccggcaccgaaggctggatcgctccggagatgctg
agcgaagactgcaaggagaaccccacctacacagtggacatcttctctgctggctgcgtc
ttttactacgtgatttctgagggcagccaccctttcggcaagtccctgcagcggcaggcc
aacatcctcctgggcgcctacagcctcgactgcttgcaccccgagaagcatgaagacgtc
atcgcccgggaactgatagagaagatgatcgcaatggatcctcagaagcgcccgtcagcg
aagcacgtgctgaaacaccccttcttctggagcctggagaagcagctgcagttcttccag
gacgtgagtgaccgaatcgaaagggaatccctggacggcccgatcgtgaagcagctggag
agaggcgggagagctgtggtgaagatggactggagggagaacatcaccgtccccctccag
acagatctgcgcaagttcagaacctacaaaggcggctccgtcagagatctcctccgagcc
atgagaaataagaagcaccactaccgggagctccccgcggaggtgcgggagaccctgggc
tccctccccgacgacttcgtgcgctacttcacgtcccgcttcccccacctcctctcacac
acctaccgggccatggagctgtgcagccacgagaggctcttccagccctactacgtccac
ctgcccccggagcctcagcccccagtgactccagacaccctctga
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integrated database retrieval system
