Molossus molossus (Pallas's mastiff bat): 118634051
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Entry
118634051 CDS
T07221
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mmf
Molossus molossus (Pallas's mastiff bat)
Pathway
mmf01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mmf00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
118634051 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mmf03032
]
118634051 (TOP2A)
03036 Chromosome and associated proteins [BR:
mmf03036
]
118634051 (TOP2A)
Enzymes [BR:
mmf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
118634051 (TOP2A)
DNA replication proteins [BR:
mmf03032
]
Eukaryotic type
DNA Topoisomerases
118634051 (TOP2A)
Chromosome and associated proteins [BR:
mmf03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
118634051 (TOP2A)
Centrosome formation proteins
Centriole proteins
118634051 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
118634051
NCBI-ProteinID:
XP_036124257
LinkDB
All DBs
Position
Unknown
AA seq
1529 aa
AA seq
DB search
MEVSPLQPVNENMQISKAKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDAGMNYREITFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFKPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVAKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
IQLNKKCSSVKHNRIKGIPKLDDANDAGGRNSTDCTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFDEWKN
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDVLR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPEEEENEESDNEKETEKSDAVTGPTFNYLLDMPLWYLTKEKKD
ELCRLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGRAKG
KKTQLAEVLPSPSGKRVIPRVTIEMKAEAEKKIKRKIKNENIEGSPQEDSVEPDGLKQRL
EKKQKREAGTKAKKQSTLPFKPIKKGKKRSPWSDSESDMSGNESDFDVPPREVEPRRAAT
KTKFTIDLDSDEDFSDVDNSEDEDASPVKTKIPPKRTNKDPKPQKSTTSVIDVDVDDAKD
EAKDNVPLSLSSPAADFPVEIEIVNPAPKKKVTVKKTAAKSQTSTSAAGAKKRAAPKGTK
KDPDLTSDAPQKPDPPKTKIRRKRKPSTSDDSDSNFEKMISKAVTSKKSKGEGDDFHVDL
DSAVAPRVKSGRAKKPIKYLEESDEDDLF
NT seq
4590 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccgctgcagcccgtgaacgaaaacatgcaaatcagcaaagcgaagaaa
aacgaggatgcgaagaaaaggctgtccattgaaaggatctatcagaagaaaacgcagctg
gaacatatcttgctccgcccggacacctacatcggctccgtggaactagtgacccagcaa
atgtgggtttacgatgaagatgctggcatgaactatagggaaatcacttttgttcctggc
ttgtacaaaatcttcgatgagattctagtcaatgctgcagacaacaaacaaagggaccct
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctcta
atctttggacagctcttaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctacggagccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggaga
gctggtgagatggaactcaagccctttaatggagaagattatacatgtattaccttcaag
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactaatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaagtctttctcaatggaaat
aagctgccagtgaaaggattccgtagctatgtggatatgtatttgaaggataaagtggat
gaaactggcaatccattgaaaattatccatgaacaagtaaaccacaggtgggaagtatgt
ttaacaatgagtgaaaaaggctttcaacaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtggctaaacttgttgatgtt
gtaaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgactttacaagtcaagagttttggatcaacatgtcaattaagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaagtttaaggctcag
atccagttaaacaagaagtgttcatctgtaaaacataacagaatcaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaactctactgactgtacacttattctaact
gaaggagactcagctaaaaccttagctgtttcaggccttggtgtggttgggagagacaaa
tatggggttttccctcttagaggaaaaatgctcaatgttcgagaagcttctcataaacag
ataatggaaaatgccgaaattaacaatatcataaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagactcactgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggctttctatagtcttcctgaatttgatgaatggaagaat
tctaccccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtatccaattcaaatat
tctggtcccgaagatgatgccgcaatcagtctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcatttcatggaggatagaagacaacggaagttacttggtctt
cctgaggattacttgtatgggcaaactaccacatatctgacatacaatgacttcataaac
aaggagcttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttatttacgtgtttcaaacgaaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtaccaggttgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagtcctttggctcgattgttatttccacca
aaagatgatcacacattaaagttcttatatgatgacaatcaacgtgtggagcctgaatgg
tacattcctattatacccatggtgctgataaacggtgctgaaggaattggtactgggtgg
tcctgcaaaatccccaactttgatattcgtgaagttgtgaataacatcaggcgtttgatg
gatggagaagaacctttgccaatgctcccaagttataagaacttcaagggtactattgaa
gagctggctccaaatcagtatgtgattagtggtgaagtggctattctgaattccacaacc
attgaaatctcagaacttcccatcagaacatggacccagacatacaaagaacaggttcta
gaacccatgttgaatggcactgagaagacgcctcctctcataacagattatagggaatac
catacagacaccactgtgaagttcgttgtgaagatgactgaagaaaaactggcagaggct
gagagagctggactacacaaagtcttcaaactccaaactagtctcacatgtaactctatg
gtgctttttgaccatgtaggctgtttaaagaaatatgacacagtgcttgatgttctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaacaatcaggcacgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttttgattcagagg
ggatatgattctgatcctgtgaaggcttggaaagaagcccagcaaaaggttccagaggaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagtgatgctgtaactgga
ccaactttcaactaccttcttgatatgcctctttggtatctaaccaaagaaaagaaggat
gaactgtgcagactaagaaatgaaaaagagcaagaattggaaacattaaagagaaaaagt
ccatcagatttgtggaaagaagacttggccgcttttattgaagagctggaggctgttgaa
gccaaggaaaagcaagatgaacaagtaggacttcctgggaaaggggggagagcaaagggg
aaaaaaacacaattggctgaagttttgccttctccaagtggaaaaagagtcattccccga
gtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaggaaaattaagaatgaa
aatattgaaggaagccctcaagaggacagtgtggaaccagatggcctaaaacaaagatta
gagaagaaacagaaaagagaagcaggtaccaaggcaaagaaacaaagtacattgccattt
aaaccaatcaaaaaaggaaagaagagaagcccttggtctgattcggaatcagatatgagc
ggtaatgaaagtgattttgatgtccctccacgggaagtagaaccacgaagagcagcaaca
aaaaccaaattcacaatagatttggattcagatgaggatttctcagatgttgataacagt
gaagatgaagatgccagtccagtgaagaccaaaattcccccaaaacgtacaaacaaggac
ccgaagccacagaagagcaccacgtcagtcatagatgttgatgtcgatgatgccaaggat
gaagccaaggacaatgtaccgctttccctgagctcacctgctgctgacttcccagttgaa
atagaaatcgtgaaccctgctcctaaaaagaaagtgacagtgaagaagacagcggcaaaa
agtcagacttccacctctgctgcaggtgccaaaaaaagggctgcaccaaaaggaaccaaa
aaggatccagacttgacttctgatgcccctcaaaagcctgatccccccaaaaccaagatt
cgccgcaaaaggaagccatccacttctgatgattccgactctaattttgagaaaatgatt
tctaaagcagtcacaagcaagaaatccaagggagagggtgacgacttccacgtggactta
gactcagctgtggctcctcgggtaaagtctggccgggcaaagaagccgatcaagtacctt
gaagaatcagatgaagatgacctgttttaa
DBGET
integrated database retrieval system
