KEGG   Molossus molossus (Pallas's mastiff bat): 118634140
Entry
118634140         CDS       T07221                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mmf  Molossus molossus (Pallas's mastiff bat)
Pathway
mmf04010  MAPK signaling pathway
mmf04015  Rap1 signaling pathway
mmf04218  Cellular senescence
mmf04380  Osteoclast differentiation
mmf04620  Toll-like receptor signaling pathway
mmf04664  Fc epsilon RI signaling pathway
mmf04668  TNF signaling pathway
mmf04750  Inflammatory mediator regulation of TRP channels
mmf04912  GnRH signaling pathway
mmf04935  Growth hormone synthesis, secretion and action
mmf04936  Alcoholic liver disease
mmf05014  Amyotrophic lateral sclerosis
mmf05022  Pathways of neurodegeneration - multiple diseases
mmf05132  Salmonella infection
mmf05135  Yersinia infection
mmf05145  Toxoplasmosis
mmf05161  Hepatitis B
mmf05163  Human cytomegalovirus infection
mmf05167  Kaposi sarcoma-associated herpesvirus infection
mmf05169  Epstein-Barr virus infection
mmf05170  Human immunodeficiency virus 1 infection
mmf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmf05417  Lipid and atherosclerosis
mmf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118634140 (MAP2K6)
   04015 Rap1 signaling pathway
    118634140 (MAP2K6)
   04668 TNF signaling pathway
    118634140 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    118634140 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    118634140 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    118634140 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118634140 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    118634140 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118634140 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118634140 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118634140 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118634140 (MAP2K6)
   05161 Hepatitis B
    118634140 (MAP2K6)
   05163 Human cytomegalovirus infection
    118634140 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118634140 (MAP2K6)
   05169 Epstein-Barr virus infection
    118634140 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118634140 (MAP2K6)
   05135 Yersinia infection
    118634140 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118634140 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118634140 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    118634140 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118634140 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    118634140 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118634140 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmf01001]
    118634140 (MAP2K6)
Enzymes [BR:mmf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     118634140 (MAP2K6)
Protein kinases [BR:mmf01001]
 Serine/threonine kinases: STE group
  STE7 family
   118634140 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 118634140
NCBI-ProteinID: XP_036124348
LinkDB
Position
Unknown
AA seq 334 aa
MSQPKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDMEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLIIGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagccgaaaggcaagaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagatttagactccaaagcttgcatttct
attggaaaccagaactttgaggtgaaggcggatgacatggagcctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggca
gtgaagcgtatccgggccacagtaaatagccaggaacagaaaaggctactgatggatttg
gatgtttccatgaggacagtggactgtcctttcacggtcaccttttacggcgcactcttc
cgggagggtgacgtctggatctgcatggagctcatggatacgtcgctagataaattctac
aagcaagtgattgataaaggccaaacaattccagaagacatcttaggaaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaacgctctgggccaagtgaagatgtgcgacttcggcatc
agcggctatcttgtagactcggttgctaagaccatcgatgcaggatgcaaaccgtacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagcgtgaagtctgacatt
tggagtctgggcatcacaatgatcgagctggccatcctccggtttccctacgattcctgg
ggaactccttttcagcagctcaaacaggtggtggaggagccgtcgccgcagctcccagca
gacaagttctcggaagagtttgtcgactttacctcgcagtgcttgaagaagaattccaaa
gaacggccaacatatcccgagcttatgcaacatccatttttcaccctacatgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattattggagactaa

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