Molossus molossus (Pallas's mastiff bat): 118640912
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Entry
118640912 CDS
T07221
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
mmf
Molossus molossus (Pallas's mastiff bat)
Pathway
mmf00230
Purine metabolism
mmf01100
Metabolic pathways
mmf04927
Cortisol synthesis and secretion
mmf04934
Cushing syndrome
mmf05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mmf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118640912 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
118640912 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
118640912 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
118640912 (PDE8A)
Enzymes [BR:
mmf01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
118640912 (PDE8A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF5894
SPO22
VPS38
Response_reg
Motif
Other DBs
NCBI-GeneID:
118640912
NCBI-ProteinID:
XP_036133873
LinkDB
All DBs
Position
Unknown
AA seq
756 aa
AA seq
DB search
MRFHPDQLQVLLVFTKEDNQCNGFCKACEKAGFKCTVTKESQAVLACFLATHHDIIIIDH
RNPRNLDAEALCRSIRSSKFSENTVIIGVVRRRDKEDSSVMPLIAAGFTRRYVENPNLMA
CYNELLQLEFGEVRSQLKLRACNPVFTAVEKSQEAVEIISDTNLIQYANPAFESTMGYAS
GELIGKDLGEVPIHEKKAELLDTINSCIKLGKEWHGIYYAKNGDNVQQSVKIIPVIGQGG
KIRHYVSIIRVCNDKAEKITECVQCDTHTDNQSGKHKDNRKSSLDVRTVSSRTSEVSSQR
RHSSMARIHSMTIEAPINKVINIINAAQENGPVSVTEALDRVLEILRTSELYSPQFGAKD
DDPHGSDLVGGLMSDGLRRLSGNEHALSTKNLQVPSNAATPISLHDVPLQIAQAMEHEDY
WDFDIFELEAATQKRPLIYLGLKIFARFGICEFLNCSETTLRSWLQIIEAHYHSSNPYHN
STHAADVLHATAYFLCRERVKQTLDSVDEAAALIAATIHDVDHPGRTSAFLCNAGSELAI
LYNDIAVLESHHAALAFQLTTGDDKCNIFKHMARNDYWTLRHTIIDMVLATEMTKHFEHV
NKFINSVNKPLAELEENMVTDKDQAAINTVLRTPENRTLIKRMLIKCADVSNPCRPLEQC
IEWAARISEEYFSQTEEEKQRDLPVVMPAFDRKTCSIPKAQISFMDYFITGMFDAWDAFV
NLPELLQHLDNNFKYWEGLDKMKLRSLRPPPPPEPK
NT seq
2271 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatccagatcaactccaggtacttttagtgtttaccaaagaagataaccag
tgtaacgggttctgtaaggcatgtgaaaaagcagggtttaaatgtacagttaccaaggag
tctcaggctgtccttgcctgtttcctggccacacaccacgacatcatcatcatagaccac
agaaatccccgaaatctggatgcagaggcgctgtgcaggtctattagatcatcaaaattc
tcagaaaacacagttattattggtgtagtacgcaggagggataaagaagactcgtcagta
atgcccctcattgctgctggctttacgaggaggtatgtggaaaaccctaacctcatggcc
tgttacaatgagctgctccagctggagtttggagaggtgcggtcacagctgaaactcagg
gcttgtaacccagtattcactgcagtggagaaaagtcaagaagccgttgaaattataagt
gacaccaacctgatacagtacgcaaaccctgcatttgagtcaacaatgggctatgcatca
ggtgaactaatagggaaggacttaggagaagtgcctatacatgaaaaaaaggctgagctg
ctcgatactataaattcatgcatcaagttgggcaaggagtggcacggaatttactacgcc
aaaaatggagataatgtgcaacaaagtgtgaagataatacctgtcattggacagggagga
aaaattagacactatgtatccattatcagagtgtgcaacgataaggctgagaaaataact
gaatgtgttcagtgtgacactcacacagataatcagtcaggcaaacataaagacaacaga
aaaagttcgctagatgtcagaactgtttcctctcgaacaagtgaagtgtctagccagaga
cgacactcctccatggcccggatacattctatgaccattgaggcgcccatcaacaaggtg
atcaatatcatcaacgctgcccaggaaaacggccccgtttccgtgacagaagccttagac
cgtgtgctggagattctaagaacctccgaattatactcaccacagttcggtgctaaggat
gatgatcctcacggcagtgacctcgttgggggcctgatgtctgatggtttgcgaagacta
tctgggaatgaacatgctctttcaacaaaaaaccttcaagttccgagcaatgcagccacc
cccatatcccttcacgacgtcccactgcagatagctcaggccatggaacacgaggactac
tgggactttgacatttttgagctggaggcagccactcagaagaggcctttaatttatctc
ggtctcaaaatctttgctcgctttggaatctgtgaattcttaaactgctccgaaacaaca
ctgagatcatggttacaaattattgaagcccattaccattcttctaacccctaccacaat
tctacgcatgctgccgacgtgcttcacgccactgcctacttcctctgcagagaaagggta
aagcaaactttagattccgtcgacgaggccgctgccctcattgcagccacgatccatgac
gtggaccaccccgggaggaccagcgccttcctgtgcaacgccgggagcgagctggccatc
ctgtacaacgacatcgccgtgctggagagccaccacgccgccttggccttccagctcacc
actggcgatgacaagtgcaacatcttcaagcacatggccaggaatgactactggacactg
cgccacactattattgacatggtcttggctacagagatgacaaagcacttcgagcatgtc
aacaagtttatcaacagcgtcaacaagcctttggcagaactagaagaaaatatggtaact
gacaaagaccaagcagccataaacactgtgctcaggactccggagaaccgaactctgatc
aaacgaatgctgattaagtgtgctgatgtgtccaatccctgcagacccttggagcagtgt
attgagtgggccgcacgcatctcagaagaatatttttctcagaccgaggaagagaagcag
cgggacctgccggtggtgatgccggcctttgacagaaagacctgcagcatccccaaggcc
cagatctccttcatggactacttcatcacaggcatgttcgatgcttgggacgcctttgtc
aacctgccagagttactgcagcatctggacaacaacttcaaatactgggaaggactcgac
aagatgaagctgcggagcctccgaccacctccacccccggaaccaaaatag
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