KEGG   Molossus molossus (Pallas's mastiff bat): 118641186
Entry
118641186         CDS       T07221                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mmf  Molossus molossus (Pallas's mastiff bat)
Pathway
mmf01522  Endocrine resistance
mmf04010  MAPK signaling pathway
mmf04015  Rap1 signaling pathway
mmf04068  FoxO signaling pathway
mmf04071  Sphingolipid signaling pathway
mmf04114  Oocyte meiosis
mmf04148  Efferocytosis
mmf04218  Cellular senescence
mmf04261  Adrenergic signaling in cardiomyocytes
mmf04370  VEGF signaling pathway
mmf04380  Osteoclast differentiation
mmf04550  Signaling pathways regulating pluripotency of stem cells
mmf04611  Platelet activation
mmf04613  Neutrophil extracellular trap formation
mmf04620  Toll-like receptor signaling pathway
mmf04621  NOD-like receptor signaling pathway
mmf04622  RIG-I-like receptor signaling pathway
mmf04625  C-type lectin receptor signaling pathway
mmf04657  IL-17 signaling pathway
mmf04658  Th1 and Th2 cell differentiation
mmf04659  Th17 cell differentiation
mmf04660  T cell receptor signaling pathway
mmf04664  Fc epsilon RI signaling pathway
mmf04668  TNF signaling pathway
mmf04670  Leukocyte transendothelial migration
mmf04714  Thermogenesis
mmf04722  Neurotrophin signaling pathway
mmf04723  Retrograde endocannabinoid signaling
mmf04728  Dopaminergic synapse
mmf04750  Inflammatory mediator regulation of TRP channels
mmf04912  GnRH signaling pathway
mmf04914  Progesterone-mediated oocyte maturation
mmf04917  Prolactin signaling pathway
mmf04926  Relaxin signaling pathway
mmf04932  Non-alcoholic fatty liver disease
mmf04933  AGE-RAGE signaling pathway in diabetic complications
mmf04935  Growth hormone synthesis, secretion and action
mmf04936  Alcoholic liver disease
mmf05014  Amyotrophic lateral sclerosis
mmf05020  Prion disease
mmf05022  Pathways of neurodegeneration - multiple diseases
mmf05132  Salmonella infection
mmf05133  Pertussis
mmf05135  Yersinia infection
mmf05140  Leishmaniasis
mmf05142  Chagas disease
mmf05145  Toxoplasmosis
mmf05152  Tuberculosis
mmf05161  Hepatitis B
mmf05163  Human cytomegalovirus infection
mmf05167  Kaposi sarcoma-associated herpesvirus infection
mmf05169  Epstein-Barr virus infection
mmf05170  Human immunodeficiency virus 1 infection
mmf05171  Coronavirus disease - COVID-19
mmf05205  Proteoglycans in cancer
mmf05208  Chemical carcinogenesis - reactive oxygen species
mmf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmf05415  Diabetic cardiomyopathy
mmf05417  Lipid and atherosclerosis
mmf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118641186 (MAPK12)
   04015 Rap1 signaling pathway
    118641186 (MAPK12)
   04370 VEGF signaling pathway
    118641186 (MAPK12)
   04668 TNF signaling pathway
    118641186 (MAPK12)
   04068 FoxO signaling pathway
    118641186 (MAPK12)
   04071 Sphingolipid signaling pathway
    118641186 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    118641186 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    118641186 (MAPK12)
   04218 Cellular senescence
    118641186 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    118641186 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118641186 (MAPK12)
   04613 Neutrophil extracellular trap formation
    118641186 (MAPK12)
   04620 Toll-like receptor signaling pathway
    118641186 (MAPK12)
   04621 NOD-like receptor signaling pathway
    118641186 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    118641186 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    118641186 (MAPK12)
   04660 T cell receptor signaling pathway
    118641186 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    118641186 (MAPK12)
   04659 Th17 cell differentiation
    118641186 (MAPK12)
   04657 IL-17 signaling pathway
    118641186 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    118641186 (MAPK12)
   04670 Leukocyte transendothelial migration
    118641186 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118641186 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    118641186 (MAPK12)
   04917 Prolactin signaling pathway
    118641186 (MAPK12)
   04926 Relaxin signaling pathway
    118641186 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    118641186 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118641186 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    118641186 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    118641186 (MAPK12)
   04722 Neurotrophin signaling pathway
    118641186 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118641186 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118641186 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    118641186 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    118641186 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    118641186 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118641186 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118641186 (MAPK12)
   05161 Hepatitis B
    118641186 (MAPK12)
   05171 Coronavirus disease - COVID-19
    118641186 (MAPK12)
   05163 Human cytomegalovirus infection
    118641186 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118641186 (MAPK12)
   05169 Epstein-Barr virus infection
    118641186 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118641186 (MAPK12)
   05135 Yersinia infection
    118641186 (MAPK12)
   05133 Pertussis
    118641186 (MAPK12)
   05152 Tuberculosis
    118641186 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118641186 (MAPK12)
   05140 Leishmaniasis
    118641186 (MAPK12)
   05142 Chagas disease
    118641186 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118641186 (MAPK12)
   05020 Prion disease
    118641186 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    118641186 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118641186 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    118641186 (MAPK12)
   05415 Diabetic cardiomyopathy
    118641186 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118641186 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    118641186 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118641186 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118641186 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmf01001]
    118641186 (MAPK12)
Enzymes [BR:mmf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     118641186 (MAPK12)
Protein kinases [BR:mmf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   118641186 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like UvrD_C Haspin_kinase
Other DBs
NCBI-GeneID: 118641186
NCBI-ProteinID: XP_036134175
LinkDB
Position
Unknown
AA seq 367 aa
MSSPPPARRGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGTKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLRGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSAGCIMAEMITGKILFKGNDHLDQLKEILK
VTGTPPDDFVQRLQSADAKNYMKGLPELEKKDFASILTNASPQAVNLLEKMLVLDAERRV
TAAEALTHPYFESLHEAEDEPKAQKYDESFDDVDRTLDEWKRDTYKEVLSFKPPRQLGAK
ASKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgccgcccgcccgcaggggcttttaccgccaggaggtgaccaagaccgcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctcgggcgcctatggcgcc
gtgtgctccgccgtggacagccgcacaggcaccaaagtggccatcaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgggagctgcgcctcctgaagcac
atgcgccacgagaacgtgattgggctgctggacgtgttcaccccagatgaaagcctggat
gatttcacagacttttacctggtcatgccgttcatgggcaccgacctgggcaagctcatg
aagcatgagaagctgagcgaggaccgaatccagtttctcgtctaccagatgctgagaggg
ctgaagtatatccacgctgctggcgtcattcatagggacctgaagcctggcaacctggca
gtaaatgaggactgtgagctgaagatcctggactttggcctggccaggcaggcagacagc
gagatgacggggtatgtagtgactcggtggtaccgggcacctgaggtcatcttgaactgg
atgcactacacacagacagtggacatctggtctgcgggctgcatcatggcagagatgatc
acagggaagatactgttcaagggcaacgaccacctggaccagctgaaggagatcttgaag
gtgacgggcacacctcccgatgattttgtacagaggctgcagagtgctgatgcaaagaac
tacatgaagggcctccccgagctggagaagaaggattttgcttccatcttgaccaatgca
agccctcaggctgtgaacctcctggagaaaatgctggtgctggatgcggagcggcgggtg
acggcggccgaggcgctgacccacccctacttcgagtcactgcatgaagcggaggacgag
cccaaggcccagaagtacgacgaatccttcgatgacgtggaccgcacactggacgagtgg
aagcgtgacacgtataaagaggtgctcagcttcaagcctccccggcagctgggggccaag
gcctccaaggagacggccctgtga

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