KEGG   Molossus molossus (Pallas's mastiff bat): 118642307
Entry
118642307         CDS       T07221                                 
Symbol
MAPK3
Name
(RefSeq) mitogen-activated protein kinase 3 isoform X1
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
mmf  Molossus molossus (Pallas's mastiff bat)
Pathway
mmf01521  EGFR tyrosine kinase inhibitor resistance
mmf01522  Endocrine resistance
mmf01524  Platinum drug resistance
mmf04010  MAPK signaling pathway
mmf04012  ErbB signaling pathway
mmf04014  Ras signaling pathway
mmf04015  Rap1 signaling pathway
mmf04022  cGMP-PKG signaling pathway
mmf04024  cAMP signaling pathway
mmf04062  Chemokine signaling pathway
mmf04066  HIF-1 signaling pathway
mmf04068  FoxO signaling pathway
mmf04071  Sphingolipid signaling pathway
mmf04072  Phospholipase D signaling pathway
mmf04114  Oocyte meiosis
mmf04140  Autophagy - animal
mmf04148  Efferocytosis
mmf04150  mTOR signaling pathway
mmf04151  PI3K-Akt signaling pathway
mmf04210  Apoptosis
mmf04218  Cellular senescence
mmf04261  Adrenergic signaling in cardiomyocytes
mmf04270  Vascular smooth muscle contraction
mmf04350  TGF-beta signaling pathway
mmf04360  Axon guidance
mmf04370  VEGF signaling pathway
mmf04371  Apelin signaling pathway
mmf04380  Osteoclast differentiation
mmf04510  Focal adhesion
mmf04520  Adherens junction
mmf04540  Gap junction
mmf04550  Signaling pathways regulating pluripotency of stem cells
mmf04611  Platelet activation
mmf04613  Neutrophil extracellular trap formation
mmf04620  Toll-like receptor signaling pathway
mmf04621  NOD-like receptor signaling pathway
mmf04625  C-type lectin receptor signaling pathway
mmf04650  Natural killer cell mediated cytotoxicity
mmf04657  IL-17 signaling pathway
mmf04658  Th1 and Th2 cell differentiation
mmf04659  Th17 cell differentiation
mmf04660  T cell receptor signaling pathway
mmf04662  B cell receptor signaling pathway
mmf04664  Fc epsilon RI signaling pathway
mmf04666  Fc gamma R-mediated phagocytosis
mmf04668  TNF signaling pathway
mmf04713  Circadian entrainment
mmf04720  Long-term potentiation
mmf04722  Neurotrophin signaling pathway
mmf04723  Retrograde endocannabinoid signaling
mmf04724  Glutamatergic synapse
mmf04725  Cholinergic synapse
mmf04726  Serotonergic synapse
mmf04730  Long-term depression
mmf04810  Regulation of actin cytoskeleton
mmf04910  Insulin signaling pathway
mmf04912  GnRH signaling pathway
mmf04914  Progesterone-mediated oocyte maturation
mmf04915  Estrogen signaling pathway
mmf04916  Melanogenesis
mmf04917  Prolactin signaling pathway
mmf04919  Thyroid hormone signaling pathway
mmf04921  Oxytocin signaling pathway
mmf04926  Relaxin signaling pathway
mmf04928  Parathyroid hormone synthesis, secretion and action
mmf04929  GnRH secretion
mmf04930  Type II diabetes mellitus
mmf04933  AGE-RAGE signaling pathway in diabetic complications
mmf04934  Cushing syndrome
mmf04935  Growth hormone synthesis, secretion and action
mmf04960  Aldosterone-regulated sodium reabsorption
mmf05010  Alzheimer disease
mmf05020  Prion disease
mmf05022  Pathways of neurodegeneration - multiple diseases
mmf05034  Alcoholism
mmf05132  Salmonella infection
mmf05133  Pertussis
mmf05135  Yersinia infection
mmf05140  Leishmaniasis
mmf05142  Chagas disease
mmf05145  Toxoplasmosis
mmf05152  Tuberculosis
mmf05160  Hepatitis C
mmf05161  Hepatitis B
mmf05163  Human cytomegalovirus infection
mmf05164  Influenza A
mmf05165  Human papillomavirus infection
mmf05166  Human T-cell leukemia virus 1 infection
mmf05167  Kaposi sarcoma-associated herpesvirus infection
mmf05170  Human immunodeficiency virus 1 infection
mmf05171  Coronavirus disease - COVID-19
mmf05200  Pathways in cancer
mmf05203  Viral carcinogenesis
mmf05205  Proteoglycans in cancer
mmf05206  MicroRNAs in cancer
mmf05207  Chemical carcinogenesis - receptor activation
mmf05208  Chemical carcinogenesis - reactive oxygen species
mmf05210  Colorectal cancer
mmf05211  Renal cell carcinoma
mmf05212  Pancreatic cancer
mmf05213  Endometrial cancer
mmf05214  Glioma
mmf05215  Prostate cancer
mmf05216  Thyroid cancer
mmf05218  Melanoma
mmf05219  Bladder cancer
mmf05220  Chronic myeloid leukemia
mmf05221  Acute myeloid leukemia
mmf05223  Non-small cell lung cancer
mmf05224  Breast cancer
mmf05225  Hepatocellular carcinoma
mmf05226  Gastric cancer
mmf05230  Central carbon metabolism in cancer
mmf05231  Choline metabolism in cancer
mmf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmf05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118642307 (MAPK3)
   04012 ErbB signaling pathway
    118642307 (MAPK3)
   04014 Ras signaling pathway
    118642307 (MAPK3)
   04015 Rap1 signaling pathway
    118642307 (MAPK3)
   04350 TGF-beta signaling pathway
    118642307 (MAPK3)
   04370 VEGF signaling pathway
    118642307 (MAPK3)
   04371 Apelin signaling pathway
    118642307 (MAPK3)
   04668 TNF signaling pathway
    118642307 (MAPK3)
   04066 HIF-1 signaling pathway
    118642307 (MAPK3)
   04068 FoxO signaling pathway
    118642307 (MAPK3)
   04072 Phospholipase D signaling pathway
    118642307 (MAPK3)
   04071 Sphingolipid signaling pathway
    118642307 (MAPK3)
   04024 cAMP signaling pathway
    118642307 (MAPK3)
   04022 cGMP-PKG signaling pathway
    118642307 (MAPK3)
   04151 PI3K-Akt signaling pathway
    118642307 (MAPK3)
   04150 mTOR signaling pathway
    118642307 (MAPK3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118642307 (MAPK3)
   04148 Efferocytosis
    118642307 (MAPK3)
  09143 Cell growth and death
   04114 Oocyte meiosis
    118642307 (MAPK3)
   04210 Apoptosis
    118642307 (MAPK3)
   04218 Cellular senescence
    118642307 (MAPK3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118642307 (MAPK3)
   04520 Adherens junction
    118642307 (MAPK3)
   04540 Gap junction
    118642307 (MAPK3)
   04550 Signaling pathways regulating pluripotency of stem cells
    118642307 (MAPK3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118642307 (MAPK3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118642307 (MAPK3)
   04613 Neutrophil extracellular trap formation
    118642307 (MAPK3)
   04620 Toll-like receptor signaling pathway
    118642307 (MAPK3)
   04621 NOD-like receptor signaling pathway
    118642307 (MAPK3)
   04625 C-type lectin receptor signaling pathway
    118642307 (MAPK3)
   04650 Natural killer cell mediated cytotoxicity
    118642307 (MAPK3)
   04660 T cell receptor signaling pathway
    118642307 (MAPK3)
   04658 Th1 and Th2 cell differentiation
    118642307 (MAPK3)
   04659 Th17 cell differentiation
    118642307 (MAPK3)
   04657 IL-17 signaling pathway
    118642307 (MAPK3)
   04662 B cell receptor signaling pathway
    118642307 (MAPK3)
   04664 Fc epsilon RI signaling pathway
    118642307 (MAPK3)
   04666 Fc gamma R-mediated phagocytosis
    118642307 (MAPK3)
   04062 Chemokine signaling pathway
    118642307 (MAPK3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118642307 (MAPK3)
   04929 GnRH secretion
    118642307 (MAPK3)
   04912 GnRH signaling pathway
    118642307 (MAPK3)
   04915 Estrogen signaling pathway
    118642307 (MAPK3)
   04914 Progesterone-mediated oocyte maturation
    118642307 (MAPK3)
   04917 Prolactin signaling pathway
    118642307 (MAPK3)
   04921 Oxytocin signaling pathway
    118642307 (MAPK3)
   04926 Relaxin signaling pathway
    118642307 (MAPK3)
   04935 Growth hormone synthesis, secretion and action
    118642307 (MAPK3)
   04919 Thyroid hormone signaling pathway
    118642307 (MAPK3)
   04928 Parathyroid hormone synthesis, secretion and action
    118642307 (MAPK3)
   04916 Melanogenesis
    118642307 (MAPK3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118642307 (MAPK3)
   04270 Vascular smooth muscle contraction
    118642307 (MAPK3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    118642307 (MAPK3)
  09156 Nervous system
   04724 Glutamatergic synapse
    118642307 (MAPK3)
   04725 Cholinergic synapse
    118642307 (MAPK3)
   04726 Serotonergic synapse
    118642307 (MAPK3)
   04720 Long-term potentiation
    118642307 (MAPK3)
   04730 Long-term depression
    118642307 (MAPK3)
   04723 Retrograde endocannabinoid signaling
    118642307 (MAPK3)
   04722 Neurotrophin signaling pathway
    118642307 (MAPK3)
  09158 Development and regeneration
   04360 Axon guidance
    118642307 (MAPK3)
   04380 Osteoclast differentiation
    118642307 (MAPK3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    118642307 (MAPK3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118642307 (MAPK3)
   05206 MicroRNAs in cancer
    118642307 (MAPK3)
   05205 Proteoglycans in cancer
    118642307 (MAPK3)
   05207 Chemical carcinogenesis - receptor activation
    118642307 (MAPK3)
   05208 Chemical carcinogenesis - reactive oxygen species
    118642307 (MAPK3)
   05203 Viral carcinogenesis
    118642307 (MAPK3)
   05230 Central carbon metabolism in cancer
    118642307 (MAPK3)
   05231 Choline metabolism in cancer
    118642307 (MAPK3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118642307 (MAPK3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118642307 (MAPK3)
   05212 Pancreatic cancer
    118642307 (MAPK3)
   05225 Hepatocellular carcinoma
    118642307 (MAPK3)
   05226 Gastric cancer
    118642307 (MAPK3)
   05214 Glioma
    118642307 (MAPK3)
   05216 Thyroid cancer
    118642307 (MAPK3)
   05221 Acute myeloid leukemia
    118642307 (MAPK3)
   05220 Chronic myeloid leukemia
    118642307 (MAPK3)
   05218 Melanoma
    118642307 (MAPK3)
   05211 Renal cell carcinoma
    118642307 (MAPK3)
   05219 Bladder cancer
    118642307 (MAPK3)
   05215 Prostate cancer
    118642307 (MAPK3)
   05213 Endometrial cancer
    118642307 (MAPK3)
   05224 Breast cancer
    118642307 (MAPK3)
   05223 Non-small cell lung cancer
    118642307 (MAPK3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118642307 (MAPK3)
   05170 Human immunodeficiency virus 1 infection
    118642307 (MAPK3)
   05161 Hepatitis B
    118642307 (MAPK3)
   05160 Hepatitis C
    118642307 (MAPK3)
   05171 Coronavirus disease - COVID-19
    118642307 (MAPK3)
   05164 Influenza A
    118642307 (MAPK3)
   05163 Human cytomegalovirus infection
    118642307 (MAPK3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118642307 (MAPK3)
   05165 Human papillomavirus infection
    118642307 (MAPK3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118642307 (MAPK3)
   05135 Yersinia infection
    118642307 (MAPK3)
   05133 Pertussis
    118642307 (MAPK3)
   05152 Tuberculosis
    118642307 (MAPK3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118642307 (MAPK3)
   05140 Leishmaniasis
    118642307 (MAPK3)
   05142 Chagas disease
    118642307 (MAPK3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118642307 (MAPK3)
   05020 Prion disease
    118642307 (MAPK3)
   05022 Pathways of neurodegeneration - multiple diseases
    118642307 (MAPK3)
  09165 Substance dependence
   05034 Alcoholism
    118642307 (MAPK3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118642307 (MAPK3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    118642307 (MAPK3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118642307 (MAPK3)
   04934 Cushing syndrome
    118642307 (MAPK3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118642307 (MAPK3)
   01524 Platinum drug resistance
    118642307 (MAPK3)
   01522 Endocrine resistance
    118642307 (MAPK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmf01001]
    118642307 (MAPK3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmf03036]
    118642307 (MAPK3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmf04147]
    118642307 (MAPK3)
Enzymes [BR:mmf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     118642307 (MAPK3)
Protein kinases [BR:mmf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   118642307 (MAPK3)
Chromosome and associated proteins [BR:mmf03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     118642307 (MAPK3)
Exosome [BR:mmf04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   118642307 (MAPK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase FTA2 Kdo
Other DBs
NCBI-GeneID: 118642307
NCBI-ProteinID: XP_036135897
LinkDB
Position
Unknown
AA seq 379 aa
MAAAAAQGGGGGEPRGADGVGLGVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLDAMRDVYI
VQDLMETDLYKLLKSQQLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERL
KELIFQETARFQPGVLEAT
NT seq 1140 nt   +upstreamnt  +downstreamnt
atggcggcggcggcggctcaggggggcgggggcggggagccccggggagccgatggggtc
ggcctgggggtccccggggaagtggaggtagtgaaggggcagccgttcgacgtgggcccg
cgctacacgcagctgcagtacatcggcgagggcgcttatggcatggtcagctcagcttat
gatcacgtacgcaagacacgtgtggccatcaagaaaatcagccccttcgagcatcagacc
tactgccagcgcacacttcgggaaatccagatcttgctgcgcttccgccatgagaatgtc
attggcatccgagacattcttcgggcacctaccctggatgctatgagggatgtctacatt
gtgcaggacctgatggagacagacctgtataagttgctcaaaagccagcagctgagcaac
gaccacgtctgctacttcctctaccagatcctgcgaggcctcaagtatatccactcagcc
aacgtgctccaccgggatttaaagccctccaacctgctcatcaacaccacctgcgacctt
aagatctgtgattttggcctggcccggatcgctgatcctgagcatgaccacactggcttc
ctgacagaatacgtggccacacgctggtaccgggccccagagatcatgcttaactccaag
ggctacaccaagtccatcgacatctggtctgtgggctgcattctggctgagatgctctcc
aatcggcccatcttccctggcaagcactacctggaccagctcaaccacattctgggtatc
ctgggctccccatcccaggaggacctgaattgtatcatcaacatgaaggcccgaaactac
ctacagtctctgccttccaagaccaaggtggcctgggctaagctatttcccaagtcagac
tccaaagcccttgacctgctggatcggatgttgacctttaaccccaataaacggatcaca
gtagaagaagccctggctcacccctacctggagcagtactacgacccaacagatgagcca
gtggccgaggaacctttcacctttgacatggagctggatgatctacccaaggagcggctg
aaggagctcatattccaggaaaccgcccgcttccagcctggggtgctggaggccacctaa

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