Molossus molossus (Pallas's mastiff bat): 118643514
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Entry
118643514 CDS
T07221
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mmf
Molossus molossus (Pallas's mastiff bat)
Pathway
mmf00310
Lysine degradation
mmf01100
Metabolic pathways
mmf05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mmf00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
118643514 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
118643514 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmf03036
]
118643514 (DOT1L)
Enzymes [BR:
mmf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
118643514 (DOT1L)
Chromosome and associated proteins [BR:
mmf03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
118643514 (DOT1L)
HMT complexes
Dot1-containing complex
118643514 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
TAF1D
HALZ
Motif
Other DBs
NCBI-GeneID:
118643514
NCBI-ProteinID:
XP_036137515
LinkDB
All DBs
Position
Unknown
AA seq
1538 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAASTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTAVSSPQDAYKSPHSPFYQLPPSVQRHPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAARQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDETVSLHLRGKGGLARELEAEPSRLHLELDCSKFSLPHFSNMSPELSMNGHAAGY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRPRLEKLSGLTLPDYTRLSPAKLV
LRRHLSQDHTVSGKISAGELHPRAEHAKENGLPYQSPGLANGIKLSPQDPRPSSPVVLQM
TGEKSSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPNRAEKVRST
PSPVPQTRESSSTLEKQMGANAHGAGSNAAGSKSLTLAPTGFSYAGSVAISGALAGSPAP
LAPGVEPPAFDESSSSGSHFTTVGSRSSTPQHPQLLGQPWNSGPASPAHQLCVSPRLSTA
QGPLPDASKGDLPSEAGFSDPESEAKRRIIFTISAGAGSAKQSPSNKHSPLPGGVRGDSS
QSHGQDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQ
PLEITAISSPESSLKSSPVPYQDNDQPPILKKEKPLSQTNGAHYSPLTSDEEPGSEDEQG
SARIERKIATISLESKSPPKTLENGGSLVGRKPMPSSEPINSSKWKSTFSPIADLSLAKA
ADSPLQASSTLSQNSLFTFRPALEELGSVDAKLATHPRKSFPGALSGAGGVSPISNPPNG
FAFSGSLAADLSLHSFSDGASLSHKAPEVASLGAPLSFSAPRGKEGSVEPSPFVNKRQLD
GLGGLKGEGVKGREAEVSLPVCTPSDKASSHGKGGKGRDREPDFKNGHNLFISAAAVPPG
GLLSGPGLTTAASSASGTAPSSQTHRPFLGTFAPGPQFTLGPMSLQANLGPSVLQSLFNS
VPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGN
NT seq
4617 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccatgatgctgctcatgaaatcattgagacc
atccgatgggtctgtgaggaaatcccagacctcaagctcgctatggagaattacgtccta
atcgactatgacaccaaaagcttcgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggaaccacacagcccatgaagctgaacaca
cggccatccaatgggctcctgcggcacatcctgcagcaggtttacaaccactcggtgacg
gaccctgagaagctcaacaactacgagcccttctctccagaggtgtatggggagacctcc
tttgacctggtcgcgcagatgattgatgagatcaagatgactgaggatgacctgtttgtg
gacctgggaagtggagtgggccaggtcgtgctgcaggtcgccgcggccaccaactgcaaa
catcactacggagtcgagaaagccgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggcgatttcctctcagaggagtggagagaacggatcgctaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctacacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccgaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgagaaaataagagtaatacgaccacccccacgaaggtgccc
gagagcaaggctgctgtgcctgcagacacctctgtggattctggtgctgaagaagagaaa
gccgcgtcgaccgctatcaagaagccatccccctccaaagctcggaagaagaagctgaat
aagaagggccggaagctagctggccggaagcgtggacgtcccaagaagatgagcactgcg
aaccctgagcgtaagcccaagaagaaccctactgcactggacctgctacacgcccagact
gtgtcccagacggcggtgtcctcaccacaagatgcatacaagtcacctcacagcccattt
tatcagctacctcccagtgtgcagcggcacccccctgaccagctattgctggcacccacc
ccacctgcactgcagaagctgctagagtccttcaagattcagtacctgcagttcctggcg
tacacgaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaatgcccggttactgggtgccgcacggcagctgttcggtcactgccaggcccagaaa
gaagaaataaagaggctcttccagcagaaactggatgagttgggagtgaaggcgctgacc
tacagtgacctgatccaagcacagaaagagatctcagctcacaaccagcagctgcgagag
cagacagagcagctagagaaggacaacagggagctgagaagccagagcctgcagctgctg
aaggctcggtgtgaggaattgaagttggactggtctacactgtccctggagaacctgctg
aaggagaagcaggccctgaagagccaaatctccgagaaacagaggcactgcctggagctt
cagatcagcattgtggagctggaaaagagccagcggcagcaggagctcctgcagctcaag
tcatgcgtgccacctgatgagaccgtgtccctgcatctgcgagggaaaggtggcctggcc
cgggaactggaggcagagcccagccggctgcatctcgagctggactgctccaagttctca
ctgccccacttcagtaacatgagcccagagctctccatgaatggccacgcagctggctat
gagctctgcaacacgctgagccggccctcgtccaagcagaacaccccccagtacctggcc
tccccactagaccaggaggttgtgccatgtacccccagccacagcagccggccccggctt
gagaagctgtctggcttgaccttgccagactacaccaggctctccccggccaagctggtg
ctgagacgccacctgagccaggaccacacagtcagtggcaagatatctgctggcgagctg
cacccaagagctgagcacgccaaggagaatggccttccataccagagcccgggccttgcc
aatggcatcaagctgagccctcaggatccacggccctcatcccctgtggttttacagatg
acaggagaaaaaagcagtgagaagggtctgaaggagcgtgcctacgccagcagtggggag
gctatcaccagcctacccgtcagcatcccgctcagcactgtgcagcccagcaagcttcct
gttagcatccctctggccagcgtggtgttgcccaaccgtgctgagaaggtgagaagcacc
cccagccctgtgcctcagacccgagagtcctcgtccacacttgaaaagcagatgggtgct
aatgcccatggtgctgggagcaacgctgctgggagcaaaagcctcactttggcgcccaca
ggcttctcctacgctggctcagtggccatcagcggggccctggcaggcagcccagcccca
cttgctcctggagttgagccccctgccttcgatgagtcctccagctcggggagccacttc
accaccgtgggttcccgaagctctaccccgcaacaccctcaactgctggggcagccctgg
aactctggtcctgcctcacccgctcaccagctctgtgtcagcccccggctcagcactgcc
cagggcccactccctgatgccagcaaaggggaccttccctctgaggctggcttctccgat
ccagagagcgaggccaagagaaggatcatcttcaccatctcagctggtgctggcagtgcc
aagcagtcaccttccaacaagcacagccctctgcccgggggtgtccgcggagacagcagt
cagagccacgggcaagacagccgaaagcggggcaggaggaagcgggcatctgcagggacc
cctagcctaagctctggcgtgtcacccaagcgccgggccttgccatctgtcgccggcctc
ttcactcagtcttcagggtctccgctcaacctgaactccatggtcaacaacattaaccag
cctttggaaatcacagccatctcgtcccctgagagctccctgaagagctcccctgtacct
taccaggacaatgaccagccacccatactcaagaaagagaagcctctgagccagaccaat
ggggcccactactccccgctgacctcagatgaggagccaggttctgaggacgagcaaggc
agcgccagaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccaaaa
accttggaaaacggtggtagcctggtaggaaggaagccgatgccctccagcgagcccatc
aacagcagcaagtggaagtccaccttctcgcccattgccgacctcagcctggccaaggct
gctgacagcccactacaggccagctccactctgagccagaactccctgttcactttccgg
cccgccctagaggagctcggctcagttgatgccaagctggctactcaccccaggaagagc
tttccgggtgcactgtcgggggccggcggggtgagccccatcagcaaccctcccaatggc
tttgccttcagcgggagcctggctgccgacctcagtttacacagtttcagtgatggtgct
tctctctctcacaaggcccctgaagtggccagcctgggtgcccccctgagcttttctgcc
ccaaggggtaaggagggcagcgtggaacccagcccctttgtgaacaagaggcagctggat
ggactgggtggcctgaagggcgagggagtcaagggcagggaagcagaggttagcctgccc
gtgtgcacgccctcagacaaggcctcgtcgcatggcaaggggggcaagggccgggaccgc
gagcctgacttcaaaaacggccacaatctcttcatttctgctgctgctgtgcctcctggg
ggcctcctcagcggtccaggcctcaccacagcagcatcctcggcaagcggcacagcccct
tcctcccagacacaccggcccttcctgggtactttcgcacctggcccacagttcaccttg
ggccccatgtccctgcaggccaacttaggcccgtctgtgctgcaatccttgttcaactct
gtgccagctgccgctggcctagtgcatgtctcatccgccgcaaccagactgaccaactca
cacgccatgggcagcttttcctccggtgtggcaggtggcgcagttggaggtaactag
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integrated database retrieval system
