Mycobacterium marinum M: MMAR_1726
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Entry
MMAR_1726 CDS
T00694
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase (large subunit) LeuC
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mmi
Mycobacterium marinum M
Pathway
mmi00290
Valine, leucine and isoleucine biosynthesis
mmi00660
C5-Branched dibasic acid metabolism
mmi01100
Metabolic pathways
mmi01110
Biosynthesis of secondary metabolites
mmi01210
2-Oxocarboxylic acid metabolism
mmi01230
Biosynthesis of amino acids
Module
mmi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MMAR_1726 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MMAR_1726 (leuC)
Enzymes [BR:
mmi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MMAR_1726 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MMAR_1726 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
ACC40175
UniProt:
B2HII1
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Position
2078579..2080000
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AA seq
473 aa
AA seq
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MALQTREARTLAEKVWDDHVVVSGRNEAPDLIYIDLHLVHEVTSPQAFDGLRLAGRPVRR
PDLTIATEDHNVPTVDIDKPIADPVSRTQVETLRRNCAEFGIRLHPMGDVEQGIVHVVGP
QLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGR
LPAGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMV
APDETTYEYLRNRPHAPTGAQWDAALGYWQQLRTDPGAVFDTEVHLDAAELSPFVTWGTN
PGQGVPLCATVPDPELIGDDGERQAAEKALAYMDLEPGKAMRDIAVDAVFVGSCTNGRIE
DLRVVAEVLRGRKVAPGVRMLIVPGSMRVRAQAEKEGLGEVFTVAGAEWRQAGCSMCLGM
NPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSAPADLN
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atggcactgcagacgcgcgaggcgcgcacgctggctgagaaggtctgggacgaccacgtc
gtggtgtccggtcggaacgaggctcccgacctgatctacatcgatctgcatctggtgcat
gaggtcaccagcccgcaggcattcgatggtctgcgcctggccggccgcccggtgcgacgg
cccgatctgaccatcgccaccgaggatcacaatgtgccgaccgtcgatatcgataagccg
atcgccgatccggtgtctcggacccaggtggagacattgcggcgtaattgcgcggaattc
ggcatccggctgcaccccatgggtgatgtcgagcagggcatcgtgcacgtcgtgggacct
cagttgggcctcactcagccgggaatgaccatcgtctgtggtgacagccacacttcgacc
catggcgcgttcggtgcattggcgatgggcatcggcacttccgaagtcgagcatgtgctc
gcaacacagacgctgccgttgcggccgttcaagacgatggcggtcaatgtggatgggcga
ctacccgcaggagtgtcggccaaggacatcatccttgcgctgatcgccaagatcggcacc
ggcggtgggcaggggcacgtcatcgaataccggggcagcgccattgaatcgctgtccatg
gaaggccggatgacgatctgcaacatgagcattgaggccggcgcccgagccgggatggtg
gcgccggacgagaccacttacgagtacttgcgaaaccggccacacgccccaaccggtgcc
cagtgggatgccgcgctcgggtactggcaacaactgcggaccgatcctggcgccgtcttc
gacaccgaggtccatctcgacgccgccgagctgagcccctttgttacgtggggaaccaat
cccggccagggcgtgccgctttgcgccacggtgcccgatcccgagctcatcggcgatgac
ggcgagcgccaggccgccgagaaagcattggcgtacatggaccttgagccaggaaaagcc
atgcgcgatatcgcggtcgatgccgtgttcgtcgggtcgtgcaccaacggccggatcgag
gatctgcgggtcgtggccgaagtgctgcgtggccgcaaggtcgccccaggggtgcgaatg
ctcatcgttcccggctccatgcgggtgcgtgcccaggccgagaaggagggcctgggtgag
gtcttcacggtcgcgggcgccgaatggcggcaggcgggatgctctatgtgcctagggatg
aaccccgatcagctcgcgccgggggagcgctgtgcggcgacgtccaaccgcaacttcgag
gggcgccagggcaagggcgggcggacacatttggtctcgccggcggtggccgccgcaacc
gcggttcgcggcaccctatccgcgcctgccgatttgaattga
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