KEGG   Mycobacterium tuberculosis variant microti: RN08_0636
Entry
RN08_0636         CDS       T04291                                 
Name
(GenBank) vitamin B12-dependent ribonucleoside-diphosphate reductase
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
mmic  Mycobacterium tuberculosis variant microti
Pathway
mmic00230  Purine metabolism
mmic00240  Pyrimidine metabolism
mmic01100  Metabolic pathways
mmic01232  Nucleotide metabolism
Module
mmic_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
mmic_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mmic00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    RN08_0636
   00240 Pyrimidine metabolism
    RN08_0636
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mmic03400]
    RN08_0636
Enzymes [BR:mmic01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     RN08_0636
DNA repair and recombination proteins [BR:mmic03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    RN08_0636
SSDB
Motif
Pfam: Ribonuc_red_lgC Ribonuc_red_lgN ATP-cone RNR-II_ins_dom
Other DBs
NCBI-ProteinID: AMC58063
LinkDB
Position
663229..664896
AA seq 555 aa
MPFDIARIEAAVTRAAREVACDDPDMPGTVAKAVADALGRGIAPVEDIQDCVEARLGEAG
LDDVARVYIIYRQRRAELRTAKALLGVRDELKLSLAAVTVLRERYLLHDEQGRPAESTGE
LMDRSARCVAAAEDQYEPGSSRRWAERFATLLRNLEFLPNSPTLMNSGTDLGLLAGCFVL
PIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVASTGGTASGPVSFLRLYDSA
AGVVSMGGRRRGACMAVLDVSHPDICDFVTAKAESPSELPHFNLSVGVTDAFLRAVERNG
LHRLVNPRTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTINRANPVPGRGRIEATNP
CGEVPLLPYESCNLGSINLARMLADGRVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGE
AARATRKIGLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERGAF
PAFTDSRFARSGPRRNAQVTSVAPTGTISLIAGTTAGIEPMFAIAFTRAIVGRHLLEVNP
CFDRLARDRAFIVTS
NT seq 1668 nt   +upstreamnt  +downstreamnt
gtgccgttcgacatcgcgcggatcgaagcagcggtgacgcgggcagcgcgcgaggtggct
tgcgacgaccccgatatgccgggcaccgtagcgaaagccgtcgccgacgcactcgggcgc
ggtatcgctcccgttgaggacattcaggactgcgtggaggcccggctgggggaagccggt
ctggatgacgtggcccgtgtttacatcatctaccggcagcggcgcgccgagctgcggacg
gctaaggccttgctcggcgtgcgggacgagttaaagctgagcttggcggccgtgacggta
ctgcgcgagcgctatctgctgcacgacgagcagggccggccggccgagtcgaccggcgag
ctgatggaccgatcggcgcgctgtgtcgcggcggccgaggaccagtatgagccgggctcg
tcgaggcggtgggccgagcggttcgccacgctattacgcaacctggaattcctgccgaat
tcgcccacgttgatgaactctggcaccgacctgggactgctcgccggctgttttgttctg
ccgattgaggattcgctgcaatcgatctttgcgacgctgggacaggccgccgagctgcag
cgggctggaggcggcaccggatatgcgttcagccacctgcgacccgccggggatcgggtg
gcctccacgggcggcacggccagcggaccggtgtcgtttctacggctgtatgacagtgcc
gcgggtgtggtctccatgggcggtcgccggcgtggcgcctgtatggctgtgcttgatgtg
tcgcacccggatatctgtgatttcgtcaccgccaaggccgaatcccccagcgagctcccg
catttcaacctatcggttggtgtgaccgacgcgttcctgcgggccgtcgaacgcaacggc
ctacaccggctggtcaatccgcgaaccggcaagatcgtcgcgcggatgcccgccgccgag
ctgttcgacgccatctgcaaagccgcgcacgccggtggcgatcccgggctggtgtttctc
gacacgatcaatagggcaaacccggtgccggggagaggccgcatcgaggcgaccaacccg
tgcggggaggtcccactgctgccttacgagtcatgtaatctcggctcgatcaacctcgcc
cggatgctcgccgacggtcgcgtcgactgggaccggctcgaggaggtcgccggtgtggcg
gtgcggttccttgatgacgtcatcgatgtcagccgctaccccttccccgaactgggtgag
gcggcccgcgccacccgcaagatcgggctgggagtcatgggtttggcggaactgcttgcc
gcactgggtattccgtacgacagtgaagaagccgtgcggttagccacccggctcatgcgt
cgcatacagcaggcggcgcacacggcatcgcggaggctggccgaagagcggggcgcattc
ccggcgttcaccgatagccggttcgcgcggtcgggcccgaggcgcaacgcacaggtcacc
tccgtcgctccgacgggcaccatctcactgatcgccggaaccaccgcgggcatcgagccg
atgttcgccatcgcgttcacccgcgccatcgtcggccggcatctgctggaggtcaatccg
tgcttcgaccgactggcccgcgatcgggcttttatcgtgacgagctga

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