KEGG   Mycobacterium tuberculosis variant microti: RN08_2639
Entry
RN08_2639         CDS       T04291                                 
Name
(GenBank) peptide synthetase
  KO
K04789  mycobactin peptide synthetase MbtE
Organism
mmic  Mycobacterium tuberculosis variant microti
Pathway
mmic01053  Biosynthesis of siderophore group nonribosomal peptides
Brite
KEGG Orthology (KO) [BR:mmic00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01053 Biosynthesis of siderophore group nonribosomal peptides
    RN08_2639
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:mmic01008]
    RN08_2639
Polyketide biosynthesis proteins [BR:mmic01008]
 Nonribosomal peptide synthetase (NRPS)
  Nonlinear NRPS
   Mycobactin synthetase
    RN08_2639
SSDB
Motif
Pfam: Condensation AMP-binding PP-binding AMP-binding_C
Other DBs
NCBI-ProteinID: AMC60066
LinkDB
Position
complement(2655934..2661129)
AA seq 1731 aa
MTNTADIGARLDEARLELLRRRLADRGLSSAAQDIGPHTDDRLSDGQARMWFVQMADPSG
ALLNICVSYRITGDIDLARLRDAVNAVARRHRILRTTYPVGDDGVAQPTVHADLRPGWTQ
YDLTDLSQRAQRLRLEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDD
GSWRVFFTDLTQAYSRADLGADLGPEHRPSAASGPDTTEADLNYWRAIMADPPEPLELPG
PAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLLAAFGALVHRYTHSDDFL
VAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRV
VRELNPDRRHGAERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRA
GVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLREVSRG
ERFDTPVKTLVDLVNEQTTRTPDATAVVYEGQHFTYHDLNEASNRLGHWLIEQGIGSEDR
VAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGY
RSDDPTDADRIRPLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYDVDDTDR
LLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGITAMHFVPSLLG
LFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALLHNFYGPTETVINASRFKVVG
PQGTRIVPIGRPKINTTMHLLDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVA
DPFNPGSRMYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAV
VVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIP
ITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGRDRVGADDSFFDLGGHS
LLATKLVAAVRNAFGVDVGVREIFEFATVTALAGHIDTLDSDSARPRLTRVDHDGPVRLS
SSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREIGGV
PHQIIQPPAEVPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRAALLSTPEQTVLSLV
VHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAGIVGP
QRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAAVSRDLGVTEFM
LLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGFFINIVVLRNDLRGNPTLREVL
QRTRQMALAAYAHQDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDGD
TTLRVLEPTFDAAQADLSVNFFACGDEYRGHVIYRTELYERATAQRFADWLVRVVEAFAD
RPDQPLREVEMVSAQARRRILDRSNAGAGTARVYLLDDALKPVPVGVVGDVYYGGGPAVG
ARLARPSETATRFVADPFAAQPGSRLYRNGERGVWKADGQLELLAEIERLPTAQAAPVPA
EPADTETERALAAILADVLEVGEVGRYDDFFNLGGDSILATQVAARARDGGIPLTARMVF
EHPVLCELAAAVDAKPHVEAEPDDKHHAPMSTSGLSPDELSALTASWDQWP
NT seq 5196 nt   +upstreamnt  +downstreamnt
gtgactaataccgccgacatcggcgcccgcctcgacgaggcccgattggagctgctgcgt
cgcaggctcgccgaccgcggcctgtcctcggctgcgcaggacattggcccgcacactgac
gatcggctctccgacggccaggcccggatgtggttcgtgcagatggccgaccccagcggt
gcgttactcaacatctgtgtgtcctaccgcatcaccggtgacatcgatctggccaggttg
cgcgacgcagtcaacgccgtcgcccgtcgccatcggatactgcgtaccacctaccctgtc
ggcgacgacggagtcgcccagccgaccgtgcacgcggatcttcgccccggctggacacaa
tacgacctgacggacctgtcccaacgcgcccagcggctgcgcctggaggtgttggctcag
cgcgaattctgcgctcccttcgagctttcccgcgacgcgccattgcgaatcacggtggtg
cgcacggctgccgacgaacacgtgctgctgttggtggcccaccacatcgcctgggatgat
ggttcgtggcgggtgttcttcaccgatctcacccaggcgtactcgcgagctgacctaggg
gccgatctggggccagaacaccgtccgtcggccgcatccggacccgacactaccgaggcc
gacctcaactattggcgcgcgatcatggccgatccgccagagccgctggaacttcccggc
ccagccggaacgtgtgtgccgaccagttggcgtgccgcgcgcgccacgttgcggctgccc
gccgacaccgctgcgcgggtggccacgatggcgaagaacaccggttgcactccctacatg
gtgctgctggccgcgttcggtgccctggtgcatcgctacacccacagtgacgacttcctc
gtggcggctccggtgctcaaccgtggcgccggaaccgaagatgccatcggctatttcggc
aacacggtagcgatgcggctgcgaccgcaatcggcgatgagtttccgggagttgctgacc
gccacccgcgacatcgccagcggggcgttcgcacaccaacggatcaacctcgaccgcgtg
gtaagggaactgaaccccgatcgccggcacggtgccgagcgcatgacccgggtcagcttc
ggtttccgggagcccgacggcggcggattcaacccgccaggcatcgagtgcgagcgctac
gacctgcgcagcaacatcacgcagctgccgttgggcttcatggtcgaattcgaccgcgcg
ggtgtgctggtcgaggccgaacacctggtggagatcctggaacccgccctggccaagcag
atgcttcgacacttcggtgtgctgctcgacaatgcgctggccgcccccgacaacacgttg
tcggggctggcgctgatggatgagcgcgacgccgccaggctgcgcgaggtgtcgcgcggc
gagcggttcgatacccctgtcaaaaccctcgtggacctggtgaacgagcagaccacgcgg
actcccgacgccaccgccgtggtgtatgagggccaacacttcacctaccacgacctcaat
gaggcgtcgaaccggttggggcactggctgatcgagcaggggataggcagcgaagaccgg
gtcgcggtacttcttgacaaatcgccggacctgatcgtcacggccttgggggtggtcaag
tccggggcggtgtatgtgcccgtggatcccagctacccgcaagaccggctggatttcatc
ctcgccgactgcgacgcgaaactggtgctgcgcacgccagtacgtgagctggccggatac
cgcagcgacgaccccaccgacgccgatcgaatccggccgctacggccagacaacacggcc
tatctcatctacacgtccggtaccaccggattgcccaaaggtgtcgcggtgccacaccgc
cccgtcgccgagtacttcgtctggttcaagggcgaatacgacgtcgacgacaccgaccgg
ctactgcaggtcgcctcacccagcttcgacgtctcgatcgccgagatcttcggcacgctg
gcctgtggcgcgcggatggtgataccacgccccgggggactcaccgacattggatatctc
accgccctgttgcgcgacgagggcatcacggcaatgcatttcgtgccgtccctactcggg
ctgttcctgtcgctgccgggtgtgagccagtggcggacgttgcagcgggtacccatcggc
ggggagccgctacccggtgaggtggccgacaagttccacgcgacattcgatgcgctgctg
cacaacttctacggtccaaccgaaaccgtgatcaacgccagccggtttaaagtggtgggc
ccacagggcacccgcatcgtgcccatcggccggcccaagatcaacaccaccatgcacctg
ctcgacgattcgttgcagccggtgccgaccggtgtgatcggcgagatctatattggaggg
acgcatgtcgcatacggataccatcgccgcgccgggctgaccgcggagcgattcgttgcc
gacccgtttaatcccggttcccgcatgtaccggtccggggatctggcgcgccgcaatgct
gacggtgacatcgagttcgtgggccgtgccgacgagcaggtcaagattcgcggattccga
atcgaactcggtgacgtagcagcggccatcgcggtcgaccctacggtcgggcaggccgtt
gtggtggttagcgacctgccgcggctgggcaagagtctggtgggctacgtgacacccgcc
gcgggcggcgacggacccgccgatgtcggcgtcgatctcgaccgcatccgcgcccgggtg
gccgcggcactgcctgaatatatgctgcccgcggcctatgttgtgctggatgagattccg
atcaccgcgcatggcaaaatcgaccgcgccgcgctgccggaaccgcagatcgcgtcggac
accgagttccgcgcgccgcagaccgccaccgagcggcgccttgcccaactgttcggtgag
ctgctcggccgcgaccgagtgggtgctgacgactcgttcttcgacctcggcggtcactcg
ctgctggcaaccaaactcgttgcggccgtgcgcaacgcgttcggcgtcgatgtcggtgtg
cgggagatcttcgaattcgccacggtgaccgcgttggccggacacatcgatacgttggat
tcggattcggcgaggccgcggctgacccgggtggatcatgacgggccagtgcgattgtcg
tcgtctcaaatgcgtagctggttcaactatcgcttcgacgggcccaacgccgtcaacaac
attcccttcgccgcggcattgcatgggccctgcgacaccaacgcgttcgcggcggccatc
accgatgtggtggcacgccacgagatcctgcgcaccgtctaccgcgagatcggcggcgtg
ccacaccagatcatccagccgcccgccgaggtgccggtgcggtgcgccgccgggtccgac
gccgcgtggctgcgagccgaactgaacaacgagcgaggttacgttttcgacctggaaacc
gactggccgatccgggcggcgctgctgagcacgccggagcagaccgtgttgtcgctggtg
gtgcatcacatcgccggcgaccactggtcggctggggtgttgttcaccgatctgctgacc
gcataccgggcccgcagcaccggacaacggccgtcgtgggcaccgctgccggtgcagtac
gccgactacagcgtgtggcagtcggcgctactcgacgacggtgcgggcatcgtcggtccg
caacgcgactactggatccgccagctggggggcctggcaggcgaaaccggtctgcgcccg
gacttcccgcgcccggccctgctcagcggtgccggtgacgcggtcgaatttcgtctcggc
gccgcgatccgcgacaaattggctgccgtgagccgagacctcggtgtcaccgagttcatg
ctgctacaggccgccgtcgcggtggtgttacacaaggccggcggcggggtagacgtcccc
atcggcgccccggtggccggtcgcagcgaggccaacctggaccagctcatcgggttcttc
atcaacatcgtggtgttgcgcaacgacctgcgcgggaaccccacgctgcgcgaggtgctg
cagcgcaccaggcagatggcgctggcagcgtatgcacatcaggacctgccgttcgaccag
gtggtggaggcggtcaacccccagcggtcgctgtcccgcaatccgttgttcgacattgtt
gtgcacgttcgcgaacaaatgccgcaagaccacgtcatcgacaccgggcccgacggtgac
accacgttgcgcgtgctggagccgacattcgatgccgcgcaagccgatctatcggtcaac
ttcttcgcctgcggcgacgagtaccgcggccacgtcatctaccgcaccgagttgtatgag
cgcgccaccgcacaacgcttcgccgactggctagtccgtgtcgtcgaggcgttcgccgac
cgtccggaccaaccgctgcgcgaggtcgagatggtcagcgcgcaagccagacggcgcatt
ttggaccggtccaatgcgggcgccggaacggcccgggtgtacctgcttgacgacgcactt
aagcccgttccggtaggcgtggtgggtgacgtttattacggtggcggtcccgccgtcggt
gcccggttggcccggccatcggagaccgcgacccgattcgttgccgatccgttcgccgcg
caaccgggttctcggctctaccgcaacggcgagcgcggagtgtggaaggccgacggccaa
ctggagctgctggccgaaatcgaacggctgccaacggcgcaggcggcaccggtgccggcc
gagcccgccgacaccgaaaccgagcgcgcgctggctgccatcctcgccgacgtgctcgag
gtgggggaggtcggacgctacgacgacttcttcaacctcggcggcgacagcatcctcgcg
actcaggtggctgcccgggctcgagatggcgggataccgctgaccgcgcggatggttttc
gagcatcccgttttgtgtgagctcgccgccgcggtcgacgccaagcctcacgtcgaggcc
gagccggacgacaagcatcacgcgccgatgagcacatcagggctttccccagacgaactg
tcggccctgaccgcgtcatgggaccagtggccgtga

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