KEGG   Mycobacterium tuberculosis variant microti: RN08_3624
Entry
RN08_3624         CDS       T04291                                 
Name
(GenBank) bifunctional protein acetyl-/propionyl-CoA carboxylase subunit alpha AccA
  KO
K11263  acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
Organism
mmic  Mycobacterium tuberculosis variant microti
Pathway
mmic00061  Fatty acid biosynthesis
mmic00074  Mycolic acid biosynthesis
mmic00280  Valine, leucine and isoleucine degradation
mmic00620  Pyruvate metabolism
mmic00630  Glyoxylate and dicarboxylate metabolism
mmic00640  Propanoate metabolism
mmic01100  Metabolic pathways
mmic01110  Biosynthesis of secondary metabolites
mmic01120  Microbial metabolism in diverse environments
mmic01200  Carbon metabolism
mmic01212  Fatty acid metabolism
Module
mmic_M00082  Fatty acid biosynthesis, initiation
mmic_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
mmic_M00885  Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA)
mmic_M00886  Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA and KasB)
mmic_M00887  Mycolic acid biosynthesis, meromycolic acid + alpha-carboxyacyl-CoA + trehalose => TMM => TDM/mAGP/GMM
Brite
KEGG Orthology (KO) [BR:mmic00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    RN08_3624
   00630 Glyoxylate and dicarboxylate metabolism
    RN08_3624
   00640 Propanoate metabolism
    RN08_3624
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    RN08_3624
   00074 Mycolic acid biosynthesis
    RN08_3624
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    RN08_3624
Enzymes [BR:mmic01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     RN08_3624
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     RN08_3624
    6.4.1.3  propionyl-CoA carboxylase
     RN08_3624
SSDB
Motif
Pfam: CPSase_L_D2 Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Biotin_lipoyl_2 Dala_Dala_lig_C Phage_cement_2 LAL_C2 Peptidase_M23
Other DBs
NCBI-ProteinID: AMC61051
LinkDB
Position
3657075..3658877
AA seq 600 aa
MASHAGSRIARISKVLVANRGEIAVRVIRAARDAGLPSVAVYAEPDAESPHVRLADEAFA
LGGQTSAESYLDFAKILDAAAKSGANAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSI
RDLGDKVTARHIAARAQAPLVPGTPDPVKGADEVVAFAEEYGLPIAIKAAHGGGGKGMKV
ARTIDEIPELYESAVREATAAFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCS
LQRRYQKLVEEAPAPFLTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGLISFLEVN
TRLQVEHPVTEETAGIDLVLQQFRIANGEKLDITEDPTPRGHAIEFRINGEDAGRNFLPA
PGPVTKFHPPSGPGVRVDSGVETGSVIGGQFDSMLAKLIVHGADRAEALARARRALNEFG
VEGLATVIPFHRAVVSDPAFIGDANGFSVHTRWIETEWNNTIEPFTDGEPLDEDARPRQK
VVVEIDGRRVEVSLPADLALSNGGGCDPVGVIRRKPKPRKRGAHTGAAASGDAVTAPMQG
TVVKFAVEEGQEVVAGDLVVVLEAMKMENPVTAHKDGTITGLAVEAGAAITQGTVLAEIK
NT seq 1803 nt   +upstreamnt  +downstreamnt
gtggctagtcacgccggctcgaggatcgctcggatctctaaggttctcgtcgccaatcgc
ggcgagatcgcagtgcgggtgatccgggcggcccgcgacgccggcctgcccagcgtggcg
gtgtacgccgaacccgacgccgagtccccgcatgttcggctggccgacgaggcgttcgcg
ctgggcggccagacctcggcggagtcctatctggacttcgccaagatcctcgacgcggca
gccaagtccggggccaacgccatccaccccggctacggcttcctagcggaaaatgccgac
ttcgcccaggcggtgatcgacgccggcctgatctggatcggccccagcccgcagtcgatc
cgcgacctgggcgacaaggtcacggcccgtcacatcgcggcccgcgctcaggcgcccctg
gtgccgggtacccccgatccggtcaaaggcgccgacgaggtggtggcattcgccgaggag
tacggcctgccgatcgcgatcaaggccgcccacggcggcggcggcaagggcatgaaggtg
gcccgcaccatcgacgagattccggagctgtacgagtcggcggtgcgcgaggccacggcc
gcgttcggccgcggtgagtgctacgtggagcgctatctcgacaagccgcgccacgtcgaa
gcacaggtgatcgccgaccagcacggcaacgtcgtcgtcgccggcacccgggactgctcg
ctgcagcgccgctaccagaagctggtcgaggaggcgcccgcaccgttcctgaccgacttt
caacgcaaagagatccacgactcggccaaacggatttgcaaagaggcccattaccacggc
gccggcaccgtcgaatacctggtcggtcaggacggcttgatctcgttcttggaggtcaac
acgcgccttcaggtagaacacccggtcaccgaggaaaccgcgggcatcgacttggtgctg
cagcaattccggatcgccaacggcgaaaagctggacatcaccgaggatcccaccccgcgc
gggcacgccatcgaattccggatcaacggcgaggacgcggggcgtaacttcctaccggcg
cccgggccggtgacaaagttccacccgccgtccggccccggtgtgcgggtggactccggt
gtcgagaccggctcggtgatcggcggccagttcgactcgatgctggccaagctgatcgtg
cacggtgccgaccgcgccgaggcgctggcgcgggcccggcgcgcgctgaacgagttcggt
gtcgaaggcctggcgacggtcatcccgtttcaccgcgccgtggtgtccgacccggcattc
atcggcgacgcgaacggcttttcggtacatacccgctggatcgagaccgagtggaataac
accatcgagccctttaccgacggcgaacctctcgacgaggacgcccggccgcgtcagaag
gtggtcgtcgaaatcgacggtcgccgcgtcgaagtctcgctgccggctgatctcgcgctg
tccaatggcggcggttgcgacccggtcggtgtcatccggcgcaagcccaagccgcgcaag
cggggtgcgcacaccggcgcggcggcctccggtgacgcggtgaccgcgcctatgcagggc
accgtagttaagttcgcggtcgaagaagggcaagaggtcgtggccggcgacctagtggtg
gtcctcgaggcgatgaagatggaaaacccggtcaccgcgcataaggatggcaccatcacc
gggctggcggtcgaggcgggcgcggccatcacccagggcacggtgctcgccgagatcaag
taa

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