KEGG   Micromys minutus (European harvest mouse): 308418187
Entry
308418187         CDS       T12044                                 
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform 3
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
mmiu  Micromys minutus (European harvest mouse)
Pathway
mmiu01521  EGFR tyrosine kinase inhibitor resistance
mmiu01522  Endocrine resistance
mmiu04012  ErbB signaling pathway
mmiu04066  HIF-1 signaling pathway
mmiu04140  Autophagy - animal
mmiu04150  mTOR signaling pathway
mmiu04151  PI3K-Akt signaling pathway
mmiu04152  AMPK signaling pathway
mmiu04211  Longevity regulating pathway
mmiu04213  Longevity regulating pathway - multiple species
mmiu04350  TGF-beta signaling pathway
mmiu04371  Apelin signaling pathway
mmiu04666  Fc gamma R-mediated phagosome formation
mmiu04714  Thermogenesis
mmiu04910  Insulin signaling pathway
mmiu04931  Insulin resistance
mmiu05163  Human cytomegalovirus infection
mmiu05165  Human papillomavirus infection
mmiu05170  Human immunodeficiency virus 1 infection
mmiu05200  Pathways in cancer
mmiu05205  Proteoglycans in cancer
mmiu05207  Chemical carcinogenesis - receptor activation
mmiu05210  Colorectal cancer
mmiu05212  Pancreatic cancer
mmiu05221  Acute myeloid leukemia
mmiu05224  Breast cancer
mmiu05225  Hepatocellular carcinoma
mmiu05226  Gastric cancer
mmiu05231  Choline metabolism in cancer
mmiu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mmiu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    308418187 (RPS6KB2)
   04350 TGF-beta signaling pathway
    308418187 (RPS6KB2)
   04371 Apelin signaling pathway
    308418187 (RPS6KB2)
   04066 HIF-1 signaling pathway
    308418187 (RPS6KB2)
   04151 PI3K-Akt signaling pathway
    308418187 (RPS6KB2)
   04152 AMPK signaling pathway
    308418187 (RPS6KB2)
   04150 mTOR signaling pathway
    308418187 (RPS6KB2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    308418187 (RPS6KB2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagosome formation
    308418187 (RPS6KB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    308418187 (RPS6KB2)
  09149 Aging
   04211 Longevity regulating pathway
    308418187 (RPS6KB2)
   04213 Longevity regulating pathway - multiple species
    308418187 (RPS6KB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    308418187 (RPS6KB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    308418187 (RPS6KB2)
   05205 Proteoglycans in cancer
    308418187 (RPS6KB2)
   05207 Chemical carcinogenesis - receptor activation
    308418187 (RPS6KB2)
   05231 Choline metabolism in cancer
    308418187 (RPS6KB2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    308418187 (RPS6KB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    308418187 (RPS6KB2)
   05212 Pancreatic cancer
    308418187 (RPS6KB2)
   05225 Hepatocellular carcinoma
    308418187 (RPS6KB2)
   05226 Gastric cancer
    308418187 (RPS6KB2)
   05221 Acute myeloid leukemia
    308418187 (RPS6KB2)
   05224 Breast cancer
    308418187 (RPS6KB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    308418187 (RPS6KB2)
   05163 Human cytomegalovirus infection
    308418187 (RPS6KB2)
   05165 Human papillomavirus infection
    308418187 (RPS6KB2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    308418187 (RPS6KB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    308418187 (RPS6KB2)
   01522 Endocrine resistance
    308418187 (RPS6KB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmiu01001]
    308418187 (RPS6KB2)
Enzymes [BR:mmiu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     308418187 (RPS6KB2)
Protein kinases [BR:mmiu01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   308418187 (RPS6KB2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7
Other DBs
NCBI-GeneID: 308418187
NCBI-ProteinID: XP_080769686
LinkDB
Position
2:53604879..53611335
AA seq 511 aa
MAAVFDLDLETEEGSEGEGEPEFNPADVCPLGELRAAGLETVGHYEEVELTESSVNLGPE
RIGPHCFELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEI
LVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLA
KKFLKRNPNHRIGGGPGDAADVQRHPFFRHINWDDLLARRVDPPFRPSLQSEEDVSQFDA
RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT
PIRYLGTGQASPSSFLPLRGSGPVLAHQSLWSHLYLHSCHHHHHHHPQALPPFPFVPPQE
PRSLKRDGAAQGARRIEEKAAGRTWLAPTCG
NT seq 1536 nt   +upstreamnt  +downstreamnt
atggcggccgtgtttgatttagacttggagaccgaggaagggagtgagggcgagggcgaa
ccggagttcaaccctgcggacgtgtgtccccttggcgagttaagggctgctggcctggag
acagtggggcactatgaggaggtggagctgacagagagcagcgtcaacctgggccccgag
cgcatcggaccccactgctttgagctactgagtgtgctgggcaaggggggctatggcaag
gtgtttcaggtgagaaaagtgcaaggcaccaacttgggcaaaatatatgccatgaaagtc
ttgagaaaggccaagattgtatgcagtgccaaggacacagcacatacccgggctgagcgg
aacattctagaatctgtaaagcatcccttcattgtagaattggcctatgctttccagaca
ggtggcaaactctacctcatcctggagtgcctcagtggtggtgagctcttcacacatctt
gagcgagaaggcatcttcctggaagacacagcctgcttctacctggcagagatcacatta
gccctgggccatctccattcccaaggcatcatttacagggatctcaagcctgagaacatc
atgctcaacagccagggccacatcaaactgacagactttggactctgcaaagagtccatt
catgagggtgctatcactcacaccttctgtggcaccatcgagtacatggccccagagatt
ctagtgcgcactggtcacaaccgagccgtggactggtggagcctgggagccctgatgtac
gacatgctcactggatcgccgcccttcaccgcagagaaccggaagaaaactatggataaa
atcattaaagggaagctggtgctgcccccctacctcaccccggatgcccgggaccttgcc
aaaaagtttctgaagcgaaatcctaatcatcgaattgggggtggcccaggagacgctgct
gatgtgcagaggcacccctttttccggcacatcaattgggatgacctcttggcccgtcgt
gtggatccccccttcaggccaagtctgcaatcagaagaagatgtgagccagtttgatgca
cgattcacacggcagacgccagtagatagtccagatgacacagccctcagtgagagtgcc
aaccaagccttcctgggcttcacatatgtggcaccttcggtcttggacagcatcaaagag
ggcttctccttccagcctaagctgcgttcccccagacgccttaacagcagtccccgcact
cccatcaggtacctagggacagggcaggcatccccctcaagttttctccctttgaggggt
tccggcccagtcctggcccaccagagcctatggagccatctctacctccactcttgccac
caccatcatcaccaccacccacaagcactgccccccttcccattcgtcccccctcaggaa
ccaagaagtctaaaaagggacggggccgcccagggcgctaggagaatagaggaaaaggca
gctgggagaacctggctggctccaacctgcggatga

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