Mycobacterium sp. MOTT36Y: W7S_10840
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Entry
W7S_10840 CDS
T02113
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mmm
Mycobacterium sp. MOTT36Y
Pathway
mmm00300
Lysine biosynthesis
mmm00550
Peptidoglycan biosynthesis
mmm01100
Metabolic pathways
mmm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mmm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
W7S_10840
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
W7S_10840
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
W7S_10840
Enzymes [BR:
mmm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
W7S_10840
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AFJ35139
UniProt:
I2ACW5
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All DBs
Position
2342124..2343671
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AA seq
515 aa
AA seq
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MIELTVAEIADIVGGTLADISPQDAARRRVTGTVEFDSRAVGPGGLFLALPGARSDGHDH
AGAAIAAGAVAVLAARPVGVPAVVVAPAGASGSRAGVLEHDPDGSGAAVLAALAKLAQVV
AAELVAGGLRIVGITGSSGKTSTKDLVAAVLKPLGEVVAPPGSFNNELGHPWTVLRATPD
TDFLVLEMSARHPGNIAALAEIAPPAIGVVLNVGTAHLGEFGSREAIAQTKSELPQSVPA
SGVVILNADDPAVAAMAGVTAARVVRVSRAENTSAGPSQLWAGPVSLDEVARPCFTLHHR
DASGTTQAQVRLGVYGDHQVTNALCAAAVALECGADVDQVAAALAGAGPVSRHRMHVTTR
ADGVTVIDDAYNANPDSMRAGLQALAWIAHGGGDRPAEKRRSWAVLGEMAELGEDAIAEH
DRIGRLAVRLDVSRLVVVGSGRSMSAMHHGAVMEGSWGSADKGAVNVADSEAALALLRAE
LQPGDVVLVKASNAAGLGALADALVSQGSQGGARP
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagttgaccgtcgccgagatcgccgacatcgtcggcggcaccctggccgacatc
tcgccgcaggacgccgcgcgacgccgcgtcaccgggacggtggaattcgactcgcgcgcc
gtcggacccggcgggctgttcctggcgctgccgggcgcgcgctcggacggccacgaccac
gcgggcgcggcgatcgccgccggcgcggtggcggtgctggccgcccgaccggtcggcgtt
cccgccgtcgtcgtcgcccccgcgggcgcgtcgggatcgcgggccggggtgctcgagcac
gacccggacggctcgggcgcggcggtgctcgcggcgctggccaaattggcccaggtggtg
gccgccgaactggtcgccggcgggctcaggatcgtcgggatcaccggatcgtcggggaag
acgtcgaccaaggacctggtggccgccgtgctgaaaccgctcggcgaggtggtcgccccg
cccgggtcgttcaacaacgagctcgggcatccgtggaccgtgctgcgcgcgacgcccgac
accgacttcctggtcctcgagatgtcggcgcgccacccgggcaacatcgccgcgctggcc
gagatcgccccgccggcgatcggcgtcgtcctcaacgtcggcaccgcgcacctgggcgag
ttcggctcgcgcgaggccatcgcacagacgaaatccgaactgccccaatctgttccggca
tccggggtggtgatcctcaatgccgacgacccggcggtggcggccatggccggcgtgacc
gcggcccgggtggtgcgggtcagccgtgccgagaacaccagcgcgggccccagccagctg
tgggccgggcccgtctcgctcgacgaggtggccaggccgtgcttcacgctgcaccaccgc
gacgcctcggggaccactcaggcgcaggtccggctcggcgtctacggcgaccaccaggtg
accaacgcgctgtgcgccgccgcggtcgcgctggaatgcggcgccgacgtcgaccaggtg
gcggccgcactcgccggcgccggccccgtctcgcggcaccggatgcacgtcaccacgcgc
gccgacggcgtcaccgtgatcgacgacgcctacaacgccaaccccgattcgatgcgcgcc
gggctgcaggcgttggcctggatcgcccacggcgggggggaccggccggccgaaaagcgc
aggagttgggccgtgctcggtgagatggccgaactcggcgaggacgcgatcgccgagcat
gatcgcatcggccggctggccgtgcgcttagatgtgtctcgactcgttgtcgtgggaagt
gggaggtcgatgagcgccatgcaccacggagcggtcatggagggttcgtggggctcggcc
gataagggggccgtcaacgtggccgacagcgaggccgccctggcgttgctgcgggccgag
ctgcaacccggcgacgtcgtgctggtcaaggcctccaacgcggccgggctgggggcgctg
gccgacgccctggtatcacaaggctcgcagggcggtgcccgcccgtga
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