KEGG   Marmota marmota marmota (Alpine marmot): 107134485
Entry
107134485         CDS       T09644                                 
Name
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma01522  Endocrine resistance
mmma04010  MAPK signaling pathway
mmma04015  Rap1 signaling pathway
mmma04068  FoxO signaling pathway
mmma04071  Sphingolipid signaling pathway
mmma04114  Oocyte meiosis
mmma04148  Efferocytosis
mmma04218  Cellular senescence
mmma04261  Adrenergic signaling in cardiomyocytes
mmma04370  VEGF signaling pathway
mmma04380  Osteoclast differentiation
mmma04517  IgSF CAM signaling
mmma04550  Signaling pathways regulating pluripotency of stem cells
mmma04611  Platelet activation
mmma04613  Neutrophil extracellular trap formation
mmma04620  Toll-like receptor signaling pathway
mmma04621  NOD-like receptor signaling pathway
mmma04622  RIG-I-like receptor signaling pathway
mmma04625  C-type lectin receptor signaling pathway
mmma04657  IL-17 signaling pathway
mmma04658  Th1 and Th2 cell differentiation
mmma04659  Th17 cell differentiation
mmma04660  T cell receptor signaling pathway
mmma04664  Fc epsilon RI signaling pathway
mmma04668  TNF signaling pathway
mmma04670  Leukocyte transendothelial migration
mmma04714  Thermogenesis
mmma04722  Neurotrophin signaling pathway
mmma04723  Retrograde endocannabinoid signaling
mmma04728  Dopaminergic synapse
mmma04750  Inflammatory mediator regulation of TRP channels
mmma04912  GnRH signaling pathway
mmma04914  Progesterone-mediated oocyte maturation
mmma04917  Prolactin signaling pathway
mmma04926  Relaxin signaling pathway
mmma04932  Non-alcoholic fatty liver disease
mmma04933  AGE-RAGE signaling pathway in diabetic complications
mmma04935  Growth hormone synthesis, secretion and action
mmma04936  Alcoholic liver disease
mmma05014  Amyotrophic lateral sclerosis
mmma05020  Prion disease
mmma05022  Pathways of neurodegeneration - multiple diseases
mmma05132  Salmonella infection
mmma05133  Pertussis
mmma05135  Yersinia infection
mmma05140  Leishmaniasis
mmma05142  Chagas disease
mmma05145  Toxoplasmosis
mmma05152  Tuberculosis
mmma05161  Hepatitis B
mmma05163  Human cytomegalovirus infection
mmma05167  Kaposi sarcoma-associated herpesvirus infection
mmma05169  Epstein-Barr virus infection
mmma05170  Human immunodeficiency virus 1 infection
mmma05171  Coronavirus disease - COVID-19
mmma05205  Proteoglycans in cancer
mmma05208  Chemical carcinogenesis - reactive oxygen species
mmma05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmma05415  Diabetic cardiomyopathy
mmma05417  Lipid and atherosclerosis
mmma05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107134485
   04015 Rap1 signaling pathway
    107134485
   04370 VEGF signaling pathway
    107134485
   04668 TNF signaling pathway
    107134485
   04068 FoxO signaling pathway
    107134485
   04071 Sphingolipid signaling pathway
    107134485
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    107134485
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    107134485
  09143 Cell growth and death
   04114 Oocyte meiosis
    107134485
   04218 Cellular senescence
    107134485
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    107134485
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    107134485
   04613 Neutrophil extracellular trap formation
    107134485
   04620 Toll-like receptor signaling pathway
    107134485
   04621 NOD-like receptor signaling pathway
    107134485
   04622 RIG-I-like receptor signaling pathway
    107134485
   04625 C-type lectin receptor signaling pathway
    107134485
   04660 T cell receptor signaling pathway
    107134485
   04658 Th1 and Th2 cell differentiation
    107134485
   04659 Th17 cell differentiation
    107134485
   04657 IL-17 signaling pathway
    107134485
   04664 Fc epsilon RI signaling pathway
    107134485
   04670 Leukocyte transendothelial migration
    107134485
  09152 Endocrine system
   04912 GnRH signaling pathway
    107134485
   04914 Progesterone-mediated oocyte maturation
    107134485
   04917 Prolactin signaling pathway
    107134485
   04926 Relaxin signaling pathway
    107134485
   04935 Growth hormone synthesis, secretion and action
    107134485
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    107134485
  09156 Nervous system
   04728 Dopaminergic synapse
    107134485
   04723 Retrograde endocannabinoid signaling
    107134485
   04722 Neurotrophin signaling pathway
    107134485
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    107134485
  09158 Development and regeneration
   04380 Osteoclast differentiation
    107134485
  09159 Environmental adaptation
   04714 Thermogenesis
    107134485
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    107134485
   05208 Chemical carcinogenesis - reactive oxygen species
    107134485
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    107134485
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    107134485
   05161 Hepatitis B
    107134485
   05171 Coronavirus disease - COVID-19
    107134485
   05163 Human cytomegalovirus infection
    107134485
   05167 Kaposi sarcoma-associated herpesvirus infection
    107134485
   05169 Epstein-Barr virus infection
    107134485
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    107134485
   05135 Yersinia infection
    107134485
   05133 Pertussis
    107134485
   05152 Tuberculosis
    107134485
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    107134485
   05140 Leishmaniasis
    107134485
   05142 Chagas disease
    107134485
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    107134485
   05020 Prion disease
    107134485
   05022 Pathways of neurodegeneration - multiple diseases
    107134485
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    107134485
   05418 Fluid shear stress and atherosclerosis
    107134485
   05415 Diabetic cardiomyopathy
    107134485
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    107134485
   04932 Non-alcoholic fatty liver disease
    107134485
   04933 AGE-RAGE signaling pathway in diabetic complications
    107134485
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    107134485
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmma01001]
    107134485
Enzymes [BR:mmma01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     107134485
Protein kinases [BR:mmma01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   107134485
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Cas_CT1975
Other DBs
NCBI-GeneID: 107134485
NCBI-ProteinID: XP_015332070
LinkDB
Position
Unknown
AA seq 186 aa
MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEV
VGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFHGANPLAVDLLGRMLVLDSDQRVS
AAEALAHAYFSQYHDPDDEPEAEPYDESVEATERTVEEWKELTYQEVLSFKPPEPPQPSG
SLEIEQ
NT seq 561 nt   +upstreamnt  +downstreamnt
atgacaggatacgtggccacacgctggtaccgggcgcccgagatcatgctcaattggatg
cattacaatcagacagtggacatctggtctgtgggttgcatcatggctgaattgctccag
ggaaaagccctcttcccagggaatgactacattgaccagctgaagcgcatcatggaagtg
gtgggcacacccagccctgaggttctggcaaagatatcctcggagcatgcccggacatac
atccagtccttgccccccatgccccagaaggacctcagcagcatctttcatggagccaac
cccctggctgtagaccttcttggaaggatgctggtgctggacagtgaccagagggtcagt
gcagctgaggcactggcccatgcgtatttcagccagtaccacgacccagatgatgagcca
gaggctgagccctatgatgaaagcgttgaggccacggagcgcacggtggaggagtggaag
gagctcacttaccaggaagtcctcagcttcaagcccccagagccaccgcagccgagtggc
agcctagagattgagcaatga

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