Marmota marmota marmota (Alpine marmot): 107136445
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Entry
107136445 CDS
T09644
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00230
Purine metabolism
mmma00670
One carbon pool by folate
mmma01100
Metabolic pathways
mmma01523
Antifolate resistance
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
107136445 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
107136445 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
107136445 (Gart)
Enzymes [BR:
mmma01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
107136445 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
107136445 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
107136445 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
RimK
Sacchrp_dh_NADP
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
107136445
NCBI-ProteinID:
XP_015334198
Ensembl:
ENSMMMG00000001006
UniProt:
A0A8C6EMN5
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHALAWKLAQSHHVKQVLIAPGNAGTACSEKISNTDISITDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGDLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHRIP
TAQWRAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQDKAF
GAAGETIVVEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPTP
QVSEDLLLKIKNTVLQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPIWLENHTAITVVMASKGYPGAYTKGVEVTGFSET
TALGLEVFHAGTTYKNGRVVTSGGRVLTVTAIHENLISALEKAKKGLTAIKFEGAIYRKD
IGFRAIAFLQQPRGFTYKGSGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHNTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNMSEAVIAGIATACEQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVIVGIASSGLHSNGFSLVRKIVANSSLQYSSPAPDGCGDQSLGDLLLTPTK
IYSHSLLPVIRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRVFSWLQQEG
QLSEEEMARTFNCGIGAVLVVSKDQTGQILNDIQQCQEEAWVIGSVVACPEGSPRVKVKN
LLETMQMSKSVSVNGSLKNHFSAQPKKARVAVLISGTGSNLQALIDSTQDPNSYAHIVVV
ISNKAAVAGLDKAEKAGIPTRVINHKLYKNRIEFDNAIDKVLEEFSTDIVCLAGFMRILS
GPFVKKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGIVQLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagctcgagtacttgtcattggcagtggcggaagggaacatgcgctggcctggaag
cttgcacagtctcatcatgtcaaacaagtgcttattgccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaatactgacatctcgatcactgatcatactgcccttgctcag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacccctggctgct
ggaattgttggggacctgacctctgcaggagtgcgatgttttggccccacagcagaagca
gctcagttagaatccagcaaaagatttgccaaagagtttatggaccgacacagaatccca
actgcacaatggagagctttcaccaaacctgaagaggcctgtagcttcattatgagtgcg
gacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggagtgattgtt
gcaaagagcaaagaggaagcctgcaaagctgtacaggagatcatgcaggataaagctttt
ggagcagctggagaaacaattgttgttgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgtttcactgatgggaggacagtggcccccatgcctccagcacaggaccataaacga
ttactggagggagatcaaggccccaacacagggggaatgggagcctattgtcccacacct
caggtttctgaggatctgttactaaaaattaaaaatactgtccttcagaggacagtagat
ggcatgcagcaagagggtactccatacacagggattctttatgctggcataatgctgacc
aaggatggcccaaaagttttggaatttaattgccgttttggtgatccagagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtaattcagtccaccttagatggcctg
ctgtgcacatctttacccatttggctagaaaaccacactgccataactgtggtcatggca
agtaaaggttatcctggagcttacaccaagggtgtggaggtaacagggttttctgagact
acagctttaggactagaagtgttccatgcaggcactacctacaaaaatggcagagtggtg
accagcgggggaagagtccttacagtaacagccattcatgaaaacctcatatctgccctt
gaaaaagccaagaagggactcactgctataaagtttgagggagcaatttacaggaaagac
atcggctttcgcgccatagctttccttcagcagcccaggggcttcacttacaagggatct
ggggtagacattgcagctggaaatatgctggttaagaaaataaagcctttagcaaaagcc
acctccagaccaggctgtgacgtagatcttggaggttttgctggtctttttgatttgaaa
gcggctggtttcaaagatcctcttctggcctctggaactgatggtgttggaactaaactc
aagattgcccagctgtgcaataaacacaatacaattggtcaagatttggttgcaatgtgt
gtaaatgatattctggcacaaggagcagagcccctcttcttccttgattacttctcctgt
ggaaagcttgaccttaatatgtctgaagccgtcattgccggaattgctacagcttgtgaa
caggctggatgtgctctccttggaggtgaaacagcagaaatgcccgacatgtatcctcct
ggagagtatgatctagctggttttgctgttggtgctatggagcgggatcagaaactgcct
cacctggaaaggatcactgaaggggatgttattgttggaatagcttcatctggtctccac
agcaatggatttagccttgtgaggaaaattgtggcaaactcttccctgcagtactcctct
ccagcacctgatggttgtggtgaccagtccttaggggacttacttctaactccaaccaaa
atctacagccattctttgttacctgtcatacgttcaggacatgttaaagcctttgctcat
attactggtggaggactactggaaaacattcccagagttctccctcagaaatttggggtg
gatttagatgcccagacatggaggatccccagggtcttctcatggttacagcaggaagga
cagctctctgaagaagagatggccagaacattcaactgtggtattggagctgtccttgtg
gtatcaaaggatcagacagggcagattctaaatgatattcaacagtgccaggaagaagcc
tgggtgattggcagtgtggttgcatgtcctgaaggttcccctcgtgtgaaagtcaagaat
ctgctcgaaaccatgcaaatgagcaagtcagtgtcagtgaacggctccttgaaaaatcac
ttctctgcccaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatcgaac
ctccaagcactcatagacagtactcaggatccaaatagctacgcacacattgttgttgtt
atctccaataaagccgcagtggctggtttagataaggcagaaaaagctggtatcccaacc
agagtaattaatcataaattatataaaaatcggatagaatttgacaatgcaattgacaaa
gtccttgaagagttctccacagacatagtctgtcttgcagggttcatgagaattctctct
ggcccctttgtcaaaaaatgggatggaaaaatgctgaacatccacccttccttgctccct
tcttttaagggttcaaatgctcatgagcaagccctggaagctggagtcacaattactgga
tgcactgtacactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttcctgttaaaaggggtgacactgttgcaactttgtctgaaagagtaaaattagcagaa
cataaaatatttcctgcagccctccagctggtggccagtggaattgtacagcttggagaa
aatggcaagatctgttgggtcaaagaggaatga
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