KEGG   Marmota marmota marmota (Alpine marmot): 107137576
Entry
107137576         CDS       T09644                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma00140  Steroid hormone biosynthesis
mmma01100  Metabolic pathways
mmma04913  Ovarian steroidogenesis
mmma04925  Aldosterone synthesis and secretion
mmma04927  Cortisol synthesis and secretion
mmma04934  Cushing syndrome
Module
mmma_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    107137576
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    107137576
   04925 Aldosterone synthesis and secretion
    107137576
   04927 Cortisol synthesis and secretion
    107137576
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107137576
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mmma00199]
    107137576
Enzymes [BR:mmma01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     107137576
Cytochrome P450 [BR:mmma00199]
 Cytochrome P450, animal type
  CYP11 family
   107137576
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 107137576
NCBI-ProteinID: XP_015335541
Ensembl: ENSMMMG00000003069
UniProt: A0A8C5YSU4
LinkDB
Position
Unknown
AA seq 363 aa
MMAPEVLKNFVPMLEAVAQDFIGVLNKRVKQQKSGNFSGDISDDLFRFAFESITNIIFGE
RLGMLEEIVDPEAQKFIDAIYQMFHTSVPMLSLPPELFRLFRTKTWRDHAAAWDTIFDKA
DKYTQNFYWDSRQKRNFSKYPGILYSLLGSNKLPFQDIQANITELLAGGVDTTSMTLQWH
MYEMARTPKVQEMLRAEVLAARRQAQGDINTMLQLVPLLKASIKETLRLHPISVTVQRYL
ENDLVLRGYIIPAKTLVQVANYAMGQESSFFTNPGNFNPNRWLDNDKNNTYFRYLGFGWG
IRQCLGRRIAELEMTIFLIHVLENFKIKIQHLSDVGTKFNLILMPEKPILFTFLPFKQNP
VLG
NT seq 1092 nt   +upstreamnt  +downstreamnt
atgatggctccagaggtcctcaagaacttcgtacccatgctggaggcggtggctcaagac
ttcattggtgtcctgaacaagcgtgtcaagcagcagaaatctgggaatttctcaggagac
atcagtgatgacctgttccgctttgcctttgagtccatcaccaacatcatatttggggag
cgcctggggatgctggaggagattgtggaccccgaggcccagaagttcattgatgccatc
tatcagatgttccacaccagtgtgcccatgctcagcctacccccagaactgtttcgcctc
ttcagaaccaagacctggagggaccatgcggccgcatgggacactatttttgataaagct
gacaaatatacacagaacttctactgggactcgagacagaaaagaaacttcagcaaatac
cctggaatcttgtatagtctcctgggaagtaacaagctacccttccaggacatccaagcc
aacattactgagctattagcaggaggtgtggacacgacatccatgaccctgcagtggcac
atgtacgagatggcacgcaccccaaaagtgcaggagatgctgagggcagaggttctggct
gcccggcgccaggcccagggagacataaacacaatgctgcagttggtcccactcctcaaa
gccagtatcaaggagacactgagactccaccccatctctgtgactgtgcagagatatctt
gagaatgacttggttcttcgtggctacataattcctgccaagacactggttcaggtggcc
aattatgctatgggccaagaatccagcttcttcaccaaccctggcaatttcaacccaaac
cgatggctggacaatgacaagaacaacacctacttccggtaccttggctttggctggggt
attcggcagtgtctgggccgccggattgcagagctggagatgaccatattcctcattcac
gtgctggagaacttcaaaattaaaatccaacatctcagcgatgtgggtaccaagttcaac
ctcatcttgatgcctgagaagcccatcttattcaccttcttgcccttcaaacagaaccca
gttctgggatga

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