Marmota marmota marmota (Alpine marmot): 107137969 Help Entry 107137969         CDS       T09644                                  Symbol Pkm Name (RefSeq) pyruvate kinase PKM isoform X1   KO K00873   pyruvate kinase [EC:2.7.1.40] Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma00010   Glycolysis / Gluconeogenesis mmma00620   Pyruvate metabolism mmma01100   Metabolic pathways mmma01200   Carbon metabolism mmma01230   Biosynthesis of amino acids mmma04922   Glucagon signaling pathway mmma04930   Type II diabetes mellitus mmma05165   Human papillomavirus infection mmma05203   Viral carcinogenesis mmma05230   Central carbon metabolism in cancer Module mmma_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mmma_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:mmma00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     107137969 (Pkm)    00620 Pyruvate metabolism     107137969 (Pkm)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     107137969 (Pkm)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     107137969 (Pkm)    05230 Central carbon metabolism in cancer     107137969 (Pkm)   09172 Infectious disease: viral    05165 Human papillomavirus infection     107137969 (Pkm)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     107137969 (Pkm)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mmma04131]     107137969 (Pkm)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:mmma04147]     107137969 (Pkm) Enzymes [BR:mmma01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      107137969 (Pkm) Membrane trafficking [BR:mmma04131]  Autophagy   Chaperone mediated autophagy (CMA)    Selective cargos     107137969 (Pkm) Exosome [BR:mmma04147]  Exosomal proteins   Proteins found in most exosomes    107137969 (Pkm) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C HpcH_HpaI Motif Other DBs NCBI-GeneID:  107137969 NCBI-ProteinID:  XP_015335953 Ensembl:  ENSMMMG00000004228 UniProt:  A0A8C5YSY6 LinkDB All DBs Position Unknown AA seq 568 aa AA seqDB search MQVGPRSGQGAEPNKEGYITENPSPGNQRTSEEASAAMSKPHSEAGTAFIQTQQLHAAMA DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEY HAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKIT LDNSYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLLVKEKGADFLVTEVENGGAL GSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKILGEKGK NIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKP VICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAR EAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVAR YRPRAPIIAVTRNPQTARQAHLYRGIFPVVCKDPVQDAWAEDVDLRVNLAMNVGKARGFF KKGDVVIVLTGWRPGSGFTNTMRVVPVP NT seq 1707 nt NT seq  +upstreamnt  +downstreamnt atgcaagtggggccaaggagcggccaaggtgctgagccaaataaagaggggtatatcacc gaaaacccaagcccagggaaccaaaggacctcagaagaagcctcagcagccatgtcgaag ccccatagtgaagccgggactgctttcattcagacccagcagctgcacgcagccatggct gacacattcctggaacacatgtgccgcctggacattgactctccacccatcactgccagg aacactggcatcatttgtaccattggcccagcttcccgatcagtggaaatgttgaaggag atgattaagtctggcatgaacgtcgctcgtctaaacttctctcacggaactcacgagtac catgcagagaccatcaagaatgtccgtgcagccacagaaagctttgcttctgaccccatt ctctatcggccagttgctgtggctctggacactaaaggacctgagatccgaactgggctc atcaagggcagcggcaccgcagaggtggagctgaagaagggagccactcttaagatcact ctggataactcctacatggagaagtgtgatgagaacatcctatggctggactacaagaac atttgcaaagtggtggaagtgggtagcaagatttatgtggatgatggacttatttctctg ctggtgaaggaaaaaggtgctgactttctggtgacagaggtggaaaatggtggcgccttg ggcagcaagaagggtgtgaaccttcctggggctgctgtggacctgcctgcagtgtcagaa aaggacatccaggatctgaagtttggggttgagcaggatgtagacatggtgtttgcatct ttcatccgcaaagcatctgatgtccatgaagttaggaagatcctgggagagaaaggaaag aacatcaagattatcagcaaaattgagaatcacgaaggagttcgaagatttgatgagatc ctggaggccagcgatgggatcatggtggcccgtggtgatctaggcattgagattcctgca gagaaggtcttccttgctcagaagatgatgattgggcggtgcaaccgagctgggaagcct gtcatctgtgctacacagatgctggagagcatgatcaagaagccccgccccacccgggct gagggcagtgatgtggccaatgcagtccttgatggagctgactgcatcatgctgtctgga gaaacagccaaaggggactaccctctggaggctgttcgcatgcagcacctgattgcccgt gaggcagaggctgccatctaccacttgcaattatttgaggagctccgccgcctggcgccc attaccagcgaccccacagaagccgccgccgtgggtgctgtggaggcatccttcaagtgc tgcagtggggccattatcgtgctcaccaagtctggcaggtctgctcaccaggtagccaga taccgcccacgtgctcccatcattgccgtgacacggaatccccagacagctcgccaggcc cacctgtaccgtggcatcttccctgtggtgtgtaaggatccagtccaggatgcctgggct gaggatgtggacctccgagtgaacttggccatgaatgttggcaaggctcgaggcttcttc aagaagggagatgtggtcattgtgctgactggatggcgccctggctctggcttcaccaac accatgcgtgtagtacctgtgccatga

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