Marmota marmota marmota (Alpine marmot): 107138634
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Entry
107138634 CDS
T09644
Symbol
Ndufs1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00190
Oxidative phosphorylation
mmma01100
Metabolic pathways
mmma04714
Thermogenesis
mmma04723
Retrograde endocannabinoid signaling
mmma04932
Non-alcoholic fatty liver disease
mmma05010
Alzheimer disease
mmma05012
Parkinson disease
mmma05014
Amyotrophic lateral sclerosis
mmma05016
Huntington disease
mmma05020
Prion disease
mmma05022
Pathways of neurodegeneration - multiple diseases
mmma05208
Chemical carcinogenesis - reactive oxygen species
mmma05415
Diabetic cardiomyopathy
Module
mmma_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
107138634 (Ndufs1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
107138634 (Ndufs1)
09159 Environmental adaptation
04714 Thermogenesis
107138634 (Ndufs1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
107138634 (Ndufs1)
09164 Neurodegenerative disease
05010 Alzheimer disease
107138634 (Ndufs1)
05012 Parkinson disease
107138634 (Ndufs1)
05014 Amyotrophic lateral sclerosis
107138634 (Ndufs1)
05016 Huntington disease
107138634 (Ndufs1)
05020 Prion disease
107138634 (Ndufs1)
05022 Pathways of neurodegeneration - multiple diseases
107138634 (Ndufs1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
107138634 (Ndufs1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
107138634 (Ndufs1)
Enzymes [BR:
mmma01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
107138634 (Ndufs1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
107138634
NCBI-ProteinID:
XP_015336784
Ensembl:
ENSMMMG00000014566
UniProt:
A0A8C5ZJZ2
LinkDB
All DBs
Position
Unknown
AA seq
727 aa
AA seq
DB search
MLRIPVRRALVGLSKSPKGYVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYVEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLSYTSWEDALSRVAGMLQSFQGKNVAAVAGGLVDAEALVALKDLLNR
VDSETLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEAGVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGSHSFSQVLKDAKKPMVILGSSA
LQRNDGAAILAAVSSIAQTIRVTGGVADDWKVMNILHRVASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctgttagaagggccttagtgggcctttctaagtctcctaaaggatat
gttcgaaccactgccacagcagcaagcaacttgattgaagtgttcgttgatggtcagtct
gtcatggtggaaccagggactactgtcctccaagcttgtgagaaggttggcatgcagatc
cctcgattttgttatcatgaaaggttatctgttgctggaaactgcaggatgtgccttgtt
gaaattgagaaagctcctaaggttgtagctgcttgtgctatgccagtaatgaagggttgg
aatatcctgacaaactcagaaaaatctaagaaagccagagaaggggtgatggagttctta
ctagccaatcacccattggactgtcccatttgtgaccagggaggcgaatgtgatctgcag
gatcagtccatgatgtttggaagtgataggagccgatttttagagggtaaacgggctgtg
gaagacaagaacatcgggccattagtaaagaccatcatgactagatgcatacagtgtact
cgatgcatcaggtttgcaagtgagattgcaggagtagatgatctgggaacaacaggcaga
ggaaatgatatgcaagttggcacatatgttgaaaaaatgttcatgtctgaattatctggg
aatattattgatatctgccctgtaggtgccctaacctctaagccctatgcctttactgca
cggccttgggaaacaagaaagacagaatccattgatgtaatggatgcagttggaagtaat
attgtggttagcacaagaactggagaggtaatgagaattttgccacgaatgcatgaggac
atcaatgaagaatggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agacttaccgagccgatggtcagaaacgaaaagggacttttaagctatacttcctgggaa
gatgcactctctcgtgtagctggaatgttgcagagttttcaaggcaagaatgtggcagca
gttgcaggtggcttggtagatgctgaagccctagtagctctgaaagatttgcttaataga
gtggactctgaaaccttatgcactgaagaggtcttccccactgcaggagctggcacagat
ttgcgttccaattatcttcttaatactacaattgctggtgtagaagaggcaggtgttgtc
cttctggttggtacaaatccacgttttgaggcaccactatttaatgctagaattcgaaag
agctggcttcataatgacttgaaagtagcgcttataggtagtccagtggacctcacttac
cgatatgaccacctgggagactcccctaaaattctgcaagacattgcttccggtagccat
tcattcagccaggtcttaaaggatgctaaaaaaccaatggtgattttaggcagttctgca
ctccaaagaaatgatggggcagcaattcttgcagctgtttctagcatcgcacaaacgatt
cgggtgactggtggtgttgctgatgattggaaagttatgaatattcttcatagggttgca
agccaagtagctgctttggacctagggtataaacctggggtagaagcaattcggaagaac
cctcccaaagtgttgtttctcctgggagctgatggaggttgtatcacacgacaggattta
ccaaaggattgtttcattgtatatcaaggacatcatggtgatgttggagcacccatagct
gatgttattctcccaggagctgcttacacagaaaagtctgctacttatgtaaatactgag
ggtagagctcagcaaacaaaagtagcagtgacacctcctggcttggcacgagaggactgg
aaaattatcagagccctttctgagattgcaggcattactcttccatatgatactctggat
caagtgaggaacagattggaagaagtctctcctaatcttgttcgatatgatgatgtggaa
ggagctaattactttcagcaagcaaatgagctctccaagcttgtgaaccagcaacttctt
gctgatccccttgttccacctcaactaactataaaagacttctatatgacagattcaatt
agcagagcctcacagacaatggctaaatgtgtcaaagctgtcacagagggtgctcaagca
gtagaggaaccatccatatgctga
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