Marmota marmota marmota (Alpine marmot): 107139238
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Entry
107139238 CDS
T09644
Symbol
Pdgfra
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma01521
EGFR tyrosine kinase inhibitor resistance
mmma04010
MAPK signaling pathway
mmma04014
Ras signaling pathway
mmma04015
Rap1 signaling pathway
mmma04020
Calcium signaling pathway
mmma04072
Phospholipase D signaling pathway
mmma04144
Endocytosis
mmma04151
PI3K-Akt signaling pathway
mmma04510
Focal adhesion
mmma04540
Gap junction
mmma04630
JAK-STAT signaling pathway
mmma04810
Regulation of actin cytoskeleton
mmma05163
Human cytomegalovirus infection
mmma05200
Pathways in cancer
mmma05206
MicroRNAs in cancer
mmma05214
Glioma
mmma05215
Prostate cancer
mmma05218
Melanoma
mmma05230
Central carbon metabolism in cancer
mmma05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
107139238 (Pdgfra)
04014 Ras signaling pathway
107139238 (Pdgfra)
04015 Rap1 signaling pathway
107139238 (Pdgfra)
04630 JAK-STAT signaling pathway
107139238 (Pdgfra)
04020 Calcium signaling pathway
107139238 (Pdgfra)
04072 Phospholipase D signaling pathway
107139238 (Pdgfra)
04151 PI3K-Akt signaling pathway
107139238 (Pdgfra)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
107139238 (Pdgfra)
09144 Cellular community - eukaryotes
04510 Focal adhesion
107139238 (Pdgfra)
04540 Gap junction
107139238 (Pdgfra)
09142 Cell motility
04810 Regulation of actin cytoskeleton
107139238 (Pdgfra)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107139238 (Pdgfra)
05206 MicroRNAs in cancer
107139238 (Pdgfra)
05230 Central carbon metabolism in cancer
107139238 (Pdgfra)
05231 Choline metabolism in cancer
107139238 (Pdgfra)
09162 Cancer: specific types
05214 Glioma
107139238 (Pdgfra)
05218 Melanoma
107139238 (Pdgfra)
05215 Prostate cancer
107139238 (Pdgfra)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
107139238 (Pdgfra)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107139238 (Pdgfra)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107139238 (Pdgfra)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mmma04090
]
107139238 (Pdgfra)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
107139238 (Pdgfra)
Protein kinases [BR:
mmma01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
107139238 (Pdgfra)
CD molecules [BR:
mmma04090
]
Proteins
107139238 (Pdgfra)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
107139238
NCBI-ProteinID:
XP_015337602
Ensembl:
ENSMMMG00000020466
UniProt:
A0A8C6EXJ4
LinkDB
All DBs
Position
Unknown
AA seq
1089 aa
AA seq
DB search
MGTSHQAFLVFGCLLTGPGLILCQLSLPSILPNENEKVVQLNASFSLRCFGESEVSWQYP
MSEEENPNVEIIDEENNSGLFVTVLEVASASAAHTGLYTCYYNHTQTEESEIEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVVLRNSEGLVPASYDSKQGFNG
TFSVGPYICEATVKGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGVTMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFVEIKPTFGQLEAVNLHEVRHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIIVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSSGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTVLANNVSNIITEIYPRG
KSTVEGRVTFAKVEETIAVRCLAKNLLGSGNRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccatcaggccttcctggtcttcggctgtctcctcacagggccgggccta
atcctctgccagctttcattaccctccatccttccaaatgagaatgaaaaggttgtgcag
ctgaatgcatccttttctctgcggtgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcatagatgaagagaacaacagtggcctt
tttgtgacagtgctggaagtggccagtgcctcggcggcccacactggcttgtacacttgc
tattacaaccacactcagacagaagaaagcgagattgaaggcaggcacatttacatctat
gtgccagacccggatgtggcctttgtgcctctagggatgacagattatttagtcatcgtg
gaagatgatgattctgccatcataccctgtcgtaccacagacccggagactcctgtggtc
ttacgcaacagcgagggactggtgcctgcctcctatgacagcaaacagggcttcaatggg
accttcagtgtggggccctacatctgtgaggccactgtaaaagggaagaagttccagacc
ataccctttaacgtttatgctttgaaagcaacatcagaactggatctagaaatggaggct
ctgaaaactgtgtataagtcaggagaaacgatcgtggttacctgcgctgtttttaacaat
gaggtggtcgacctgcagtggacttaccctggagaagtgaaaggcaaaggagtcacgatg
ctggaggaaatcaaagtcccatccatcaaattggtgtacacattgacagtccctgaggcc
acggtgaaagacagtggagattatgaatgtgctgcccgacaggccaccaaggaggtcaaa
gaaatgaagaaagtcaccatttctgtccatgagaaagggtttgttgaaatcaaacccacc
tttggccagttggaagctgtcaacctgcatgaagtcagacattttgtggtggacgtgcag
gcctaccctcctcccaggatatcttggctgaaggacaacctgactctgattgaaaatctc
actgagatcaccactgatgtggaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgctaaggaagaagatagtggccattatactataatagttcaaaatgaagat
gatgtgaagagctatacttttgaactattgactcaagttccatcctctatcctggatttg
gtcgacgaccatcatggctccagcggaggacagactgtgaggtgcacggctgagggcaca
cctcttcccgacattgagtggatgatttgcaaggatattaaaaaatgtaataatgaaacc
tcatggacagtcttagccaacaatgtctcaaatatcatcacagagatctaccctcgaggc
aagagtaccgtggagggccgagtgacatttgccaaagtagaggagaccattgcagttcga
tgcctggctaagaatctccttggttctgggaaccgagagctgaagctggtggctcccacc
ctgcgttctgagcttacggtggcagctgcagtcctggtgctgttggtgattgtgatcatc
tcacttattgtcctggttgtcatttggaaacagaaaccaaggtatgaaattcgctggagg
gtcattgaatcaatcagccccgatggacatgaatatatttatgtggacccgatgcagcta
ccttatgactcgagatgggaatttccaagagatggactagtgcttggtcgcatcttggga
tctggtgcatttgggaaagtggttgaaggaacagcctatggattaagccggtcccagcct
gttatgaaagtagccgtgaagatgctcaaacccactgccaggtccagtgaaaaacaagct
ctcatgtctgagctgaagataatgactcacctggggccccatttaaacattgtcaacttg
ctgggagcctgtactaagtcaggccccatctacatcatcactgagtactgtttctatggg
gatctggtcaactatttgcataagaatagggatagcttcctgagccgccacccagagaag
ccaaagaaagagctggacatctttggattgaaccctgctgatgagagcacacgcagttat
gtgattctatcttttgagaacaatggtgattacatggacatgaagcaagccgacaccaca
cagtacgtccccatgctggaaaggaaagaggtctccaagtattcggacatccagagatca
ctgtacgatcgcccggcctcgtataagaagaaatctatgttagactcagaagtcaaaaac
ctcctttcagatgacaactcagaaggccttactttgttggatttgttgagcttcacctat
caagttgcccgaggaatggagtttttggcttccaaaaattgtgtccaccgggacctggct
gctcgcaatgtcctcctagcacaagggaagattgtgaagatctgtgactttggcctggcc
agggacatcatgcacgattcgaactacgtgtcgaaaggcagtaccttccttcctgtgaag
tggatggctcctgagagcatctttgacaacctctacaccacgctgagcgatgtctggtct
tatgggattctgctctgggagatcttttctcttggtggcacaccctaccctggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaaacctgaccat
gccaccagtgaagtctatgagatcatggtgcagtgctggaacagtgagccagagaagaga
ccctccttctaccacctgagcgagatagtggagaatcttctgcctggacaatataaaaag
agttatgaaaaaattcacctggacttcctgaagagtgaccatcccgctgtggcacgcatg
cgtgtggactcggacaatgcatacattggcgtcacctacaaaaatgaggaagacaagctg
aaggactgggaaggtggcctggacgagcagagactgagcgcagacagtggctacatcatc
cctctgcctgacatcgaccctgttcctgaggaggaagacctgggcaagaggaacagacac
agctcacagacctctgaagagagtgccattgagacaggttccagcagctccaccttcatc
aagagagaggacgagaccattgaggacatcgacatgatggacgacattggcatagactcc
tcagacctggtggaggacagcttcctgtaa
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integrated database retrieval system
