Marmota marmota marmota (Alpine marmot): 107139600
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Entry
107139600 CDS
T09644
Symbol
Rock1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma04022
cGMP-PKG signaling pathway
mmma04024
cAMP signaling pathway
mmma04062
Chemokine signaling pathway
mmma04071
Sphingolipid signaling pathway
mmma04270
Vascular smooth muscle contraction
mmma04350
TGF-beta signaling pathway
mmma04360
Axon guidance
mmma04510
Focal adhesion
mmma04520
Adherens junction
mmma04530
Tight junction
mmma04611
Platelet activation
mmma04670
Leukocyte transendothelial migration
mmma04810
Regulation of actin cytoskeleton
mmma04921
Oxytocin signaling pathway
mmma05135
Yersinia infection
mmma05163
Human cytomegalovirus infection
mmma05200
Pathways in cancer
mmma05205
Proteoglycans in cancer
mmma05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
107139600 (Rock1)
04071 Sphingolipid signaling pathway
107139600 (Rock1)
04024 cAMP signaling pathway
107139600 (Rock1)
04022 cGMP-PKG signaling pathway
107139600 (Rock1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
107139600 (Rock1)
04520 Adherens junction
107139600 (Rock1)
04530 Tight junction
107139600 (Rock1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
107139600 (Rock1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
107139600 (Rock1)
04670 Leukocyte transendothelial migration
107139600 (Rock1)
04062 Chemokine signaling pathway
107139600 (Rock1)
09152 Endocrine system
04921 Oxytocin signaling pathway
107139600 (Rock1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
107139600 (Rock1)
09158 Development and regeneration
04360 Axon guidance
107139600 (Rock1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107139600 (Rock1)
05206 MicroRNAs in cancer
107139600 (Rock1)
05205 Proteoglycans in cancer
107139600 (Rock1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
107139600 (Rock1)
09171 Infectious disease: bacterial
05135 Yersinia infection
107139600 (Rock1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107139600 (Rock1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmma03036
]
107139600 (Rock1)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
107139600 (Rock1)
Protein kinases [BR:
mmma01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
107139600 (Rock1)
Chromosome and associated proteins [BR:
mmma03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
107139600 (Rock1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
107139600
NCBI-ProteinID:
XP_015337984
Ensembl:
ENSMMMG00000010370
LinkDB
All DBs
Position
Unknown
AA seq
1354 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEDDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLPSANPNDNRTSSNV
DKSLQESLQKTIYKLEEQLHNEIQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLTNEKL
IQLQKQLEEANDLLRTESDTAVRLRKSHTEMSISISQLESLNRELQERNRILENSKSQTD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLSTQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHAVSRLEETNSMLTKDIELLRKENE
ELTDKMRKAEEEYKLKKEEEINNLKATFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctacgggat
cccaagtcggaagtgaattcggattgtttgttggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatctacgaggaag
gtatatgctatgaagcttctcagcaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaacagtccttgggttgttcagcttttt
tatgcattccaagatgatcgctatctctacatggtgatggaatatatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaagtgggcacgattctatactgca
gaagtggttcttgcgttggatgcaatccattccatgggttttattcatagggatgtgaaa
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattat
atttcccctgaagtattaaaatcccaaggtggtgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctttggttggaacttacagtaagattatgaaccataaaaattcactaacttttcct
gatgataatgacatatcaaaagaagcaaaaaatctcatttgtgccttccttactgacaga
gaagtgagattaggaagaaatggtgtagaagaaatcaaacgacatctgttcttcaaaaat
gatcagtgggcttgggaaacactccgagacactgtagcaccagttgtacctgatttaagt
agtgacattgatactagtaattttgatgacttagaagatgataaaggagatgaagaaaca
ttccctattcctaaagcttttgttggcaatcaactaccttttgtaggatttacatattat
agcaatcgtagatacttaccttctgcaaatcctaatgataacagaaccagttccaatgtg
gataaaagcttgcaggaaagtttgcaaaaaacaatttataagctagaagaacagctgcat
aatgaaatacagttaaaagatgaaatggagcagaagtgcagaacttcaaatataaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaatctagaatctaca
gtgtctcaaattgagaaggaaaaaatgttgctacaacatagaattaatgagtaccaaaga
aaagctgaacaggaaaatgaaaagagaagaaatgtagaaaatgaagtttctacattaaaa
gatcagttggaagacttaaagaaagtaagtcagaattcacagcttacaaatgagaagctg
atacaattacaaaagcagctagaagaagccaatgacttgcttaggacagagtcagacaca
gctgtaagattaaggaagagtcatacagagatgagcatatcaattagccagctagagtcc
ctgaacagagaattgcaggagagaaacagaattttagagaattccaagtcacaaacagac
aaggattactaccagctacaagctgtattggaagctgaacgaagagacagaggtcatgat
tctgaaatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggagggagaaagaaaagaggctcaagacatgcttaat
cattcagaaaaggaaaagaataatttagagatagatttaaactacaagcttaaatcattg
caacaaaggttagaacaagaggtaaatgaacacaaagtaaccaaagctcgtttaactgat
aaacatcagtctattgaagaggcaaagtctgttgcaatgtgtgagatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacaa
tgttctatgttagatgttgatctgaaacaatctcagcagaagctggaacatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctaagcctgcaattagagcaagaatcc
aataagcgactgttgttacaaaatgaattgaagactcaagcatttgaggcagataattta
aaaggtttagaaaagcagatgaaacaagaaataaatactttattggaagcaaagagatta
ttagaatttgagttagctcagcttacaaaacagtatagaggaaatgaaggacaaatgcgg
gagctacaagatcagcttgaagctgaacaatatttctcaacactttataaaacccaggta
aaggaacttaaagaagaaattgaagaaaaaaacagagaaaatttaaagaagatacaagaa
ctacaaaatgaaaaagaaaccctttctactcagttggatctagcagaaacaaaagctgag
tctgagcaattggctcgaggacttctggaagaacagtattttgaattgacccaagaaagc
aagaaagctgcttcaagaaatagacaagagatcacagataaagatcacgctgttagtcgg
cttgaagaaacgaacagcatgctaaccaaagatattgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggaaggcagaggaagaatataaattgaagaaggaggaggag
atcaataatcttaaggctacttttgagaagaatatcaatacagaacgaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcgcaaagattttaaaattgatagaaag
aaagctaatactcaagatttgagaaagaaagagaaggaaaatcggaagctacaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactcaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgaacttcagatgcagttg
gctagcaaagagagtgatattgaacaattacgagctaaacttttggatctttcggattct
actagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagaatcaaga
attgaaggttggctttctgtaccaaatagaggaaatatcaaaagatatggctggaagaaa
cagtatgttgtcgtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccatctatggtattggacatagataagctgtttcatgttcgacctgtaact
caaggagatgtgtacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgttgagatggaaccagtacagcaagctgaaaaa
actaatttccaaaatcacaaaggccatgagttcattcctaccctctaccactttcctgcc
aattgtgaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctagag
tgtcgaagatgccatgttaagtgccacagagatcatttagataagaaagaagacttaatt
tctccgtgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaactcatttagtaaagaagatccctaaaaatcca
ccatctggttttgttcgtgcctcacctcgaacactttctacaagatccactgcaaatcag
tctttccggaaagtggtcaaaaatacatctggaaaaactagttaa
DBGET
integrated database retrieval system