KEGG   Marmota marmota marmota (Alpine marmot): 107139600
Entry
107139600         CDS       T09644                                 
Symbol
Rock1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma04022  cGMP-PKG signaling pathway
mmma04024  cAMP signaling pathway
mmma04062  Chemokine signaling pathway
mmma04071  Sphingolipid signaling pathway
mmma04270  Vascular smooth muscle contraction
mmma04350  TGF-beta signaling pathway
mmma04360  Axon guidance
mmma04510  Focal adhesion
mmma04520  Adherens junction
mmma04530  Tight junction
mmma04611  Platelet activation
mmma04670  Leukocyte transendothelial migration
mmma04810  Regulation of actin cytoskeleton
mmma04921  Oxytocin signaling pathway
mmma05135  Yersinia infection
mmma05163  Human cytomegalovirus infection
mmma05200  Pathways in cancer
mmma05205  Proteoglycans in cancer
mmma05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    107139600 (Rock1)
   04071 Sphingolipid signaling pathway
    107139600 (Rock1)
   04024 cAMP signaling pathway
    107139600 (Rock1)
   04022 cGMP-PKG signaling pathway
    107139600 (Rock1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    107139600 (Rock1)
   04520 Adherens junction
    107139600 (Rock1)
   04530 Tight junction
    107139600 (Rock1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107139600 (Rock1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    107139600 (Rock1)
   04670 Leukocyte transendothelial migration
    107139600 (Rock1)
   04062 Chemokine signaling pathway
    107139600 (Rock1)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    107139600 (Rock1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    107139600 (Rock1)
  09158 Development and regeneration
   04360 Axon guidance
    107139600 (Rock1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107139600 (Rock1)
   05206 MicroRNAs in cancer
    107139600 (Rock1)
   05205 Proteoglycans in cancer
    107139600 (Rock1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    107139600 (Rock1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    107139600 (Rock1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmma01001]
    107139600 (Rock1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmma03036]
    107139600 (Rock1)
Enzymes [BR:mmma01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     107139600 (Rock1)
Protein kinases [BR:mmma01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   107139600 (Rock1)
Chromosome and associated proteins [BR:mmma03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    107139600 (Rock1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Pkinase_C APH
Other DBs
NCBI-GeneID: 107139600
NCBI-ProteinID: XP_015337984
Ensembl: ENSMMMG00000010370
LinkDB
Position
Unknown
AA seq 1354 aa
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEDDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLPSANPNDNRTSSNV
DKSLQESLQKTIYKLEEQLHNEIQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLTNEKL
IQLQKQLEEANDLLRTESDTAVRLRKSHTEMSISISQLESLNRELQERNRILENSKSQTD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLSTQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHAVSRLEETNSMLTKDIELLRKENE
ELTDKMRKAEEEYKLKKEEEINNLKATFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq 4065 nt   +upstreamnt  +downstreamnt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctacgggat
cccaagtcggaagtgaattcggattgtttgttggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatctacgaggaag
gtatatgctatgaagcttctcagcaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaacagtccttgggttgttcagcttttt
tatgcattccaagatgatcgctatctctacatggtgatggaatatatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaagtgggcacgattctatactgca
gaagtggttcttgcgttggatgcaatccattccatgggttttattcatagggatgtgaaa
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattat
atttcccctgaagtattaaaatcccaaggtggtgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctttggttggaacttacagtaagattatgaaccataaaaattcactaacttttcct
gatgataatgacatatcaaaagaagcaaaaaatctcatttgtgccttccttactgacaga
gaagtgagattaggaagaaatggtgtagaagaaatcaaacgacatctgttcttcaaaaat
gatcagtgggcttgggaaacactccgagacactgtagcaccagttgtacctgatttaagt
agtgacattgatactagtaattttgatgacttagaagatgataaaggagatgaagaaaca
ttccctattcctaaagcttttgttggcaatcaactaccttttgtaggatttacatattat
agcaatcgtagatacttaccttctgcaaatcctaatgataacagaaccagttccaatgtg
gataaaagcttgcaggaaagtttgcaaaaaacaatttataagctagaagaacagctgcat
aatgaaatacagttaaaagatgaaatggagcagaagtgcagaacttcaaatataaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaatctagaatctaca
gtgtctcaaattgagaaggaaaaaatgttgctacaacatagaattaatgagtaccaaaga
aaagctgaacaggaaaatgaaaagagaagaaatgtagaaaatgaagtttctacattaaaa
gatcagttggaagacttaaagaaagtaagtcagaattcacagcttacaaatgagaagctg
atacaattacaaaagcagctagaagaagccaatgacttgcttaggacagagtcagacaca
gctgtaagattaaggaagagtcatacagagatgagcatatcaattagccagctagagtcc
ctgaacagagaattgcaggagagaaacagaattttagagaattccaagtcacaaacagac
aaggattactaccagctacaagctgtattggaagctgaacgaagagacagaggtcatgat
tctgaaatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggagggagaaagaaaagaggctcaagacatgcttaat
cattcagaaaaggaaaagaataatttagagatagatttaaactacaagcttaaatcattg
caacaaaggttagaacaagaggtaaatgaacacaaagtaaccaaagctcgtttaactgat
aaacatcagtctattgaagaggcaaagtctgttgcaatgtgtgagatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacaa
tgttctatgttagatgttgatctgaaacaatctcagcagaagctggaacatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctaagcctgcaattagagcaagaatcc
aataagcgactgttgttacaaaatgaattgaagactcaagcatttgaggcagataattta
aaaggtttagaaaagcagatgaaacaagaaataaatactttattggaagcaaagagatta
ttagaatttgagttagctcagcttacaaaacagtatagaggaaatgaaggacaaatgcgg
gagctacaagatcagcttgaagctgaacaatatttctcaacactttataaaacccaggta
aaggaacttaaagaagaaattgaagaaaaaaacagagaaaatttaaagaagatacaagaa
ctacaaaatgaaaaagaaaccctttctactcagttggatctagcagaaacaaaagctgag
tctgagcaattggctcgaggacttctggaagaacagtattttgaattgacccaagaaagc
aagaaagctgcttcaagaaatagacaagagatcacagataaagatcacgctgttagtcgg
cttgaagaaacgaacagcatgctaaccaaagatattgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggaaggcagaggaagaatataaattgaagaaggaggaggag
atcaataatcttaaggctacttttgagaagaatatcaatacagaacgaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcgcaaagattttaaaattgatagaaag
aaagctaatactcaagatttgagaaagaaagagaaggaaaatcggaagctacaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactcaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgaacttcagatgcagttg
gctagcaaagagagtgatattgaacaattacgagctaaacttttggatctttcggattct
actagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagaatcaaga
attgaaggttggctttctgtaccaaatagaggaaatatcaaaagatatggctggaagaaa
cagtatgttgtcgtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccatctatggtattggacatagataagctgtttcatgttcgacctgtaact
caaggagatgtgtacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgttgagatggaaccagtacagcaagctgaaaaa
actaatttccaaaatcacaaaggccatgagttcattcctaccctctaccactttcctgcc
aattgtgaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctagag
tgtcgaagatgccatgttaagtgccacagagatcatttagataagaaagaagacttaatt
tctccgtgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaactcatttagtaaagaagatccctaaaaatcca
ccatctggttttgttcgtgcctcacctcgaacactttctacaagatccactgcaaatcag
tctttccggaaagtggtcaaaaatacatctggaaaaactagttaa

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