KEGG   Marmota marmota marmota (Alpine marmot): 107141352
Entry
107141352         CDS       T09644                                 
Symbol
Nfkb1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma01523  Antifolate resistance
mmma04010  MAPK signaling pathway
mmma04014  Ras signaling pathway
mmma04024  cAMP signaling pathway
mmma04062  Chemokine signaling pathway
mmma04064  NF-kappa B signaling pathway
mmma04066  HIF-1 signaling pathway
mmma04071  Sphingolipid signaling pathway
mmma04151  PI3K-Akt signaling pathway
mmma04210  Apoptosis
mmma04211  Longevity regulating pathway
mmma04218  Cellular senescence
mmma04380  Osteoclast differentiation
mmma04613  Neutrophil extracellular trap formation
mmma04620  Toll-like receptor signaling pathway
mmma04621  NOD-like receptor signaling pathway
mmma04622  RIG-I-like receptor signaling pathway
mmma04623  Cytosolic DNA-sensing pathway
mmma04625  C-type lectin receptor signaling pathway
mmma04657  IL-17 signaling pathway
mmma04658  Th1 and Th2 cell differentiation
mmma04659  Th17 cell differentiation
mmma04660  T cell receptor signaling pathway
mmma04662  B cell receptor signaling pathway
mmma04668  TNF signaling pathway
mmma04722  Neurotrophin signaling pathway
mmma04917  Prolactin signaling pathway
mmma04920  Adipocytokine signaling pathway
mmma04926  Relaxin signaling pathway
mmma04931  Insulin resistance
mmma04932  Non-alcoholic fatty liver disease
mmma04933  AGE-RAGE signaling pathway in diabetic complications
mmma04936  Alcoholic liver disease
mmma05010  Alzheimer disease
mmma05022  Pathways of neurodegeneration - multiple diseases
mmma05030  Cocaine addiction
mmma05132  Salmonella infection
mmma05133  Pertussis
mmma05134  Legionellosis
mmma05135  Yersinia infection
mmma05140  Leishmaniasis
mmma05142  Chagas disease
mmma05145  Toxoplasmosis
mmma05146  Amoebiasis
mmma05152  Tuberculosis
mmma05160  Hepatitis C
mmma05161  Hepatitis B
mmma05162  Measles
mmma05163  Human cytomegalovirus infection
mmma05164  Influenza A
mmma05165  Human papillomavirus infection
mmma05166  Human T-cell leukemia virus 1 infection
mmma05167  Kaposi sarcoma-associated herpesvirus infection
mmma05168  Herpes simplex virus 1 infection
mmma05169  Epstein-Barr virus infection
mmma05170  Human immunodeficiency virus 1 infection
mmma05171  Coronavirus disease - COVID-19
mmma05200  Pathways in cancer
mmma05202  Transcriptional misregulation in cancer
mmma05203  Viral carcinogenesis
mmma05206  MicroRNAs in cancer
mmma05207  Chemical carcinogenesis - receptor activation
mmma05208  Chemical carcinogenesis - reactive oxygen species
mmma05212  Pancreatic cancer
mmma05215  Prostate cancer
mmma05220  Chronic myeloid leukemia
mmma05221  Acute myeloid leukemia
mmma05222  Small cell lung cancer
mmma05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmma05321  Inflammatory bowel disease
mmma05415  Diabetic cardiomyopathy
mmma05417  Lipid and atherosclerosis
mmma05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107141352 (Nfkb1)
   04014 Ras signaling pathway
    107141352 (Nfkb1)
   04064 NF-kappa B signaling pathway
    107141352 (Nfkb1)
   04668 TNF signaling pathway
    107141352 (Nfkb1)
   04066 HIF-1 signaling pathway
    107141352 (Nfkb1)
   04071 Sphingolipid signaling pathway
    107141352 (Nfkb1)
   04024 cAMP signaling pathway
    107141352 (Nfkb1)
   04151 PI3K-Akt signaling pathway
    107141352 (Nfkb1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    107141352 (Nfkb1)
   04218 Cellular senescence
    107141352 (Nfkb1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    107141352 (Nfkb1)
   04620 Toll-like receptor signaling pathway
    107141352 (Nfkb1)
   04621 NOD-like receptor signaling pathway
    107141352 (Nfkb1)
   04622 RIG-I-like receptor signaling pathway
    107141352 (Nfkb1)
   04623 Cytosolic DNA-sensing pathway
    107141352 (Nfkb1)
   04625 C-type lectin receptor signaling pathway
    107141352 (Nfkb1)
   04660 T cell receptor signaling pathway
    107141352 (Nfkb1)
   04658 Th1 and Th2 cell differentiation
    107141352 (Nfkb1)
   04659 Th17 cell differentiation
    107141352 (Nfkb1)
   04657 IL-17 signaling pathway
    107141352 (Nfkb1)
   04662 B cell receptor signaling pathway
    107141352 (Nfkb1)
   04062 Chemokine signaling pathway
    107141352 (Nfkb1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    107141352 (Nfkb1)
   04917 Prolactin signaling pathway
    107141352 (Nfkb1)
   04926 Relaxin signaling pathway
    107141352 (Nfkb1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    107141352 (Nfkb1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    107141352 (Nfkb1)
  09149 Aging
   04211 Longevity regulating pathway
    107141352 (Nfkb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107141352 (Nfkb1)
   05202 Transcriptional misregulation in cancer
    107141352 (Nfkb1)
   05206 MicroRNAs in cancer
    107141352 (Nfkb1)
   05207 Chemical carcinogenesis - receptor activation
    107141352 (Nfkb1)
   05208 Chemical carcinogenesis - reactive oxygen species
    107141352 (Nfkb1)
   05203 Viral carcinogenesis
    107141352 (Nfkb1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    107141352 (Nfkb1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    107141352 (Nfkb1)
   05221 Acute myeloid leukemia
    107141352 (Nfkb1)
   05220 Chronic myeloid leukemia
    107141352 (Nfkb1)
   05215 Prostate cancer
    107141352 (Nfkb1)
   05222 Small cell lung cancer
    107141352 (Nfkb1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    107141352 (Nfkb1)
   05170 Human immunodeficiency virus 1 infection
    107141352 (Nfkb1)
   05161 Hepatitis B
    107141352 (Nfkb1)
   05160 Hepatitis C
    107141352 (Nfkb1)
   05171 Coronavirus disease - COVID-19
    107141352 (Nfkb1)
   05164 Influenza A
    107141352 (Nfkb1)
   05162 Measles
    107141352 (Nfkb1)
   05168 Herpes simplex virus 1 infection
    107141352 (Nfkb1)
   05163 Human cytomegalovirus infection
    107141352 (Nfkb1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    107141352 (Nfkb1)
   05169 Epstein-Barr virus infection
    107141352 (Nfkb1)
   05165 Human papillomavirus infection
    107141352 (Nfkb1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    107141352 (Nfkb1)
   05135 Yersinia infection
    107141352 (Nfkb1)
   05133 Pertussis
    107141352 (Nfkb1)
   05134 Legionellosis
    107141352 (Nfkb1)
   05152 Tuberculosis
    107141352 (Nfkb1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    107141352 (Nfkb1)
   05145 Toxoplasmosis
    107141352 (Nfkb1)
   05140 Leishmaniasis
    107141352 (Nfkb1)
   05142 Chagas disease
    107141352 (Nfkb1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    107141352 (Nfkb1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107141352 (Nfkb1)
   05022 Pathways of neurodegeneration - multiple diseases
    107141352 (Nfkb1)
  09165 Substance dependence
   05030 Cocaine addiction
    107141352 (Nfkb1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    107141352 (Nfkb1)
   05418 Fluid shear stress and atherosclerosis
    107141352 (Nfkb1)
   05415 Diabetic cardiomyopathy
    107141352 (Nfkb1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    107141352 (Nfkb1)
   04932 Non-alcoholic fatty liver disease
    107141352 (Nfkb1)
   04931 Insulin resistance
    107141352 (Nfkb1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    107141352 (Nfkb1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    107141352 (Nfkb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmma03000]
    107141352 (Nfkb1)
Transcription factors [BR:mmma03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    107141352 (Nfkb1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 107141352
NCBI-ProteinID: XP_015340088
Ensembl: ENSMMMG00000008676
LinkDB
Position
Unknown
AA seq 973 aa
MAGNNPYGGMPEQIFHLNPLPHTIFNPELFPPEMPLPTADGPYLQILEQPKQRGFRFRYV
CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED
GICTVNAGPKDMVVGFANLGILHVTKKKVFETLEARMTDACVRGYNPGLLVHPDLAYLQA
EGGGDRQLTDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY
DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDF
SPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ
RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGSTGSTGPGYGFPHYGFPTYGGITFH
PGTTKSNAGLKHGTMNDVSKSDPEDCGKSGGREIVNLSGNIIKTTEQDKLGMSIDGNEEV
MLPCTMGVKQEDSPFQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLAAVQDE
NGDSVLHLAIIHLHAQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDL
LSAGADLSLLDRLGNSVLHLAAKEGHDKVLSVLLKHKKAALLIDRPNGEGLNAIHIAVMS
NSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTT
PLHIAAGRGSTKLAALLKAAGADPLVENFEPLYDLDDSWEKAGEDEGVVPGTTPLDMAAN
WQVFDILNGKPYEPEFTSEDLLAQGDMKQLTEDAKLQLYKLLEIPDPDKNWATLAQKLGL
GILNNAFRLSPAPSKTLMDNYEVSGGTIKELVEALRQMGYTEAIEVIQAAFCTSEASSPV
KTTSQAHSLPFLPSSTRQQIDELRDNDSICDSGVETSFRKLSFTESLTSSSSLLTLNKMP
HDYGQEGPIEGKI
NT seq 2922 nt   +upstreamnt  +downstreamnt
atggcaggaaacaatccatatgggggaatgcctgaacaaatatttcatttgaatcctttg
cctcatactatatttaatccagaattatttcccccagagatgccactgcctacagcagat
ggcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttatgtt
tgtgaaggcccatcccatggcggacttcctggtgcatctagtgagaagaacaagaagtcc
taccctcaggtcaaaatctgcaactatgtgggacctgcaaaggttattgttcagttggtc
acaaatgggaaaaatatccacctgcacgcccacagcctggtgggaaaacactgtgaggat
ggaatctgcactgtgaatgccggacccaaggacatggtggtcggctttgcaaacctgggt
atacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgacagacgcg
tgtgtaaggggctacaatccgggacttctagtgcatcctgaccttgcgtatttgcaagca
gagggtggaggagaccggcagctcacagatcgggaaaaggagctcatccgccaggcggct
cttcagcagactaaggagatggacctcagcgtggtgcggctcatgtttacagcttttctt
cccgacagcaccggcagcttcaccaggcgcctggaacccgtggtgtcagacgccatctat
gacagcaaagcccccaatgcatccaatttgaaaattgtaagaatggacaggacagctgga
tgtgtaactggaggggaagaaatttatcttctctgtgacaaagttcagaaagatgatatc
cagattcggttttatgaagaggaggaaaatggtggagtttgggaaggatttggagatttt
tcccccacagatgttcatagacaattcgccatcgtcttcaaaactccaaagtataaagat
gtcaacattacaaagccagcctctgtctttgtccagcttcggagaaaatctgatttggaa
actagtgaaccaaaaccttttctctactaccctgaaatcaaagataaagaggaagtgcag
aggaaacggcagaagctcatgcccaatttttcggatagtttcggcggcggcagtggtgcc
ggggctggaggtggaggcatgttcggtagcggcggtggaggagggagcactggaagtacg
ggtccagggtacggcttcccgcactatggatttcctacatacggtggaattaccttccac
cctggaaccactaaatccaatgctgggctgaagcatggaaccatgaatgatgtatctaaa
agtgatcctgaagattgtggcaagagtggtggcagagagattgtaaatctttctgggaac
attatcaaaaccacagaacaagataaactgggcatgtccattgacggaaatgaggaggtg
atgctgccgtgcaccatgggggtaaagcaagaggactctccgtttcaggataacctcttt
ctggagaaggctatgcagcttgccaagcggcacgccaacgcccttttcgactacgcggtg
acgggagatgtgaagatgctgctggcggtccagcggcatctcgctgcagtgcaggatgag
aatggggacagtgtcttacacttagccatcatccaccttcatgctcagcttgtgagagat
ctgctagaagttacatctggtttgatttctgatgacattatcaacatgagaaatgatctg
taccagacgcccttgcacttggcagtgatcactaagcaagaagatgtggtagaggacttg
ctgagtgccggggctgacctgagccttctggaccgcttgggtaactctgttttgcaccta
gctgccaaagaaggacatgataaagttctcagtgtcttactcaagcacaaaaaggcagca
ctacttatcgaccgtcccaacggggaaggtctgaatgccattcacatagctgtgatgagc
aacagcctgccgtgtctgctgctgctggtggccgccggagcagacgtcaatgctcaggag
cagaagtccgggcgaacagcactgcacctggctgtggagcatgacaacatctccttggcg
ggctgcctgctcctggagggggatgcccacgtagacagtaccacctatgatggaactaca
cccctacacatcgcagccgggagagggtccaccaagctggcagctcttctaaaagcagca
ggagcagatccactggtggagaactttgagcctctttatgacctggatgactcttgggaa
aaggcaggagaggacgaaggggttgtgcctggaaccacacccctagacatggccgccaac
tggcaggtatttgacatcttaaatgggaagccctatgagccagagtttacatctgaggat
ttgctggcacaaggagacatgaaacagctgaccgaagatgcaaaactgcagctctacaag
ttgctagaaatccctgatccagacaaaaactgggctactctggcacagaagttaggtctg
gggatacttaataatgctttccggctgagtcctgctccttccaaaactctcatggacaac
tatgaggtctctggggggaccatcaaagagctggtagaggccctgagacagatgggctac
accgaagcaatcgaagtgatccaggctgccttctgcacctcggaagcctccagccccgtg
aagaccacctctcaggcccattcactgcctttcttgccttcctcaacaaggcagcaaata
gatgagcttcgagacaatgacagcatctgtgacagtggtgtggagacatccttccgcaaa
ctcagctttacagagtctctgaccagcagcagctcattgctaactctcaacaaaatgccc
cacgattatgggcaggaaggacctatagaaggcaaaatttag

DBGET integrated database retrieval system