Marmota marmota marmota (Alpine marmot): 107141689
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Entry
107141689 CDS
T09644
Symbol
Jak1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma01521
EGFR tyrosine kinase inhibitor resistance
mmma04151
PI3K-Akt signaling pathway
mmma04217
Necroptosis
mmma04380
Osteoclast differentiation
mmma04550
Signaling pathways regulating pluripotency of stem cells
mmma04620
Toll-like receptor signaling pathway
mmma04621
NOD-like receptor signaling pathway
mmma04630
JAK-STAT signaling pathway
mmma04658
Th1 and Th2 cell differentiation
mmma04659
Th17 cell differentiation
mmma05140
Leishmaniasis
mmma05145
Toxoplasmosis
mmma05152
Tuberculosis
mmma05160
Hepatitis C
mmma05161
Hepatitis B
mmma05162
Measles
mmma05163
Human cytomegalovirus infection
mmma05164
Influenza A
mmma05165
Human papillomavirus infection
mmma05166
Human T-cell leukemia virus 1 infection
mmma05167
Kaposi sarcoma-associated herpesvirus infection
mmma05168
Herpes simplex virus 1 infection
mmma05169
Epstein-Barr virus infection
mmma05171
Coronavirus disease
mmma05200
Pathways in cancer
mmma05203
Viral carcinogenesis
mmma05212
Pancreatic cancer
mmma05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
107141689 (Jak1)
04151 PI3K-Akt signaling pathway
107141689 (Jak1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
107141689 (Jak1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
107141689 (Jak1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
107141689 (Jak1)
04621 NOD-like receptor signaling pathway
107141689 (Jak1)
04658 Th1 and Th2 cell differentiation
107141689 (Jak1)
04659 Th17 cell differentiation
107141689 (Jak1)
09158 Development and regeneration
04380 Osteoclast differentiation
107141689 (Jak1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107141689 (Jak1)
05203 Viral carcinogenesis
107141689 (Jak1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
107141689 (Jak1)
09162 Cancer: specific types
05212 Pancreatic cancer
107141689 (Jak1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
107141689 (Jak1)
05161 Hepatitis B
107141689 (Jak1)
05160 Hepatitis C
107141689 (Jak1)
05171 Coronavirus disease
107141689 (Jak1)
05164 Influenza A
107141689 (Jak1)
05162 Measles
107141689 (Jak1)
05168 Herpes simplex virus 1 infection
107141689 (Jak1)
05163 Human cytomegalovirus infection
107141689 (Jak1)
05167 Kaposi sarcoma-associated herpesvirus infection
107141689 (Jak1)
05169 Epstein-Barr virus infection
107141689 (Jak1)
05165 Human papillomavirus infection
107141689 (Jak1)
09171 Infectious disease: bacterial
05152 Tuberculosis
107141689 (Jak1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
107141689 (Jak1)
05140 Leishmaniasis
107141689 (Jak1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107141689 (Jak1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107141689 (Jak1)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107141689 (Jak1)
Protein kinases [BR:
mmma01001
]
Non-receptor tyrosine kinases
JAK family [OT]
107141689 (Jak1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
107141689
NCBI-ProteinID:
XP_015340391
Ensembl:
ENSMMMG00000013495
UniProt:
A0A8C5ZI47
LinkDB
All DBs
Position
Unknown
AA seq
1157 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKAEVNQVAPEPGVEVTFYLPDREPLRLGSGEYTAEEL
CIRAAQECSISPLCHNLFALYDENTKLWYPPNRTITIDDKISLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKVQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSPHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WLHSNDSGNVLSYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIQ
EEWNNFSYFPEITHIVIKESMVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGNEEGMYVLRWSCTDFDNILMTVT
CFEKSEQVLGTHKQFKNFQIEVQKGRYSLHGSDRNFPTLEGLMSHLKKQILRTDNISFVL
KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGDHLGRGTRTHIYSG
TLVDYKDDEGAAEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
VENIMVEEYVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
LLAREGIDSEIGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDS
ESSPMALFLKMIGPTQGQMTVTRLVNTLKEGKRLPCPPNCPDKVYQLMRKCWELQPSNRT
TFQSLIEGFEALLKYEA
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaagactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaaggcggaggtgaatcaggtggcccctgagccaggggtggaagtgaccttc
tatctgccagacagggagcccctccggctgggcagtggagagtacacagcagaagagctg
tgcatcagggcagcgcaagaatgcagtatatctcctctatgccacaacctctttgccttg
tatgatgagaacaccaagctctggtatcctccgaaccgcaccatcaccattgatgacaag
atatcactccgactgcactaccgcatgaggttctacttcacaaactggcatggaaccaat
gacaatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaag
aaaaaggttccagatgcaacccctctccttgatgccagctcgctggagtacctgtttgct
cagggtcagtatgatttggtcaaatgcctggctcccattcgggaccccaagactgagcag
gatgggcatgatattgagaatgagtgcctggggatggctgtcctggccatttcgcactat
gccatgatgaagaaggtgcaattgccagaacttcccaaggacatcagctacaagcgatat
attccagaaacattgaataaatccatcagacagaggaaccttctcaccaggatgaggata
aataatgttttcaaggatttcctaaaggaatttaataacaagaccatttgtgacagcagt
gtgtcccctcatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggggctgaaatatttgagacttctatgttattaatttcatcagaaaatgaaatgaat
tggcttcattcaaatgacagtggaaatgttctctcttatgaagtgatggtaactggaaat
cttggaatccagtggcggcagaaaccaaacgttgttccggttgaaaaggaaaaaaataaa
ctgaagcggaaaaaactggaaaataaacacaagaaggatgaggagaaaaataaaatccag
gaagaatggaacaatttttcttatttccctgaaatcactcacattgtaatcaaggagtct
atggtcagcattaataagcaggacaacaaaaaaatggaactgaagctttcttcccatgag
gaggccttgtcctttgtgtccctggttgatggctacttccggctcacagcagatgcccat
cattacctctgcaccgatgtagctcccccattgatagtccacaacatacagaatggctgc
catggtccaatctgcacagaatatgccatcaataagctgcggcaagaagggaacgaggag
gggatgtatgtgctgaggtggagctgcaccgactttgacaacatcctcatgactgtcacc
tgctttgaaaagtctgagcaggtgctgggtactcataagcaattcaagaattttcagatc
gaggtacagaagggccgctatagcctgcatggctcagatcgcaacttccccaccctggaa
ggcctcatgagccacctcaagaagcagatcctgcgcacagacaacatcagctttgtgctg
aagcgctgctgccagcccaagcctcgagaaatctccaatctgttggtggccaccaagaag
gcccaggagtggcagcctgtctaccccatgagccagctgagctttgaccggatcctcaag
aaagatattgttcaaggtgatcaccttggtagaggcacgagaacacacatctactctggg
accttggtggattacaaggacgatgaaggggctgctgaagagaagagaataaaagtgatc
ctcaaagtcttagaccccagccacagggacatttctctggccttctttgaagcagccagc
atgatgagacaggtctcccacaaacacattgtgtacctctatggcgtctgtgtccgagat
gtggaaaatatcatggtggaagagtatgtggaggggggacccctggatctctttatgcat
cggaaaagtgatgtcctcactacaccatggaaattcaaagttgccaaacagctggccagt
gccctgagttacttggaagataaagacctggtccatggaaatgtgtgtaccaaaaatctc
ctcctggcccgtgagggcattgacagtgaaattggcccattcatcaagcttagtgaccct
ggaatccctgtcactgtactgtcaaggcaagagtgcatagaacgaatcccatggattgct
ccagagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggt
accacactctgggaaatctgctataatggcgagatccccctgaaagataagactctgatt
gagaaagagagattctatgaaagccggtgcaggccagtgacaccatcatgcaaggagctg
gctgaccttatgacccgctgcatgaactatgaccccaatcagagacccttcttccgagcc
attatgagggacattaacaagctcgaagagcaaaatccagacattgtttcagaaaaaaaa
ccagcaactgaggtggatcccacacattttgaaaagcgcttcctgaagaggatccgtgac
ttgggagagggccactttgggaaggttgagctctgcaggtatgacccagagggggacaac
acaggggagcaggtagctgtcaaatccctgaagcctgagagtggaggtaaccacattgct
gatctgaagaaggaaatagaaatcttaaggaatctctatcatgagaacattgtgaagtac
aaaggaatctgcactgaagatggaggaaatggtatcaagctcatcatggagtttctgcct
tctggaagccttaaggaatatcttccaaagaataagaacaaaattaaccttaaacagcag
ctaaaatatgctgttcagatttgtaagggaatggactatttgggttctcggcaatatgtt
caccgggacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattgga
gactttggtttaaccaaagcaattgaaactgataaggagtactacaccgtcaaggatgac
cgggacagccctgtgttttggtacgctccagaatgtttaattcagtgtaaattttatatt
gcctctgatgtctggtcttttggagtgactctgcatgagctgcttacttactgtgattca
gagtctagtccaatggctttgttcctgaaaatgataggcccaactcaaggccagatgacg
gtgacaagacttgtgaatacactgaaagaaggaaaacgtttaccatgcccgcctaactgt
cctgataaggtttatcaacttatgagaaaatgctgggaattacaaccatccaatcggaca
acctttcagagccttattgaaggatttgaagcacttttaaaatatgaagcatga
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integrated database retrieval system
