Marmota marmota marmota (Alpine marmot): 107143378 Help Entry 107143378         CDS       T09644                                  Symbol Syne2 Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:mmma00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     107143378 (Syne2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mmma03036]     107143378 (Syne2) Chromosome and associated proteins [BR:mmma03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     107143378 (Syne2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin_SYNE1 CH KASH Spectrin SYNE1 CAMSAP_CH Motif Other DBs NCBI-GeneID:  107143378 NCBI-ProteinID:  XP_048654426 LinkDB All DBs Position Unknown AA seq 6925 aa AA seqDB search MASSPDLPHRNQQAALGIDHLQVSLQAKQEDTQKKTFTCWINSQLAKHTSPSVISDLFAD IRKGHVLLDLLEVLSGQQLPRDRGYNTHQCRLNIEHALKFLENQSVKLINVHVADIIEGN PSIILGLIWTIILHFHIEDLAQSDSCNYNQASPDDMSVADSSPTSSPPAKRCLKVQERWQ LSAKKVLLLWAQDKCARYESVSVTDFKSSWRNGMAFLAVIHALRPDLVDMKSMKHRSNKD NLKEAFGIAERELKIPKLLDPEDVDVVNPDEKSIMTYVAQFLQYSKDASRTGDMTQSKVK DAMAWLALQEKKLQEALKESEGKTYFKKYHSLTSYMELFNEEKVRFLEVLSPKRDQQELN EDELQLREAWDGINQKINAWKTNLNDALPWPLCEIEAWLQEVMELMEEELPTSQNYSEAM AQTEEKMTLFKSLMDRSDYHSSILMAFENKDEEHLPLVPLNTLEEMKRRVNNTLGNNFTL LLEFHYFKCSVLGLLDEVKPKLDFWNIKFGKKESVELLLEDWHNFIEEKEFIAQLDTAFQ KCEEIYKNLAGERENINEQYMVMESNISMYRKNIYNVKSTLEKVLACWATYEENLRLLKA GFEETKKQVKEVPFETLAQWNVEHTTLNEVGSFLIEVSNDEVGSSVSKELRRLNKRWRKF ITKTPLEMKLPLSKKQDQPTLDNSRNIVLPKEEEKSTVDFSKNMSVGLPENYNRNIKAVE EHEKDHEESTEHLKVAEEVEKLIGQVEVWEAETKSILDLPKHQDIMDSTIEKSLQHLIAR GSMYEELLARTEDTLRMDVQNISSQESLQHVLTTGLQAKIQEANEKVQITVVKLIAMLKN STDISQELDAKQKVKESQMELESYIVRAEQLLGQRQSPRGLISKYKEALKIFNTNSLAKY LKAVEELKLNVPEDVKLSLEEKRREACAKWESLHQEISLYIQQLKIDIEKGKLNDNISKL EKQINKEKKLIRRGKTKGLIKEHEACFSKEVIVCQLHHHVDVLKALCEELTSQEHQQEVQ RVLKDYEQKIERLLKCASEIHVTLLAPVGGTSKDELELPKSSQALGETVTTAENGGKGFH SEVPFAKPDNQLSTEKVVEPVENFSLTSELKLQQQESIMEQLEEDHSASKNRLQKRYDTH KEILELHLQNNKFRITSDFSSENEMSSANLQNKLTDLQVLKNETNACWKEFESTSLELES LMNDTEKPLIVKERDRLKEKENELQMSLNTRVESLEMALQVLLPVEKESLFLCGSDLFPC QVAIQEFHLVDTDGIYQNLRNIQDSIAKQIKVCTSLEEPGNIVLKDLYPLDLHATQNIIL KCKTQLEEMNHKLRMSEEVLKALGEFIDSVRTVKLSVDLVTDLSASDAPVAPENTLTVKN IKREIRLMRDKARHLDERLKMLDISFEDADLGEDTSCKKLLDALTMKLFETRICDTQEAF AEEINLVETCTSKNAELFKNIQDMQNQIGKIGLKDPTVPAVKHRKKLLLKLEKDIDGYEE EKIHLEEMVDSLPQFKDGREKPLIQQCQTTLLLWENTKTSIAECLDQCGRVLELLKQYQN FKGILTTLIQKEENVISLQSSYMGKENLKKRIAEIEIVKEEFNEHLESVDKINQICKNLQ FYLNKMKTFEEPPFAKEANVIVDRWLDINEKTEDYYENLGRALALWDKLFNLKSVVDEWT ENVLRERNSQLTEEDRERLKEELQVHEQQTSEFSRRVTEIQFLLQSNEKPLELQVMERSI LNKMEHVKKYISGESNCFELGSSTAELREDLDQAKTQIGMTESLLKALSPSDSLEIFTKL EEIQQEILQQKHNMIVLEHQIGCLTPELSELKRQYESVSDLFNTKKGVLQDHFSSLLNDQ CKNFNDWFSKIKVRLEECFDSSETKKSVEQKLQILSDFLTLEGRSSKIQQVETVLQHVKK HLPKAHVKELNSWLVSQEVELEKMVSICEAQAKELNNYLEQLLRLQDDCRSLSKWLTNQE EEWKEMEESGEKTELFCQALAEKREHFESLVQLNDSLKDHGFTEEDEIINESTCLIERYQ TLLRQLHEIEEEFKLPPAEDQSFNDLAHDVIHWIQEIKESLMALNSSEGKMPLEERIQKI KEIILLKPEGDAKIQTITRQAESCEAPLVQETLADITNQWDSTLHLASTYLSHQEKLLLE GEKYLQSKEDLRLMLIELRKKQEAGFALQHALPEKKAQLKIYKKFLQKAQDLTSLLKELK SQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQDSVQKLEDHVEEHHSYEVCIKELNT TLDNISMELVSFSDLPVDQTAIEDKLQKLQELESRLSLQDGTLKKILALAKSIKQNTSSV GQIIIKDDIKSLTCKQKDLENRIESAKQETENYLNSLLKSKCSIEKNEKFPLPGRQRQAT SEVVESTWLLVGVEELEEDWEVNKNSDVEMVLSKQFPLHVQESMNNAEDEHKVNELQNQP LELDVLLRNEQLEEIEELYNRLEARKTAIEPLEQSECFNKTEASALALHNKRYSAQHLDN LLQALTALKKNKESQYYLLKHFQEHVTAVESLMKALLTEKESLKVGPMDSEIYLNKIKKF LRSIEKEKVSLSKLKAEWESLSPHVTDMDKKLMENQIQQLEHGWEQMEHMVQKKHSQQVM EYGEFTSLVNKFQDMETSLQEQQQCLLLRLNSLEEQEGSHSIIASAIELQAIKHGFSILK TQAELQMKRFWGEKEKKILEDAINNLKKQLETLDPLNLEVENRIKKCDIKNKMKETIQWV KNLQGTLTPYICLFPDDILSQIRKCKMAHDGILDKQQVMESLVKEVKDIIPNLTADEGDD LNSLLEDLQSQYQMLVLKSTQRSQQLEFKLEERSQFFAGIGKAQLTLQRKEALIIPKMEA ASTETELAHVHFTLKASQEELREIGSVISTHLQELANTCKDLNVFERLFLDDHLKHLKTR ASRTRRFIQSKCNEVEHKINSYRELHEETSGLQREVDRIQHKELLLNQDINQDVKEFNNL KDRLTGVRCEILQLLELKELFDYTGINWDCSQLNQLKTQVFEKEKKLEEKIRQLDTFVAE HGKYQALLSKVRDMDLQIKKRAELVQKAPDTSPESNLLNAIILNQKIEKAKCLYNEVLKK LSENKALDDSFKEKEIVQLTLNVEENDKLQKVVKNIVLEFQPKEIDEKNFQDLLENSLHV LNQIKSHVQQPLLINLGIEHIENEKDNCEAFLELVQEEMCSIKAVTVTEKQREENSPETG DMETKLQDVEALQTQLSRSIDLRMDALNNAYENITLYNEAVARAMEIITSLEAIIASPRV NLHNPQKSLERFRWKQKELESTIADIQDLIENLGTISAPEAKQEFQCTLQELISKNSAMK EAATVKAALVERCLENYKRYRSIKEYICTHLRKMETVLRQSMSPLPVSYKEALERLEQSK ALVSNLKSTRKELMKLRQVLRHLRRRCTEKDGVCVLRGLLVLWEKWLSLLQTAKVWEMWS EELKQEWKFVSEEMERETIILDNLQEELPEISKTKEAATTEELSELLDAFYQYEESVEMQ QLLLTLLLQRIKSIWNVPEGRGAVEAVPALQEIQSMRERCDRLLQKAQKNKESLQTELQG RHSFTKEIIALKNVFQQASTSFQNMASEGHPERAKQLEELQSILKKGKLTFKSIMEKLRI QYCEMYTIVPAEMESRVEECRKALEDIDEKISDEVLKSSPSFAMNRKIEEINSGLQLVEN MLQQKSENIEKAQEIQKKLWDKLDLWHSKLNELDSEVQDIVEQNPGQAQEWMDKLMIPFQ KYQQVSQRAETRTSQLNKATIKMEEYSDLLKNTQAWIENTSRLLANPARYDSSRTLSHHA STLQRALEDSEQKHNLLHSVFADLEDLSDIFETDDLVQSVQDLSSQVVDLQQQIMESLPH IQRMADDVVAIESEVKSMEKKVSKIRTILLSKEIFDFSPEEHLKHGEVILENIRPMKKTI AEIVSYQVELRLPQAGTKPLPVFQRTNQLLQAVKLLENVTQEQNELLKVVIRQTNECNEE IESLKQILNNYSTEFSLEQISPDQAVDFPEVQEDIKSMEQQILHLNQKKEDLLVDLKAAV LNLHQHLKQEQQEGDVLSARALEDGGTAELDVSEWKLDRPGSMSFLPAVKEEAEEGSLKS ENEYKKAEPSSRSLPLLWKHDLGLEEDGESSSSATIIPEADGKISTCDSSMVQILAPDSL NTEQSLAFSPKLNQTEEGPTPPIKAAALDFSDKPGDFETSVKRTRARPVEVLHACKTQVA ELELWLQQASVAFEPETLNADMQQVVEQELVGCQAMLTEIEHKVASLLDTCKDQGLGDSG ATQQEAEALSLKLRTVKCNLEKVQMMLQEKYSEDQYPTILRKPSELQQVLQPVNLPELVP IVTERPQFSRQRDVPVQQVLELKPMEQKDLLKFIEFNAKKTWLQYCQQDKDTTQGSSVSN KASGPENEAPDLIFSPQGQNGDKWQYLHHELSSKIKLPPPQLVGPQVTTNMSILPSVSVY NFRYPTTEELKMYTTQLEDLRQEANNLQTQENMTEETYNDLDKKLFELFLSLNQCLGSVE EMLQTPGLFREDVSAQQEHYEKLALELKKLYLALCDKKNDLLKAMAWSGRNTTLLLECFG SLQVCLEHTQASAASRSKSLKAGLDYKHSYQNEIKRLYDQLIKNKTALQQSLNEMRGQSI GEQLQKADLYTAELQNSESRVAKLRDEGERLRLPCVLLQEVYKLEDVLDSMWGILRARYS GFSSPFITESQQHALLQGTVELVNIGKEMLAHGHLKQAKSKVALQTQIQNHKVFFKKLVA NMLLIQTYYDKMFPSVLPKRERFWAEQVTEVKSLEGKAQQFGMKLQSLLQKWEEFDENFG SLEKDLEILISTLPSVSLVEETEERLVERISFYQQIKRNIDGKHARLYQTLNEGKQLVAS VSCPELEGQIAKLEEQWLSLNKKIDLELHRLQTLLKHLLSYNRDSDELTKWLESSQQTLN HWKEQSLNASQDLDTIRSNINKFFEFSKEVDGKSSLKTAVLSTGNQLLHLKETDTATLRA SLAQFEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNSVEYQAAGGDSVHFP SSESQVKNLLQKLKEFRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMN RQWHRVHGTLNKKIQHLEQFLESITENENKMQILKNWLEAQEEKLKTLQKPKSVISIEKV LLDCQDIENQLAIKSKVLDELRQSYLTLESGAIPLLEEAASGINKLLQKRDSVIRQVSEL KSFMQSVLQEWKLYDKLYDEVNMLAIQFGYCMEHSKPVVLSLEALRCQVQNLQSLQDEAE ISEGSWEKLREVIHRLKDSCPSVAEIIEEKCQDTHARWTQVNQDLADQLQEAQTLLQLWK AYRSAHVEATARLEQQEAKFQQLANINMSGNNLAEILPVALQDIKELKQDVQKTKEVFLQ NSILLDRFPQPAESNASGLFSGQLYSLRRAIYLEEMLLVKANEFEFVLSQFKDFEDRLES LKGLIIHEEENLDKLYQQDKEENPGLFLNHVLALIAQSPDIERLNEDSLMLPLSDMPLKT LQNMNRQWIRATATALDRCSELQESGLNENFLHCCEKWVQLLEKIEETLKANIANSLPAL LEQQKAYEMLEAEVSINQTIADSYVTQSLQLLDTTEIEKRPEFVLEFSNLTDHWQSAAQG IRQRKSDIDQLVRQWLYFTSSMEDLFRFLTNTSHMLSAVKDQDCYSLYQIRSLIHELKNK EIHFQRWQTTYALTLEAGEKLLNTPNLEAKESMNKRIRQLQNNWKDTELHLAQMIKHLQS IIETWDRCEKKIKELKSRLQVLKAQSKDPLPELHEDLHRERELTKELEKSLTNWTQNLQE LHTMKGDLTRHILSEDVMVLKEQIEHLHRQWEDLCLRVATRKQEIEDRLNSWIVFNEKNK ELCAWLVQMENKVLQTADISIEEMIEKLQKDCMEEINLFNENKLQLKQMGDQLIKASSKT RAAEIDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSK PVVYDVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQ QTTRSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEV LYTNAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASKLKQMVHEGNQRWD NLQKRVTAILRRLRHFTNQREDFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLN GFQQEITLNTNKIDQLIVFGEQLIQKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRL TSHAPGLEDEKEASETETDMEDPREIQTDSWHKRGESEEPSSPQSLCHLVPPALSHERSG CETPVSVDSIPLEWDHTGDVGGSSSHEEDEEGPYYSALSDVEIPENPEAYLKMTTKTLKA SSGKSISDGHSWHVPDSPSHPKHHYKQMEGDRNVPPIPSGSSTPYKSAYGKLLLQPGTDG GKESPRVLNGSPQQEDEHLATLRGQPSGAFDRWELIQAQELHSKLRMKQNMQQLNSNISA ITAWLGKTEAELETLKMAKPPSNIQEMEPRVKRLQEILKAFDNYKALMVSVNVSGKESLP TESTEATELQSRLRQLGLRWEAVQGAVDSWRGDLRQSLMQCQDFHELSQNLLLWLASAEN RRQKAHVTTPKANRQVLQECQKELMQLKKELVERQPQVNSLQELSTSLLVKGHGEDYIEA EEKVHVIQKKLKQLREQVSQDLMSLRGSQNSDPSLLNFDEVDSGDQPSAAAMAAPQAKQV RAERTTEDENETDSRMSGPGSSQPRRSFLSRVIRAALPLQLLLLLLLLLACLLPSSEEDY SCTQANNFARSFYPMLRYTNGPPPT NT seq 20778 nt NT seq  +upstreamnt  +downstreamnt atggcatctagtcctgaccttccccacagaaatcaacaggctgccttgggcattgaccat ctccaggtgtcactgcaagccaaacaggaagacactcagaagaaaaccttcacctgctgg ataaattcacagttggccaagcacacctctccctcagttatatcagacttattcgcagac attagaaaggggcatgtcctcttggatctgctagaagtactctcaggacagcagttgcct cgtgatagaggatataatacacaccagtgtagactcaatatagaacatgctctgaagttc ctagaaaaccaatcagtcaagctaataaatgtccacgttgctgatattatagaaggaaac ccatccattattcttggactaatttggacaattatactgcacttccatattgaggatctt gcccagtctgattcttgcaattacaatcaagcttccccggatgatatgagtgtggctgat tcatctcctacctcaagtcctccagcaaagagatgcctcaaagtccaagagcgatggcag ttgtctgcaaagaaagttcttctcttgtgggctcaagacaaatgtgccagatatgagtct gtcagtgtgacagattttaagtcaagctggagaaatgggatggcttttctggctgtcatt catgccttgcgaccagacctagttgacatgaagagtatgaagcatcgatccaacaaggac aatctgaaagaggcctttggaattgcagaacgagaattaaaaatccccaaattgctggat ccagaagacgtggatgttgttaaccccgatgaaaagtcaatcatgacctatgtggcacag tttctgcaatattccaaggatgcttctcggactggagatatgactcagagcaaggtaaaa gacgctatggcctggctagctctgcaagagaaaaagctacaggaggcactgaaggagtca gaaggcaagacctactttaaaaagtaccatagcctgacgtcctatatggagttattcaat gaagaaaaagtacgctttctggaagtactgtcaccaaaaagggatcagcaggagctgaat gaagatgaattacagttgagagaagcctgggatggcatcaaccaaaagattaacgcatgg aaaacaaacctgaacgatgccttgccctggcccctctgtgaaattgaagcgtggcttcag gaggtcatggaactcatggaggaggagttaccgacctcgcagaattactccgaagccatg gctcagacagaagagaaaatgactttattcaagagtctgatggacagatctgactaccat tcgagtattctcatggcttttgaaaataaagacgaagagcatttgccattggtgcccctt aacaccctggaggagatgaagagacgagtgaacaacactttagggaacaatttcactcta cttctagaatttcactactttaaatgctcagttcttggcttgctagatgaagtgaaacca aaattggatttttggaacataaaatttggaaagaaagaatctgtggaattattgctggaa gactggcataattttattgaagaaaaagagttcatagctcaacttgatactgcttttcaa aaatgtgaagaaatttataaaaatttagctggagaacgtgaaaatattaatgaacaatat atggtgatggaaagtaatatttctatgtacagaaaaaatatatataatgtgaagtctact ctagaaaaagttctggcctgttgggctacttatgaggagaaccttcgcttactgaaggct ggttttgaggagacaaagaaacaagttaaagaggttccctttgaaacacttgcccagtgg aatgtagaacacaccactttaaacgaagtgggaagtttcttaattgaagtcagcaatgat gaagttggatcatctgtttctaaagaactgagaaggctgaataaaagatggagaaagttt attacaaaaactccacttgaaatgaaattgccactttcaaaaaaacaggatcagcccact cttgacaattctagaaatattgtattacctaaagaagaagaaaaatcaactgttgatttt tcaaagaatatgtcagtaggacttcctgaaaattataatcggaatataaaggctgtggaa gaacatgaaaaagaccatgaggaatccacagaacacctaaaagtggctgaagaggttgaa aaactcattggacaagtggaggtgtgggaggcagaaaccaaatccattttggatcttccg aaacatcaagatattatggatagtaccatagaaaaatctttgcagcatcttattgccaga ggctcaatgtatgaagagcttctggccagaactgaagatactttacgaatggatgttcag aatatttcaagccaggagtccctccagcacgttctcacaactggacttcaggcaaagatt caagaagcgaatgagaaagtccagatcactgtggtaaaattaattgcaatgttgaagaat tcaacggatatttcacaagaattggatgccaagcagaaggtaaaagagtcccagatggaa ttggaatcttacattgtgagagctgaacagttacttgggcaaagacagagcccccgtgga ctcatttcaaaatataaggaagcactgaaaatttttaatactaatagtctggctaagtat ttgaaagcagttgaagaactgaaacttaacgttcctgaggatgtaaagctgtctttggaa gagaagaggagggaggcctgtgccaaatgggagtctcttcatcaagaaatttctttgtat attcagcaactaaaaatagatatcgaaaaaggaaaacttaacgacaacatttccaagctt gaaaagcaaataaataaagaaaagaaacttattcgtagaggaaagactaagggtctcatc aaagaacatgaggcctgcttttctaaggaagtcattgtgtgtcagctccatcaccatgtg gatgtcctgaaggcgctgtgtgaagagctgacttcgcaggagcatcagcaagaagtgcag agagtgctcaaagattatgagcaaaagatagaaagacttctgaaatgtgcttctgagatc catgtgactctgctggcccctgtggggggcacatcaaaagacgagttagaacttccgaag agtagccaggctttgggggaaactgtgaccacagctgagaatggcggaaagggtttccac agtgaggtgccatttgctaaaccagataatcagctgtcgactgaaaaggtagtggaacct gttgagaattttagcctgacatcggagttaaaactccaacaacaagaaagcattatggag cagctggaagaagatcacagtgcatctaaaaatagattacaaaagaggtatgatacacac aaagagattcttgaactacatctgcaaaacaacaaattcaggattacttctgatttctct agtgaaaacgaaatgagtagtgctaatctgcagaataaactaacagatttacaggtctta aaaaatgaaactaatgcttgctggaaagagtttgaaagcacttcattggagttagaaagt ctcatgaatgacacggaaaagcctcttatagttaaggagagagacaggttaaaggaaaaa gaaaatgagcttcaaatgtctcttaataccagagtggagtctttggagatggcactgcag gtcttattaccagtggagaaagagtcactcttcctgtgtggctcagacctatttccctgt caagtggccatccaggaatttcatctcgtggacactgatggcatttaccaaaacttgagg aacatccaagattccatagccaaacagattaaagtatgtaccagtttagaagagcctggc aacattgtattaaaggatttatacccacttgatctacatgcaacccagaatattatactg aaatgcaaaacacagcttgaagaaatgaaccacaagctgcggatgagtgaagaggtcctg aaagctctgggagagtttatagattctgtaagaacagttaagctctctgttgatcttgtt accgacctttcagcttcagatgcaccggtagccccagaaaatactttgacagtgaaaaat atcaagagagaaattcgtctgatgagagacaaggctaggcatttggatgaacgtttgaag atgcttgatataagctttgaagatgcagacctaggtgaagacacttcctgtaaaaaactt cttgatgccctaacaatgaagttattcgagacacgtatctgtgacacacaggaagcattt gctgaggaaatcaatttagtagagacttgtacttccaaaaatgcggaactctttaaaaat attcaagacatgcaaaatcagatcggtaaaattggtcttaaggatcctactgttccagct gtaaaacatcggaaaaaattattacttaaactggagaaggatatagatgggtatgaagaa gagaagatacacttggaagaaatggttgattctctcccccaattcaaagatggcagagaa aaacctctgattcaacagtgccaaactaccctgctcttgtgggaaaatacaaaaacatcc attgctgaatgtcttgatcaatgtggaagagttttggagctcttaaaacaatatcagaat tttaaaggtatcttgacaactttgattcagaaagaagagaatgtcatctccctgcagtct tcctacatgggaaaggagaacctgaagaaaaggatcgcagagattgaaattgtcaaagaa gaatttaatgaacatttagaatcagttgacaagataaaccagatctgtaaaaatctacaa ttttatctaaataaaatgaaaacctttgaagagcccccttttgcaaaagaggctaatgtt attgtggatcgatggcttgatataaatgagaagacagaagactactatgaaaatcttggt cgagctctggctttatgggacaaactttttaatttgaaaagtgtcgttgatgagtggact gaaaatgtccttcgagaaaggaattcacagctgactgaagaggacagagaaaggctgaag gaagagttacaagtccatgaacaacaaacttcagaattttctagaagagtgactgaaata cagtttctgctccaaagtaatgaaaaaccacttgaattgcaggtcatggaacgctctatt ttgaacaagatggaacatgtgaaaaagtatatatcaggagagtccaattgcttcgagctt ggtagcagcacagctgagctcagggaggatctcgaccaagccaagacccagatcgggatg acggagtccctcttgaaagccctgtctccttccgacagcttggaaattttcactaaactc gaggagatccaacaagaaattctacagcagaagcacaatatgatagtacttgagcatcaa ataggttgtctcacccctgaactctctgaattgaagaggcaatatgaaagtgtcagcgat ttatttaataccaaaaaaggtgttttgcaagatcacttttcttcattattgaatgatcaa tgcaagaatttcaatgactggttcagcaagattaaagtgaggcttgaagagtgcttcgac tcatcagaaacaaaaaagagtgtggaacaaaagctgcaaatactttctgatttcttgact cttgaaggaagaagcagtaaaatacagcaggtagaaactgtattgcagcatgtgaagaag cacctacctaaagcccatgttaaagagcttaacagttggcttgtgagtcaagaagttgaa ttagaaaaaatggtgtccatatgtgaggcccaggcaaaggaactcaataactacctggag cagctactgagactgcaggatgattgcagaagcctgagtaagtggttgactaatcaagaa gaggaatggaaagaaatggaagaatcaggagagaaaactgagctattttgtcaagcatta gctgaaaagagggaacattttgaatctctggtccagttgaatgactctttgaaggaccat gggtttactgaggaagatgaaataataaacgaatcaacatgtttgattgaaagataccag acattattgagacaattacatgaaattgaagaagaatttaagttgccacctgctgaggac cagagctttaatgatcttgcacatgatgtgattcattggatacaagagattaaagagtct cttatggctttgaactcatctgaaggcaaaatgccactcgaggaaagaatccaaaaaata aaggaaatcattttactaaagcctgaaggggacgccaaaatacagaccattacgagacaa gccgagagctgtgaggccccgttggtgcaggagacccttgctgatatcaccaaccagtgg gacagcacgctgcatctggccagcacatacctaagccatcaagaaaagcttctgctagaa ggggaaaagtatttgcaaagtaaggaggacttgagattaatgctcatagaactaaggaag aagcaagaagcaggctttgcccttcaacatgctctgccagagaagaaagcccagttaaaa atttataagaaattcctccagaaagcacaagatttgacatccttgctaaaggagttaaaa tctcaaggaaattacctcttggagtgcactaaaaatcccagcttcagtgaggagccttgg ctggaaataaaacatctacatgagagtcttcttcaacaactgcaggattctgtgcaaaaa ttagaggatcatgttgaagaacaccattcatacgaggtttgcatcaaagagctgaatacc acattggacaatatctccatggaattagttagtttttctgatttgcccgtggatcaaaca gcaattgaggacaaattgcagaaactgcaggaactagaaagtagactcagtttacaagat ggcacactgaagaagattttagcattagcaaaatccatcaagcaaaatacatcttcagtg ggacagattattattaaagatgatataaaatcacttacgtgtaaacaaaaagatttggaa aacagaattgaatctgctaaacaggagactgaaaattatctcaacagccttctcaaatca aaatgctcaatagaaaagaatgagaagtttcctctgccaggcagacagaggcaggccact tctgaggtggtggagtccacttggctcttggtgggagtggaagagctggaggaagactgg gaagtaaacaagaattcagacgtggaaatggttttgtcaaaacaatttcctctccatgtt caagaaagcatgaacaacgccgaagatgagcacaaagtcaacgagctgcaaaatcagccc ttggaattggatgttctgctgagaaatgaacaattagaagagatagaggaattatataac 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tcattggtgaaggaggtcaaagatatcattccaaaccttacagcagatgagggggatgat ttaaatagcctcctggaggacttacagagtcaatatcaaatgctagttttaaaatcaact cagagatcacagcagttggaatttaaattggaagaaagaagccaattctttgcagggatt gggaaggctcaactcactcttcaaagaaaggaagcactgatcattcccaagatggaagca gcctccacagaaactgagctagcacatgtccacttcactttgaaggcatcccaggaggag cttcgagaaattgggagtgtgatctcaacacatcttcaggaactagcaaacacctgtaag gatctaaatgtctttgaaagattatttcttgatgaccatttgaaacatctgaagaccaga gccagcagaacacgaagattcattcagagtaagtgcaatgaagtagaacataagataaat tcttatagagaactccatgaagaaacatctggtcttcagagggaggttgatcgtatacag cataaggaactactacttaaccaagacataaatcaagatgtgaaagagttcaataatctt aaagacagacttactggtgttcgatgtgagatcttacaactattagaacttaaagaactg tttgactacacagggataaactgggactgttcacaacttaaccaattgaaaacccaagta tttgaaaaagaaaagaaacttgaagaaaaaatcagacagttggatacgtttgtggcagaa catggcaaatatcaagcattactgagtaaagtaagggatatggatttgcaaattaagaaa agggctgaattagtacagaaagctcctgatacctcaccagagagcaatttgctcaatgca ataattttgaatcagaagattgagaaagcgaagtgcttatataatgaggtactaaagaaa 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gagttaaaaccaatggaacagaaagatttactcaagtttatagaatttaatgctaagaaa acatggctgcagtattgccaacaggataaagatactactcagggatcatctgtgagcaac aaggcatctggccctgaaaatgaagctccagacttgatcttttcacctcagggtcaaaat ggtgataaatggcaatatcttcatcatgaactgtcctcaaaaataaagctacctcctcct cagctcgtggggcctcaggttaccaccaatatgagtattctacccagtgtgagtgtgtat aactttagataccctacaacggaagagctgaaaatgtacaccacccaactcgaagacctg cgtcaagaagcaaataatcttcagacacaggaaaacatgacagaagaaacatataacgat ttggataaaaaattatttgagctcttcctgagcctcaatcagtgcctcggcagtgtggag gagatgctgcagacaccggggctcttcagggaggatgtctctgcccagcaggagcactac gagaaactggctctcgagttgaagaaactttatttagctctgtgtgacaagaagaatgat cttttgaaagccatggcttggtctggcaggaacaccactttgctccttgaatgtttcggt agcctccaggtctgcctggagcacactcaggccagcgctgcctctagaagcaagtccctg aaagcgggcctggactacaagcacagttaccagaatgaaataaagcgactgtatgatcaa ctcattaagaataagacagctttacaacagtccttgaatgaaatgcgtggccagagtatt ggtgaacagcttcagaaagcagatttatatacagcagagctacagaattctgagagccga gtggccaaactaagagacgaaggggagaggcttcgcttaccctgtgttttactccaggag 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tccctagcacagtttgaacaaaagtggaccatgctcataactcagcttccagatattcaa gaaaagcttcaccagcttcagatggagaaattgccatctcgtaaagccatcacagaaatg attagctggatgaacagcgtggagtatcaggctgcaggtggagactcggtgcacttccct agttctgagtctcaagtgaagaatcttcttcagaagctcaaggagttcagaatggaaatg gactataaacagtggatcgttgactttgttaaccagtcattgcttcagttaagcacctgt gatgtagaaagcaagcgctatgaaaggacggagtttgcagagcacctgggggagatgaac cgccaatggcaccgagtgcatggaaccctgaataaaaagatacaacatttagaacaattt ttggaaagtatcactgagaatgaaaataaaatgcagattttgaaaaactggttggaagca caagaagagaagctgaaaactttacaaaaacccaaaagtgtgatctccatcgagaaggtg ctcctggactgtcaggatatagaaaatcaacttgcaattaaatccaaagtactggatgag ctgagacaaagctacctgactctggaaagtggggcaattccattgttagaagaggcagca tctggaatcaacaagttgcttcaaaagcgggacagtgtgattcgtcaggtcagtgagctc aaaagcttcatgcagtcggtgctacaggagtggaagttgtatgataaactctatgatgaa gtgaacatgctggcgatccaatttgggtactgcatggaacacagcaagcctgtggtgttg tcactggaggccttgaggtgccaggtgcagaaccttcagtctcttcaagatgaagctgag atcagcgaagggagttgggagaaactccgggaggttattcatagactcaaagattcctgc ccctcagttgctgaaataattgaagagaaatgccaagacactcatgcaaggtggacccag gtaaaccaagatcttgcagaccagttgcaggaggcccagactctgctccagctctggaaa gcttatcgcagtgctcatgtggaagccacggcaaggctggagcagcaggaagccaaattt caacagcttgcaaacatcaacatgtctggaaacaacctggcagagatcctgccagtggcc ctgcaggacataaaggagctgaagcaggatgtgcagaagacaaaagaagtctttctccaa aattccatcctcctggaccgattcccacaacctgcagagtccaacgcctcggggctcttt tctggtcaactgtattccctccggagagctatttatttggaagagatgctgcttgtgaaa gcaaatgaatttgagtttgttctctcacagtttaaggattttgaggaccggctggaatct ttaaaaggcctcattatacacgaggaagagaatttggataaactttaccaacaagataaa gaagaaaatcctggcttgttcctgaatcatgtgctagcattgatagcccagtctcctgac attgaacgtctgaatgaagacagcctcatgctcccactcagtgacatgcccctgaagaca ttacagaatatgaaccggcaatggattcgcgccactgccacagcgctggaccgctgcagc gagctgcaggaaagtgggttaaatgaaaattttcttcattgttgtgaaaagtgggtccaa cttttggaaaagatagaagagacgctcaaagcgaatattgccaacagcctccctgctctc ctggaacagcagaaagcttatgagatgttagaagctgaagtttctataaaccagacaatt gctgattcttatgtcacccagtccctacaactcctggacacaacagaaatagagaagaga ccagaatttgttttggaattctcaaatctgacggaccactggcagagtgctgcccaaggc attcggcagaggaagagtgacattgaccagctggtgaggcagtggctatacttcacctcc tccatggaggacttgttccgcttcctcaccaacactagccacatgctgtccgcagtaaag gatcaggattgctacagcctctaccaaatcagaagtctgatccatgagctaaagaataag gaaatccattttcagagatggcaaaccacctatgcactaaccttggaagctggggagaaa ttactgaacacacctaacctggaagcaaaagagtccatgaacaagagaatcagacagctt cagaataactggaaggacacggagctccatctagcacagatgattaagcatctccaaagc atcatagagacctgggaccggtgtgaaaagaaaatcaaggagctgaaaagcaggctgcaa gttttaaaagcacaaagtaaagatcctcttccagaacttcatgaggacctccacagagaa agagagctgactaaggaactagagaagtctctgactaactggactcagaacttgcaagaa cttcacaccatgaagggcgacttaacccggcacattctctcggaggacgtgatggttttg aaggagcagatagagcatttgcacagacaatgggaggacctctgcctcagagtggctaca cgcaaacaggagattgaagacagactcaattcatggatcgtgttcaatgaaaaaaataaa gagttgtgtgcgtggctggtccagatggaaaacaaggttctacagaccgcagatattagc attgaagaaatgattgaaaagttgcagaaggactgcatggaagaaataaacttgttcaat gaaaacaagttacagctaaagcagatgggtgaccagttgatcaaggccagcagcaagaca 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tttgacaactacaaggcattaatggtctctgtcaatgtgagcggcaaggaatctctccca actgagagcaccgaagccacagagctccagagtagactccgccagctgggcctgcgctgg gaagcggtccagggcgcagtggacagctggagaggggacctgcggcagtcgctcatgcag tgccaggatttccatgaattaagtcaaaacctgctcctgtggctggcaagtgctgagaac cggaggcagaaggctcatgtcaccactccaaaggcaaaccgccaggtcctccaggagtgc cagaaagaactaatgcaattgaaaaaggaactagtagaacgtcagcctcaagtcaactcc ctacaggagctctccaccagccttctcgttaaggggcatggagaagactacattgaagct gaagagaaggtccatgtcatccagaagaaactcaaacagttacgagaacaagtatcccaa gatttaatgtccttacggggaagccagaactcagacccatctctgctcaactttgatgag gtagactccggggaccagccttctgcagcagccatggcagctccccaagcaaagcaggtc agagcagagagaactacagaagatgagaatgagacagacagcaggatgtctggtcccggc agctcacagccacggcgctccttcctctccagggtgatcagggcagcgctgcccctccag ctgctcctgctgctgctgctgctcctggcctgtctgctgccctcctctgaagaggactac agctgcacccaggccaacaacttcgcccgctctttctaccccatgctgcggtacaccaat gggcctcccccaacctag

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