Marmota marmota marmota (Alpine marmot): 107144405
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Entry
107144405 CDS
T09644
Symbol
Cftr
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator isoform X1
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma02010
ABC transporters
mmma04024
cAMP signaling pathway
mmma04152
AMPK signaling pathway
mmma04530
Tight junction
mmma04971
Gastric acid secretion
mmma04972
Pancreatic secretion
mmma04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
107144405 (Cftr)
09132 Signal transduction
04024 cAMP signaling pathway
107144405 (Cftr)
04152 AMPK signaling pathway
107144405 (Cftr)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
107144405 (Cftr)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
107144405 (Cftr)
04972 Pancreatic secretion
107144405 (Cftr)
04976 Bile secretion
107144405 (Cftr)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
mmma02000
]
107144405 (Cftr)
Enzymes [BR:
mmma01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
107144405 (Cftr)
Transporters [BR:
mmma02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
107144405 (Cftr)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
AAA_21
SMC_N
AAA_29
T2SSE
AAA_16
AAA_22
RsgA_GTPase
MeaB
DUF87
DO-GTPase2
Intein_splicing
nSTAND3
NTPase_1
MMR_HSR1
Zeta_toxin
AAA_23
NB-ARC
Motif
Other DBs
NCBI-GeneID:
107144405
NCBI-ProteinID:
XP_048641986
LinkDB
All DBs
Position
Unknown
AA seq
1480 aa
AA seq
DB search
MQKSPLEKASVISKLFFSWTRPILRKGYRQRLELSDIYQIPSADSADNLSEKLEREWDRE
LASKKNPKLINALRRCFFWRFMFYGILLYLGEVTKAVQPLLLGRIIASYDPDNKAERSIA
IYLAIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQL
VSLLSNNLNKFDEGLALAHFVWIAPLQVTLLMGLLWDLLQASAFCGLAFLIVVALVQAGL
GRMMMKYRDQRAGKINERLVITSEMIENIQSVKAYCWEEAVEKMIENLRQTELKLTRKAA
YVRYVNSSAFFFSGFFVVFLSVLPYALIKGIILRKIFTTISFCIVLRMAVTRQFPWAVQT
WYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVEMENVTAFWEEGFGELLEKAKLNNNNRK
ISNGDNSLFFSNFSLLGAPVLKDINFKIEKGQLLAVTGSTGAGKTSLLMMILGELEPSEG
KIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIV
LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSKLMGYDSFDQFSVERRNS
ILTETLRRFSLEGDASVSWNETKKQSFKQTGEFGEKRKNSILNPINSMRKFSIVQKTPLQ
GNGMEDDSDEPLERRLSLIPDSEQGEAILPRCNVINTGPTFQGRRRQSVLNLMTHSVNQG
PSIHRRTTTTRKMSLAPQTNFTEMDIYSRRLSQESGLEISEEINEEDLKECFFDDVESIP
AVTTWNTYLRYITIHKSLIFVLIWCLVVFLAEVAASLVVLWLLKNNPPQDEGNSTKNANN
SYAVIVTSTSFYYVFYIYVGIADTLLALGLFRGLPLVHTLITVSKILHHKMLHSVLQAPM
STLNTLKAGGILNRFSKDIAILDDLLPLTIFDFIQLLLIVIGAVAVVSVLQPYIFLATVP
VIAAFIVLRAYFLRTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKA
LNLHTANWFLYLSTLRWFQMRIEIIFVIFFIAVTFISILTTGEGEGSVGIILTLAMNIMN
TLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEDSKSTKSIKPSKDDQLSKVMIIENQYVKK
DDIWPSGGQMTVKDLTAKYVDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL
LNTEGEIQIDGVSWDSISLQQWRKAFGVIPQKVFIFSGTFRKNLDPYELRSDEEIWKVAD
EVGLKSVIEQFPGKLDFVLLDGGYVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPIT
YQIIRRTLKQAFADCTVILCEHRIEAMLECQRFLVIEENKVRQYDSIQKLLSEKSLFRQA
ISSSDRMKLFPHRNSSKHKSRSQIASLKEETEEEVQETRL
NT seq
4443 nt
NT seq
+upstream
nt +downstream
nt
atgcagaagtcgcctctggaaaaggccagcgtcatctccaaactttttttcagctggact
agaccaattttgaggaaagggtacagacagcgcctggaattgtcagacatataccaaatt
ccttctgctgattctgctgacaatctatctgaaaagttggaaagagaatgggatagagaa
ctggcttcaaagaaaaatcccaaactcattaatgcccttcggcgatgttttttctggaga
tttatgttctatggaatcttattatatttaggggaagtcaccaaagcagtacagcctctc
ttactgggaagaatcatagcttcttatgatccagataacaaggcggaacgctccatcgcc
atttacctagccataggcttatgcttgctctttatcgtgaggacactgctccttcacccg
gccatttttggccttcatcacattggaatgcaaatgagaatagctatgtttagcctgatt
tataagaagactttaaaactgtcaagccgtgttctggataaaataagtattgggcagctt
gttagtctcctttccaacaacctgaacaaatttgatgaaggacttgcactggcacatttt
gtatggattgctcctttacaagtgactctcctgatggggctgctctgggacttgttacag
gcctctgctttctgtggccttgctttcctgatagttgtagcccttgtgcaagctgggtta
gggagaatgatgatgaagtacagagatcagagagctggaaagatcaatgaaagacttgtg
atcacctcagaaatgattgaaaatatccaatctgtgaaggcatactgctgggaagaagca
gtagaaaaaatgattgaaaacctaagacagacagaactgaaactgacccggaaggcagcc
tatgtgagatacgtcaatagctcagccttcttcttctcaggattctttgtggtgttttta
tctgtgcttccctatgcacttatcaaaggaatcatccttcgaaaaatattcacaaccatc
tcattctgcattgtgctgcgcatggcggtcacacggcaattcccttgggccgtacaaaca
tggtacgactctcttggagcaataaacaaaatacaggatttcttacaaaagcaagagtat
aagacattagaatataacttaacaactacagaagtagagatggagaatgtaaccgccttc
tgggaggagggatttggggaattacttgagaaagcaaaactaaataataacaatagaaaa
atttccaatggtgacaacagcctcttcttcagtaacttctccctccttggtgcccctgtg
ttgaaagatatcaacttcaagatagaaaaaggacaattattggcagttactggatctacc
ggagcaggcaagacttcacttctaatgatgattctgggagaactggagccttcagagggt
aaaattaagcacagtggaagaatttcattttgctctcagttttcctggatcatgcctggt
accatcaaagaaaatattatctttggtgtttcctatgatgagtatagatacaggagtgtt
atcaaagcatgccaactagaagaggacatctccaagttcgcagagaaagacaatatagtc
cttggagaaggtggaatcacactgagcggaggtcaacgtgcacggatttctttagcaaga
gcagtatacaaagatgctgatttgtacctattagactctccttttggatacctagatgtt
ttaactgaaaaggaaatatttgaaagctgtgtgtgtaaattgatggctaacaaaactagg
attttggtcacttctaaaatggaacatttaaagaaggctgacaaaatattaattttgcat
gaaggtagcagctatttttatgggacattttctgaactacaaaatctacggccggacttt
agttcaaagctcatgggatatgattcttttgaccagtttagtgtggaaagaagaaattca
atcctaacagagacattgcgccgtttctcattagaaggagatgcttctgtctcttggaat
gaaacaaaaaaacaatcttttaaacagactggagagtttggggaaaaaaggaagaactct
attctcaatccaatcaactcaatgagaaaattttcaattgtacaaaagaccccattacaa
ggaaatggcatggaagatgattctgatgagcccttagagagaaggctgtccctaattcca
gattctgagcagggggaggccatcctgcctcgctgcaatgtgatcaacactggccccaca
tttcagggccgaaggagacagtctgttctaaacctgatgacacactcagtgaaccagggg
ccaagcatccaccggaggacaacaactacacgaaaaatgtcattggcccctcagacaaac
ttcactgaaatggatatctattcaagacgtttgtctcaagagagtggcttagaaatcagt
gaagaaattaatgaagaagatttaaaggaatgcttttttgatgatgtagagagcatacct
gctgtgaccacgtggaacacatatcttcgatacatcactatccacaagagcttgattttt
gtgttaatttggtgcttagttgtttttctggctgaggtggctgcttctttggttgtgttg
tggctactgaaaaacaatcctcctcaagatgaagggaatagtactaaaaatgcaaataac
agctatgctgtgattgtcaccagcaccagcttctattatgttttttacatttacgtggga
atagctgacactttgcttgctctgggattattcagaggtttgccactggtgcatacacta
atcacagtgtcaaaaatcttacatcacaaaatgttacattctgttctacaagcacccatg
tcaaccctcaacacgttgaaagcaggtgggattcttaatagattctccaaagatatagca
attttggatgatcttctgcctcttaccatatttgacttcatccagttgttattaattgtg
attggagctgtggccgtggtctctgttttacaaccctacatcttcctagcaacagtgcca
gtgatagcggcttttattgtgttgagggcatatttcctccgcacctcacaacaactcaaa
caactggagtctgaaggcaggagtccaatcttcactcatcttgttacaagtctaaaagga
ctatggacgcttcgtgcctttggacggcagccttactttgaaactctgttccacaaagct
ctgaatttacatactgccaactggttcttgtatttatcaacgctgcgctggtttcaaatg
agaatagaaattatctttgtcatcttcttcattgctgttaccttcatttccattttaaca
acaggtgaaggagaaggatctgttggtattattctaactttagccatgaatattatgaac
acattgcagtgggctgtaaactctagcattgatgtggatagcttgatgcgatctgtgagc
cgtgtctttaagttcattgacatgccaacagaagacagtaaatccaccaagtccatcaaa
ccatccaaggatgaccagctctcaaaagttatgattattgagaatcaatatgtgaagaaa
gatgacatctggccctcagggggccaaatgaccgtcaaagacctcacagcgaaatatgta
gatggtgggaatgccatattagagaacatttccttctcaataagtcctggccagagggtg
ggtctcttgggaagaactggatcaggaaagagcacattgttatcagcttttttgagactg
ctgaatactgaaggagaaatccagattgatggtgtgtcttgggactcaatatctttgcaa
cagtggaggaaagcctttggagtgataccacagaaagtatttatcttttctggaacattt
agaaaaaacttggatccctatgaactgaggagtgatgaagaaatatggaaagttgcagat
gaggttggactcaagtctgtgatagagcagtttcctgggaagctcgactttgtccttctg
gatgggggttatgtgctaagccatggccacaagcagttgatgtgcttggccagatctgtt
ctcagtaaggcaaagatcctactgcttgatgaacccagcgctcacttggatcccataaca
taccaaataattcgaagaactctgaaacaagcattcgctgattgcacagtaatcctctgt
gaacacagaatagaagcaatgttggaatgtcaacgatttttggtcatagaagagaacaaa
gtgcggcagtatgattccatccagaagcttctgagtgagaagagcctctttcgacaggcc
atcagctcctccgacaggatgaagctcttcccccaccgcaactccagcaagcacaagtct
cgatcccaaattgcttctctgaaggaggagacagaagaagaggtccaagaaacaaggctc
tag
DBGET
integrated database retrieval system
