Marmota marmota marmota (Alpine marmot): 107146217 Help Entry 107146217         CDS       T09644                                  Symbol Gck Name (RefSeq) hexokinase-4 isoform X1   KO K12407   glucokinase [EC:2.7.1.2] Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma00010   Glycolysis / Gluconeogenesis mmma00052   Galactose metabolism mmma00500   Starch and sucrose metabolism mmma00520   Amino sugar and nucleotide sugar metabolism mmma00524   Neomycin, kanamycin and gentamicin biosynthesis mmma01100   Metabolic pathways mmma01200   Carbon metabolism mmma01250   Biosynthesis of nucleotide sugars mmma04910   Insulin signaling pathway mmma04911   Insulin secretion mmma04917   Prolactin signaling pathway mmma04922   Glucagon signaling pathway mmma04930   Type II diabetes mellitus mmma04950   Maturity onset diabetes of the young mmma05230   Central carbon metabolism in cancer Module mmma_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mmma_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:mmma00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     107146217 (Gck)    00052 Galactose metabolism     107146217 (Gck)    00500 Starch and sucrose metabolism     107146217 (Gck)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     107146217 (Gck)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     107146217 (Gck)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     107146217 (Gck)    04922 Glucagon signaling pathway     107146217 (Gck)    04917 Prolactin signaling pathway     107146217 (Gck)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     107146217 (Gck)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     107146217 (Gck)    04950 Maturity onset diabetes of the young     107146217 (Gck) Enzymes [BR:mmma01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      107146217 (Gck) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Sec2p NGO1945_C Motif Other DBs NCBI-GeneID:  107146217 NCBI-ProteinID:  XP_015345753 Ensembl:  ENSMMMG00000012459 UniProt:  A0A8C5ZEL6 LinkDB All DBs Position Unknown AA seq 495 aa AA seqDB search MPQLQLHPRPQQAEASPPSKNTSFLCPWRDAVESMRSQTQTALTLVEQILAEFQLQEEDL KKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVK VGEGEAGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTF SFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATM ISCYYEDRQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFL LEYDRMVDESSANPGQQLYEKLIGGKYMGELVRLVLLKLVDENLLFHGEASEQLRTRGAF ETRFVSQVESDSGDRKQIHNILSTLGLRPSATDCDIVRRACESVSTRAAHMCSAGLAGVI NRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAA LVSAVACKKACMLGQ NT seq 1488 nt NT seq  +upstreamnt  +downstreamnt atgccacagctacagcttcatcccaggcctcagcaagcagaagcatctccaccttccaaa aatacctccttcctgtgcccttggagagatgcagtggagtccatgaggagccagacccag acagccttgaccctggtggagcagatcctggcagagttccaactgcaggaggaagacctg aagaaggtgatgagacggatgcagaaggagatggaccgtggcctgaggctggagacccac gaagaggccagcgtgaagatgctgcccacctacgtgcgttccaccccagaaggctcagaa gttggagacttcctttccctggacctgggcggcaccaacttcagggtgatgctggtgaag gtgggggagggtgaggcagggcagtggagtgtgaagaccaaacatcagatgtactccatc cctgaggacgccatgacgggcactgcagagatgctctttgactatatctctgagtgcatc tccgacttcctggacaagcatcaaatgaagcacaagaaactacccctgggcttcactttc tccttccctgtgaggcacgaagacattgacaagggcatccttctcaactggactaagggc ttcaaggcctctggagcagaaggaaacaacattgtcgggcttctgcgagatgccatcaag aggagaggggactttgagatggatgtagtggcaatggtgaatgacactgtggccacaatg atctcctgctactatgaagaccgccagtgcgaggtcggcatgattgtgggtacaggctgc aatgcctgctacatggaggagatgcagaatgtggagctggtagaaggggatgagggccgc atgtgtgtcaacactgagtggggtgccttcggggactcaggtgaactggatgagttcctg ctggagtatgaccgcatggtggatgagagctctgcgaatcccggtcagcagctgtatgag aagctcattggtgggaagtacatgggtgagttggtgcgccttgtgcttctcaaactggtg gatgagaatctgctattccacggggaagcctcagagcagctacgcactcgcggcgctttc gagacccgattcgtatcgcaggtggagagcgactcaggtgaccgcaagcagatccataac atcctgagcacactggggctgaggccctccgccactgactgcgacattgtgcgccgcgcc tgcgagagcgtgtccacgcgagcagcgcacatgtgctcagcagggctggcgggtgtcatc aaccgcatgcgcgagagccgcagcgaggacgtgatgcgaatcaccgtgggtgtggatggc tctgtgtacaagttgcaccccagcttcaaggagcggttccacgccagtgtacgcaggctg actcccagctgtgagatcactttcatcgagagtgaagagggtagcggcaggggtgcggcc ttggtttccgcagtggcctgtaagaaggcctgcatgctgggccaatga

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