Marmota marmota marmota (Alpine marmot): 107148937
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Entry
107148937 CDS
T09644
Symbol
Nos3
Name
(RefSeq) nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00220
Arginine biosynthesis
mmma00330
Arginine and proline metabolism
mmma01100
Metabolic pathways
mmma04020
Calcium signaling pathway
mmma04022
cGMP-PKG signaling pathway
mmma04066
HIF-1 signaling pathway
mmma04071
Sphingolipid signaling pathway
mmma04151
PI3K-Akt signaling pathway
mmma04370
VEGF signaling pathway
mmma04371
Apelin signaling pathway
mmma04611
Platelet activation
mmma04915
Estrogen signaling pathway
mmma04921
Oxytocin signaling pathway
mmma04926
Relaxin signaling pathway
mmma04931
Insulin resistance
mmma04933
AGE-RAGE signaling pathway in diabetic complications
mmma05415
Diabetic cardiomyopathy
mmma05417
Lipid and atherosclerosis
mmma05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
107148937 (Nos3)
00330 Arginine and proline metabolism
107148937 (Nos3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
107148937 (Nos3)
04371 Apelin signaling pathway
107148937 (Nos3)
04066 HIF-1 signaling pathway
107148937 (Nos3)
04020 Calcium signaling pathway
107148937 (Nos3)
04071 Sphingolipid signaling pathway
107148937 (Nos3)
04022 cGMP-PKG signaling pathway
107148937 (Nos3)
04151 PI3K-Akt signaling pathway
107148937 (Nos3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
107148937 (Nos3)
09152 Endocrine system
04915 Estrogen signaling pathway
107148937 (Nos3)
04921 Oxytocin signaling pathway
107148937 (Nos3)
04926 Relaxin signaling pathway
107148937 (Nos3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
107148937 (Nos3)
05418 Fluid shear stress and atherosclerosis
107148937 (Nos3)
05415 Diabetic cardiomyopathy
107148937 (Nos3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
107148937 (Nos3)
04933 AGE-RAGE signaling pathway in diabetic complications
107148937 (Nos3)
Enzymes [BR:
mmma01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
107148937 (Nos3)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
107148937
NCBI-ProteinID:
XP_015349164
Ensembl:
ENSMMMG00000006221
UniProt:
A0A8C6EQC7
LinkDB
All DBs
Position
Unknown
AA seq
1202 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCSKQGPASPVSEPSRAPASPPSPPPAPDHSPPLTR
PPEGPKFPRVKNWEMGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKVQSRPSQSPPSTE
QLLGQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA
PRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNKGNIRSAITVFPQRSPGRGDF
RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNSRFDVLPLLLQAPDEPPE
LFTLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSE
IGMRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH
AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK
GSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRL
FRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP
RPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFC
AFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAAQ
DIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSRSTRATILV
RLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPPSEPVAVEQLEKGSPGGPP
PSWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYE
EWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLA
YRTQDGLGPLHYGVCSTWLSQLKAGDLVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPF
RGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSREP
DSPKTYVQDVLRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMELDE
AGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDTL
YP
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtgggccaggagcctgggccaccctgcggcctgggactgggg
ctgggcctcgggctgtgcagcaaacagggcccagcctctccagtatcagagcccagccga
gcaccagcatccccaccctcacccccaccggcaccagaccacagtcccccactaaccagg
cccccggagggacccaagttcccacgagtgaagaactgggagatgggcagcatcacctat
gacaccctcagtgcccaggcccagcaggatgggccctgcaccccaagacgctgcctgggc
tcccttgtatttccaaggaaagtacagagtcgaccctcccagagccctccatccactgag
cagctgctgggtcaggccagggacttcatcaaccagtactacagctccatcaagaggagt
ggctcccaggcccatgagcagcggcttcaggaggtggaggctgaggtggcagccacgggc
acctaccagctccgggagagtgagctggtgttcggggccaagcaagcctggcgcaatgct
ccccgctgtgtgggccggatccagtggggaaagctgcaggtgtttgatgcccgagattgt
aggtctgcacaggaaatgttcacctacatctgcaatcacatcaagtacgccaccaacaag
ggcaacatccgctcagccatcacagtgttcccccagcgctccccaggccgcggggacttc
cgaatctggaacagccagctagtgcgttatgctggctacaggcagcaggatggctctgtg
cggggggaccctgccaacgtggagatcaccgagctctgcatccagcatggctggacccca
ggaaacagtcgctttgatgtgctacccttgctgctccaggcccctgatgagcccccagaa
ctcttcactctgccccccgagctggtcctcgaggtgcccctagagcaccccacgctggag
tggttcgcagccctaggcctgcgctggtacgctcttcctgcggtgtccaacatgctactg
gagataggaggactggagtttcccgcggcccctttcagcggctggtacatgagctctgag
atcggcatgaggaacctctgtgaccctcaccgctataacattctggaggatgtggccgtc
tgcatggacctggatacccgcaccacgtcatccctctggaaagacaaggcagcagtggaa
attaacgtggctgtgctgcacagttaccagctggccaaagtgaccattgtggaccaccat
gcggccacagcctccttcatgaagcacctggagaacgagcagaaggccaggggcgggtgc
cctgccgactgggcctggatcgtgccccccatctcaggcagcctcactcctgtcttccac
caagagatggtcaactatttcttatcccctgccttccgctaccagccagatccctggaag
gggagtgcagccaagggcactggcatcaccagaaagaagaccttcaaggaggtggccaat
gcggtgaagatctctgcctcgctcatgggcacggtgatggcgaagcgtgtgaaggcaacc
atcctgtatggctccgagaccggccgggcccagagctatgcacagcagctggggaggctc
ttccggaaggcgtttgacccccgggtcctgtgcatggatgaatatgacgtggtgtccctg
gagcacgagaccctggtgttggtggtgaccagcacatttgggaatggagatcccccagag
aatggagagagtttcgcagcagccctgatggagatgtccggcccctacaacagctcccct
cggccagagcagcacaagagttacaaaatccgcttcaacagtgtctcctgctcagacccc
ctcgtgtcctcctggcggcggaagaggaaggagtctagcaacacagacagcgcaggggcc
ctgggcaccctcaggttctgtgtgttcgggctgggctccagggcatacccccacttctgt
gcctttgctcgggcggtggacacgaggctggaggagctgggtggggaacggctactgcag
ctgggccagggcgacgagttgtgtggccaggaggaggccttccgcggctgggcccaggct
gccttccaggcctcctgtgagaccttctgtgtgggggaggatgccaaggcagcggcccag
gatatattcagccccaagcgcagctggaagcgtcagcggtaccggctgagtgcccaggct
gagggcctgcagctgctgccaggcctgatccatgtgcacaggcggaaaatgttccaggcc
acagtcctctcagtggaaaacctgcaaagcagcagatccacccgggccaccatcctggtg
cgccttgacactggaggccaggaggggctgcagtaccagcctggggaccatataggtgtg
tgcccacccaaccggcctggcctcgtagaggcgctattgagccgcgtggaggacccgcca
ccacccagcgagcctgtggcagtggagcagctggagaagggcagccctggtggccctccc
ccgagctgggtgcgggacccccggctgcccccgtgcacgctgcgccaggctctcacctac
ttcctggacatcacttctccacccagccctcgcctccttcgattgctcagcactctagcc
gaagagtccagcgaacagcaggaactggaggccctcagccaggacccccggcgctatgaa
gagtggaagtggttccgctgtcccacactgctggaggtcttggagcagttcccatcagtg
gcactgcctgcgcccctgctcctcacccagctgcccctgctccagccccggtactactcc
gtcagctcagcacccagcacccacccaggagagatccacctcaccgtagctgtgttggca
tacaggacccaggatgggctgggccccttacattatggagtctgctccacatggctgagc
caactcaaggctggagacctcgtgccttgcttcatcagaggggctccctccttccggcta
ccacctgatcccagtctgccctgcatcctggtgggcccaggcactggcattgcccccttc
aggggattctggcaggagcggcttcacgacattgagagcaaaggactgcagcccgccccc
atgactctggtattcggctgccgatgctcgcaactcgaccatctctaccgcgacgaggtg
caagacgcccagcagcgcggggtgtttggccgcgtcctcaccgccttctcccgggaaccc
gacagccccaagacctacgtgcaggacgtcctgaggactgagctggctgctgaggtgcac
cgcgtgctgtgcctcgagaggggccacatgtttgtctgcggcgatgtcaccatggcaacc
agcgtcctgcaaactgtgcagcgaatcctagcgacagagggcgacatggagttggacgag
gcgggtgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttcggg
ctcactctgcgcactcaagaagtgacaagccgcatacgcacccagagcttttccctgcag
gagcgacagctgcggggcgcagtgccctgggcgtttgacccaccaggctcagacaccctc
tacccttga
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integrated database retrieval system
