Marmota marmota marmota (Alpine marmot): 107152089
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Entry
107152089 CDS
T09644
Symbol
Hspa5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma03060
Protein export
mmma04141
Protein processing in endoplasmic reticulum
mmma04612
Antigen processing and presentation
mmma04918
Thyroid hormone synthesis
mmma05012
Parkinson disease
mmma05014
Amyotrophic lateral sclerosis
mmma05020
Prion disease
mmma05022
Pathways of neurodegeneration - multiple diseases
mmma05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
107152089 (Hspa5)
04141 Protein processing in endoplasmic reticulum
107152089 (Hspa5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
107152089 (Hspa5)
09152 Endocrine system
04918 Thyroid hormone synthesis
107152089 (Hspa5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
107152089 (Hspa5)
05014 Amyotrophic lateral sclerosis
107152089 (Hspa5)
05020 Prion disease
107152089 (Hspa5)
05022 Pathways of neurodegeneration - multiple diseases
107152089 (Hspa5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
107152089 (Hspa5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
mmma03110
]
107152089 (Hspa5)
04131 Membrane trafficking [BR:
mmma04131
]
107152089 (Hspa5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmma04147
]
107152089 (Hspa5)
Enzymes [BR:
mmma01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
107152089 (Hspa5)
Chaperones and folding catalysts [BR:
mmma03110
]
Heat shock proteins
HSP70 / DNAK
107152089 (Hspa5)
Membrane trafficking [BR:
mmma04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
107152089 (Hspa5)
Autophagy
ER-phagy
ER stress-related proteins
107152089 (Hspa5)
Exosome [BR:
mmma04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
107152089 (Hspa5)
Exosomal proteins of other body fluids (saliva and urine)
107152089 (Hspa5)
Exosomal proteins of colorectal cancer cells
107152089 (Hspa5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
107152089
NCBI-ProteinID:
XP_015353076
Ensembl:
ENSMMMG00000017949
UniProt:
A0A8C5ZVB4
LinkDB
All DBs
Position
Unknown
AA seq
655 aa
AA seq
DB search
MKLSLVAAVLLLLLCAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKRLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTSERDEL
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctctctggtggccgcggtgctgctgctgctgctctgcgcggcgcgggccgag
gaggaggacaagaaggaggatgtgggtaccgtggtcggcatcgacctggggaccacttac
tcctgcgtcggggtgttcaagaatggccgcgtggagatcatcgccaacgatcagggcaac
cgcatcacgccgtcttatgtggccttcacccctgaaggggaacgtctgatcggcgatgcg
gccaagaatcagctcacttccaatcctgagaacacggtcttcgacgccaagcggctcatc
ggccgcacttggaatgacccgtcggtgcagcaagacatcaagttcttgcctttcaaggtg
gttgaaaagaaaactaaaccatacattcaggttgatattggaggtgggcaaactaagaca
tttgctccagaagaaatttctgctatggttctcactaaaatgaaagagactgctgaggct
tatttgggaaagaaggttacccatgcagttgttactgtaccagcctattttaatgatgcc
cagcggcaagcaacaaaagatgctggaactattgctggcctgaatgttatgaggatcatc
aatgagcctacagcagctgctattgcttatggcctggataagagggagggagagaagaac
atcctagtgtttgatttgggtggtggaaccttcgatgtgtctcttctcaccattgacaat
ggtgtcttcgaagtcgtggccactaatggagatactcatctgggtggagaagactttgac
cagcgtgttatggaacacttcatcaagctgtacaaaaagaagactggcaaagatgttagg
aaagacaacagagctgtgcagaaactccggcgtgaagtagaaaaggccaagcgggccctg
tcttctcaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttttct
gaaaccttgactcgggccaaatttgaagagctaaacatggacctgttccggtctaccatg
aagcctgttcagaaagtactggaggattctgacttgaagaagtctgatattgatgagatt
gttcttgttggtggctctactcgaattccaaagattcagcaacttgttaaagagtttttc
aatggcaaggagccatcccgtggcataaacccagatgaagctgttgcatatggtgctgct
gtccaggctggtgtactctctggtgatcaagatacaggtgacctagtactgcttgatgta
tgtcccctgacacttggtattgaaactgtgggaggtgtcatgaccaaactgataccaagg
aacactgtggtacccactaagaagtctcagatcttttctacagcttctgataatcaacct
actgttacaatcaaggtctatgaaggtgaacgacccctgacaaaagacaaccaccttctg
ggtacatttgatctcactggaattcctcctgctccccgtggggtcccccagattgaagtc
acttttgagatagatgtgaatggtattcttcgggtgacagctgaagacaagggtacaggg
aacaaaaataagatcacaattaccaatgatcaaaatcgcttgacacctgaagaaatcgaa
aggatggttaatgatgctgagaagtttgctgaggaagacaaaagactcaaggagcgcatt
gataccaggaatgagttggaaagctatgcctattctctaaagaatcagattggagataaa
gaaaagttgggaggcaaactttcctctgaagataaggagaccatggaaaaagctgtagag
gaaaaaattgaatggctggaaagccaccaagatgctgacattgaagacttcaaagctaaa
aagaaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggc
cctcccccgactggtgaagaggatacatcagaaagagacgagttgtag
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