Marmota marmota marmota (Alpine marmot): 107153644
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Entry
107153644 CDS
T09644
Symbol
Mapk10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma01522
Endocrine resistance
mmma04010
MAPK signaling pathway
mmma04012
ErbB signaling pathway
mmma04014
Ras signaling pathway
mmma04024
cAMP signaling pathway
mmma04068
FoxO signaling pathway
mmma04071
Sphingolipid signaling pathway
mmma04137
Mitophagy - animal
mmma04140
Autophagy - animal
mmma04141
Protein processing in endoplasmic reticulum
mmma04210
Apoptosis
mmma04215
Apoptosis - multiple species
mmma04217
Necroptosis
mmma04310
Wnt signaling pathway
mmma04380
Osteoclast differentiation
mmma04510
Focal adhesion
mmma04517
IgSF CAM signaling
mmma04530
Tight junction
mmma04620
Toll-like receptor signaling pathway
mmma04621
NOD-like receptor signaling pathway
mmma04622
RIG-I-like receptor signaling pathway
mmma04625
C-type lectin receptor signaling pathway
mmma04657
IL-17 signaling pathway
mmma04658
Th1 and Th2 cell differentiation
mmma04659
Th17 cell differentiation
mmma04660
T cell receptor signaling pathway
mmma04664
Fc epsilon RI signaling pathway
mmma04668
TNF signaling pathway
mmma04722
Neurotrophin signaling pathway
mmma04723
Retrograde endocannabinoid signaling
mmma04728
Dopaminergic synapse
mmma04750
Inflammatory mediator regulation of TRP channels
mmma04910
Insulin signaling pathway
mmma04912
GnRH signaling pathway
mmma04914
Progesterone-mediated oocyte maturation
mmma04917
Prolactin signaling pathway
mmma04920
Adipocytokine signaling pathway
mmma04926
Relaxin signaling pathway
mmma04930
Type II diabetes mellitus
mmma04931
Insulin resistance
mmma04932
Non-alcoholic fatty liver disease
mmma04933
AGE-RAGE signaling pathway in diabetic complications
mmma04935
Growth hormone synthesis, secretion and action
mmma04936
Alcoholic liver disease
mmma05010
Alzheimer disease
mmma05012
Parkinson disease
mmma05016
Huntington disease
mmma05017
Spinocerebellar ataxia
mmma05020
Prion disease
mmma05022
Pathways of neurodegeneration - multiple diseases
mmma05132
Salmonella infection
mmma05133
Pertussis
mmma05135
Yersinia infection
mmma05142
Chagas disease
mmma05145
Toxoplasmosis
mmma05152
Tuberculosis
mmma05161
Hepatitis B
mmma05162
Measles
mmma05166
Human T-cell leukemia virus 1 infection
mmma05167
Kaposi sarcoma-associated herpesvirus infection
mmma05169
Epstein-Barr virus infection
mmma05170
Human immunodeficiency virus 1 infection
mmma05171
Coronavirus disease - COVID-19
mmma05200
Pathways in cancer
mmma05208
Chemical carcinogenesis - reactive oxygen species
mmma05210
Colorectal cancer
mmma05212
Pancreatic cancer
mmma05231
Choline metabolism in cancer
mmma05415
Diabetic cardiomyopathy
mmma05417
Lipid and atherosclerosis
mmma05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
107153644 (Mapk10)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
107153644 (Mapk10)
04012 ErbB signaling pathway
107153644 (Mapk10)
04014 Ras signaling pathway
107153644 (Mapk10)
04310 Wnt signaling pathway
107153644 (Mapk10)
04668 TNF signaling pathway
107153644 (Mapk10)
04068 FoxO signaling pathway
107153644 (Mapk10)
04071 Sphingolipid signaling pathway
107153644 (Mapk10)
04024 cAMP signaling pathway
107153644 (Mapk10)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
107153644 (Mapk10)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
107153644 (Mapk10)
04137 Mitophagy - animal
107153644 (Mapk10)
09143 Cell growth and death
04210 Apoptosis
107153644 (Mapk10)
04215 Apoptosis - multiple species
107153644 (Mapk10)
04217 Necroptosis
107153644 (Mapk10)
09144 Cellular community - eukaryotes
04510 Focal adhesion
107153644 (Mapk10)
04530 Tight junction
107153644 (Mapk10)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
107153644 (Mapk10)
04621 NOD-like receptor signaling pathway
107153644 (Mapk10)
04622 RIG-I-like receptor signaling pathway
107153644 (Mapk10)
04625 C-type lectin receptor signaling pathway
107153644 (Mapk10)
04660 T cell receptor signaling pathway
107153644 (Mapk10)
04658 Th1 and Th2 cell differentiation
107153644 (Mapk10)
04659 Th17 cell differentiation
107153644 (Mapk10)
04657 IL-17 signaling pathway
107153644 (Mapk10)
04664 Fc epsilon RI signaling pathway
107153644 (Mapk10)
09152 Endocrine system
04910 Insulin signaling pathway
107153644 (Mapk10)
04920 Adipocytokine signaling pathway
107153644 (Mapk10)
04912 GnRH signaling pathway
107153644 (Mapk10)
04914 Progesterone-mediated oocyte maturation
107153644 (Mapk10)
04917 Prolactin signaling pathway
107153644 (Mapk10)
04926 Relaxin signaling pathway
107153644 (Mapk10)
04935 Growth hormone synthesis, secretion and action
107153644 (Mapk10)
09156 Nervous system
04728 Dopaminergic synapse
107153644 (Mapk10)
04723 Retrograde endocannabinoid signaling
107153644 (Mapk10)
04722 Neurotrophin signaling pathway
107153644 (Mapk10)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
107153644 (Mapk10)
09158 Development and regeneration
04380 Osteoclast differentiation
107153644 (Mapk10)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107153644 (Mapk10)
05208 Chemical carcinogenesis - reactive oxygen species
107153644 (Mapk10)
05231 Choline metabolism in cancer
107153644 (Mapk10)
09162 Cancer: specific types
05210 Colorectal cancer
107153644 (Mapk10)
05212 Pancreatic cancer
107153644 (Mapk10)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
107153644 (Mapk10)
05170 Human immunodeficiency virus 1 infection
107153644 (Mapk10)
05161 Hepatitis B
107153644 (Mapk10)
05171 Coronavirus disease - COVID-19
107153644 (Mapk10)
05162 Measles
107153644 (Mapk10)
05167 Kaposi sarcoma-associated herpesvirus infection
107153644 (Mapk10)
05169 Epstein-Barr virus infection
107153644 (Mapk10)
09171 Infectious disease: bacterial
05132 Salmonella infection
107153644 (Mapk10)
05135 Yersinia infection
107153644 (Mapk10)
05133 Pertussis
107153644 (Mapk10)
05152 Tuberculosis
107153644 (Mapk10)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
107153644 (Mapk10)
05142 Chagas disease
107153644 (Mapk10)
09164 Neurodegenerative disease
05010 Alzheimer disease
107153644 (Mapk10)
05012 Parkinson disease
107153644 (Mapk10)
05016 Huntington disease
107153644 (Mapk10)
05017 Spinocerebellar ataxia
107153644 (Mapk10)
05020 Prion disease
107153644 (Mapk10)
05022 Pathways of neurodegeneration - multiple diseases
107153644 (Mapk10)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
107153644 (Mapk10)
05418 Fluid shear stress and atherosclerosis
107153644 (Mapk10)
05415 Diabetic cardiomyopathy
107153644 (Mapk10)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
107153644 (Mapk10)
04936 Alcoholic liver disease
107153644 (Mapk10)
04932 Non-alcoholic fatty liver disease
107153644 (Mapk10)
04931 Insulin resistance
107153644 (Mapk10)
04933 AGE-RAGE signaling pathway in diabetic complications
107153644 (Mapk10)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
107153644 (Mapk10)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107153644 (Mapk10)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
107153644 (Mapk10)
Protein kinases [BR:
mmma01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
107153644 (Mapk10)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
APH
FTA2
Motif
Other DBs
NCBI-GeneID:
107153644
NCBI-ProteinID:
XP_015354662
Ensembl:
ENSMMMG00000003638
LinkDB
All DBs
Position
Unknown
AA seq
464 aa
AA seq
DB search
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMSSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgagccttcatttcttatactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggatttgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagtggacaaccaattctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatctaaagcctattggctctggggctcagggaatagtttgtgct
gcatatgatgctgtccttgacagaaatgtggccattaagaagctcagccggccatttcag
aaccaaacacatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaatattattagtttattaaatgtcttcacaccccagaaaacgctggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcatctc
cactctgctgggattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgcacattgaaaatccttgactttggactggccaggacagcaggcacaagcttcatgatg
accccttatgtggtgacacgttattacagagcccctgaggtcatcctgggaatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaataaggtaattgagcaactagga
acaccttgcccggaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactctgagcacaataaacttaaagccagccaagccagggatttgttgtcaaagatgcta
gtgattgacccagccaagaggatatcagtggatgacgccttacagcacccttacatcaac
gtctggtacgatcctgctgaagtggaggcgcctccacctcagatatatgacaaacagctg
gatgaaagagagcacaccattgaagaatggaaagaacttatttacaaggaagtgatgagt
tcagaagaaaagactaaaaatggcgtagtaaaaggacaaccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcctcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcggcgggacccctg
ggttgttgcaggtga
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