Marmota marmota marmota (Alpine marmot): 107154413
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Entry
107154413 CDS
T09644
Symbol
Plce1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00562
Inositol phosphate metabolism
mmma01100
Metabolic pathways
mmma04014
Ras signaling pathway
mmma04015
Rap1 signaling pathway
mmma04020
Calcium signaling pathway
mmma04024
cAMP signaling pathway
mmma04070
Phosphatidylinositol signaling system
mmma04919
Thyroid hormone signaling pathway
mmma04933
AGE-RAGE signaling pathway in diabetic complications
mmma05205
Proteoglycans in cancer
Module
mmma_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
107154413 (Plce1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
107154413 (Plce1)
04015 Rap1 signaling pathway
107154413 (Plce1)
04020 Calcium signaling pathway
107154413 (Plce1)
04070 Phosphatidylinositol signaling system
107154413 (Plce1)
04024 cAMP signaling pathway
107154413 (Plce1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
107154413 (Plce1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
107154413 (Plce1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
107154413 (Plce1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmma04131
]
107154413 (Plce1)
Enzymes [BR:
mmma01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
107154413 (Plce1)
Membrane trafficking [BR:
mmma04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
107154413 (Plce1)
Endocytosis
Macropinocytosis
Phospholipase C
107154413 (Plce1)
BRITE hierarchy
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
NUP50
Motif
Other DBs
NCBI-GeneID:
107154413
NCBI-ProteinID:
XP_015355516
Ensembl:
ENSMMMG00000016548
LinkDB
All DBs
Position
Unknown
AA seq
2300 aa
AA seq
DB search
MTSEEMAASVLIPVTQKKVVSAQVALDENNENSDICIPKAHTVRQAGQTSYTISQQNKLK
EESSGSHLPNVLSIAREKMLSDENSNEKCWEKSMPDSVKNLNISCNNILRNHQRGLPQSH
YYETCNSVTEEGLCLETGIPSPLERKVFPGIKLEIDTPPMSISPSGSHSETIETHRVQPD
SNMAVFNFHYEVDRRMSEAFHTLSENLILDDCGNCIPLPTGEQKQDYTAYTCKLVNLAKN
CDNRNGQLQCDHWDTLNHKYLCFEGSGQKDDVICSSDSICRGDFTESAPTKTFLSHFEDF
PDNCEDTEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLVAWNY
IDQKRNGLSLPCGKVMKPLPTVEIRHSGGRCLSEALWSPIYNAVRRGEETENTVGSLLHF
LPKLPASETVHGGISIGLCLKQCVQDTVCEYRATLQRTSIAQYITGSLLEATTSLGARSG
LLNTFGGATGRMMLKERQPGTSMANSNAFPSSSAGISKELIDLQPLIQFPEEVASILTEQ
EQNIYRKVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTSQSGEHNALEDLVMRFN
EVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQF
MDQSDIETMRSLKDAMAQHESSSEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASG
LMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLE
TEEEDSASEGDSSRKNSLKEKTRWQFIIGDLLDSENDIFEQAKECDHHGSEESQKAFAHG
TELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWTKPTTASPA
STKAKLSALSNTVEPGKFPLLGNAVLSGLVEGVLDLFSAKAVYMGHPSIDIHTVCVQNKL
GSMLLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRRFPDQRQQW
LRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKNAEKPNVQRNNTLGLS
TAKKKKKTLMRGESEEATDDEMATRKVKMYKECRGRSGSDPQDTNEQEESEANAIARPPN
PLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKG
FQSFMVSDSNMSFVEFVELFKSFSIRSRKDLKDLFDVYCVPCNRSGSESAPLYTNLTIEE
NTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIF
GIGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSINMCHQGLMSFEGFARFLMDKDNFAS
KNDESQENLKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWD
GDDGMPIIYHGHTLTTKIPFKDVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFK
TVFGEKLVARFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASM
QAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCTDKLQFEYNEE
IPKRIKKADNSAYNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLST
LNASGSSRGKERKSRKSIFGNNPGRMSPGETATFNKTSGKSSYEGIRQTWEESSSPLNPT
TSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPL
LFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGYGYVLKPPVLWDKNCPMYQKFSPLERD
LDNMEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNE
QFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLF
INSRRMEENSSGSTLPASLMFNTEERKCSQTHRVTVHGVPGPEPFAVFTINGGTKAKQLL
QQILTTEQDTKPIITDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPEEG
YVGRIVLKTQQETIEEKNIIQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQ
DVIQQTLCKAKYSYSILSNPNPGDYVLLEEVVKDMPNKKSSTPKSSQRVLLDQECVFQAQ
SKWKGAGKFILKLKEQVQASREDKRKGISFASELKKLTKSTKQPRGLLSPPQLTVSENVQ
NKEEKPVGGLFSSDTMDYRQ
NT seq
6903 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttccgttcttatccctgtgactcagaaaaaagtggtg
tctgcccaggtggccctagatgaaaataatgaaaactctgacatctgtattccaaaggca
catactgtcaggcaagctgggcagacctcttataccatctcacaacagaacaaacttaaa
gaagaatcttctggaagccacttgcctaatgttctctccatagcaagggagaaaatgctt
agtgatgagaacagcaacgaaaagtgctgggagaaaagcatgccagattctgtgaaaaac
cttaacattagctgcaacaacattctgcgaaaccatcagcgtggcctgcctcagagccac
tattatgaaacgtgcaactctgtcacggaggaaggcctgtgtttggaaactggaattcct
tctccactggaaagaaaggtgttccctggaattaaactggaaatagacacacctcccatg
agcattagtccttcaggaagtcactctgagaccatcgagacccacagagtgcagcctgac
agcaacatggcagtatttaattttcattatgaagttgacagaagaatgtcagaggctttc
cataccctatcagaaaacttaattttggacgattgtggaaattgcattccacttcctacg
ggggagcaaaagcaagattacacagcatatacttgtaaactggtaaacttggcaaaaaac
tgtgataacaggaatgggcagctgcagtgtgatcattgggacaccttgaatcataaatac
ctttgctttgagggttcaggccagaaggatgacgtgatatgctctagtgatagcatttgc
aggggggatttcactgaaagtgcacctactaagacttttttgagccattttgaggatttc
cctgataattgtgaagatactgaagaagacttttttaaaagcaaaaaggaacggtccact
ttgttagtcaggagattttgcaaaaatgacagggaagtaaagaaatctgtgtatacgggg
acgagagcaatcatgagaaccctgccttctggccacattggactggttgcttggaattac
attgatcagaaaagaaatggcctctcactgccttgtgggaaagtcatgaaacctctgccc
acagtggagataaggcacagtgggggccgatgtctgtcagaagccctgtggtctccgatc
tacaatgcagtgagaagaggagaagaaacagaaaatacagttggatctcttctccatttc
ttaccaaagcttccagcctctgaaacagtccatggagggattagcattggtctgtgctta
aagcaatgtgtccaagacaccgtgtgtgagtaccgtgccaccctccaaaggacttccata
gctcagtacatcaccggttctctcctggaggcaaccacatctttaggagcaagaagtggc
cttctcaatacttttggaggagccactggacgaatgatgctgaaagaacgccaaccaggt
acctctatggccaattccaatgccttcccttcaagttcagctggaatcagcaaggaactg
atcgatctgcaacccctcatccagttcccagaggaagtcgccagcatcctgacagagcag
gagcagaatatttaccgaaaggtcctgccagtggactacctttgcttcctaacccgggac
ttgggtacaccggaatgccagaggtccctgccgtgcctcaaagcgtccatctcggcgtca
attctcacctctcagagtggagagcacaatgcccttgaggaccttgtgatgcgattcaat
gaggtgagctcctgggtaacatggctgatcctcacagcaggctccatggaggaaaagcgg
gaagtcttctcatatttggtgcatgtggccaagtgctgctggaacatgggcaactacaat
gctgtcatggagttcttggctggcctcaggtcaagaaaagttttaaagatgtggcaattc
atggaccagtctgacatcgagaccatgaggagcctgaaggatgccatggctcagcacgag
tcctcctctgagtacagaaaggtggtgacccgcgcgctgcacatccctggctgcaaggtg
gttccgttctgtggggtgtttctgaaggagctctgtgaagtacttgatggagcctctggc
ctcatgaagctttgcccgcggtacaattcccaagaggagactttagagttcgtagcagat
tacagtggacaagataatttcttgcaacgagtgggacaaaatggcttaaagaattcggag
aaggagtccaccgtcaacagtatctttcagatcatcagaagctgcagtcgaagtctggag
acagaggaggaggacagtgccagtgaaggggacagctctaggaaaaactccctgaaggag
aaaacccgatggcagtttataattggagatttgctggactcagaaaatgacatctttgag
caagccaaagaatgtgatcatcatggatcagaggagtcacagaaggcctttgcccatggg
acagagctcatcccctggtatgtgctgtccatccaagctgatgtgcatcagttcctgctt
cagggggccacggtcatccactatgaccaggacacacacctctctgcccgctgcttcctc
cagcttcagcctgacaatagcactttgacctggacaaagcccaccaccgcctccccagcc
agcactaaggcaaaactcagtgcgctcagtaacaccgtcgagcccggcaaattcccgcta
ctgggcaatgctgtattgagcggcctggtggagggggtcttagatctgttttcagcaaag
gcggtgtacatgggacaccctagcattgatatacacactgtgtgtgttcagaacaaactg
ggtagcatgcttctgtcagagactggtgtgacacttctctatgggcttcaaaccacggac
aatagactattgcactttgtggcaccaaagcacacagctaaaatgctcttcagtggacta
ttggaactcactagagccgtgagaaagatgaggaggttccccgaccaaagacagcagtgg
ctgcggaaacagtatgtgagcctctatcaggaggatggccggtatgaaggcccaaccttg
gctcatgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagccctggg
acatcagcaaagaatgctgagaaacccaatgtgcagcgaaataacaccctgggcctaagc
accgccaagaaaaagaagaaaaccctcatgaggggtgagagtgaagaggcaactgacgat
gagatggcgactcgaaaggtcaaaatgtacaaagagtgtcgaggccggagtggttctgat
cctcaagatacaaatgaacaagaagaatcagaggcgaatgccatcgctaggcctcccaat
cctctcccttccagaagagcccactctttgactacagctgggtcccccaacttggctgcc
gggacgtcatctcccatcaggccagtctcctcccctgtgctgtcttcttcaaacaagagt
ccgtccagtgcctggagcagtagcagctggcacgggcggatcaaaggaggaatgaagggg
ttccagagcttcatggtttcagacagtaacatgagttttgttgaatttgttgagctgttc
aaatcattcagcataaggagccgcaaggacctgaaggatctctttgatgtctactgcgtg
ccctgcaaccgatccggctctgagtcggccccactctacaccaacctgacaattgaggag
aacaccagtgaccttcagcctgacctagatttgttgaccagaaacgtctcagacttgggg
ttgttcattaagagcaaacagcagctttcagacaaccagaggcagatatctgatgccatc
gctgctgcaagcattgtgacaaatggcactgggatcgagagcacatccctgggcatattt
gggattggcattctccagctcaacgacttcctggtgaattgccaaggggaacactgcact
tacgatgagatcctcagcatcatccagaagtttgagcctagtatcaacatgtgtcatcag
ggcctaatgtcatttgaaggatttgcaaggtttctgatggataaagataattttgcctcg
aaaaatgatgagtcacaggagaacttaaaagaattgcagctacccctctcctactattac
attgagtcttcacacaatacctacctcacgggccatcagctcaaaggagaatcctcagta
gaactctacagccaggtcctcttgcaaggctgtaggagcatagagctggactgctgggat
ggagatgatgggatgcccattatttatcatggacatacactgacaaccaagattcctttc
aaggatgtggttgaggccattgatcgcagcgccttcatcaactctgacctgccaatcatc
atatccattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaatttttaag
actgtgtttggagaaaagctggtggctagattcttatttgagactgatttctcagatgat
ccaatgcttccctcacccgaccaacttaggaggaaagtacttcttaaaaacaagaagcta
aaggcccatcagacgcccgtggacatcttaaagcaaaaggctcatcagttagcatccatg
caagcacaggcttataatggtgggaatgccaatcccccacctgccaataatgaggaagag
gaagatgaagaggatgaatatgattatgactatgaatccctttctgatgacaacattctg
gaagacagacctgaaaataaatcatgtactgacaagcttcagtttgagtacaatgaagaa
attcccaagcggataaagaaggcagataactctgcttacaacaaaggaaaggtttatgac
atggaactgggagaagaattttatcttcctcagaataaaaaagaaagcagacagattgca
ccggagctttctgaccttgtcatctattgccaagcagtaaaatttccaggcctgtcaact
ctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggc
aacaatccgggcagaatgagcccaggggagacagcaacatttaacaaaacatctggaaaa
agttcctatgaaggaattcgacagacctgggaggaatcttcttcccctctgaacccaacc
acatccctcagcgctatcattagaactcccaaatgctatcatatctcatcgctgaatgaa
aatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgt
caactgctcaggacctacccggccgccacccgcatcgactcgtccaaccccaatcccctc
ctcttctggctccatgggatccagctcgtggcacttaactaccagacagatgatcttcct
ttacatttaaatgccgccatgtttgaggcaaatggtggctatggttatgtattgaaaccc
ccagttctgtgggacaagaactgccccatgtatcagaagttttctccactggaaagagat
ctagacaacatggagcctgccatctattctttgactattgtctctggccaaaatgtgtgc
cctagtaacagcacaggaagcccgtgcatagaagtggacgtcctgggcatgcccctggat
agctgtcatttccgtacgaagcccatccatcgaaacactctgaaccccatgtggaatgaa
cagtttctgttccgggttcactttgaagatcttgtatttcttcgttttgcagttgtggaa
aataacagttcagcggtaactgctcagaggatcattccactcaaggctttaaaacgagga
tatcgacatcttcagctgcgaaacctccacaatgaagtcttggaaatctctagtttgttt
ataaacagcagaagaatggaagaaaattcctctggcagtaccttgccagcctctttgatg
tttaatacagaagaaagaaaatgttcacagactcacagagtcacagtgcatggggtccca
ggtccagagccctttgctgtctttactataaatggaggcaccaaagccaagcagcttctc
caacagattctgacaactgaacaagacaccaaacctatcatcacagactattttctgatg
gaagaaaaatattttatatctaaagaaaagaatgaatgcaggaaacaaccgttccagaga
gccattggtccagaggaagagatcatgcagattttaagcagctggtttccagaagaaggc
tacgtgggcaggattgtcttaaaaacccagcaggaaaccatagaagagaaaaacattatt
caagatgacaaagaggtgatcttgagctcagaggaggagagtttctttgtccaagtgcat
gatgtttctccagagcaacctcgaacagtaatcaaagcaccccgtgtcagcactgcacag
gatgtcattcagcagacattatgcaaagccaaatattcctacagcatcctgagcaacccc
aacccaggggactatgtgcttttggaagaggtggtcaaagacatgcccaacaagaagtct
tctaccccaaagtcttcacagcgagtccttttggatcaggagtgtgtgtttcaagcccaa
agcaagtggaaaggtgcagggaaattcatccttaagctaaaggagcaggtacaggcatcc
agagaagacaaaagaaagggcatctcttttgcaagtgaacttaagaagctcaccaagtca
actaagcagccccgaggactcctatcacctcctcagctcacagtctcagaaaatgtccaa
aacaaggaggagaaacctgtgggtggcttgttctccagtgatacaatggattatcgacag
tga
DBGET
integrated database retrieval system
