Marmota marmota marmota (Alpine marmot): 107156718 Help Entry 107156718         CDS       T09644                                  Symbol Pklr Name (RefSeq) pyruvate kinase PKLR isoform X1   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma00010   Glycolysis / Gluconeogenesis mmma00620   Pyruvate metabolism mmma01100   Metabolic pathways mmma01200   Carbon metabolism mmma01230   Biosynthesis of amino acids mmma04910   Insulin signaling pathway mmma04930   Type II diabetes mellitus mmma04932   Non-alcoholic fatty liver disease mmma04950   Maturity onset diabetes of the young Module mmma_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mmma_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:mmma00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     107156718 (Pklr)    00620 Pyruvate metabolism     107156718 (Pklr)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     107156718 (Pklr)    04950 Maturity onset diabetes of the young     107156718 (Pklr)    04932 Non-alcoholic fatty liver disease     107156718 (Pklr)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:mmma04147]     107156718 (Pklr) Enzymes [BR:mmma01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      107156718 (Pklr) Exosome [BR:mmma04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    107156718 (Pklr) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  107156718 NCBI-ProteinID:  XP_015358259 Ensembl:  ENSMMMG00000014412 UniProt:  A0A8C5ZP66 LinkDB All DBs Position Unknown AA seq 574 aa AA seqDB search MSVQENIPPQQLRSWISQSQKDLAMSVLIGAPGGPAGYLRRASVAQLTQELGTAFFQKQQ LSAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPTSRSVERLKEMIKAGMNIARLNFS HGSHEYHAESIANIREAVESFATSPLSYRPVAIALDTKGPEIRTGILQGGPQCEVEIVKG SQVLVTVDPAFRTRGDANTVWVDYPNILRVVPVGGRIFIDDGLISLVVQNIGPEGLVTEV ENGGVLGSRKGVNLPGAEVDLPGLSEQDALDLRFGVEHGVDIVFASFVRKASDVTAVRAA LGPEGQSIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGHFPVEAVKM QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTTTGRS AQLLSRYRPRAPVIAVTRSAQAARQVNLCRGVFPLLYREPPEAIWADDVDRRVQFGIQSG KLRGFLRIGDLVIVVTGWRPGSGYTNIMRVLSIS NT seq 1725 nt NT seq  +upstreamnt  +downstreamnt atgtcagtccaggagaacattccaccccagcagcttaggtcatggatctcgcagtcccaa aaagacttagcaatgtctgtcctaatcggggctccaggagggccagcaggatatctgcgg cgcgccagcgtggcccagctgacccaggagctgggcacggccttcttccagaagcagcag ctgtctgccgcgatggcagacaccttcctggaacatctctgcctgctggatattgactcc gagcctgtggctgctcgaagcaccagcatcatcgccaccatcgggcccacatctcgctca gtggagcgcctcaaggagatgatcaaggccgggatgaacattgcaagactcaacttctcc catggctcccacgagtaccacgctgagtccatcgccaacatccgggaggcagtggagagc tttgcaacttccccgctcagctaccggccagtggccatcgctctggacaccaagggaccg gagatacgtactggaatcctgcaggggggtccgcagtgcgaagtggagatagtgaagggc tcccaagtgctggtgactgtggacccggcgttccggacgcggggggacgcgaacaccgtg tgggtggactaccccaatatcctccgggttgtgccggtggggggccgcatcttcattgac gatggactcatctccctagtggtccagaacatcggcccagagggactagtaaccgaagtg gagaatggtggcgttctgggcagcagaaagggcgtaaacttgccaggtgccgaggttgac ctgcctgggctgtctgagcaagacgccttggacctgcgcttcggggtggagcatggtgtg gacatcgtctttgcctcctttgtgcggaaagctagcgatgtgactgcagttcgggctgct ctggggccagagggacagagcatcaaaatcatcagcaaaatcgagaaccacgaaggcgtg aagaagtttgatgaaatcctggaggtgagcgatggtatcatggtagcacggggagacctg ggcatcgaaatcccagctgagaaggttttcctggctcagaagatgatgattgggcggtgc aacttggcaggcaagcccgtcgtctgcgccactcagatgctggagagcatgattactaag ccccggccaacacgggccgagaccagcgatgtggccaatgctgtactggatggggcagac tgcatcatgctgtcaggggagactgccaaaggccacttccccgtggaggccgtaaagatg cagcacgcgattgcacgggaggccgaggccgcggtgtaccaccggcaattgtttgaggag ctgcgcagggcagcgccactgagtcgtgaccccactgaggtgactgccatcggggctgtg gaggcctctttcaagtgctgtgctgctgccatcatcgttctgaccactactggccgctcg gcccagcttctgtctcggtaccgacctcgagccccagtcattgctgtcacccgctccgcc caggctgcccgccaggtcaacctatgccgaggagtcttccccttgctctacagagaacct ccagaggccatctgggcagacgatgtggatcgccgggtccaatttggcattcagagtgga aagctccgtggttttctccgaattggggacctggtgattgtggtgacaggctggcgacct ggctctggctataccaacatcatgcgagtgctgagcatatcctga

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