Marmota marmota marmota (Alpine marmot): 107157108 Help Entry 107157108         CDS       T09644                                  Symbol Hras Name (RefSeq) GTPase HRas isoform X1   KO K02833   GTPase HRas Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma01521   EGFR tyrosine kinase inhibitor resistance mmma01522   Endocrine resistance mmma04010   MAPK signaling pathway mmma04012   ErbB signaling pathway mmma04014   Ras signaling pathway mmma04015   Rap1 signaling pathway mmma04062   Chemokine signaling pathway mmma04068   FoxO signaling pathway mmma04071   Sphingolipid signaling pathway mmma04072   Phospholipase D signaling pathway mmma04137   Mitophagy - animal mmma04140   Autophagy - animal mmma04144   Endocytosis mmma04150   mTOR signaling pathway mmma04151   PI3K-Akt signaling pathway mmma04210   Apoptosis mmma04211   Longevity regulating pathway mmma04213   Longevity regulating pathway - multiple species mmma04218   Cellular senescence mmma04360   Axon guidance mmma04370   VEGF signaling pathway mmma04371   Apelin signaling pathway mmma04510   Focal adhesion mmma04540   Gap junction mmma04550   Signaling pathways regulating pluripotency of stem cells mmma04625   C-type lectin receptor signaling pathway mmma04630   JAK-STAT signaling pathway mmma04650   Natural killer cell mediated cytotoxicity mmma04660   T cell receptor signaling pathway mmma04662   B cell receptor signaling pathway mmma04664   Fc epsilon RI signaling pathway mmma04714   Thermogenesis mmma04720   Long-term potentiation mmma04722   Neurotrophin signaling pathway mmma04725   Cholinergic synapse mmma04726   Serotonergic synapse mmma04730   Long-term depression mmma04810   Regulation of actin cytoskeleton mmma04910   Insulin signaling pathway mmma04912   GnRH signaling pathway mmma04915   Estrogen signaling pathway mmma04916   Melanogenesis mmma04917   Prolactin signaling pathway mmma04919   Thyroid hormone signaling pathway mmma04921   Oxytocin signaling pathway mmma04926   Relaxin signaling pathway mmma04929   GnRH secretion mmma04933   AGE-RAGE signaling pathway in diabetic complications mmma04935   Growth hormone synthesis, secretion and action mmma05010   Alzheimer disease mmma05022   Pathways of neurodegeneration - multiple diseases mmma05034   Alcoholism mmma05132   Salmonella infection mmma05160   Hepatitis C mmma05161   Hepatitis B mmma05163   Human cytomegalovirus infection mmma05165   Human papillomavirus infection mmma05166   Human T-cell leukemia virus 1 infection mmma05167   Kaposi sarcoma-associated herpesvirus infection mmma05170   Human immunodeficiency virus 1 infection mmma05200   Pathways in cancer mmma05203   Viral carcinogenesis mmma05205   Proteoglycans in cancer mmma05206   MicroRNAs in cancer mmma05207   Chemical carcinogenesis - receptor activation mmma05208   Chemical carcinogenesis - reactive oxygen species mmma05210   Colorectal cancer mmma05211   Renal cell carcinoma mmma05213   Endometrial cancer mmma05214   Glioma mmma05215   Prostate cancer mmma05216   Thyroid cancer mmma05218   Melanoma mmma05219   Bladder cancer mmma05220   Chronic myeloid leukemia mmma05221   Acute myeloid leukemia mmma05223   Non-small cell lung cancer mmma05224   Breast cancer mmma05225   Hepatocellular carcinoma mmma05226   Gastric cancer mmma05230   Central carbon metabolism in cancer mmma05231   Choline metabolism in cancer mmma05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mmma05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mmma00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     107157108 (Hras)    04012 ErbB signaling pathway     107157108 (Hras)    04014 Ras signaling pathway     107157108 (Hras)    04015 Rap1 signaling pathway     107157108 (Hras)    04370 VEGF signaling pathway     107157108 (Hras)    04371 Apelin signaling pathway     107157108 (Hras)    04630 JAK-STAT signaling pathway     107157108 (Hras)    04068 FoxO signaling pathway     107157108 (Hras)    04072 Phospholipase D signaling pathway     107157108 (Hras)    04071 Sphingolipid signaling pathway     107157108 (Hras)    04151 PI3K-Akt signaling pathway     107157108 (Hras)    04150 mTOR signaling pathway     107157108 (Hras)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     107157108 (Hras)    04140 Autophagy - animal     107157108 (Hras)    04137 Mitophagy - animal     107157108 (Hras)   09143 Cell growth and death    04210 Apoptosis     107157108 (Hras)    04218 Cellular senescence     107157108 (Hras)   09144 Cellular community - eukaryotes    04510 Focal adhesion     107157108 (Hras)    04540 Gap junction     107157108 (Hras)    04550 Signaling pathways regulating pluripotency of stem cells     107157108 (Hras)   09142 Cell motility    04810 Regulation of actin cytoskeleton     107157108 (Hras)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     107157108 (Hras)    04650 Natural killer cell mediated cytotoxicity     107157108 (Hras)    04660 T cell receptor signaling pathway     107157108 (Hras)    04662 B cell receptor signaling pathway     107157108 (Hras)    04664 Fc epsilon RI signaling pathway     107157108 (Hras)    04062 Chemokine signaling pathway     107157108 (Hras)   09152 Endocrine system    04910 Insulin signaling pathway     107157108 (Hras)    04929 GnRH secretion     107157108 (Hras)    04912 GnRH signaling pathway     107157108 (Hras)    04915 Estrogen signaling pathway     107157108 (Hras)    04917 Prolactin signaling pathway     107157108 (Hras)    04921 Oxytocin signaling pathway     107157108 (Hras)    04926 Relaxin signaling pathway     107157108 (Hras)    04935 Growth hormone synthesis, secretion and action     107157108 (Hras)    04919 Thyroid hormone signaling pathway     107157108 (Hras)    04916 Melanogenesis     107157108 (Hras)   09156 Nervous system    04725 Cholinergic synapse     107157108 (Hras)    04726 Serotonergic synapse     107157108 (Hras)    04720 Long-term potentiation     107157108 (Hras)    04730 Long-term depression     107157108 (Hras)    04722 Neurotrophin signaling pathway     107157108 (Hras)   09158 Development and regeneration    04360 Axon guidance     107157108 (Hras)   09149 Aging    04211 Longevity regulating pathway     107157108 (Hras)    04213 Longevity regulating pathway - multiple species     107157108 (Hras)   09159 Environmental adaptation    04714 Thermogenesis     107157108 (Hras)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107157108 (Hras)    05206 MicroRNAs in cancer     107157108 (Hras)    05205 Proteoglycans in cancer     107157108 (Hras)    05207 Chemical carcinogenesis - receptor activation     107157108 (Hras)    05208 Chemical carcinogenesis - reactive oxygen species     107157108 (Hras)    05203 Viral carcinogenesis     107157108 (Hras)    05230 Central carbon metabolism in cancer     107157108 (Hras)    05231 Choline metabolism in cancer     107157108 (Hras)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     107157108 (Hras)   09162 Cancer: specific types    05210 Colorectal cancer     107157108 (Hras)    05225 Hepatocellular carcinoma     107157108 (Hras)    05226 Gastric cancer     107157108 (Hras)    05214 Glioma     107157108 (Hras)    05216 Thyroid cancer     107157108 (Hras)    05221 Acute myeloid leukemia     107157108 (Hras)    05220 Chronic myeloid leukemia     107157108 (Hras)    05218 Melanoma     107157108 (Hras)    05211 Renal cell carcinoma     107157108 (Hras)    05219 Bladder cancer     107157108 (Hras)    05215 Prostate cancer     107157108 (Hras)    05213 Endometrial cancer     107157108 (Hras)    05224 Breast cancer     107157108 (Hras)    05223 Non-small cell lung cancer     107157108 (Hras)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107157108 (Hras)    05170 Human immunodeficiency virus 1 infection     107157108 (Hras)    05161 Hepatitis B     107157108 (Hras)    05160 Hepatitis C     107157108 (Hras)    05163 Human cytomegalovirus infection     107157108 (Hras)    05167 Kaposi sarcoma-associated herpesvirus infection     107157108 (Hras)    05165 Human papillomavirus infection     107157108 (Hras)   09171 Infectious disease: bacterial    05132 Salmonella infection     107157108 (Hras)   09164 Neurodegenerative disease    05010 Alzheimer disease     107157108 (Hras)    05022 Pathways of neurodegeneration - multiple diseases     107157108 (Hras)   09165 Substance dependence    05034 Alcoholism     107157108 (Hras)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     107157108 (Hras)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     107157108 (Hras)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     107157108 (Hras)    01522 Endocrine resistance     107157108 (Hras)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mmma04131]     107157108 (Hras)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:mmma04147]     107157108 (Hras)    04031 GTP-binding proteins [BR:mmma04031]     107157108 (Hras) Membrane trafficking [BR:mmma04131]  Exocytosis   Small GTPases and associated proteins    Other small GTPases and associated proteins     107157108 (Hras)  Endocytosis   Macropinocytosis    Ras GTPases     107157108 (Hras) Exosome [BR:mmma04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    107157108 (Hras)   Exosomal proteins of colorectal cancer cells    107157108 (Hras) GTP-binding proteins [BR:mmma04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     107157108 (Hras) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 Septin Ldh_1_N DUF6974 Motif Other DBs NCBI-GeneID:  107157108 NCBI-ProteinID:  XP_015358889 Ensembl:  ENSMMMG00000007032 UniProt:  A0A8C5Z4H2 LinkDB All DBs Position Unknown AA seq 197 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL AARTVESRQAQDLARSYGIPYIETSAKTRQGSRSGFGSSSGTLWDPRDPCDPAAPTLVWR MPSTRWCGRFGSTNCGS NT seq 594 nt NT seq  +upstreamnt  +downstreamnt atgacggagtataagcttgtggtggtgggcgctggaggcgtggggaaaagtgcgctgacc atccagctgatccagaaccactttgtggacgagtacgaccccaccatagaggactcctac cggaagcaagtggtcatcgatggggagacatgcctgctggacatcttggacacagcgggc caggaagaatacagtgccatgcgggaccagtacatgcgcactggggagggcttcctctgt gtgtttgccatcaacaacaccaagtcctttgaggacatccatcagtatagggagcagatt aagcgggtgaaggactcggatgatgtgcccatggtgctggtggggaacaaatgtgacctg gccgcgcgtaccgtggagtctcggcaggcccaggatcttgcccgaagctatggcattccc tacattgagacatcagccaagacccggcagggcagccgctctggctttggctccagctcc gggaccctctgggacccccgggacccatgtgacccagcggcccccacgctggtgtggagg atgccttctacacgctggtgcgggagattcggcagcacaaactgcggaagctga

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