Marmota marmota marmota (Alpine marmot): 107157604
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Entry
107157604 CDS
T09644
Symbol
Syk
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
KO
K05855
spleen tyrosine kinase [EC:
2.7.10.2
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma04064
NF-kappa B signaling pathway
mmma04072
Phospholipase D signaling pathway
mmma04151
PI3K-Akt signaling pathway
mmma04380
Osteoclast differentiation
mmma04611
Platelet activation
mmma04613
Neutrophil extracellular trap formation
mmma04625
C-type lectin receptor signaling pathway
mmma04650
Natural killer cell mediated cytotoxicity
mmma04662
B cell receptor signaling pathway
mmma04664
Fc epsilon RI signaling pathway
mmma04666
Fc gamma R-mediated phagocytosis
mmma05152
Tuberculosis
mmma05167
Kaposi sarcoma-associated herpesvirus infection
mmma05168
Herpes simplex virus 1 infection
mmma05169
Epstein-Barr virus infection
mmma05171
Coronavirus disease - COVID-19
mmma05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
107157604 (Syk)
04072 Phospholipase D signaling pathway
107157604 (Syk)
04151 PI3K-Akt signaling pathway
107157604 (Syk)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
107157604 (Syk)
04613 Neutrophil extracellular trap formation
107157604 (Syk)
04650 Natural killer cell mediated cytotoxicity
107157604 (Syk)
04662 B cell receptor signaling pathway
107157604 (Syk)
04664 Fc epsilon RI signaling pathway
107157604 (Syk)
04666 Fc gamma R-mediated phagocytosis
107157604 (Syk)
09158 Development and regeneration
04380 Osteoclast differentiation
107157604 (Syk)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
107157604 (Syk)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
107157604 (Syk)
05167 Kaposi sarcoma-associated herpesvirus infection
107157604 (Syk)
05169 Epstein-Barr virus infection
107157604 (Syk)
09171 Infectious disease: bacterial
05152 Tuberculosis
107157604 (Syk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107157604 (Syk)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107157604 (Syk)
Protein kinases [BR:
mmma01001
]
Non-receptor tyrosine kinases
SYK family
107157604 (Syk)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
Kdo
DUF7063
ABC1
SH2_1
RIO1
Motif
Other DBs
NCBI-GeneID:
107157604
NCBI-ProteinID:
XP_015359431
Ensembl:
ENSMMMG00000021952
UniProt:
A0A8C6A4N6
LinkDB
All DBs
Position
Unknown
AA seq
629 aa
AA seq
DB search
MANSPTESANHLPFFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREINGTYAISGGRTHSSPADLCQYHSQESDGLICLLKKPFNRPPGVQPKTGPFE
DLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGNISRDESEQI
VLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGAQMAHQQGPIAHPVSWSAGGIISRIKSYYLPKRDGRKA
SPSHRTRPESTASFNPYEPERGRWAAERGPQIEAMPMDTEVYESPYADPEEIRPKEVYLD
RNLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQ
LDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLE
ECNFVHRDLAARNVLLVTQHYAKISDFGLSKALQADENYYKAQTHGKWPVKWYAPECINY
YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPQGCPREMYDLMN
LCWTYEVEKRPGFVAVELRLRNYYYDVVN
NT seq
1890 nt
NT seq
+upstream
nt +downstream
nt
atggccaacagcccaacagagagcgccaaccacctgcccttcttttttggcaacatcact
cgggaggaggccgaagattacctggtccaggggggcatgacagatgggctctacctgctg
cgtcagagtcgcaattacctgggtggctttgccctgtcggtggctcacggcaggaaggca
caccactataccatcgagagggagatcaatggcacctatgccatctcaggtggcaggacc
cacagcagccctgctgacctctgccagtaccactcccaggaatccgatggcctcatctgc
cttctcaaaaaacccttcaaccgaccccctggagtgcagcccaagacagggcccttcgag
gacctgaaggaaaacctcatcagagaatatgtaaagcagacatggaaccttcagggccag
gctctggaacaggccatcatcagtcagaagccccagctggagaagctgatcgccaccaca
gcccatgaaaaaatgccctggttccatgggaacatctctcgggatgaatctgaacagatt
gtcctgataggatcaaagaccaatggaaaattcttgatcagggcccgagacaataatggc
tcctacgccctgtgcctgctgcacgaagggaaggtgcttcactatcgcatcgacaaggac
aagacagggaagctctccatccctgatggaaagaagttcgacacactctggcagctggtg
gaacattattcttacaagccagatggtttgttaagagttcttacagttccatgtcaaaaa
attggcgcacagatggctcatcaacaaggaccaattgctcatcctgtgagttggtcagcg
ggtggaataatctcaagaatcaaatcatactacttaccaaagcgggacggcagaaaggcc
tccccgtcccacaggacccggccagagagcaccgcgtccttcaacccttatgagccagaa
cgaggacgctgggctgcggagagaggtccccagatagaagccatgcccatggacacagag
gtgtacgagagcccctatgctgaccccgaggagatcaggcccaaggaggtctacctggac
agaaacctgctcactctagaggacaaggaactgggctctggtaacttcgggactgtgaaa
aagggctactaccaaatgaaaaaagtggtgaaaacagtggctgtgaaaatcctgaaaaac
gaggccaatgaccccgccctgaaggatgaattattagcagaagcaaacgtcatgcagcag
ctcgacaacccctacatcgtgcgcatgatcggcatctgtgaagccgagtcctggatgctg
gtcatggagatggcagagcttggtccactcaacaagtatctgcagcagaacaggcacgtc
aaggataagaacatcatagagctggttcatcaggtttccatgggaatgaaatatttggag
gagtgcaattttgtgcacagagatctggctgcaagaaacgtattgctggtcactcaacat
tatgccaagatcagcgactttgggctttccaaagcactgcaagcagacgaaaactactac
aaggcccagacccacgggaagtggcccgtgaagtggtatgcccccgaatgcatcaactac
tacaagttctccagcaaaagcgacgtgtggagcttcggtgtgctgatgtgggaagccttc
tcctatgggcagaagccctatcgagggatgaaaggaagtgaagttaccgccatgttggag
aaaggagagcggatggggtgccctcaagggtgtcccagagagatgtatgatctgatgaac
ctgtgctggacgtacgaggtggagaaaaggcccgggtttgtagcagtggagctgcggctg
cgcaattactactatgacgtggttaactaa
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