Mycolicibacterium moriokaense: MMOR_05050
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Entry
MMOR_05050 CDS
T06887
Symbol
bkdA_1
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
mmor
Mycolicibacterium moriokaense
Pathway
mmor00280
Valine, leucine and isoleucine degradation
mmor00640
Propanoate metabolism
mmor00785
Lipoic acid metabolism
mmor01100
Metabolic pathways
mmor01110
Biosynthesis of secondary metabolites
mmor01210
2-Oxocarboxylic acid metabolism
Module
mmor_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmor00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MMOR_05050 (bkdA_1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MMOR_05050 (bkdA_1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MMOR_05050 (bkdA_1)
Enzymes [BR:
mmor01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MMOR_05050 (bkdA_1)
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GFIT
Motif
Pfam:
E1_dh
Transketolase_C
Transket_pyr
TPP_enzyme_C
PFOR_II
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
BBW99568
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Position
518398..520419
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AA seq
673 aa
AA seq
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MSSSLQNETSSRTGDRALDLYRLMSRVHHGDKRVRKALSSGEAAMSYWPVDGQEAMSAGA
MLALSEGDQLVTTYRGLGDVLAKGIDLRGYFAELLGHRDGLSKGKAGAMGIHDPQHGIAW
TTGIVGAGPLIANGIALAVERRNTGQVVLVSFGDGATSIGFVHEAMNMAAVWSLPVIFLC
QNNSWAEGTAFDRYTRSERLSDRAQGYGMPGVTVDGTDPYAVHDAVAAAVDRARRKQGPT
FVEAVAYRLQGHYFGDAMGYADPEELAAKRADPPFARFRQRLIDEGAAAAADLDAIDAQV
VAELDAAFAAAVKSAPVGVDELTRDVFAANGSEVSDVDQPRFELPGGETEDLGLVQAINR
TLDRAMAADDSIVLLGEDIGDASGGGMFKITAGLSAKYGEDRVLDTPIAESSIIGAAVGA
SLGGLRPVAELMFMDFLGVAMDQIANHAAKVRYMSGGRQGAPMVIRTMVGTAAGPQHSQA
FEAWAMHTPGVKVVWPSTSADAAGLLNACLVDEDPCLFIESMKLYYGGGKGPVPVADYVI
PLGQADVKRSGSDVTVVTYGVMVHAALEAAEQLSAEGISVEVVDLRTLVPLDLPTVLASV
RKTTRLVVAHESVGFCGPGAEIAASVGTELFGVLRAPIQRVAGTYTPVPRAATLEAACRP
GAAQLLETIRRTV
NT seq
2022 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtcttcactgcagaatgaaacgtcgtcgcggacgggtgatcgcgcgctggacctc
taccggcttatgagcagggttcaccacggcgacaagcgtgttcgcaaagcgctgtcgtcc
ggtgaggccgcgatgagttactggcccgtggacggccaggaagcgatgtcagccggcgcg
atgttggcgctgtccgagggtgaccagctggtcacgacgtaccgaggattgggcgatgta
ctggcgaaggggatcgatctccgcggatacttcgccgaattgttaggccaccgggacggg
ctgtcgaaaggcaaagccggcgccatgggcatccacgacccgcaacacgggatcgcctgg
accacgggcatcgtcggcgcagggccgctgatcgcgaacggaatcgcgttggccgtcgaa
cgccggaacaccggacaggtggtactcgtcagcttcggtgacggtgccaccagcatcggc
ttcgtccacgaggcgatgaacatggcggcagtctggtcactgcccgtgatcttcttgtgt
cagaacaactcctgggccgaaggcaccgctttcgatcggtacacgcggtccgaacggttg
tcggaccgagcgcagggttacggcatgccgggagtgaccgtcgacggcaccgacccgtat
gcggtgcacgacgccgtcgcggcggcagtggaccgtgcgcgacgcaagcagggacccacg
ttcgtcgaggccgtcgcctatcggctgcagggccactacttcggtgacgcgatgggttac
gcggacccagaggagctcgctgccaagcgtgcagacccgcccttcgcgcgtttccgtcag
cgcctgatcgatgagggcgcggctgcggccgccgacctggacgcgatcgacgcacaggtc
gtcgcggagctagacgccgcgttcgcggcagccgtcaagtccgccccagtgggcgtcgat
gaactgacccgagatgtgttcgccgctaacggttctgaggtttccgacgttgatcaaccc
cgctttgagctgccgggtggcgagaccgaagatctcggtttggtgcaggcgatcaaccgg
actctggaccgtgccatggccgccgacgattcgatcgtgctgctcggcgaggacatcggc
gatgcctccggcggcgggatgttcaagatcaccgcggggctgtcggccaagtatggtgag
gaccgcgtgctcgacactccgatcgcagagtcgtccattatcggagcagcagttggcgcg
tcgctcggcggactgagaccggtcgccgagttgatgttcatggacttcctaggtgtcgcc
atggatcagatcgccaaccacgccgcgaaggtgcggtatatgtctggcggccgtcagggt
gcgccgatggtgatccggacgatggtgggaactgctgcgggaccccaacattcccaggcc
ttcgaagcgtgggcgatgcacaccccgggggtgaaggtcgtgtggcccagcacctctgcc
gacgccgccggattgcttaacgcgtgtctagtcgatgaggacccctgcctgttcatcgag
tccatgaagctctactacggcggcggaaagggtccggtgccggtggccgattacgttatc
ccgctcggtcaggccgacgtgaagcggtcaggctctgacgtcaccgtcgtgacctacggc
gtcatggtgcacgccgccctcgaagcggcggaacaactttcagccgaagggatctcggtc
gaggtagtggatctgcgcacgctggtgccgctggatctgccgacggtgctggcgtcggta
cgcaagacgacccggctggtcgtcgcgcatgagtcggtcggtttttgtggtcctggcgcc
gagatcgccgcgagcgtgggtacggaactgttcggggtcttgcgcgccccgattcagcgc
gtcgccggtacgtacacccctgtgccgcgcgccgccactctcgaggccgcctgccggccg
ggagccgcccaactgctggagaccatcaggaggaccgtgtga
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