Mus musculus (house mouse): 104110 Help Entry 104110            CDS       T01002                                  Symbol Adcy4, mKIAA4004 Name (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism mmu  Mus musculus (house mouse) Pathway mmu00230   Purine metabolism mmu01100   Metabolic pathways mmu01522   Endocrine resistance mmu04015   Rap1 signaling pathway mmu04020   Calcium signaling pathway mmu04022   cGMP-PKG signaling pathway mmu04024   cAMP signaling pathway mmu04062   Chemokine signaling pathway mmu04072   Phospholipase D signaling pathway mmu04081   Hormone signaling mmu04082   Neuroactive ligand signaling mmu04114   Oocyte meiosis mmu04211   Longevity regulating pathway mmu04213   Longevity regulating pathway - multiple species mmu04261   Adrenergic signaling in cardiomyocytes mmu04270   Vascular smooth muscle contraction mmu04371   Apelin signaling pathway mmu04540   Gap junction mmu04611   Platelet activation mmu04713   Circadian entrainment mmu04714   Thermogenesis mmu04723   Retrograde endocannabinoid signaling mmu04724   Glutamatergic synapse mmu04725   Cholinergic synapse mmu04727   GABAergic synapse mmu04742   Taste transduction mmu04750   Inflammatory mediator regulation of TRP channels mmu04911   Insulin secretion mmu04912   GnRH signaling pathway mmu04913   Ovarian steroidogenesis mmu04914   Progesterone-mediated oocyte maturation mmu04915   Estrogen signaling pathway mmu04916   Melanogenesis mmu04918   Thyroid hormone synthesis mmu04921   Oxytocin signaling pathway mmu04923   Regulation of lipolysis in adipocytes mmu04925   Aldosterone synthesis and secretion mmu04926   Relaxin signaling pathway mmu04927   Cortisol synthesis and secretion mmu04928   Parathyroid hormone synthesis, secretion and action mmu04934   Cushing syndrome mmu04935   Growth hormone synthesis, secretion and action mmu04970   Salivary secretion mmu04971   Gastric acid secretion mmu04972   Pancreatic secretion mmu04976   Bile secretion mmu05032   Morphine addiction mmu05163   Human cytomegalovirus infection mmu05166   Human T-cell leukemia virus 1 infection mmu05200   Pathways in cancer mmu05207   Chemical carcinogenesis - receptor activation mmu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mmu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     104110 (Adcy4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     104110 (Adcy4)    04371 Apelin signaling pathway     104110 (Adcy4)    04020 Calcium signaling pathway     104110 (Adcy4)    04072 Phospholipase D signaling pathway     104110 (Adcy4)    04024 cAMP signaling pathway     104110 (Adcy4)    04022 cGMP-PKG signaling pathway     104110 (Adcy4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     104110 (Adcy4)    04081 Hormone signaling     104110 (Adcy4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     104110 (Adcy4)   09144 Cellular community - eukaryotes    04540 Gap junction     104110 (Adcy4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     104110 (Adcy4)    04062 Chemokine signaling pathway     104110 (Adcy4)   09152 Endocrine system    04911 Insulin secretion     104110 (Adcy4)    04923 Regulation of lipolysis in adipocytes     104110 (Adcy4)    04912 GnRH signaling pathway     104110 (Adcy4)    04913 Ovarian steroidogenesis     104110 (Adcy4)    04915 Estrogen signaling pathway     104110 (Adcy4)    04914 Progesterone-mediated oocyte maturation     104110 (Adcy4)    04921 Oxytocin signaling pathway     104110 (Adcy4)    04926 Relaxin signaling pathway     104110 (Adcy4)    04935 Growth hormone synthesis, secretion and action     104110 (Adcy4)    04918 Thyroid hormone synthesis     104110 (Adcy4)    04928 Parathyroid hormone synthesis, secretion and action     104110 (Adcy4)    04916 Melanogenesis     104110 (Adcy4)    04925 Aldosterone synthesis and secretion     104110 (Adcy4)    04927 Cortisol synthesis and secretion     104110 (Adcy4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     104110 (Adcy4)    04270 Vascular smooth muscle contraction     104110 (Adcy4)   09154 Digestive system    04970 Salivary secretion     104110 (Adcy4)    04971 Gastric acid secretion     104110 (Adcy4)    04972 Pancreatic secretion     104110 (Adcy4)    04976 Bile secretion     104110 (Adcy4)   09156 Nervous system    04724 Glutamatergic synapse     104110 (Adcy4)    04727 GABAergic synapse     104110 (Adcy4)    04725 Cholinergic synapse     104110 (Adcy4)    04723 Retrograde endocannabinoid signaling     104110 (Adcy4)   09157 Sensory system    04742 Taste transduction     104110 (Adcy4)    04750 Inflammatory mediator regulation of TRP channels     104110 (Adcy4)   09149 Aging    04211 Longevity regulating pathway     104110 (Adcy4)    04213 Longevity regulating pathway - multiple species     104110 (Adcy4)   09159 Environmental adaptation    04713 Circadian entrainment     104110 (Adcy4)    04714 Thermogenesis     104110 (Adcy4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104110 (Adcy4)    05207 Chemical carcinogenesis - receptor activation     104110 (Adcy4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     104110 (Adcy4)    05163 Human cytomegalovirus infection     104110 (Adcy4)   09165 Substance dependence    05032 Morphine addiction     104110 (Adcy4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     104110 (Adcy4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     104110 (Adcy4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     104110 (Adcy4) Enzymes [BR:mmu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      104110 (Adcy4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  104110 NCBI-ProteinID:  NP_536683 MGI:  99674 Ensembl:  ENSMUSG00000022220 UniProt:  Q91WF3 LinkDB All DBs Position 14:complement(56006513..56021552) Genome browser AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLILLLVIVLCALVALPAVAWASGRELTSDPS FLTTVLCALGGFSLLLGLASREQQLQRWTRPLSGLIWVALLALGYGFLFTGGVVSAWDQV SFFLFIIFTVYAMLPLGMRDAAAAGVISSLSHLLVLGLYLGWQPESQRALLPQLAANAVL FLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQRSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRVATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVERADTEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAKGLLSSLEGHTMRPSLLMTR YLESWGAAKPFAHLSHLDSPVSTSTPLPEKAFSPQWSLDRSRTPRGLDDELDTGDAKFFQ VIEQLNSQKQWKQSKDFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQM LVTTRPPALIITYSITFLLFFLLLFVCFSEHLTKCVQKGPKMLHWLPALSVLVATRPGFR VALGTATILLVFTMAIASLLFLPVSSDCLFLASNVSSVTFNASWEMPGSLPLISIPLISI PYSMHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLIARLYQSPS DSRPGVLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLT RLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLEC LRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDSERSCSHLGT MVEFAVALGSKLGVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRME STGVLGKIQVTEETARALQSLGYTCYSRGSIKVKGKGELCTYFLNTDLTRTGSPSAS NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccccggcctcctcccagcgaagatctcttctacgaaacttac tacagcctgagccaacagtacccactgctgatactgcttttggtcattgtgctctgcgcg ctggtggcactgcccgccgtcgcctgggccagcggcagggagctgacctcagacccaagc ttcctgacaactgtgctgtgtgctttgggtggcttctctctgctattggggcttgcttcc cgggagcagcaactgcagcgatggacacgacctctttctggtctcatatgggttgcatta ctggctctgggctatggatttctgttcactgggggtgtggtgagcgcctgggaccaggtg tcttttttcctcttcatcatcttcaccgtgtacgccatgctgcccttgggcatgcgggat gctgctgctgcgggagtcatctcatccctctcgcacctgctggtccttggactgtatctt gggtggcagcctgagtcacagagagctctgctaccacagttggcagcaaacgcggtattg ttcctgtgtgggaacgtggtgggagcgtaccacaaggccctgatggagcgagcattgcgg gccacgttccgggaggctcttagctctctgcactcacgccggaggctggacactgagaaa aagcaccaggagcacctcctcttgtctatccttcctgcctacctggcccgagagatgaaa gcagagatcatggcccggctgcaggctggacagcgctcacggccagagaacacaaacaac tttcacagcctgtatgtcaagaggcaccaaggagtgagtgtgctgtatgctgacatcgtg ggcttcacgcggctggccagcgagtgttccccgaaggagctggtgctcatgctgaatgag ctctttggcaagttcgaccaaattgccaaggagcacgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctccgggctgcccctctcgctgcctgaccacgctatcaat tgtgtgcgcatggggctggacatgtgccgggccatcaggaaacttcgggtagccaccggt gtggatatcaacatgcgtgtgggcgtgcactcgggcagcgttctctgtggagtcattggg ctacagaagtggcagtatgatgtctggtcccatgatgtcacattggccaaccatatggaa gcaggcggtgtaccaggacgagtgcacatcacaggggccacgctggccctgctagcagga gcttatgctgtggagagggcagacacggaacaccgagacccataccttcgggagctagga gaacctacatacctggtcattgatcctcgggctgaggaggaagacgagaagggcaccgca aaaggattgctgtcttctctggaggggcacacgatgcgtccgtcactactgatgactcgc tatctggagtcttggggtgcagccaagcctttcgcccacctaagccaccttgacagtccc gtgtccacctccactccactcccggagaaagccttcagcccccagtggagcctggaccgg agtcgcaccccccggggactagatgatgaactggacactggtgatgctaagttcttccag gtcatcgaacaactcaactctcagaaacagtggaagcagtcgaaggacttcaacctcctg acgctgtacttcagagagaaggagatggagaaacagtatcggctctctgcactccccgcc ttcaaatactacgcagcctgcaccttcctggtttttctgtccaacttcactatccaaatg ctggtgacaaccaggcccccagctctgatcatcacctacagcatcaccttccttctcttc tttctcctcctcttcgtctgcttctcagagcacctgacgaagtgtgtccagaaaggtccc aagatgttgcactggctgcctgcactgtctgtcctggtggccacacggccaggatttcga gtagccctgggtacggccaccatcctcctggtattcactatggccatcgccagcctgctc ttcttaccagtgtcatcagactgccttttcctggcttccaatgtgtcatctgtgactttc aatgcttcctgggagatgccaggatccctgcccctcatcagcatccccctcatcagcatc ccatactccatgcattgctgcgtgttgggtttcctctcctgctccctttttctgcacatg agcttcgaactgaagctgctcctacttctgctgtggctggtggcatcttgttccctattt ctgcattcccacgcctggctgtctgactgcctcattgcccgcctttatcaaagcccttcg gactccagaccaggggtactgaaggaacccaagctgatgggagcgatctacttcttcatc ttcttcttcacactcctggtcctggctcggcagaatgagtattactgccgcctggacttc ctgtggaaaaagaaactgaggcaggagcgagaggagactgagacaatggagaacctgacc cggctcctcctggagaatgtactccctgcacacgtggccccccagttcatcggccagaac cggcgcaatgaggacctctaccaccagtcgtacgaatgcgtttgtgtcctcttcgcgtcg gtcccagactttaaggaattctactctgaatccaacatcaaccacgaggggctggagtgc ctgcggctgctcaatgagatcattgctgactttgatgagctgctctccaagccaaagttc agtggagtagagaagatcaaaactattggcagtacctacatggcggccacaggcttaaat gccacctctggacaggatactcagcaggattctgagagaagctgcagtcatctgggcacc atggtggaatttgcagtggccctggggtctaagctgggagtcatcaacaagcactcgttc aataacttccgcctgcgtgtggggttgaaccacggaccagtagtagcaggggtgattggg gcgcagaagccacagtacgacatctgggggaacacagtgaatgtggccagccgaatggag agcacaggcgttctcggcaagatccaagtgactgaggagacagcgcgggccctgcagtcc ctgggttacacgtgctatagcagaggcagcatcaaggtcaaaggcaaaggggaactctgt acctacttcctgaacacagacctgacgcggaccggatctccctcagcatcctag

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