Mus musculus (house mouse): 107476
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Entry
107476 CDS
T01002
Symbol
Acaca, A530025K05Rik, Acac, Acc1, Gm738
Name
(RefSeq) acetyl-Coenzyme A carboxylase alpha
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00061
Fatty acid biosynthesis
mmu00620
Pyruvate metabolism
mmu00640
Propanoate metabolism
mmu01100
Metabolic pathways
mmu01212
Fatty acid metabolism
mmu04152
AMPK signaling pathway
mmu04910
Insulin signaling pathway
mmu04922
Glucagon signaling pathway
mmu04936
Alcoholic liver disease
Module
mmu_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
107476 (Acaca)
00640 Propanoate metabolism
107476 (Acaca)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
107476 (Acaca)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
107476 (Acaca)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
107476 (Acaca)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
107476 (Acaca)
04922 Glucagon signaling pathway
107476 (Acaca)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
107476 (Acaca)
Enzymes [BR:
mmu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
107476 (Acaca)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
107476 (Acaca)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
107476 (Acaca)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
107476
NCBI-ProteinID:
NP_579938
MGI:
108451
Ensembl:
ENSMUSG00000020532
UniProt:
Q5SWU9
LinkDB
All DBs
Position
11:84020461..84292477
Genome browser
AA seq
2345 aa
AA seq
DB search
MDEPSPLAKTLELNQHSRFIIGSVSEDNSEDEISNLVKLDLEEKEGSLSPASVSSDTLSD
LGISGLQDGLAFHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKV
LIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGG
PNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALG
DKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQDLYEKGYVKDVDDGLKAA
EEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQ
ILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAG
TVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYG
VSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYF
SVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETE
SFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVL
PAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGS
SYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAE
IEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQS
TALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQD
IMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVF
FMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDM
NTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRA
RQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHS
NQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMS
FASNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEIMGCFCDSPP
QSPTFPESGHTSLYDEDKVPRDEPIHILNVAIKTDGDIEDDRLAAMFREFTQQNKATLVE
HGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQL
ELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEY
LQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGS
RLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAY
GDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAF
LPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDIIVIG
NDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDP
EDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSG
MIAGESSLAYDEVITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGRE
VYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDR
IIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGI
PVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLM
VFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTIN
PRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPTER
KELESKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRR
LLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEE
DGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTM
DSPST
NT seq
7038 nt
NT seq
+upstream
nt +downstream
nt
atggatgaaccatctccgttggccaaaactctggagctaaaccagcactcccgattcata
attgggtctgtgtctgaagacaactcagaagatgagatcagtaacctggtgaagctggac
ctagaagagaaggagggctccctgtcaccagcctccgtcagctcagatacactttctgat
ttggggatctctggcttacaggatggtttggcctttcacatgagatccagcatgtctggc
ttgcacctagtaaaacaaggtcgagacagaaagaaaatagactcacaacgagatttcact
gtggcttctccagcagaatttgttactcgttttgggggaaataaagtaattgagaaggtt
cttatcgccaacaatggtattgcagcagtgaaatgcatgcgatctatccgtcggtggtct
tatgaaatgtttcgaaatgaacgtgcaatccgatttgttgtcatggttacacctgaagac
cttaaagccaatgcagaatacattaagatggcagaccactatgttccagtgcctggagga
cccaacaacaacaattacgcaaatgtggagttgattcttgatattgctaaaaggatacct
gtacaagcagtgtgggctggctggggtcatgcctctgagaacccgaaactcccagaactg
ctcttaaaaaatggcattgctttcatgggccctccaagccaggccatgtgggctttgggg
gataagattgcatcttctattgtggctcaaactgcaggtatcccaactcttccctggagt
ggcagtggtcttcgagtggattggcaagaaaatgatttttcgaaacgtatcttaaatgtt
ccacaggatctgtatgagaaaggctatgtgaaggatgtggatgatggtctgaaggcagct
gaggaagttggctatccagtgatgatcaaggcctcagagggaggaggagggaaagggatc
agaaaagttaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaagtt
cctggatcacctatatttgtaatgagactagcaaaacaatctcgacatctggaggtccag
attctggcagatcagtatggcaatgctatttctttgtttggtcgtgactgctctgtgcag
cgcaggcatcagaagatcattgaagaagctcctgctgcgattgctaccccagcagtattt
gaacacatggaacagtgtgcagtgaaacttgccaaaatggttggttatgtgagtgctggg
actgtggaatacttgtacagccaggatggaagcttctactttttggaactgaaccctcgg
ctacaggttgaacatccttgtacagagatggtggctgatgtcaatcttcctgcagcacag
ctccagattgccatggggatccctctatttaggatcaaggatattcgtatgatgtatggg
gtatctccttggggagatgctcccattgattttgaaaattctgctcatgttccttgccca
aggggccacgtgattgctgctcggatcaccagtgaaaacccagatgaggggtttaagccc
agctctggaacagttcaggaacttaattttcgtagcaataagaacgtttggggttatttc
agtgttgctgctgctggaggacttcatgaatttgctgattctcagttcgggcactgcttt
tcctggggagaaaacagggaggaagcaatctcaaatatggtggtggcactgaaggagctg
tctattcggggtgactttcgaactacagtggaatacctcatcaaactgctggagacagaa
agctttcagcttaacagaatcgacactggctggctggacagactgatcgcagagaaagtg
caggcagagcgacctgacaccatgttgggagttgtgtgtggggctctccatgtagcagat
gtgagcctgaggaacagcatctctaacttccttcactccttagagaggggtcaagtcctt
cctgctcacacacttctgaacacagtagatgttgaacttatctatgaaggaatcaaatat
gtacttaaggtgactcggcagtctcccaactcctacgtagtgataatgaatggctcgtgt
gtggaagtggatgtgcatcggctgagtgatggtggcctgctcttgtcttatgacggcagc
agttacaccacatacatgaaggaagaggtggacagatatcgaatcacaattggcaataaa
acctgtgtgtttgagaaggaaaatgacccatctgtaatgcgctcaccgtctgctgggaag
ttaatccagtatattgtggaagatggcggacatgtgtttgctggccagtgctatgctgag
attgaggtaatgaagatggtgatgactttaacagctgtagaatctggctgcatccattat
gtcaaacgacctggagcagcacttgaccctggctgtgtgatagccaaaatgcaactggac
aaccccagtaaagttcaacaggctgagcttcacacgggcagtctaccacagatccagagc
acagctctcagaggcgagaagctccatcgagttttccactatgtcctggataacctggtc
aatgtgatgaatggatactgccttccagaccctttcttcagcagcagggtaaaagactgg
gtagaaagattgatgaagactctgagagacccctccttgcctctgctagagctgcaggat
atcatgaccagtgtctctggccggatccccctcaatgtggagaagtctattaagaaggaa
atggctcagtatgctagcaacatcacatcagtcctgtgtcagtttcccagccagcagatt
gccaacatcctagatagtcatgcagctacactgaaccggaaatctgagcgggaagtcttc
ttcatgaacacccagagcattgtccagctggtgcagaggtaccgaagtggcatccgtggc
cacatgaaggctgtggtgatggatctgctgcggcagtacctgcgagtagagacacagttt
cagaacggccactacgacaaatgtgtattcgcccttcgggaagagaacaaaagcgacatg
aacaccgtactgaactacatcttctcccacgctcaggtcaccaaaaagaatctcctggtg
acaatgcttattgatcagttatgtggccgggaccctacacttactgatgagctgctaaat
atcctcacagagctaacccaactcagcaagaccaccaacgctaaagtggcgctgcgcgct
cgtcaggttcttattgcttcccatttgccatcatatgagcttcgccataaccaagtagag
tctatcttcctatcagccattgacatgtatggacaccagttttgcattgagaacctgcag
aaactcatcctctcggaaacatctattttcgatgtcctcccaaactttttttaccacagc
aaccaggtggtgaggatggcagctctggaggtgtatgttcgaagggcttacattgcctat
gaactcaacagcgtacaacaccgccagcttaaggacaacacctgtgtggtggaatttcag
ttcatgctgcccacatcccatccaaacagagggaacatccccacgctaaacagaatgtcc
tttgcctccaacctcaaccactatggcatgactcatgtagctagtgtcagcgatgttctg
ttggacaacgccttcacgccaccttgtcagcggatgggcggaatggtctctttccggacc
tttgaagattttgtcaggatctttgatgaaataatgggctgcttctgtgactccccaccc
caaagccccacattcccagagtctggtcatacttcgctctatgatgaagacaaggtcccc
agggatgaaccaatacatattctgaatgtggctatcaagactgatggcgatattgaggat
gacaggcttgcagctatgttcagagagttcacccagcagaataaagctactttggttgag
catggcatccggcgacttacgttcctagttgcacaaaaggatttcagaaaacaagtcaac
tgtgaggtggatcagagatttcatagagaattccccaaatttttcacattccgagcaagg
gataagtttgaggaggaccgcatttatcgacacctggagcctgctctggctttccagtta
gagttgaaccggatgagaaattttgaccttactgccatcccatgtgctaatcacaagatg
cacctgtaccttggggctgctaaggtggaagtaggcacagaagtgactgactacaggttc
tttgttcgtgcgatcatcaggcactctgatctggtcacaaaggaagcttctttcgaatat
ctacaaaatgaaggggaacgactgctcctggaagctatggatgaattggaagttgctttt
aataatacaaatgtccgcactgactgtaaccacatcttcctcaactttgtgcccacggtc
atcatggacccatcaaagattgaagaatctgtgcggagcatggtaatgcgctatggaagt
cggctatggaaattgcgggtcctccaggcagaactgaaaatcaacattcgcctgacaaca
actggaaaagcaattcccatccgcctcttcctgacaaacgagtctggctactacttggac
atcagcctgtataaggaagtgactgactccaggacagcacagatcatgtttcaggcatat
ggagacaagcagggaccactgcatggaatgttaattaatactccatatgtgaccaaagac
cttcttcaatcaaagaggttccaggcacagtccttaggaacaacatatatatatgatatc
ccagagatgtttcggcagtcactcatcaaactctgggagtccatgtccacccaagcattt
cttccttcgcctcctttgccttccgacatcctgacgtatactgaactggtgttggatgat
caaggccagctggtccatatgaacagacttccaggaggaaatgagattggcatggtagcc
tggaaaatgagccttaaaagccctgaatatccagatggccgagatatcattgtcatcggc
aatgacattacatatcggatcggttcctttgggcctcaggaggatttgctgtttctcaga
gcttctgaacttgccagagcagaaggcatcccacgcatctacgtggcagcgaacagtgga
gctagaattggacttgcagaagaaatacgccatatgttccatgtggcctgggtagatcct
gaagatccctacaagggatacaagtatttatatctgacaccccaggattataagagagtc
agtgccctcaattctgtccactgtgaacatgtggaggatgaaggggaatccaggtacaag
ataacagatattatcgggaaagaagaaggacttggagcagagaaccttcggggttctgga
atgattgctggggaatcctcattggcttacgatgaggtcatcaccatcagcctggttaca
tgccgggccattggtattggggcttaccttgtccggctgggacaaagaaccatccaggtt
gagaattctcacttaattctgacaggagcaggtgccctcaacaaagtccttggtcgggaa
gtatacacctccaacaaccagcttgggggcatccagattatgcacaacaatggggttacc
cactccactgtttgtgatgactttgagggagtcttcacagtcttacactggctgtcatac
atgccgaagagcgtacacagttcagttcctctcctgaattccaaggatcctatagataga
atcatcgagtttgttcccacaaaggccccatatgatcctcggtggatgctagcaggccgt
cctcacccaacccagaaaggccaatggttgagtgggttttttgactatggatctttctca
gaaatcatgcagccctgggcacagaccgtggtagttggcagagccaggttagggggaata
cccgtgggagtagttgctgtagaaacccgaacagtggaactcagtatcccagctgatcct
gcgaacctggattctgaagccaagataatccagcaggccggccaggtttggttcccagac
tctgcatttaagacctatcaagctatcaaggactttaaccgtgaagggctacctctaatg
gtctttgccaactggagaggtttctctggtgggatgaaagatatgtatgaccaagtgctc
aagtttggcgcttacattgtggatggcttgcgggaatgttcccagcctgtaatggtttac
atcccgccccaggctgagcttcggggtggttcttgggttgtgatcgaccccaccatcaac
cctcggcacatggagatgtacgctgaccgagaaagcaggggatctgttctggagccagaa
gggacagtagaaatcaaattccgtaaaaaggatctggtgaaaaccatgcgtcgggtagat
ccagtttacatccgcttggctgagcgattgggcaccccagagctaagccccactgagcgg
aaggagctggagagcaagttgaaggagcgggaggagttcctaattcccatttaccatcag
gtagctgtgcagtttgctgacttgcacgacacaccaggccggatgcaggagaagggtgtc
attaacgatatcttggattggaaaacatcccgcaccttcttctactggaggctgaggcgc
ctcctgctggaggacctggtcaagaagaaaatccacaatgccaaccctgagctgactgac
ggccagatccaggccatgttgagacgctggtttgtagaagttgaaggcacagtgaaggct
tacgtctgggacaataataaggacctggtggagtggctggagaagcaactgacagaggaa
gatggcgtccgctctgtgatagaggagaacatcaaatacatcagcagggactatgtcctg
aagcagatccgcagcttggtccaggccaacccagaagtcgccatggactccatcgtccac
atgacccagcacatctcacccacccagcgagcagaagttgtaaggatcctctccactatg
gattccccttccacgtag
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integrated database retrieval system
