Mus musculus (house mouse): 107589
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Entry
107589 CDS
T01002
Symbol
Mylk, 9530072E15Rik, A930019C19Rik, KRP, MLCK108, MLCK210, Mlck, nmMlck, smMLCK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform 1
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04020
Calcium signaling pathway
mmu04022
cGMP-PKG signaling pathway
mmu04270
Vascular smooth muscle contraction
mmu04371
Apelin signaling pathway
mmu04510
Focal adhesion
mmu04517
IgSF CAM signaling
mmu04611
Platelet activation
mmu04810
Regulation of actin cytoskeleton
mmu04921
Oxytocin signaling pathway
mmu04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
107589 (Mylk)
04020 Calcium signaling pathway
107589 (Mylk)
04022 cGMP-PKG signaling pathway
107589 (Mylk)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
107589 (Mylk)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
107589 (Mylk)
09142 Cell motility
04810 Regulation of actin cytoskeleton
107589 (Mylk)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
107589 (Mylk)
09152 Endocrine system
04921 Oxytocin signaling pathway
107589 (Mylk)
09153 Circulatory system
04270 Vascular smooth muscle contraction
107589 (Mylk)
09154 Digestive system
04971 Gastric acid secretion
107589 (Mylk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
107589 (Mylk)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
107589 (Mylk)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: CAMK group
MLCK family
107589 (Mylk)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
Ig_VEGFR-1-like_5th
C2-set_2
Ig_MYOM1
fn3
VEGFR1-3_N_Ig-like
Ig_C17orf99
FN3_DSCAM-DSCAML_C
Ig_SEMA-3_4_7A
Fn3_PBP1
Kinase-like
Ig_Rha78A_N
Kdo
DUF5898
AvrM_N
Ig_J_second
Motif
Other DBs
NCBI-GeneID:
107589
NCBI-ProteinID:
NP_001395190
MGI:
894806
Ensembl:
ENSMUSG00000022836
LinkDB
All DBs
Position
16:34565569..34822806
Genome browser
AA seq
1941 aa
AA seq
DB search
MGDVKLFASSHMSKTSHSVDPSKVSSMPLTEAPAFILPPRNLCVKEGATAKFEGRVRGYP
EPQVTWHRKGQAITNGGRFLLDCGVRGTFSLVIHTVREEDKGKYTCEASNGSGARQVTVE
LTVEGNSMKKRDQPVLSKASGFPGETRPSIWGECPPKFATKLGRAVVKEGQMGRFSCKIT
GRPPPQVTWLKGNVPLQPSARVSMSEKNGMQILEIRGVTRDDLGVYTCMVVNGSGKASMS
AELSIPGLDNAARLAVRGTKAPSPDIRKEVTNGVSKDPETVAESKNCPSPQRSGSSARAT
NSHLKSPQEPKPKLCEDAPRKVPQSSILQKSTSTITLQALKVQPEARVPAIGSFSPGEDR
KSLAAPQQATLPTRQSSLGGSVGNKFVTGNIPRESQRESTFPRFESQPQSQEVTEGQTVK
FICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLCLLRARTRDSGRYSCTASNS
LGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQ
PIQFAHSICEAGVAELHIQDALPEDRGTYTCLAENAMGQVSCSATVTVQEKKGEGEREHR
LSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFHFE
QKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRTRAVLTVQEPHDGTQPWFISKPRSVTA
TLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGHFELLQNEDVFTLVLKNVQPWHAGQY
EILLKNRVGECSCQVSLMLHNSPSRAPPRGREPASCEGLCGGGGVGAHGDGDRHGTLRPC
WPARGQGWPEEEDGEDVRGLLKRRVETRLHTEEAIRQQEVGQLDFRDLLGKKVSTKTVSE
DDLKDIPAEQMDFRANLQRQVKPKTISEEERKVHSPQQVDFRSVLAKKGTPKTPVPEKAP
PKAATPDFRSVLGGKKKSPSENGGNSAEVLNVKAGESPTPAGDAQAIGALKPVGNAKPAE
TPKPIGNAKPTETLKPVGNTKPAETLKPIANAQPSGSLKPVTNAQPAEPQKPVGNAKSAE
TSKPAGKEEVKEVKNDVNCKKGQVGATGNEKRPESQGSAPVFKEKLQDVHVAEGEKLLLQ
CQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSIEKALPEDRGLYKCVAKNSAGQ
AECSCQVTVDDAQTSENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPTKAAMPP
QIIQFPEDQKVRAGEPVELFGKVAGTQPITCKWMKFRKQIQESEHIKVENGESGSKLTIL
AARQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYD
GGSAVQSYNVEIWDTEDKVWKELATCRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQE
SELTAVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTVNTEQKVSDVYDIEERLGSGKFGQV
FRLVEKKTGKIWAGKFFKAYSAKEKDNIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVL
EIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTG
TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGL
SPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPW
LMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPT
SPINAEKLESEDDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP
EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI
VETMEEGEGEEGGEEEEEEEE
NT seq
5826 nt
NT seq
+upstream
nt +downstream
nt
atgggggacgtgaaactgtttgcctcgtcacacatgtctaaaacctcccacagtgtggat
ccctcgaaggtcagctccatgcctctcaccgaggccccagctttcattctgccccctcgg
aacctctgcgtcaaagaaggagccacagccaagttcgaagggagggtccggggctaccca
gagccccaggtgacatggcacagaaaagggcaagccatcaccaatggtggccgcttcctg
ctggactgtggagtgcgggggacttttagtcttgtcatccacactgtccgcgaggaggac
aagggcaaatacacctgtgaagctagcaatggcagtggcgcccgccaggtgaccgtggag
ctgactgtggaagggaattctatgaagaagcgtgatcagcctgttctttctaaagcctca
ggatttccaggggagactcgtcctagcatctggggtgagtgcccaccaaagtttgccacc
aagctgggcagagctgtggtcaaagaagggcagatggggcgattctcctgcaagatcact
ggccggcctccaccacaggtcacctggctcaagggaaatgtcccgttgcagccaagtgcc
cgtgtgtcaatgtcagagaagaatggcatgcagatcctggagatccgtggggtcactcgg
gatgacctgggcgtgtacacctgcatggtggtgaatgggtcagggaaagcctccatgtcg
gcggagctctccatcccaggtttggacaatgccgctaggttggctgtgagaggaaccaaa
gcccccagtccagacatcaggaaggaggtgaccaatggagtctccaaagacccagagact
gtggctgaaagtaagaactgtccaagtccccagaggagtggctcctcagcccgggccacc
aacagtcacctcaagtccccgcaggagcccaagccaaagctgtgtgaggatgctcccaga
aaggtcccgcagtcctccatcctgcagaagtccaccagcaccatcactctgcaggccttg
aaagtccagccagaagcgagagtaccagccatagggtccttctctcctggggaagacagg
aagagtctggctgcccctcagcaagccacactccctaccagacagtctagcctgggaggt
tccgttgggaacaagtttgttaccgggaacatccccagagagagccaaagggagtcaaca
ttccccagatttgagagtcagccccaaagccaggaagtcactgaaggtcagacagtcaag
ttcatctgcgaggtttcaggtataccaaagcctgacgtgggctggttcctggaaggcatc
cccgtgaggagacgggaaggcatcactgaggtttatgaagatggtgtatcccatcacctg
tgcctgctgagagcccggacgagagacagtgggaggtacagctgcacagcatccaatagc
cttggccaggtgtcctgcagctggagcctgctggtggaccggccgaacttggcacagaca
gccccttcattctctagtgttctgaaggacagtgttgtcattgagggccaggattttgtg
ctacggtgctcagtgcaggggactccagcaccccgggtcacgtggctgctcaatggacag
cccatccagtttgctcactccatctgtgaggcaggcgtggctgagctccacatccaggat
gccctgccagaggaccgtggcacctacacctgcctggctgagaatgccatggggcaggtg
tcctgcagcgccactgtcaccgtccaagagaagaaaggtgaaggagagagggaacaccgt
ctgtccccagctcgcagcaagcccatcgcacccatcttcctgcagggcctctccgacctc
aaagtcatggatggaagccaggtcactatgacagtccaggtgtcagggaacccacctccg
gaagtcatctggcttcacgacgggaatgagattcaggagtccgaggacttccacttcgag
cagaagggtggctggcacagcctgtgtatccaggaggtgttcccggaggacacgggcacg
tacacctgtgaggcctggaacagtgccggggaggtccgcacccgggccgtcctcaccgtg
caagagcctcatgatggcacccagccctggttcatcagcaagcctcgttcggtgacagcc
accctgggccagagtgtcctcatctcctgcgccatagctggagacccctttcccaccgtg
cactggctccgggatggcagagccctctccaaggacagtggccactttgagctgctccag
aatgaggacgtgttcaccctggttctaaagaacgtgcagccctggcatgccggccagtat
gagattctgctcaagaaccgggttggcgagtgtagttgccaagtgtcactgatgcttcac
aacagcccttccagagccccaccacgggggcgggagcctgccagctgcgagggcctctgt
ggtggtggaggagttggtgctcatggtgatggtgaccgtcatgggaccctgaggccctgc
tggccagcaagagggcaaggttggcctgaggaggaagacggagaagacgtgagggggctg
ttgaagagacgggtggagaccaggctgcacacagaagaggccatccgccagcaggaggtg
gggcagctggattttcgagacctcctgggaaagaaggtgagcaccaagaccgtctcagaa
gacgacctgaaggacatcccagccgagcagatggatttccgcgccaaccttcagcggcaa
gtgaagccaaagaccatatccgaggaagagaggaaggtgcatagccctcagcaggttgac
ttccggtctgtcctcgccaagaaggggacccctaagacccccgttcctgagaaggcacct
ccaaaagctgccaccccagactttcgctctgtgctaggtggcaagaagaagtcaccctcg
gagaatgggggcaacagcgctgaggtcttgaatgtcaaggctggggaaagccccacacct
gcaggcgatgcgcaggccatcggggccctgaaacccgtaggcaatgccaagcctgctgag
accccgaaacctataggtaatgccaagcctaccgagaccctgaagcctgtgggcaacacc
aagcctgccgagaccctgaaacccatagccaacgcacagccttcagggtccctgaaacct
gtaaccaacgcacaacctgctgagccccagaagcctgtgggcaatgccaagtctgctgag
acctcgaaaccagctgggaaagaagaagtcaaggaggtaaagaatgatgtgaactgtaag
aaagggcaggtcggagccacgggcaatgaaaagcgacccgagagccaaggctcggcccca
gttttcaaggaaaagctacaagatgtccatgtggcagagggggagaagctgctactccaa
tgccaggtgatctctgatccccccgccactgtcacctggtcgctgaatgggaagacactc
aagaccacaaaattcatcgtcctcgcccaagaaggctcacgtttctctgtctccatcgag
aaggcactgcctgaggaccgaggtttgtacaagtgtgtagccaagaacagcgctggccag
gcagagtgttcctgccaagtcactgtggacgatgctcagaccagtgagaacaccaaggcc
ccggagatgaaatcccggagacccaagagctctcttccccctgtgctaggaacagagagc
gacgcaactgtgaaaaagaaacctgcccccaagacacccacaaaagcagctatgccccct
caaatcatccagttccccgaggaccagaaggtgcgcgcaggagaacctgtggagctgttt
gggaaagtggctggcacccagcccatcacctgcaagtggatgaagttccgaaagcagatc
caggagagcgagcatatcaaggtggagaatggcgagagcggcagcaagctcaccatcctg
gccgcgcggcaggagcactgtggctgctacacactggtggtggagaacaagctgggcagc
aggcaggcccaagtcaacctcacggtcgtggataagccagaccccccggctggcacacct
tgtgcttctgacattcggagttcctcactgaccctgtcctggtatggctcctcatatgat
gggggcagtgctgtacagtcctacaatgtggagatctgggacacagaggacaaggtgtgg
aaagagctagccacgtgccgcagcacctcttttaatgtccaagacctgctgcctgaccgc
gagtacaaattccgagtgcgtgcagtcaacgtctatggaaccagcgagccaagccaagag
tccgagctcacagctgtgggagagaaacctgaagagccaaaggatgaagtggaagtgtcc
gatgatgacgaaaaggaacctgaggttgattaccggacggtgactgttaacactgaacag
aaagtgtctgatgtgtatgacattgaagagcgactaggatctgggaagtttggacaagtc
ttccgacttgtggaaaagaaaactggaaaaatctgggcagggaaatttttcaaggcctat
tccgccaaggagaaagacaacatccgtcaggagatcagcatcatgaactgcctccaccac
cccaagctggtccagtgtgtggatgccttcgaagaaaaggccaacattgtcatggttctg
gagatcgtgtccgggggtgagctgtttgagcgtatcattgacgaggacttcgagctgacg
gagcgggagtgtatcaagtacatgaggcagatctcggaaggggtggagtacatccacaag
cagggcattgtgcacctggacctcaagcccgagaacatcatgtgtgtcaacaagacaggc
accaggatcaagctcattgacttcggcctggcacggagactcgagaacgctgggtctctg
aaggtcctctttgggaccccagagtttgtggctcctgaagtgatcaactatgagcccatc
ggctacgccacagacatgtggagcatcggggtcatctgctatattctggtcagcggactt
tctcccttcatgggtgacaatgataacgagaccttagccaacgtcacttcagccacctgg
gacttcgatgacgaggcattcgatgagatctccgatgacgcaaaggatttcatcagtaac
ttgctgaagaaagatatgaaaaaccgtctggactgcacccagtgccttcagcacccatgg
ctgatgaaagacaccaagaacatggaggccaagaagctgtccaaggaccggatgaagaaa
tacatggcaagaaggaagtggcagaaaacgggcaatgctgtgagagccatcgggagactg
tcctctatggcaatgatctcagggctcagtggcaggaaatcttcaacagggtcaccaacc
agcccaatcaatgcggagaaactagagtctgaagacgatgtctcccaagctttcctggag
gctgttgctgaggaaaagccccatgtgaaaccttatttctctaagaccatccgtgatctg
gaagtcgtggagggaagcgctgctagatttgactgcaagattgaaggatacccagaccct
gaggtggtctggttcaaggatgaccaatcaatcagggagtcccgccacttccagatagac
tacgacgaagacggcaactgctcgctcatcatcagcgacgtctgtggggatgatgacgcc
aagtacacctgcaaggctgtcaacagcctcggagaagccacctgcactgcggagctcatc
gtggagaccatggaggaaggggaaggggaggaggggggagaggaggaggaggaggaggag
gagtga
DBGET
integrated database retrieval system
