Mus musculus (house mouse): 110355
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Entry
110355 CDS
T01002
Symbol
Grk2, Adrbk-1, Adrbk1, Bark-1, beta_ARK, betaARK1
Name
(RefSeq) G protein-coupled receptor kinase 2
KO
K00910
beta-adrenergic-receptor kinase [EC:
2.7.11.15
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04062
Chemokine signaling pathway
mmu04144
Endocytosis
mmu04340
Hedgehog signaling pathway
mmu04724
Glutamatergic synapse
mmu04740
Olfactory transduction
mmu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
110355 (Grk2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110355 (Grk2)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
110355 (Grk2)
09156 Nervous system
04724 Glutamatergic synapse
110355 (Grk2)
09157 Sensory system
04740 Olfactory transduction
110355 (Grk2)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110355 (Grk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
110355 (Grk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
110355 (Grk2)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.15 beta-adrenergic-receptor kinase
110355 (Grk2)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
110355 (Grk2)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
110355 (Grk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
PH
Kinase-like
DUF5647
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
110355
NCBI-ProteinID:
NP_001277747
MGI:
87940
Ensembl:
ENSMUSG00000024858
UniProt:
Q99MK8
Q3U1V3
LinkDB
All DBs
Position
19:complement(4336029..4356356)
Genome browser
AA seq
689 aa
AA seq
DB search
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLNHLEEAKPLVEFYEEIKKYEKLETEEERVVRSREIFDSYIMKELLAC
SHPFSKNATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKRPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
KAKNKQLGHEEDYALGKDCIVHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
LTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQR
VPKMKNKPRSPVVELSKVPLIQRGSANGL
NT seq
2070 nt
NT seq
+upstream
nt +downstream
nt
atggccgacctggaggcggtgctggccgatgtgagctacctgatggccatggagaagagc
aaggccacgccggccgcgcgcgccagcaagaagatcctgctgccagagcccagcatccgc
agcgtcatgcagaagtatctggaggaccgaggagaagtgacctttgaaaagatcttttcg
cagaagttagggtacctgcttttccgggacttctgcctgaaccatctggaagaggccaag
cccttggtggagttctacgaagagatcaagaaatatgagaagctggagacagaggaggaa
cgtgtggtccgcagccgagagatctttgactcctatattatgaaagaactgctggcctgc
tcacatcccttttcaaagaatgctacggagcatgtccagggccacctggtgaagaagcag
gtgcctccagatctcttccagccatacattgaggagatttgtcagaacctccgaggggac
gtgttccagaagttcatagagagtgacaagttcacacggttctgccagtggaagaatgtt
gagctcaacatccacctgaccatgaatgacttcagtgtgcatcgaatcatcgggcgtggg
ggcttcggtgaggtctatgggtgccggaaagcagacacaggcaagatgtacgccatgaag
tgtctggacaagaaacgcatcaagatgaagcagggagagaccctggctctgaacgagcgg
atcatgctttccctcgtcagcaccggggactgccccttcatcgtgtgcatgtcatatgca
ttccacacaccagacaagctcagcttcatcctggacctcatgaacggtggggacctgcac
taccacctgtctcagcatggagtcttctctgaagccgacatgcgcttctacgccgctgag
atcatcctgggccttgaacacatgcacaatcgctttgtagtctacagggacctgaagcca
gccaacattctcctggatgaacatggccatgtgagaatctcggacctgggcctagcctgt
gacttctccaagaagaggcctcatgccagtgtgggcacacacgggtacatggcccccgaa
gtcctacagaagggcgtggcctatgacagcagtgcagactggttctccctgggctgcatg
ctcttcaagttgttgcggggacacagccccttccggcagcacaagaccaaagacaagcat
gagattgaccgcatgacgttgacgatggctgtagagctgcctgactccttctcccctgaa
ctccgatccctgctggaaggtttgttgcagagggacgtcaatcggagactaggctgtctg
ggccgtggggctcaggaggtaaaagaaagtcctttctttcgttccctggactggcagatg
gtcttcttacagaagtaccctcctccactgatccccccacgtggggaggtgaatgcagct
gacgctttcgacattggctcctttgatgaggaggacacaaaaggaatcaagttactggac
agtgaccaggaactgtaccgcaacttccctctcaccatctctgagcggtggcaacaggag
gtggcagagactgtctttgataccatcaatgctgaaacagaccggctggaggcacgaaag
aaggccaaaaacaaacagctgggccacgaggaggactatgccctgggtaaggactgcatc
gtgcatggctacatgtccaagatgggcaaccccttcctgacccagtggcagcggcgatac
ttctacttgttccccaaccggctcgagtggaggggtgaaggcgaggctccgcagagcctc
ctgaccatggaggagatccagtcagtggaagagacacagatcaaggaacgcaagtgtctc
ctgcttaagatccgaggtggcaagcagtttgtcctgcagtgtgatagtgatccagagctg
gtgcaatggaaaaaggagctgcgtgatgcctaccgcgaggcccagcagctggtacagcga
gtacccaagatgaagaacaagccacgctcgcctgtggtggagctgagcaaggtgccgctg
atccagcgtggcagtgccaacggcctctga
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integrated database retrieval system
