Mus musculus (house mouse): 11350
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Entry
11350 CDS
T01002
Symbol
Abl1, Abl, E430008G22Rik, c-Abl
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform b
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04012
ErbB signaling pathway
mmu04014
Ras signaling pathway
mmu04110
Cell cycle
mmu04360
Axon guidance
mmu04517
IgSF CAM signaling
mmu04722
Neurotrophin signaling pathway
mmu05200
Pathways in cancer
mmu05206
MicroRNAs in cancer
mmu05208
Chemical carcinogenesis - reactive oxygen species
mmu05220
Chronic myeloid leukemia
mmu05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
11350 (Abl1)
04014 Ras signaling pathway
11350 (Abl1)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
11350 (Abl1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
11350 (Abl1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
11350 (Abl1)
09158 Development and regeneration
04360 Axon guidance
11350 (Abl1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
11350 (Abl1)
05206 MicroRNAs in cancer
11350 (Abl1)
05208 Chemical carcinogenesis - reactive oxygen species
11350 (Abl1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
11350 (Abl1)
09166 Cardiovascular disease
05416 Viral myocarditis
11350 (Abl1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
11350 (Abl1)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
11350 (Abl1)
Protein kinases [BR:
mmu01001
]
Non-receptor tyrosine kinases
ABL family
11350 (Abl1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
ABC1
SH3_6
Motif
Other DBs
NCBI-GeneID:
11350
NCBI-ProteinID:
NP_033724
MGI:
87859
Ensembl:
ENSMUSG00000026842
UniProt:
P00520
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:31578256..31697105
Genome browser
AA seq
1123 aa
AA seq
DB search
MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSE
NDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVN
SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS
DGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTIYGVSPNYDKWEMERT
DITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQ
LLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFI
HRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKS
DVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNP
SDRPSFAEIHQAFETMFQESSISDEVEKELGKRGTRGGAGSMLQAPELPTKTRTCRRAAE
QKDAPDTPELLHTKGLGESDALDSEPAVSPLLPRKERGPPDGSLNEDERLLPRDRKTNLF
SALIKKKKKMAPTPPKRSSSFREMDGQPDRRGASEDDSRELCNGPPALTSDAAEPTKSPK
ASNGAGVPNGAFREPGNSGFRSPHMWKKSSTLTGSRLAAAEEESGMSSSKRFLRSCSASC
MPHGARDTEWRSVTLPRDLPSAGKQFDSSTFGGHKSEKPALPRKRTSESRSEQVAKSTAM
PPPRLVKKNEEAAEEGFKDTESSPGSSPPSLTPKLLRRQVTASPSSGLSHKEEATKGSAS
GMGTPATAEPAPPSNKVGLSKASSEEMRVRRHKHSSESPGRDKGRLAKLKPAPPPPPACT
GKAGKPAQSPSQEAGEAGGPTKTKCTSLAMDAVNTDPTKAGPPGEGLRKPVPPSVPKPQS
TAKPPGTPTSPVSTPSTAPAPSPLAGDQQPSSAAFIPLISTRVSLRKTRQPPERIASGTI
TKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAI
NKLESNLRELQICPATASSGPAATQDFSKLLSSVKEISDIVRR
NT seq
3372 nt
NT seq
+upstream
nt +downstream
nt
atgttggagatctgtttgaagttggtgggctgcaaatccaagaaggggctctcttcgtcc
tccagctgctacctggaagaagccctgcagaggccagtggcatctgactttgagccccag
ggtctcagcgaagcagctcgatggaactccaaggaaaaccttcttgctgggcccagtgaa
aatgaccccaacctttttgtggcactctatgattttgtggccagtggagataacactctc
agcatcactaaaggtgaaaagctccgggtcttgggttataatcacaatggggaatggtgt
gaagcccaaacgaaaaatggccaaggatgggtcccaagcaactacatcacccccgtcaac
agcctggagaaacattcctggtatcatggccctgtatctcggaatgctgctgagtatctg
ctgagcagcggaatcaacggcagcttcttagtgcgggagagtgagagtagccctggccag
agatccatctcgctgcggtatgaagggagggtgtaccactacaggatcaacactgcctct
gatggcaagctgtacgtgtcctccgagagccgcttcaacactctggctgagttagttcac
catcactccacggtggctgatggcctcatcaccacactccactacccagctcccaagcgc
aacaagcccactatctacggtgtgtcccccaactacgacaagtgggaaatggagcgcacc
gacatcaccatgaagcacaagttgggtggaggccagtacggggaggtgtacgagggcgtt
tggaagaagtacagcctcactgtggccgtgaagaccttgaaggaggacaccatggaggtg
gaggagttcctgaaggaagcggcggtgatgaaggagatcaaacaccctaacctggtgcag
ctgctaggggtgtgtacccgggaaccaccattctacataatcactgagttcatgacctat
gggaacctgctggactacctgagggagtgtaaccggcaggaggtgagcgccgtggtactg
ctctacatggccacacagatctcatcagccatggagtacttggagaagaagaacttcatc
cacagagaccttgctgcccggaactgcctggtaggggaaaaccacttggtgaaggtggct
gattttggcctgagcaggttgatgacaggggacacctacacggcccatgctggagccaaa
ttccccatcaaatggaccgcacctgagagcctggcctacaacaagttctccatcaagtcg
gacgtgtgggcatttggagtattgctctgggagattgctacctatggcatgtcaccttac
ccgggaattgacctgtctcaggtttatgagctgctggaaaaagactaccgcatggagcgc
cctgaaggctgcccggagaaggtctacgagctcatgcgagcatgttggcagtggaacccc
tctgaccggccctcctttgctgaaatccaccaagcctttgaaaccatgttccaggaatcc
agtatctcagatgaggtggagaaggagctggggaaacgaggcacgagaggaggtgctggg
agtatgctgcaggccccagagctgcccaccaagaccagaacctgcaggagagcagctgag
cagaaagatgcgcctgacacccctgagctgctccacacgaagggcctgggagaaagcgat
gcactggacagtgagcctgctgtatcgccactgcttcctcggaaagagcgcgggccccca
gacggcagcctaaatgaagatgagcgccttctccccagagacagaaagaccaacctgttc
agcgctttgatcaagaagaagaagaaaatggcgccgacgccccctaagcgcagcagttcc
ttccgagagatggatggccagccagaccgcagaggggctagtgaggatgacagcagggaa
ctctgcaatggaccaccagctctcacctcagacgcagcagagcctaccaagtccccaaag
gccagcaatggggctggcgtccctaatggagccttccgggagccgggcaactcaggcttc
cgttctccccacatgtggaaaaagtccagcacactgaccgggagccgcctggctgctgcc
gaagaggagagcggcatgagctccagtaagcgcttcctgcgttcttgttcggcctcctgc
atgccccatggggcaagggacacagagtggcggtcggtcacgctgcctcgagacctgccg
tctgctggcaagcagtttgactcatccacctttggagggcacaaaagcgaaaagccagct
ctgcctcggaaacgcaccagtgagagcaggtctgagcaggtggccaaaagcacggcgatg
ccccctccccggctggtgaagaagaacgaggaggctgctgaagaaggcttcaaagacaca
gaatccagccctggctccagccctcccagcttgactcccaaactcctccgcaggcaggtc
actgcctctccttcctctggcctctctcacaaggaagaggccaccaagggcagtgcctca
ggcatggggactccggccactgcagagccagcaccccccagcaacaaagtgggcctcagc
aaggcctcctctgaggagatgcgcgtaaggaggcacaagcacagctcggagtccccaggg
agagacaaggggcgactggctaagctcaagcctgccccgccgcctcctcctgcctgcaca
ggaaaagcaggcaagcccgcacagagccccagccaagaggccggggaggcaggggggccc
acaaagacaaaatgcacgagtctggctatggatgctgtgaacactgaccccaccaaggcc
ggcccacctggagaaggactgagaaagcctgtgcccccatctgtgccaaagccccagtcg
acggctaagcctccagggactcccaccagcccggtctccaccccctccacagcaccagct
ccttcacccctggctggggaccagcagccatcttctgccgccttcatccccctcatatca
acccgtgtgtctcttaggaagacccgccagccgccagagcgcattgccagtggcaccatc
accaagggtgtggttctggacagtactgaggccctgtgccttgccatctcccggaactca
gagcagatggccagccacagtgctgtactggaggctggcaagaacctgtacactttctgt
gtgagctatgtggactctatccagcagatgaggaacaagtttgccttccgtgaggctatc
aacaagctggagagcaacctccgagagctgcagatctgccctgccacagcctccagtggg
ccagctgccacccaagacttcagcaagctgctcagctctgtgaaggagatcagcgacatt
gtccggaggtag
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integrated database retrieval system
