Mus musculus (house mouse): 11480
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Entry
11480 CDS
T01002
Symbol
Acvr2a, ActrIIa, Acvr2, TactrII
Name
(RefSeq) activin receptor IIA
KO
K04670
activin receptor type-2A [EC:
2.7.11.30
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04060
Cytokine-cytokine receptor interaction
mmu04350
TGF-beta signaling pathway
mmu04550
Signaling pathways regulating pluripotency of stem cells
mmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
11480 (Acvr2a)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
11480 (Acvr2a)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
11480 (Acvr2a)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
11480 (Acvr2a)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
11480 (Acvr2a)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
11480 (Acvr2a)
Protein kinases [BR:
mmu01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
11480 (Acvr2a)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Activin_recp
Motif
Other DBs
NCBI-GeneID:
11480
NCBI-ProteinID:
NP_031422
MGI:
102806
Ensembl:
ENSMUSG00000052155
UniProt:
P27038
Q8BRV4
A2AI38
Structure
PDB
PDBj
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All DBs
Position
2:48704121..48793276
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AA seq
513 aa
AA seq
DB search
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHC
FATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEM
EVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGP
PPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPG
MKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGL
AYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQV
GTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIG
QHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERIT
QMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgggagctgctgcaaagttggcgttcgccgtctttcttatctcttgctcttcaggtgct
atacttggcagatcagaaactcaggagtgtcttttctttaatgctaattgggaaagagac
agaaccaaccagactggtgttgaaccttgctatggtgataaagataaacggcgacattgt
tttgctacctggaagaatatttctggttccattgaaatagtgaagcaaggttgttggctg
gatgatatcaactgctatgacaggactgattgtatagaaaaaaaagacagccctgaagtg
tacttttgttgctgtgagggcaatatgtgtaatgaaaagttctcttattttccggagatg
gaagtcacacagcccacttcaaatcctgttacaccgaagccaccctattacaacattctg
ctgtattccttggtaccactaatgttaattgcaggaattgtcatttgtgcattttgggtg
tacagacatcacaagatggcctaccctcctgtacttgttcctactcaagacccaggacca
cccccaccttccccattactagggttgaagccattgcagctgttagaagtgaaagcaagg
ggaagatttggttgtgtctggaaagcccagttgctcaatgaatatgtggctgtcaaaata
tttccaatacaggacaaacagtcctggcagaatgaatatgaagtctatagtctacctgga
atgaagcatgagaacatactacagttcattggtgcagagaaaagaggcaccagtgtggat
gtggacctgtggctaatcacagcatttcatgaaaagggctcactgtcagactttcttaag
gctaatgtggtctcttggaatgaactttgtcatattgcagaaaccatggctagaggattg
gcatatttacatgaggatatacctggcttaaaagatggccacaagcctgcaatctctcac
agggacatcaaaagtaaaaatgtgctgttgaaaaacaatctgacagcttgcattgctgac
tttgggttggccttaaagttcgaggctggcaagtctgcaggtgacacccatgggcaggtt
ggtacccggaggtatatggctccagaggtgttggagggtgctataaacttccaaagggac
gcatttctgaggatagatatgtacgccatgggattagtcctatgggaattggcttctcgt
tgcactgctgcagatggacccgtagatgagtacatgttaccatttgaggaagaaattggc
cagcatccatctcttgaagatatgcaggaagttgttgtgcataaaaaaaagaggcctgtt
ttaagagattattggcagaaacatgcaggaatggcaatgctctgtgaaacgatagaagaa
tgttgggatcatgatgcagaagccaggttatcagctggatgtgtaggtgaaagaattact
cagatgcaaagactaacaaatatcattactacagaggacattgtaacagtggtcacaatg
gtgacaaatgttgactttcctcccaaagaatctagtctatga
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