Mus musculus (house mouse): 11481
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Entry
11481 CDS
T01002
Symbol
Acvr2b, 4930516B21Rik, AI047905, ActRIIB
Name
(RefSeq) activin receptor type-2B precursor
KO
K13596
activin receptor type-2B [EC:
2.7.11.30
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04060
Cytokine-cytokine receptor interaction
mmu04350
TGF-beta signaling pathway
mmu04550
Signaling pathways regulating pluripotency of stem cells
mmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
11481 (Acvr2b)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
11481 (Acvr2b)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
11481 (Acvr2b)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
11481 (Acvr2b)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
11481 (Acvr2b)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
11481 (Acvr2b)
Protein kinases [BR:
mmu01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
11481 (Acvr2b)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Activin_recp
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
11481
NCBI-ProteinID:
NP_031423
MGI:
87912
Ensembl:
ENSMUSG00000061393
UniProt:
P27040
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:119231081..119271214
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AA seq
536 aa
AA seq
DB search
MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCY
ASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEPG
GPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEVRQCQR
WAGRRDGCADSFKPLPFQDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAV
KIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDY
LKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAV
LADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL
VSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVT
IEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLLPKESSI
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
atgacggcgccctgggcggccctcgcccttctctggggatcgctgtgcgccggttccggg
cgaggggaggctgagactcgggagtgcatctactacaacgccaactgggagctggagcgc
accaaccagagcggcctggagcgctgcgagggggaacaggacaagcggctgcactgctac
gcctcgtggcgcaacagctcgggcaccatcgagctggtgaagaagggctgctggctagat
gacttcaattgctacgacaggcaggagtgtgtggccaccgaggagaacccccaggtgtac
ttctgctgctgcgaaggcaacttctgcaacgagcgcttcacccacttgccggagcctggg
ggcccagaagtcacgtacgagccacccccgacagcccccaccctgctcacggtgctggcc
tactcgctgctgcccattggaggcctctctctcatcgtcctgctggccttctggatgtat
cgtcatcggaagcctccctacggccatgtggacatccatgaggtgagacagtgccagcgt
tgggcagggagaagggacggctgtgcggactcctttaagcccttgcctttccaggacccg
gggcctccgcccccatcccctctggtgggcctgaagccactacagctgctggagatcaag
gctcggggccgctttggctgcgtttggaaagctcagctcatgaacgactttgtggctgtg
aagatcttcccacttcaggacaagcagtcgtggcagagtgaacgggaaatcttcagcaca
cccggcatgaagcacgaaaacttgttgcagttcattgctgccgagaaacgaggctccaac
ctggaggtggagctgtggctcatcacagccttccacgacaagggctccctcacggattac
ctcaaggggaacatcatcacgtggaacgaactgtgccacgtggcggagacgatgtcacga
ggcctctcatacctgcatgaggatgtgccgtggtgtcgtggtgagggccacaagccttct
attgcccacagggacttcaaaagcaagaatgtactgctgaagagcgacctcaccgcggtg
ctggctgacttcggcctggctgttcggtttgagccagggaagcctcctggggatacccat
ggacaggttggcaccagacggtacatggcccctgaggtgctggaaggagccatcaacttc
cagagagacgccttcctgcgtatcgacatgtacgccatgggcctggtgctgtgggagctc
gtctctcggtgcaaggctgcagacgggcctgtcgatgagtacatgctgcccttcgaggag
gagattggccagcacccttcgctggaggagcttcaggaggtggttgtccacaagaagatg
aggcccacgattaaggatcactggctgaaacacccgggcctggcccagctctgcgtgacc
atcgaggagtgctgggaccatgatgcagaggctcgcctttctgcaggctgtgtagaagag
cgggtatccctgatcaggaggtcggtcaacggcactacctcggactgtctcgtctctctg
gtgacctccgtcaccaatgtggacctgctccctaaagagtccagcatctaa
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