KEGG   Mus musculus (house mouse): 114875
Entry
114875            CDS       T01002                                 
Symbol
Plcz1, 1700041H07Rik, PLCzeta
Name
(RefSeq) phospholipase C, zeta 1
  KO
K05861  phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00562  Inositol phosphate metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04070  Phosphatidylinositol signaling system
mmu04114  Oocyte meiosis
mmu04919  Thyroid hormone signaling pathway
Module
mmu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    114875 (Plcz1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    114875 (Plcz1)
   04070 Phosphatidylinositol signaling system
    114875 (Plcz1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    114875 (Plcz1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    114875 (Plcz1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    114875 (Plcz1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     114875 (Plcz1)
Membrane trafficking [BR:mmu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    114875 (Plcz1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y EF-hand_like C2 EF-hand_7 EF-hand_6 EF-hand_1 EF-hand_15
Other DBs
NCBI-GeneID: 114875
NCBI-ProteinID: NP_473407
MGI: 2150308
Ensembl: ENSMUSG00000030230
UniProt: Q8K4D7
LinkDB
Position
6:complement(139933118..139987188)
AA seq 647 aa
MESQLHELAEARWFLSKVQDDFRGGKINVEITHKLLEKLDFPCHFAHVKHIFKENDRQNQ
GRITIEEFRAIYRCIVHREEITEIFNTYTENRKILSENSLIEFLTQEQYEMEIDHSDSVE
IINKYEPIEEVKGERQMSIEGFARYMFSSECLLFKENCKTVYQDMNHPLSDYFISSSHNT
YLISDQILGPSDIWGYVSALVKGCRCLEIDCWDGSQNEPIVYHGYTFTSKLLFKTVVQAI
NKYAFVTSDYPVVLSLENHCSPGQQEVMASILQSTFGDFLLSDMLEEFPDTLPSPEALKF
KILVKNRKVGTLSETHERIGTDKSGQVLEWKEVIYEDGDEDSGMDPETWDVFLSRIKEER
EADPSTLSGIAGVKKRKRKMKIAMALSDLVIYTKAEKFRNFQYSRVYQQFNETNSIGESR
ARKLSKLRVHEFIFHTAAFITRVYPKMMRADSSNFNPQEFWNVGCQMVALNFQTPGLPMD
LQNGKFLDNGGSGYILKPDILRDTTLGFNPNEPEYDDHPVTLTIRIISGIQLPVSSSSNT
PDIVVIIEVYGVPNDHVKQQTRVVKNNAFSPKWNETFTFLIQVPELALIRFVVETQQGLL
SGNELLGQYTLPVLCMNKGYRRVPLFSKSGANLEPSSLFIYVWYFRE
NT seq 1944 nt   +upstreamnt  +downstreamnt
atggaaagccaacttcatgagctcgcagaagcaagatggtttttgtcaaaggttcaggat
gattttagaggtggaaaaatcaacgttgaaattactcacaaactgcttgagaaacttgat
ttcccatgccactttgctcatgtgaaacatatttttaaggaaaatgacagacagaaccaa
ggaagaatcaccattgaagagtttagagccatttaccggtgtattgtacatagagaagaa
atcacggagattttcaacacgtatactgaaaataggaaaattctttctgagaacagtctg
attgagtttctaacccaagagcagtatgaaatggagatcgatcactctgattcagtagag
atcatcaataagtatgagcccattgaagaagtaaagggtgagcgacagatgtcaattgaa
ggtttcgcaagatacatgttttcatcagaatgtctactgtttaaagagaactgtaaaacc
gtgtaccaagatatgaatcatccattaagtgattattttatttcatcatctcacaacaca
tatttgatatccgatcaaatattgggaccgagtgacatttggggatatgtaagtgctctt
gtgaaaggctgccgctgtctggaaattgactgctgggatggatcccaaaatgaacccatt
gtgtaccatggttacacattcaccagcaagcttctcttcaaaactgtggtccaagcaata
aacaagtatgcctttgtgacatctgattacccagtagtgctgtccttagaaaatcactgc
tcccctggtcagcaggaagtgatggctagcattctgcagagcacctttggagacttcctg
ctttcggacatgcttgaggagtttccagatacactaccgtctccagaggcactaaaattc
aaaatattagtgaaaaacaggaaagtgggaaccttatctgaaacccacgagaggatagga
accgacaaaagtggccaagtgctagaatggaaagaagtcatctatgaagatggtgatgaa
gactcaggaatggatccagaaacatgggatgtcttcctatcacggatcaaggaggagagg
gaagcagatccctcgacattgagtggaatagcaggcgtcaagaaaaggaagaggaagatg
aaaatagccatggccttatctgatcttgtcatttatactaaggctgagaagttccgaaac
ttccaatattcaagagtctatcagcaatttaatgagaccaattcgattggagagtctcga
gctcgaaaactttccaaattgagagtccatgagtttattttccacaccgcggcattcatc
accagagtataccccaaaatgatgagagcagactcttctaactttaaccctcaagagttt
tggaatgtaggatgtcagatggtggccttgaactttcaaacccctggactgcctatggat
ttgcaaaacgggaaatttttggataatggaggctctggatatattttgaagccagacatc
cttagagatacaaccctgggctttaacccaaatgaaccagaatatgacgaccatccagtt
accctcacaatccgaatcatcagtgggatccagttgcctgttagctcatcctctaacacg
cctgacatagtagtgatcatagaagtctacggtgttccaaacgaccacgtgaagcagcag
actcgtgttgttaagaataatgcttttagtccaaagtggaatgaaacatttacatttctt
attcaagtgccagaactggcattgatacgttttgttgttgaaactcaacaaggcttatta
tcaggaaatgaattactcgggcagtacactttaccagttctttgcatgaacaaaggttat
cgtcgtgttcctctgttttccaaatccggtgcgaaccttgaaccttcctcactgtttatt
tatgtttggtacttcagagagtga

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